DE10212526A1 - Herstellung von verfestigten organischen Verbindungen, insbesondere von Carbonsäureamiden - Google Patents
Herstellung von verfestigten organischen Verbindungen, insbesondere von CarbonsäureamidenInfo
- Publication number
- DE10212526A1 DE10212526A1 DE10212526A DE10212526A DE10212526A1 DE 10212526 A1 DE10212526 A1 DE 10212526A1 DE 10212526 A DE10212526 A DE 10212526A DE 10212526 A DE10212526 A DE 10212526A DE 10212526 A1 DE10212526 A1 DE 10212526A1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- reactor
- organic
- organic compound
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000002894 organic compounds Chemical class 0.000 title claims abstract description 16
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 12
- 150000003857 carboxamides Chemical class 0.000 title claims description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 21
- 238000000034 method Methods 0.000 claims abstract description 20
- 238000001816 cooling Methods 0.000 claims abstract description 12
- 239000007788 liquid Substances 0.000 claims abstract description 11
- 239000007787 solid Substances 0.000 claims abstract description 8
- 239000000203 mixture Substances 0.000 claims abstract description 7
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims abstract description 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 6
- 150000001412 amines Chemical class 0.000 claims abstract description 5
- 238000009835 boiling Methods 0.000 claims description 8
- 229910052739 hydrogen Inorganic materials 0.000 claims description 8
- 239000012535 impurity Substances 0.000 claims description 7
- 239000001257 hydrogen Substances 0.000 claims description 6
- 229910052731 fluorine Inorganic materials 0.000 claims description 5
- 150000002148 esters Chemical class 0.000 claims description 4
- 125000001153 fluoro group Chemical group F* 0.000 claims description 4
- 238000002844 melting Methods 0.000 claims description 4
- 230000008018 melting Effects 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 150000002431 hydrogen Chemical class 0.000 claims description 3
- 125000003118 aryl group Chemical group 0.000 claims description 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
- 239000011737 fluorine Substances 0.000 claims description 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
- 125000006239 protecting group Chemical class 0.000 claims description 2
- 150000001408 amides Chemical class 0.000 abstract description 9
- 150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000010626 work up procedure Methods 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 description 11
- 238000003860 storage Methods 0.000 description 7
- STSCVKRWJPWALQ-UHFFFAOYSA-N TRIFLUOROACETIC ACID ETHYL ESTER Chemical compound CCOC(=O)C(F)(F)F STSCVKRWJPWALQ-UHFFFAOYSA-N 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 239000002245 particle Substances 0.000 description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 description 4
- 239000002826 coolant Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 2
- IQNHBUQSOSYAJU-UHFFFAOYSA-N 2,2,2-trifluoro-n-methylacetamide Chemical compound CNC(=O)C(F)(F)F IQNHBUQSOSYAJU-UHFFFAOYSA-N 0.000 description 2
- -1 N, N-disubstituted amides Chemical class 0.000 description 2
- 229910021529 ammonia Inorganic materials 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000000543 intermediate Substances 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- QAEDZJGFFMLHHQ-UHFFFAOYSA-N trifluoroacetic anhydride Chemical compound FC(F)(F)C(=O)OC(=O)C(F)(F)F QAEDZJGFFMLHHQ-UHFFFAOYSA-N 0.000 description 2
- NRKYWOKHZRQRJR-UHFFFAOYSA-N 2,2,2-trifluoroacetamide Chemical compound NC(=O)C(F)(F)F NRKYWOKHZRQRJR-UHFFFAOYSA-N 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical class CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- BQPIYDUNTQHZBF-UHFFFAOYSA-N n,n-difluorocarbamoyl fluoride Chemical class FN(F)C(F)=O BQPIYDUNTQHZBF-UHFFFAOYSA-N 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
- B01J19/22—Stationary reactors having moving elements inside in the form of endless belts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/06—Solidifying liquids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10212526A DE10212526A1 (de) | 2002-03-21 | 2002-03-21 | Herstellung von verfestigten organischen Verbindungen, insbesondere von Carbonsäureamiden |
| EP03717205A EP1490329A1 (de) | 2002-03-21 | 2003-03-11 | Herstellung von carbonsäureamiden |
| AU2003221495A AU2003221495A1 (en) | 2002-03-21 | 2003-03-11 | Production of carboxylic acid amides |
| JP2003578319A JP2005533006A (ja) | 2002-03-21 | 2003-03-11 | カルボン酸アミドの製造 |
| PCT/EP2003/002453 WO2003080563A1 (de) | 2002-03-21 | 2003-03-11 | Herstellung von carbonsäureamiden |
| US10/944,418 US20050267290A1 (en) | 2002-03-21 | 2004-09-20 | Preparation of acid amides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10212526A DE10212526A1 (de) | 2002-03-21 | 2002-03-21 | Herstellung von verfestigten organischen Verbindungen, insbesondere von Carbonsäureamiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10212526A1 true DE10212526A1 (de) | 2003-10-02 |
Family
ID=27797999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10212526A Withdrawn DE10212526A1 (de) | 2002-03-21 | 2002-03-21 | Herstellung von verfestigten organischen Verbindungen, insbesondere von Carbonsäureamiden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050267290A1 (https=) |
| EP (1) | EP1490329A1 (https=) |
| JP (1) | JP2005533006A (https=) |
| AU (1) | AU2003221495A1 (https=) |
| DE (1) | DE10212526A1 (https=) |
| WO (1) | WO2003080563A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2440518B1 (de) | 2009-06-08 | 2014-08-20 | Bayer Cropscience AG | Verfahren zur herstellung von fluoralkylnitrilen |
| DE102013206447A1 (de) | 2013-04-11 | 2014-10-16 | Bayer Cropscience Ag | Verfahren zur Synthese von Carbonsäureamiden |
| WO2018019693A1 (de) | 2016-07-28 | 2018-02-01 | Bayer Cropscience Aktiengesellschaft | Verfahren zur herstellung von fluoralkylnitrilen und den entsprechenden fluoralkyltetrazolen |
| JP6446744B2 (ja) * | 2017-01-26 | 2019-01-09 | 株式会社先進工学研究所 | 脂肪酸アミドの製造方法 |
| EP3589612B9 (de) | 2017-02-28 | 2021-08-18 | Bayer CropScience Aktiengesellschaft | Verfahren zur herstellung von fluoralkylnitrilen und den entsprechenden fluoralkyltetrazolen |
| CN108489238A (zh) * | 2018-04-27 | 2018-09-04 | 浙江嘉化新材料有限公司 | 对甲苯磺酰胺连续干燥方法 |
| KR102725175B1 (ko) | 2018-09-03 | 2024-11-04 | 피아이 인더스트리스 엘티디. | 플루오로알킬 니트릴의 제조방법 및 이의 상응하는 플루오로알킬 테트라졸을 제조하기 위한 용도 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2730543A (en) * | 1950-05-20 | 1956-01-10 | Minnesota Mining & Mfg | Fluorinated nitriles |
| US4655932A (en) * | 1986-02-10 | 1987-04-07 | Don Roslonski | Method and apparatus for the disintegration and destruction of hazardous and toxic sludge materials |
-
2002
- 2002-03-21 DE DE10212526A patent/DE10212526A1/de not_active Withdrawn
-
2003
- 2003-03-11 JP JP2003578319A patent/JP2005533006A/ja active Pending
- 2003-03-11 EP EP03717205A patent/EP1490329A1/de not_active Withdrawn
- 2003-03-11 AU AU2003221495A patent/AU2003221495A1/en not_active Abandoned
- 2003-03-11 WO PCT/EP2003/002453 patent/WO2003080563A1/de not_active Ceased
-
2004
- 2004-09-20 US US10/944,418 patent/US20050267290A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003221495A1 (en) | 2003-10-08 |
| JP2005533006A (ja) | 2005-11-04 |
| WO2003080563A1 (de) | 2003-10-02 |
| US20050267290A1 (en) | 2005-12-01 |
| EP1490329A1 (de) | 2004-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0005810B1 (de) | Verfahren zur Herstellung organischer Fluorverbindungen | |
| EP1636168B1 (de) | Verfahren zur kontinuierlichen herstellung von alkylamino(meth)acrylamiden | |
| EP2922819B1 (de) | Verfahren zur reinigung von n-alkyl-pyrrolidonen | |
| DE10212526A1 (de) | Herstellung von verfestigten organischen Verbindungen, insbesondere von Carbonsäureamiden | |
| EP1814844B1 (de) | Verfahren zur kontinuierlichen herstellung von alkylaminoacrylamiden | |
| DE2716540A1 (de) | Verfahren zur herstellung von aromatischen urethanen | |
| EP2794553B1 (de) | Verfahren zur herstellung von n-alkyl(meth)acrylamiden | |
| DE1954727A1 (de) | Verfahren zum Herstellen von Aminosaeuren | |
| AT398762B (de) | Verfahren zur herstellung von isocyanaten durch zersetzung von n,n,n'-trisubstituierten harnstoffen | |
| DE765203C (de) | Verfahren zur Herstellung von Piperidonen und Piperidinen | |
| DE2743610C3 (de) | Verfahren zur Herstellung von chlorsubstituierten aromatischen Aminen | |
| EP1439170B1 (de) | Fluorierungsmittel und verfahren zu deren herstellung | |
| DE866647C (de) | Verfahren zur Herstellung von sekundaeren 1, 3-Alkendiaminen | |
| DE2749415C2 (de) | Verfahren zur Herstellung von Aminen aus Formamiden | |
| DE2361604C3 (de) | Verfahren zur Herstellung von N1Ndisubstituierten Carbonsäureamiden | |
| WO2003099768A1 (de) | Verfahren zur reduzierung des gehalts an einem ungesättigten amin in einer mischung enthaltend ein aminonitril, ein diamin, ein dinitril oder deren gemische | |
| DE940528C (de) | Verfahren zur Herstellung von Acrylsaeureamid und ª‡-substituierten Acrylsaeureamiden | |
| EP2450334A1 (de) | Verfahren zur Trennung von isomeren Mentholverbindungen | |
| WO1994017033A1 (de) | Verfahren zur herstellung c-substituierter diethylentriamine | |
| AT323123B (de) | Verfahren zur herstellung von n,n-disubstituierten charbonsäureamiden | |
| AT165057B (de) | Verfahren zur Herstellung neuer Amine | |
| AT251600B (de) | Verfahren zur Herstellung von neuen Oxazolylurethanen | |
| DE1001995B (de) | Verfahren zur Herstellung von N-substituierten Aminocarbonsaeuren | |
| DE1202283B (de) | Verfahren zur Herstellung von 2-(2-Aminophenyl)-acetamiden | |
| DE2316320A1 (de) | Verfahren zur herstellung von 5-amino-2-(beta-cyanoaethyl)-5-cyclohexen-1-on |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8127 | New person/name/address of the applicant |
Owner name: SOLVAY FLUOR GMBH, 30173 HANNOVER, DE |
|
| 8139 | Disposal/non-payment of the annual fee |