DE10161149B4 - Verwendung von Heparin-haltigem Ophthalmikum - Google Patents
Verwendung von Heparin-haltigem Ophthalmikum Download PDFInfo
- Publication number
- DE10161149B4 DE10161149B4 DE10161149A DE10161149A DE10161149B4 DE 10161149 B4 DE10161149 B4 DE 10161149B4 DE 10161149 A DE10161149 A DE 10161149A DE 10161149 A DE10161149 A DE 10161149A DE 10161149 B4 DE10161149 B4 DE 10161149B4
- Authority
- DE
- Germany
- Prior art keywords
- heparin
- hyaluronate
- eye
- pharmaceutical composition
- hyaluronic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10161149A DE10161149B4 (de) | 2001-12-12 | 2001-12-12 | Verwendung von Heparin-haltigem Ophthalmikum |
| US10/496,330 US20050043271A1 (en) | 2001-12-12 | 2002-02-11 | Heparin-containing ophthalmic agent |
| PCT/DE2002/004526 WO2003053452A1 (de) | 2001-12-12 | 2002-12-11 | Heparin-haltiges ophthalmikum |
| AU2002357972A AU2002357972A1 (en) | 2001-12-12 | 2002-12-11 | Heparin-containing ophthalmic agent |
| ES02791625T ES2259727T3 (es) | 2001-12-12 | 2002-12-11 | Agente oftalmico que contiene heparina. |
| DE50205968T DE50205968D1 (de) | 2001-12-12 | 2002-12-11 | Heparin-haltiges ophthalmikum |
| CA002468775A CA2468775A1 (en) | 2001-12-12 | 2002-12-11 | Heparin-containing ophthalmic agent |
| CNA028250079A CN1604784A (zh) | 2001-12-12 | 2002-12-11 | 含有肝素的眼科制剂 |
| EP02791625A EP1453523B1 (de) | 2001-12-12 | 2002-12-11 | Heparin-haltiges ophthalmikum |
| AT02791625T ATE318607T1 (de) | 2001-12-12 | 2002-12-11 | Heparin-haltiges ophthalmikum |
| MXPA04005390A MXPA04005390A (es) | 2001-12-12 | 2002-12-11 | Agente oftalmico que contiene heparina. |
| JP2003554209A JP2005513106A (ja) | 2001-12-12 | 2002-12-11 | ヘパリンを保有する眼薬剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10161149A DE10161149B4 (de) | 2001-12-12 | 2001-12-12 | Verwendung von Heparin-haltigem Ophthalmikum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE10161149A1 DE10161149A1 (de) | 2003-06-26 |
| DE10161149B4 true DE10161149B4 (de) | 2007-03-08 |
Family
ID=7709005
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10161149A Expired - Lifetime DE10161149B4 (de) | 2001-12-12 | 2001-12-12 | Verwendung von Heparin-haltigem Ophthalmikum |
| DE50205968T Expired - Lifetime DE50205968D1 (de) | 2001-12-12 | 2002-12-11 | Heparin-haltiges ophthalmikum |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50205968T Expired - Lifetime DE50205968D1 (de) | 2001-12-12 | 2002-12-11 | Heparin-haltiges ophthalmikum |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050043271A1 (https=) |
| EP (1) | EP1453523B1 (https=) |
| JP (1) | JP2005513106A (https=) |
| CN (1) | CN1604784A (https=) |
| AT (1) | ATE318607T1 (https=) |
| AU (1) | AU2002357972A1 (https=) |
| CA (1) | CA2468775A1 (https=) |
| DE (2) | DE10161149B4 (https=) |
| ES (1) | ES2259727T3 (https=) |
| MX (1) | MXPA04005390A (https=) |
| WO (1) | WO2003053452A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1279406A4 (en) * | 2000-04-03 | 2007-10-24 | Santen Pharmaceutical Co Ltd | TRANSPORTERS AND DRUG DISPENSING SYSTEMS USING THESE |
| WO2004093878A1 (en) * | 2003-04-16 | 2004-11-04 | Alcon, Inc. | Use of fused pyridazine derivatives for treating dry eye disorders |
| DE10360425A1 (de) * | 2003-12-19 | 2005-07-28 | Ursapharm Arzneimittel Gmbh & Co. Kg | Verwendung von Hyaluronsäure, Hyaluronat und/oder deren Derivate zur Herstellung einer pharmazeutischen Zusammensetzung |
| JP2005187407A (ja) * | 2003-12-25 | 2005-07-14 | Lion Corp | アレルギー眼疾患用眼科組成物 |
| DE102004002001A1 (de) * | 2004-01-14 | 2005-08-11 | Reinmüller, Johannes, Dr.med. | Mittel zur Behandlung von entzündlichen Erkrankungen |
| DE102005035986B4 (de) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat |
| DE102005055275A1 (de) * | 2005-11-17 | 2007-05-24 | Ursapharm Arzneimittel Gmbh & Co. Kg | Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung |
| DE102006049091A1 (de) * | 2006-10-18 | 2008-04-24 | Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh | Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl |
| FR2919185B1 (fr) * | 2007-07-23 | 2010-09-10 | Ard Sa | Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses |
| SI2679278T1 (en) * | 2008-11-20 | 2018-02-28 | Laboratori Derivati Organici S.P.A. | Dermatological compositions comprising heparan sulphate |
| WO2010144874A2 (en) | 2009-06-12 | 2010-12-16 | University Of Southern California | Clusterin pharmaceuticals and treatment methods using the same |
| FR2962044B1 (fr) * | 2010-04-21 | 2013-02-22 | Horus Pharma | Emulsion lacrymimetique |
| JP2016185940A (ja) * | 2014-06-10 | 2016-10-27 | ロート製薬株式会社 | 眼科用組成物 |
| DE102016203696A1 (de) | 2016-03-07 | 2017-09-07 | Ursapharm Arzneimittel Gmbh | Ophthalmologische Zusammensetzung |
| US20190240251A1 (en) * | 2016-10-14 | 2019-08-08 | i.com medical GmbH | Method for establishing, restoring, and preserving homeostasis of the ocular surface |
| JP2020525416A (ja) * | 2017-06-29 | 2020-08-27 | アドヴァイテ エルエルシー． | 眼表面障害の治療及び診断 |
| TWI698241B (zh) * | 2017-09-05 | 2020-07-11 | 國立成功大學 | 用於治療缺血的肝素組合物 |
| EP3740191B1 (en) * | 2018-01-18 | 2021-04-28 | Faes Farma, S.A. | Ophthalmic compositions comprising bilastine, a beta-cyclodextrin and at least one gelling agent |
| CN112292135A (zh) | 2018-04-18 | 2021-01-29 | I.Com医疗有限责任公司 | 用于治疗和预防严重眼表疾病的高分子量透明质酸 |
| US12268706B2 (en) | 2019-01-31 | 2025-04-08 | i.com medical GmbH | Hyaluronic acid for relief of idiopathic ocular pain |
| CN116139067B (zh) * | 2021-11-22 | 2024-03-22 | 华熙生物科技股份有限公司 | 透明质酸锌形成凝胶的方法及含有透明质酸锌的滴眼凝胶及其制备 |
| TW202404617A (zh) * | 2022-07-29 | 2024-02-01 | 日商瑪路弘股份有限公司 | 眼科用組成物 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989005646A1 (en) * | 1987-12-21 | 1989-06-29 | Bukh Meditec A/S | Uses of sulphated sugars |
| DE19520575A1 (de) * | 1995-06-06 | 1996-12-12 | Permselect Ges Fuer Zellstrukt | Hautwirksame Kombination von Mucopolysacchariden |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1730M (fr) * | 1962-01-17 | 1963-03-18 | Charles Riviere | Nouvelle composition de collyre. |
| DE3440352A1 (de) * | 1984-11-05 | 1986-05-07 | Dr. Thilo & Co GmbH, 8029 Sauerlach | Dry-eye-packung |
| DE3787188T2 (de) * | 1986-04-04 | 1993-12-16 | Allergan Inc | Zähflüssiges Präparat zur Anwendung bei Wunden in der Augenhornhaut. |
| JPS6479103A (en) * | 1987-06-09 | 1989-03-24 | Lion Corp | External preparation |
| JPH02167233A (ja) * | 1988-11-10 | 1990-06-27 | Kiyoshi Kita | 眼内手術補助剤 |
| US5141741A (en) * | 1988-12-09 | 1992-08-25 | Lion Corporation | Anti-sunburn skin-care preparation |
| US5358706A (en) * | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| IT1273011B (it) * | 1994-07-25 | 1997-07-01 | Trhecnopharma S A | Preparato oftalmico per l'uso come lacrima artificiale |
| DE19547972A1 (de) * | 1995-12-21 | 1997-07-10 | Weropharm Gmbh | Heparin zur Prophylaxe und akuten Therapie der allergischen Konjunktivitis |
| KR100514963B1 (ko) * | 1997-07-11 | 2005-09-15 | 도레이 가부시끼가이샤 | 4,5-에폭시모르피난 유도체를 함유하는 안정한 의약품 조성물 |
| US6348508B1 (en) * | 2000-04-04 | 2002-02-19 | Bausch & Lomb Incorporated | Method for treating dry eye |
-
2001
- 2001-12-12 DE DE10161149A patent/DE10161149B4/de not_active Expired - Lifetime
-
2002
- 2002-02-11 US US10/496,330 patent/US20050043271A1/en not_active Abandoned
- 2002-12-11 AU AU2002357972A patent/AU2002357972A1/en not_active Abandoned
- 2002-12-11 ES ES02791625T patent/ES2259727T3/es not_active Expired - Lifetime
- 2002-12-11 WO PCT/DE2002/004526 patent/WO2003053452A1/de not_active Ceased
- 2002-12-11 AT AT02791625T patent/ATE318607T1/de active
- 2002-12-11 EP EP02791625A patent/EP1453523B1/de not_active Expired - Lifetime
- 2002-12-11 CN CNA028250079A patent/CN1604784A/zh active Pending
- 2002-12-11 DE DE50205968T patent/DE50205968D1/de not_active Expired - Lifetime
- 2002-12-11 JP JP2003554209A patent/JP2005513106A/ja active Pending
- 2002-12-11 MX MXPA04005390A patent/MXPA04005390A/es active IP Right Grant
- 2002-12-11 CA CA002468775A patent/CA2468775A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989005646A1 (en) * | 1987-12-21 | 1989-06-29 | Bukh Meditec A/S | Uses of sulphated sugars |
| DE19520575A1 (de) * | 1995-06-06 | 1996-12-12 | Permselect Ges Fuer Zellstrukt | Hautwirksame Kombination von Mucopolysacchariden |
Non-Patent Citations (2)
| Title |
|---|
| Chem. Abstr. 135:362554 * |
| Chem. Abstr. 135:376728 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2468775A1 (en) | 2003-07-03 |
| CN1604784A (zh) | 2005-04-06 |
| DE50205968D1 (de) | 2006-04-27 |
| ATE318607T1 (de) | 2006-03-15 |
| MXPA04005390A (es) | 2005-10-18 |
| EP1453523A1 (de) | 2004-09-08 |
| JP2005513106A (ja) | 2005-05-12 |
| US20050043271A1 (en) | 2005-02-24 |
| AU2002357972A1 (en) | 2003-07-09 |
| DE10161149A1 (de) | 2003-06-26 |
| WO2003053452A1 (de) | 2003-07-03 |
| EP1453523B1 (de) | 2006-03-01 |
| ES2259727T3 (es) | 2006-10-16 |
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| R071 | Expiry of right |