DE1177643B - Verfahren zur Herstellung von 4,5-Dihydrouracil - Google Patents
Verfahren zur Herstellung von 4,5-DihydrouracilInfo
- Publication number
- DE1177643B DE1177643B DEB67149A DEB0067149A DE1177643B DE 1177643 B DE1177643 B DE 1177643B DE B67149 A DEB67149 A DE B67149A DE B0067149 A DEB0067149 A DE B0067149A DE 1177643 B DE1177643 B DE 1177643B
- Authority
- DE
- Germany
- Prior art keywords
- dihydrouracil
- urea
- acrylic acid
- sulfuric acid
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OIVLITBTBDPEFK-UHFFFAOYSA-N 5,6-dihydrouracil Chemical compound O=C1CCNC(=O)N1 OIVLITBTBDPEFK-UHFFFAOYSA-N 0.000 title claims description 11
- 238000000034 method Methods 0.000 title claims description 7
- 238000002360 preparation method Methods 0.000 title description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 15
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 11
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 11
- 239000004202 carbamide Substances 0.000 claims description 11
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- AKEJUJNQAAGONA-UHFFFAOYSA-N sulfur trioxide Chemical compound O=S(=O)=O AKEJUJNQAAGONA-UHFFFAOYSA-N 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 description 5
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 4
- 239000011541 reaction mixture Substances 0.000 description 3
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 229960003753 nitric oxide Drugs 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- -1 4,5-dihydrouracil 4,5-dihydrouracil Chemical compound 0.000 description 1
- 241000589614 Pseudomonas stutzeri Species 0.000 description 1
- 125000005396 acrylic acid ester group Chemical group 0.000 description 1
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 description 1
- SNCZNSNPXMPCGN-UHFFFAOYSA-N butanediamide Chemical compound NC(=O)CCC(N)=O SNCZNSNPXMPCGN-UHFFFAOYSA-N 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000011874 heated mixture Substances 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- ORQYPOUSZINNCB-UHFFFAOYSA-N potassium;hypobromite Chemical compound [K+].Br[O-] ORQYPOUSZINNCB-UHFFFAOYSA-N 0.000 description 1
- SGLDQLCVBBVVAJ-UHFFFAOYSA-N prop-2-enamide;sulfuric acid Chemical compound NC(=O)C=C.OS(O)(=O)=O SGLDQLCVBBVVAJ-UHFFFAOYSA-N 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000000967 suction filtration Methods 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE637200D BE637200A (enrdf_load_stackoverflow) | 1962-05-08 | ||
| DEB67149A DE1177643B (de) | 1962-05-08 | 1962-05-08 | Verfahren zur Herstellung von 4,5-Dihydrouracil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB67149A DE1177643B (de) | 1962-05-08 | 1962-05-08 | Verfahren zur Herstellung von 4,5-Dihydrouracil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1177643B true DE1177643B (de) | 1964-09-10 |
Family
ID=6975412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEB67149A Pending DE1177643B (de) | 1962-05-08 | 1962-05-08 | Verfahren zur Herstellung von 4,5-Dihydrouracil |
Country Status (2)
| Country | Link |
|---|---|
| BE (1) | BE637200A (enrdf_load_stackoverflow) |
| DE (1) | DE1177643B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0103436A3 (en) * | 1982-08-31 | 1985-07-03 | Sagami Chemical Research Center | Process for preparing 5-perfluoroalkyl-5,6-dihydrouracil derivatives and compounds for use therein |
-
0
- BE BE637200D patent/BE637200A/xx unknown
-
1962
- 1962-05-08 DE DEB67149A patent/DE1177643B/de active Pending
Non-Patent Citations (1)
| Title |
|---|
| None * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0103436A3 (en) * | 1982-08-31 | 1985-07-03 | Sagami Chemical Research Center | Process for preparing 5-perfluoroalkyl-5,6-dihydrouracil derivatives and compounds for use therein |
Also Published As
| Publication number | Publication date |
|---|---|
| BE637200A (enrdf_load_stackoverflow) |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE1177643B (de) | Verfahren zur Herstellung von 4,5-Dihydrouracil | |
| CH646438A5 (en) | Process for the preparation of cobalt dicyclopentadienyl | |
| CH660361A5 (de) | Verfahren zur herstellung von 2,6-difluorbenzonitril. | |
| DE2453365A1 (de) | Verfahren zur herstellung von n-trimethylsilylacetamid | |
| CH412913A (de) | Verfahren zur Herstellung von 4,5-Dihydrouracil | |
| DE1146870B (de) | Verfahren zur Herstellung von Propensulton | |
| DE958833C (de) | Verfahren zur Herstellung von Nitroguanidin | |
| AT212301B (de) | Verfahren zur Herstellung von neuen Anilindisulfonsäurechlorid-Derivaten | |
| AT268319B (de) | Verfahren zur Herstellung von Nitrosylhydrogenpyrosulfat | |
| DE956046C (de) | Verfahren zur Herstellung von Diphenylamin und kernalkylsubstituierten Diphenylaminen | |
| AT213388B (de) | Verfahren zur Herstellung von neuen 3-Nitro-azacyclo-alkanon-2-N-carbochloriden | |
| DE2758397A1 (de) | Verfahren zur herstellung von chinizarin (1,4-dihydroxyanthrachinon) | |
| DE1670232C3 (de) | Verfahren zur Herstellung von 2,4-Hexahydropyrimidind ionen | |
| DE2806038C2 (de) | Verfahren zur Herstellung von Nitroguanidin | |
| DE3014972A1 (de) | Verfahren zur herstellung von 2,4-dinitro-6-bromanilin | |
| DE1096339B (de) | Verfahren zur Herstellung von Peroxymonophosphorsaeure | |
| DE968904C (de) | Verfahren zur Herstellung von N-substituierten Monoureinen des Glyoxals | |
| EP0029495A1 (de) | Verfahren zur Herstellung von 3-Cyanopropionsäureamid | |
| DE2014566A1 (en) | Improved prepn of 1,4-dioxyanthraquinone | |
| DE605307C (de) | Verfahren zur Herstellung von Glycerinsaeure | |
| DE1940704C3 (de) | Verfahren zur Herstellung von 2-Mercaptoinosin | |
| DE765011C (de) | Verfahren zur Herstellung von aliphatischen Dicarbonsaeuren | |
| DE291490C (enrdf_load_stackoverflow) | ||
| DE1081452B (de) | Verfahren zur Herstellung von Alkalisalzen der Benzol-1, 4-disulfonsaeure bzw. der 2, 6-Naphthalindisulfonsaeure | |
| DE1670261A1 (de) | Verfahren zur Herstellung von N-Hexahydropyrimidyl-(4)-carbamin-saeureestern |