CN1604784A - 含有肝素的眼科制剂 - Google Patents

含有肝素的眼科制剂 Download PDF

Info

Publication number
CN1604784A
CN1604784A CNA028250079A CN02825007A CN1604784A CN 1604784 A CN1604784 A CN 1604784A CN A028250079 A CNA028250079 A CN A028250079A CN 02825007 A CN02825007 A CN 02825007A CN 1604784 A CN1604784 A CN 1604784A
Authority
CN
China
Prior art keywords
heparin
hyaluronate
pharmaceutical composition
eye
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028250079A
Other languages
English (en)
Chinese (zh)
Inventor
D·格罗布
F·霍尔泽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ursapharm Arzneimittel GmbH
Original Assignee
Ursapharm Arzneimittel GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ursapharm Arzneimittel GmbH filed Critical Ursapharm Arzneimittel GmbH
Publication of CN1604784A publication Critical patent/CN1604784A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CNA028250079A 2001-12-12 2002-12-11 含有肝素的眼科制剂 Pending CN1604784A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10161149A DE10161149B4 (de) 2001-12-12 2001-12-12 Verwendung von Heparin-haltigem Ophthalmikum
DE10161149.8 2001-12-12

Publications (1)

Publication Number Publication Date
CN1604784A true CN1604784A (zh) 2005-04-06

Family

ID=7709005

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028250079A Pending CN1604784A (zh) 2001-12-12 2002-12-11 含有肝素的眼科制剂

Country Status (11)

Country Link
US (1) US20050043271A1 (https=)
EP (1) EP1453523B1 (https=)
JP (1) JP2005513106A (https=)
CN (1) CN1604784A (https=)
AT (1) ATE318607T1 (https=)
AU (1) AU2002357972A1 (https=)
CA (1) CA2468775A1 (https=)
DE (2) DE10161149B4 (https=)
ES (1) ES2259727T3 (https=)
MX (1) MXPA04005390A (https=)
WO (1) WO2003053452A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108778250A (zh) * 2016-03-07 2018-11-09 乌尔萨法姆药物有限责任公司 眼科用组合物

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1279406A4 (en) * 2000-04-03 2007-10-24 Santen Pharmaceutical Co Ltd TRANSPORTERS AND DRUG DISPENSING SYSTEMS USING THESE
WO2004093878A1 (en) * 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
DE10360425A1 (de) * 2003-12-19 2005-07-28 Ursapharm Arzneimittel Gmbh & Co. Kg Verwendung von Hyaluronsäure, Hyaluronat und/oder deren Derivate zur Herstellung einer pharmazeutischen Zusammensetzung
JP2005187407A (ja) * 2003-12-25 2005-07-14 Lion Corp アレルギー眼疾患用眼科組成物
DE102004002001A1 (de) * 2004-01-14 2005-08-11 Reinmüller, Johannes, Dr.med. Mittel zur Behandlung von entzündlichen Erkrankungen
DE102005035986B4 (de) * 2005-07-28 2009-10-15 Bausch & Lomb Incorporated Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
DE102006049091A1 (de) * 2006-10-18 2008-04-24 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl
FR2919185B1 (fr) * 2007-07-23 2010-09-10 Ard Sa Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses
SI2679278T1 (en) * 2008-11-20 2018-02-28 Laboratori Derivati Organici S.P.A. Dermatological compositions comprising heparan sulphate
WO2010144874A2 (en) 2009-06-12 2010-12-16 University Of Southern California Clusterin pharmaceuticals and treatment methods using the same
FR2962044B1 (fr) * 2010-04-21 2013-02-22 Horus Pharma Emulsion lacrymimetique
JP2016185940A (ja) * 2014-06-10 2016-10-27 ロート製薬株式会社 眼科用組成物
US20190240251A1 (en) * 2016-10-14 2019-08-08 i.com medical GmbH Method for establishing, restoring, and preserving homeostasis of the ocular surface
JP2020525416A (ja) * 2017-06-29 2020-08-27 アドヴァイテ エルエルシー． 眼表面障害の治療及び診断
TWI698241B (zh) * 2017-09-05 2020-07-11 國立成功大學 用於治療缺血的肝素組合物
EP3740191B1 (en) * 2018-01-18 2021-04-28 Faes Farma, S.A. Ophthalmic compositions comprising bilastine, a beta-cyclodextrin and at least one gelling agent
CN112292135A (zh) 2018-04-18 2021-01-29 I.Com医疗有限责任公司 用于治疗和预防严重眼表疾病的高分子量透明质酸
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
CN116139067B (zh) * 2021-11-22 2024-03-22 华熙生物科技股份有限公司 透明质酸锌形成凝胶的方法及含有透明质酸锌的滴眼凝胶及其制备
TW202404617A (zh) * 2022-07-29 2024-02-01 日商瑪路弘股份有限公司 眼科用組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1730M (fr) * 1962-01-17 1963-03-18 Charles Riviere Nouvelle composition de collyre.
DE3440352A1 (de) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye-packung
DE3787188T2 (de) * 1986-04-04 1993-12-16 Allergan Inc Zähflüssiges Präparat zur Anwendung bei Wunden in der Augenhornhaut.
JPS6479103A (en) * 1987-06-09 1989-03-24 Lion Corp External preparation
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
JPH02167233A (ja) * 1988-11-10 1990-06-27 Kiyoshi Kita 眼内手術補助剤
US5141741A (en) * 1988-12-09 1992-08-25 Lion Corporation Anti-sunburn skin-care preparation
US5358706A (en) * 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
IT1273011B (it) * 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
DE19520575A1 (de) * 1995-06-06 1996-12-12 Permselect Ges Fuer Zellstrukt Hautwirksame Kombination von Mucopolysacchariden
DE19547972A1 (de) * 1995-12-21 1997-07-10 Weropharm Gmbh Heparin zur Prophylaxe und akuten Therapie der allergischen Konjunktivitis
KR100514963B1 (ko) * 1997-07-11 2005-09-15 도레이 가부시끼가이샤 4,5-에폭시모르피난 유도체를 함유하는 안정한 의약품 조성물
US6348508B1 (en) * 2000-04-04 2002-02-19 Bausch & Lomb Incorporated Method for treating dry eye

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108778250A (zh) * 2016-03-07 2018-11-09 乌尔萨法姆药物有限责任公司 眼科用组合物

Also Published As

Publication number Publication date
CA2468775A1 (en) 2003-07-03
DE50205968D1 (de) 2006-04-27
ATE318607T1 (de) 2006-03-15
MXPA04005390A (es) 2005-10-18
EP1453523A1 (de) 2004-09-08
JP2005513106A (ja) 2005-05-12
US20050043271A1 (en) 2005-02-24
AU2002357972A1 (en) 2003-07-09
DE10161149B4 (de) 2007-03-08
DE10161149A1 (de) 2003-06-26
WO2003053452A1 (de) 2003-07-03
EP1453523B1 (de) 2006-03-01
ES2259727T3 (es) 2006-10-16

Similar Documents

Publication Publication Date Title
CN1604784A (zh) 含有肝素的眼科制剂
CN1310651C (zh) 用于眼科和鼻科的药物组合物
US11633432B2 (en) Amniotic fluid topical formulation
JP7473237B2 (ja) 眼乾燥症候群および他の外傷を受けた非角化上皮表面を処置する組成物および方法
CA3002384C (en) Pharmaceutical formulations that form gel in situ
CN111991415B (zh) 一种眼部护理组合物及其制备方法和用途
US20150031629A1 (en) Ophthalmic formulation derived from silk protein
Bernatchez et al. Use of hyaluronic acid in ocular therapy
CN110090294A (zh) 具有改善的干燥保护和保留的眼用组合物
MXPA03011613A (es) Composicion oftalmica que contiene n-acetil-cisteina para el trtamiento de sindrome de ojo seco.
CN110913867B (zh) 热凝胶化人工泪液
RU2302231C1 (ru) Глазные капли для лечения синдрома сухого глаза
RU2197923C1 (ru) Фармацевтическая композиция для лечения отеков роговицы "осмогель"
KR102268002B1 (ko) 효과 지속성 점안제 조성물
RU2340327C1 (ru) Офтальмологический гель и способ его приготовления
CN1634123A (zh) 含卵磷脂和玻璃酸钠的眼科给药系统及其制备方法
JP2019514887A (ja) グリコーゲンとヒアルロン酸またはその塩との相乗的組み合わせを含む眼科用組成物
HK40009946A (en) Compositions and methods of treating dry eye syndrome and other traumatized non-keratinized epithelial surfaces

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication