DE04752947T1 - Lokalisierte temperaturregelung für raumanordnungen von reaktionsmedien - Google Patents
Lokalisierte temperaturregelung für raumanordnungen von reaktionsmedien Download PDFInfo
- Publication number
- DE04752947T1 DE04752947T1 DE04752947T DE04752947T DE04752947T1 DE 04752947 T1 DE04752947 T1 DE 04752947T1 DE 04752947 T DE04752947 T DE 04752947T DE 04752947 T DE04752947 T DE 04752947T DE 04752947 T1 DE04752947 T1 DE 04752947T1
- Authority
- DE
- Germany
- Prior art keywords
- regions
- heat
- thermoelectric modules
- region
- thermal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012429 reaction media Substances 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 claims abstract 3
- 239000012530 fluid Substances 0.000 claims 6
- 230000008878 coupling Effects 0.000 claims 5
- 238000010168 coupling process Methods 0.000 claims 5
- 238000005859 coupling reaction Methods 0.000 claims 5
- 230000017525 heat dissipation Effects 0.000 claims 4
- 239000007822 coupling agent Substances 0.000 claims 3
- 238000009413 insulation Methods 0.000 claims 3
- 239000006185 dispersion Substances 0.000 claims 2
- 230000005684 electric field Effects 0.000 claims 2
- 239000011810 insulating material Substances 0.000 claims 2
- 239000011553 magnetic fluid Substances 0.000 claims 2
- 239000000696 magnetic material Substances 0.000 claims 2
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000000994 depressogenic effect Effects 0.000 claims 1
- 239000006249 magnetic particle Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 229920000136 polysorbate Polymers 0.000 claims 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/54—Heating or cooling apparatus; Heat insulating devices using spatial temperature gradients
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1883—Means for temperature control using thermal insulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Control Of Temperature (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47296403P | 2003-05-23 | 2003-05-23 | |
| US472964P | 2003-05-23 | ||
| PCT/US2004/016025 WO2004105947A2 (en) | 2003-05-23 | 2004-05-20 | Localized temperature control for spatial arrays of reaction media |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE04752947T1 true DE04752947T1 (de) | 2006-11-16 |
Family
ID=33490545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE04752947T Pending DE04752947T1 (de) | 2003-05-23 | 2004-05-20 | Lokalisierte temperaturregelung für raumanordnungen von reaktionsmedien |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7771933B2 (enExample) |
| EP (1) | EP1641563B1 (enExample) |
| JP (1) | JP4705035B2 (enExample) |
| AU (1) | AU2004243070B2 (enExample) |
| CA (1) | CA2523040C (enExample) |
| DE (1) | DE04752947T1 (enExample) |
| WO (1) | WO2004105947A2 (enExample) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8676383B2 (en) * | 2002-12-23 | 2014-03-18 | Applied Biosystems, Llc | Device for carrying out chemical or biological reactions |
| AU2004243070B2 (en) * | 2003-05-23 | 2010-04-15 | Bio-Rad Laboratories, Inc. | Localized temperature control for spatial arrays of reaction media |
| US20040241048A1 (en) | 2003-05-30 | 2004-12-02 | Applera Corporation | Thermal cycling apparatus and method for providing thermal uniformity |
| JP4695851B2 (ja) * | 2003-07-10 | 2011-06-08 | シチズンホールディングス株式会社 | マイクロ化学チップ温度調節装置 |
| US7833709B2 (en) | 2004-05-28 | 2010-11-16 | Wafergen, Inc. | Thermo-controllable chips for multiplex analyses |
| EP1710017B1 (en) | 2005-04-04 | 2012-12-19 | Roche Diagnostics GmbH | Thermocycling of a block comprising multiple samples |
| CN100405625C (zh) * | 2005-07-18 | 2008-07-23 | 财团法人工业技术研究院 | 制作微型热电元件的方法及其整合热电元件的结构 |
| WO2007072417A2 (en) * | 2005-12-22 | 2007-06-28 | Koninklijke Philips Electronics N.V. | Ink jet device for the positioning of a substance onto a substrate, method for the positioning of a substance onto a substrate and use of an ink jet device |
| EP2027251A4 (en) * | 2006-05-17 | 2010-05-05 | California Inst Of Techn | Thermal cycling system |
| US8232091B2 (en) | 2006-05-17 | 2012-07-31 | California Institute Of Technology | Thermal cycling system |
| US8815162B2 (en) | 2006-06-08 | 2014-08-26 | Koninklijke Philips N.V. | Microelectronic sensor device for DNA detection |
| US7629124B2 (en) * | 2006-06-30 | 2009-12-08 | Canon U.S. Life Sciences, Inc. | Real-time PCR in micro-channels |
| WO2008014389A2 (en) * | 2006-07-26 | 2008-01-31 | Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations | Streaming-based micro/mini channel electronic cooling techniques |
| WO2008091626A1 (en) | 2007-01-22 | 2008-07-31 | Wafergen, Inc. | Apparatus for high throughput chemical reactions |
| US9475051B2 (en) | 2007-02-27 | 2016-10-25 | Sony Corporation | Nucleic acid amplifier |
| WO2008127330A1 (en) * | 2007-04-12 | 2008-10-23 | Duke Manufacturing Co. | A food serving bar |
| US7958736B2 (en) * | 2007-05-24 | 2011-06-14 | Bio-Rad Laboratories, Inc. | Thermoelectric device and heat sink assembly with reduced edge heat loss |
| JP5045268B2 (ja) * | 2007-06-28 | 2012-10-10 | ソニー株式会社 | 反応処理装置 |
| JP4969650B2 (ja) * | 2007-06-29 | 2012-07-04 | 凸版印刷株式会社 | 遺伝子検出判定装置および遺伝子検出判定方法並びに遺伝子反応装置 |
| WO2009034988A1 (ja) * | 2007-09-14 | 2009-03-19 | Shimane Prefectural Government | Pcr用温度制御装置 |
| EP2060324A1 (en) | 2007-11-13 | 2009-05-20 | F.Hoffmann-La Roche Ag | Thermal block unit |
| US9034635B2 (en) * | 2008-02-20 | 2015-05-19 | Streck, Inc. | Thermocycler and sample vessel for rapid amplification of DNA |
| DE102008023299A1 (de) * | 2008-05-08 | 2009-11-19 | Micropelt Gmbh | Aufnahme für eine Probe |
| EP2127751B1 (en) * | 2008-05-19 | 2012-05-16 | Roche Diagnostics GmbH | Improved cooler / heater arrangement with solid film lubricant |
| EP2123360A1 (en) | 2008-05-20 | 2009-11-25 | F.Hoffmann-La Roche Ag | Thermocycling device having a thermocycler module with a thermal switch, method of cooling a heating block in a thermocycler module of a thermocycling device and analytical apparatus |
| CN102083954B (zh) * | 2008-07-05 | 2014-09-03 | 尤尼森斯繁殖技术公司 | 一对一识别系统 |
| CN102164674B (zh) * | 2008-09-23 | 2014-07-16 | 皇家飞利浦电子股份有限公司 | 热循环设备 |
| TWI368651B (en) * | 2008-10-24 | 2012-07-21 | Quanta Comp Inc | Temperature variation apparatus |
| EP2301666B1 (en) | 2009-09-09 | 2021-06-30 | Cole-Parmer Ltd. | Optical system for multiple reactions |
| CN102021114B (zh) * | 2009-09-23 | 2013-08-21 | 清华大学 | 聚合酵素连锁反应器 |
| DE102010003365A1 (de) * | 2010-03-26 | 2011-09-29 | Micropelt Gmbh | Vorrichtung zur Durchführung der PCR und PCR-Verfahren |
| WO2011127386A2 (en) | 2010-04-09 | 2011-10-13 | Life Technologies Corporation | Improved thermal uniformity for thermal cycler instrumentation using dynamic control |
| EA201291008A1 (ru) * | 2010-04-30 | 2013-05-30 | Бигтек Прайвит Лимитед | Система для бесконтактной микро-пцр в реальном времени и способ её применения |
| JP5249988B2 (ja) * | 2010-05-07 | 2013-07-31 | 株式会社日立ハイテクノロジーズ | 核酸増幅装置及びそれを用いた核酸検査装置 |
| JP5582049B2 (ja) * | 2010-05-31 | 2014-09-03 | 横河電機株式会社 | 化学処理用カートリッジシステム |
| JP5689274B2 (ja) * | 2010-10-05 | 2015-03-25 | 株式会社日立ハイテクノロジーズ | 核酸検査装置及び容器搬送方法 |
| JP5931910B2 (ja) * | 2010-12-17 | 2016-06-08 | ビージェイエス アイピー リミテッド | 高速pcr加熱のための方法及びシステム |
| US9168531B2 (en) * | 2011-03-24 | 2015-10-27 | Fluidigm Corporation | Method for thermal cycling of microfluidic samples |
| CA2832759A1 (en) * | 2011-05-06 | 2012-11-15 | Bio-Rad Laboratories, Inc. | Thermal cycler with vapor chamber for rapid temperature changes |
| CA2835654A1 (en) | 2011-06-01 | 2012-12-06 | Streck, Inc. | Rapid thermocycler system for rapid amplification of nucleic acids and related methods |
| US20130137144A1 (en) * | 2011-06-08 | 2013-05-30 | Bio-Rad Laboratories, Inc. LSG - GXD Division | Thermal block with built-in thermoelectric elements |
| WO2012176596A1 (ja) * | 2011-06-24 | 2012-12-27 | 株式会社日立ハイテクノロジーズ | 核酸増幅装置及び核酸分析装置 |
| US20130005372A1 (en) | 2011-06-29 | 2013-01-03 | Rosemount Inc. | Integral thermoelectric generator for wireless devices |
| JP5759818B2 (ja) * | 2011-07-25 | 2015-08-05 | 株式会社日立ハイテクノロジーズ | 核酸検査装置 |
| DE102011119174A1 (de) | 2011-11-23 | 2013-05-23 | Inheco Industrial Heating And Cooling Gmbh | Vapor Chamber |
| EP2608088B1 (en) | 2011-12-20 | 2018-12-12 | F. Hoffmann-La Roche AG | Improved method for nucleic acid analysis |
| US8397518B1 (en) | 2012-02-20 | 2013-03-19 | Dhama Innovations PVT. Ltd. | Apparel with integral heating and cooling device |
| HK1207597A1 (en) | 2012-05-24 | 2016-02-05 | Bjs Ip Limited | Clamp for fast pcr heating |
| KR20150034801A (ko) * | 2012-07-31 | 2015-04-03 | 쓰리엠 이노베이티브 프로퍼티즈 캄파니 | 열적 제어가능 어레이를 포함하는 몰드 공동 표면을 포함하는 사출 성형 장치 및 방법 |
| AU2013202793B2 (en) | 2012-07-31 | 2014-09-18 | Gen-Probe Incorporated | System, method and apparatus for automated incubation |
| AU2013202808B2 (en) * | 2012-07-31 | 2014-11-13 | Gen-Probe Incorporated | System and method for performing multiplex thermal melt analysis |
| JP5801334B2 (ja) * | 2013-03-08 | 2015-10-28 | 株式会社日立ハイテクノロジーズ | 核酸増幅装置及びそれを用いた核酸検査装置 |
| AU2013202805B2 (en) | 2013-03-14 | 2015-07-16 | Gen-Probe Incorporated | System and method for extending the capabilities of a diagnostic analyzer |
| US10006861B2 (en) | 2013-06-28 | 2018-06-26 | Streck, Inc. | Devices for real-time polymerase chain reaction |
| EP3044595B1 (en) | 2013-09-12 | 2018-07-25 | Siemens Healthcare Diagnostics Inc. | Dynamic assay selection and sample preparation apparatus and methods and machine-readable mediums thereof |
| KR20160055248A (ko) | 2013-09-16 | 2016-05-17 | 라이프 테크놀로지스 코포레이션 | 유전자증폭기에 열 균일성을 제공하기 위한 장치, 시스템 및 방법 |
| JP5820459B2 (ja) * | 2013-12-18 | 2015-11-24 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | サーモサイクルデバイス |
| MX2016010721A (es) * | 2014-02-18 | 2016-11-23 | Life Technologies Corp | Aparatos, sistemas y metodos para proveer cicladores termicos escalables y aislar dispositivos termoelectricos. |
| CN103990501A (zh) * | 2014-06-18 | 2014-08-20 | 云南师范大学 | 一种高效传热与热隔离的微热控芯片系统 |
| DE102014018308A1 (de) * | 2014-12-10 | 2016-06-16 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Temperierkörper für eine Multiwell-Platte und Verfahren und Vorrichtung zum Einfrieren und/oder Auftauen von biologischen Proben |
| EP3245283B1 (en) * | 2015-01-16 | 2020-09-23 | The Regents of The University of California | Led driven plasmonic heating apparatus for nucleic acids amplification |
| EP3822361A1 (en) | 2015-02-20 | 2021-05-19 | Takara Bio USA, Inc. | Method for rapid accurate dispensing, visualization and analysis of single cells |
| US9585237B2 (en) * | 2015-04-09 | 2017-02-28 | Honeywell International Inc. | Micro-structured atomic source system |
| JP2017146127A (ja) * | 2016-02-15 | 2017-08-24 | 株式会社島津製作所 | 成分抽出装置 |
| WO2018017892A1 (en) | 2016-07-21 | 2018-01-25 | Takara Bio Usa, Inc. | Multi-z imaging and dispensing with multi-well devices |
| US11420209B2 (en) | 2016-08-22 | 2022-08-23 | Biocontrol Systems, Inc. | Variable spacing rack |
| EP3290119B1 (en) * | 2016-09-01 | 2019-06-26 | Roche Diagniostics GmbH | Assembly, instrument for performing a temperature-dependent reaction and method for performing a temperature-dependent reaction in an assembly |
| EP3519098B1 (en) | 2016-09-29 | 2024-07-03 | DIALUNOX GmbH | Sample container arrangement |
| CN110168344A (zh) * | 2017-05-29 | 2019-08-23 | 株式会社岛津制作所 | 成分萃取装置 |
| US10527355B2 (en) | 2017-06-13 | 2020-01-07 | Microsoft Technology Licensing, Llc | Devices, methods, and systems for thermal management |
| US20190004576A1 (en) * | 2017-06-30 | 2019-01-03 | Microsoft Technology Licensing, Llc | Adaptive cooling heat spreader |
| WO2019056168A1 (zh) * | 2017-09-19 | 2019-03-28 | 瑞基海洋生物科技股份有限公司 | 生化反应装置的加热机构 |
| US10511135B2 (en) | 2017-12-19 | 2019-12-17 | Raytheon Company | Laser system with mechanically-robust monolithic fused planar waveguide (PWG) structure |
| JP2021518158A (ja) | 2018-03-15 | 2021-08-02 | クリプトス バイオテクノロジーズ,インコーポレイテッド | 熱支援生化学反応を実施するための方法およびシステム |
| CN109082373A (zh) * | 2018-08-15 | 2018-12-25 | 湖南圣湘生物科技有限公司 | 生化反应加热装置及其制作方法 |
| US11153941B2 (en) * | 2018-08-31 | 2021-10-19 | The Trustees Of Dartmouth College | Multi-coil induction hob and method |
| US11549731B2 (en) | 2019-01-14 | 2023-01-10 | Bio-Rad Laboratories, Inc. | Heat pump device and assembly |
| JP7300099B2 (ja) * | 2019-02-22 | 2023-06-29 | ウシオ電機株式会社 | 細胞培養チップ |
| KR102204931B1 (ko) * | 2019-03-12 | 2021-01-20 | 퓨쳐이엔지 주식회사 | 독립적 온도 제어가 가능한 pcr용 블록 |
| KR102679722B1 (ko) * | 2019-03-18 | 2024-06-28 | 주식회사 씨젠 | 샘플 홀더 어셈블리를 포함하는 써멀 사이클러 |
| WO2020189690A1 (ja) * | 2019-03-20 | 2020-09-24 | シチズン時計株式会社 | 被測定物質の検出装置及び被測定物質の検出方法 |
| CN110205242B (zh) * | 2019-06-18 | 2024-04-26 | 苏州锐讯生物科技有限公司 | 一种快速实现数字pcr反应的微流控芯片组件及其应用 |
| WO2021100189A1 (ja) * | 2019-11-22 | 2021-05-27 | 株式会社日立ハイテク | Pcr容器、pcr容器支持装置、サーマルサイクラーおよび遺伝子検査装置 |
| US11732964B2 (en) * | 2020-04-15 | 2023-08-22 | Navinta Iii Inc | Lyophilization promoting element |
| EP4405499A4 (en) | 2021-09-23 | 2025-08-06 | N6 Tec Inc | SAMPLE ANALYSIS METHODS AND SYSTEMS |
| WO2024252648A1 (ja) * | 2023-06-09 | 2024-12-12 | 株式会社日立ハイテク | 液体処理装置、核酸抽出装置、及び遺伝子検査装置 |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4042012A (en) * | 1976-08-27 | 1977-08-16 | Electric Power Research Institute | Heat pump system with improved heat transfer |
| US4081143A (en) * | 1977-02-18 | 1978-03-28 | Tire-Gator, Inc. | Methods of handling waste |
| JPS5582091A (en) | 1978-12-15 | 1980-06-20 | Seiko Instr & Electronics Ltd | Automatic clear circuit |
| JPS5849797B2 (ja) * | 1978-12-19 | 1983-11-07 | 松下電器産業株式会社 | ヒ−トパイプ |
| US4481967A (en) * | 1979-11-15 | 1984-11-13 | Rosemount Inc. | Control circuit for current to pressure converter |
| US4341000A (en) * | 1980-03-24 | 1982-07-27 | Combustion Engineering, Inc. | Method of charging heat pipe |
| US4516631A (en) * | 1981-11-04 | 1985-05-14 | Combustion Engineering, Inc. | Nozzle cooled by heat pipe means |
| US4703796A (en) * | 1987-02-27 | 1987-11-03 | Stirling Thermal Motors, Inc. | Corrosion resistant heat pipe |
| JPH01288331A (ja) * | 1988-05-13 | 1989-11-20 | Hitachi Ltd | 熱伝達装置 |
| US4851183A (en) * | 1988-05-17 | 1989-07-25 | The United States Of America As Represented By The United States Department Of Energy | Underground nuclear power station using self-regulating heat-pipe controlled reactors |
| US4970868A (en) * | 1989-06-23 | 1990-11-20 | International Business Machines Corporation | Apparatus for temperature control of electronic devices |
| JP2974337B2 (ja) | 1989-09-10 | 1999-11-10 | キヤノン株式会社 | 自動焦点調節装置 |
| JPH03297378A (ja) * | 1990-04-13 | 1991-12-27 | Seiko Instr Inc | 自動反応装置 |
| US5935522A (en) * | 1990-06-04 | 1999-08-10 | University Of Utah Research Foundation | On-line DNA analysis system with rapid thermal cycling |
| US5498392A (en) * | 1992-05-01 | 1996-03-12 | Trustees Of The University Of Pennsylvania | Mesoscale polynucleotide amplification device and method |
| US5639423A (en) * | 1992-08-31 | 1997-06-17 | The Regents Of The University Of Calfornia | Microfabricated reactor |
| EP0636413B1 (en) * | 1993-07-28 | 2001-11-14 | PE Corporation (NY) | Nucleic acid amplification reaction apparatus and method |
| JP2909216B2 (ja) * | 1994-04-29 | 1999-06-23 | パーキン‐エルマー コーポレイション | 核酸増幅生成物のリアルタイム検出装置 |
| JPH08189788A (ja) * | 1994-12-29 | 1996-07-23 | Ichiro Takahashi | 磁性流体振動型熱拡散方法及び装置 |
| US5598320A (en) * | 1995-03-06 | 1997-01-28 | Ast Research, Inc. | Rotable and slideble heat pipe apparatus for reducing heat build up in electronic devices |
| US5921315A (en) * | 1995-06-07 | 1999-07-13 | Heat Pipe Technology, Inc. | Three-dimensional heat pipe |
| US6524532B1 (en) * | 1995-06-20 | 2003-02-25 | The Regents Of The University Of California | Microfabricated sleeve devices for chemical reactions |
| US5589136A (en) * | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
| US6521181B1 (en) * | 1995-06-20 | 2003-02-18 | The Regents Of The University Of Calfornia | Microfabricated electrochemiluminescence cell for chemical reaction detection |
| US5849208A (en) * | 1995-09-07 | 1998-12-15 | Microfab Technoologies, Inc. | Making apparatus for conducting biochemical analyses |
| US6126899A (en) * | 1996-04-03 | 2000-10-03 | The Perkins-Elmer Corporation | Device for multiple analyte detection |
| DK1179600T3 (da) * | 1996-06-04 | 2005-09-05 | Univ Utah Res Found | Overvågning af hybridisering under PCR |
| US6145688A (en) * | 1996-07-17 | 2000-11-14 | Smith; James C. | Closure device for containers |
| US5817167A (en) * | 1996-08-21 | 1998-10-06 | Des Champs Laboratories Incorporated | Desiccant based dehumidifier |
| DE29623597U1 (de) | 1996-11-08 | 1999-01-07 | Eppendorf - Netheler - Hinz Gmbh, 22339 Hamburg | Temperierblock mit Temperiereinrichtungen |
| JP2874684B2 (ja) * | 1997-03-27 | 1999-03-24 | 日本電気株式会社 | プラグインユニットの放熱構造 |
| ATE211025T1 (de) * | 1997-03-28 | 2002-01-15 | Pe Corp Ny | Thermo-zyklus-vorrichtung zur ausführung der polymerase-kettenreaktion |
| US6939477B2 (en) * | 1997-06-06 | 2005-09-06 | Ashland, Inc. | Temperature-controlled induction heating of polymeric materials |
| US6558947B1 (en) * | 1997-09-26 | 2003-05-06 | Applied Chemical & Engineering Systems, Inc. | Thermal cycler |
| US6210882B1 (en) * | 1998-01-29 | 2001-04-03 | Mayo Foundation For Medical Education And Reseach | Rapid thermocycling for sample analysis |
| US6369893B1 (en) * | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
| WO1999048608A2 (en) * | 1998-03-23 | 1999-09-30 | Cepheid | Multi-site reactor system with dynamic, independent control of individual reaction sites |
| US5947111A (en) * | 1998-04-30 | 1999-09-07 | Hudson Products Corporation | Apparatus for the controlled heating of process fluids |
| US6503750B1 (en) * | 1998-11-25 | 2003-01-07 | The Regents Of The University Of California | PCR thermocycler |
| US6372484B1 (en) * | 1999-01-25 | 2002-04-16 | E.I. Dupont De Nemours And Company | Apparatus for integrated polymerase chain reaction and capillary electrophoresis |
| US6225061B1 (en) * | 1999-03-10 | 2001-05-01 | Sequenom, Inc. | Systems and methods for performing reactions in an unsealed environment |
| EP1045038A1 (en) * | 1999-04-08 | 2000-10-18 | Hans-Knöll-Institut Für Naturstoff-Forschung E.V. | Rapid heat block thermocycler |
| US6706519B1 (en) * | 1999-06-22 | 2004-03-16 | Tecan Trading Ag | Devices and methods for the performance of miniaturized in vitro amplification assays |
| CA2376969A1 (en) * | 1999-07-21 | 2001-02-01 | Dako A/S | A method of controlling the temperature of a specimen in or on a solid support member |
| US6337435B1 (en) | 1999-07-30 | 2002-01-08 | Bio-Rad Laboratories, Inc. | Temperature control for multi-vessel reaction apparatus |
| US6633785B1 (en) * | 1999-08-31 | 2003-10-14 | Kabushiki Kaisha Toshiba | Thermal cycler and DNA amplifier method |
| DE29917313U1 (de) | 1999-10-01 | 2001-02-15 | MWG-BIOTECH AG, 85560 Ebersberg | Vorrichtung zur Durchführung chemischer oder biologischer Reaktionen |
| EP1237655A2 (en) * | 1999-12-09 | 2002-09-11 | Motorola, Inc. | Multilayered microfluidic devices for analyte reactions |
| WO2001051209A1 (de) * | 2000-01-15 | 2001-07-19 | Eppendorf Ag | Labortemperiergerät mit temperaturgeregeltem temperierblock |
| AU2001238638A1 (en) * | 2000-02-23 | 2001-09-03 | Mj Research, Inc. | Thermal cycler that allows two-dimension temperature gradients and hold time optimization |
| US6640891B1 (en) * | 2000-09-05 | 2003-11-04 | Kevin R. Oldenburg | Rapid thermal cycling device |
| US20040043479A1 (en) * | 2000-12-11 | 2004-03-04 | Briscoe Cynthia G. | Multilayerd microfluidic devices for analyte reactions |
| US6312929B1 (en) * | 2000-12-22 | 2001-11-06 | Cepheid | Compositions and methods enabling a totally internally controlled amplification reaction |
| US6509186B1 (en) * | 2001-02-16 | 2003-01-21 | Institute Of Microelectronics | Miniaturized thermal cycler |
| US6432695B1 (en) * | 2001-02-16 | 2002-08-13 | Institute Of Microelectronics | Miniaturized thermal cycler |
| WO2002074898A2 (en) * | 2001-03-16 | 2002-09-26 | Techne (Cambridge) Ltd | Gradient block temperature control device |
| AU2002307152A1 (en) * | 2001-04-06 | 2002-10-21 | California Institute Of Technology | Nucleic acid amplification utilizing microfluidic devices |
| US6762049B2 (en) * | 2001-07-05 | 2004-07-13 | Institute Of Microelectronics | Miniaturized multi-chamber thermal cycler for independent thermal multiplexing |
| US6766817B2 (en) * | 2001-07-25 | 2004-07-27 | Tubarc Technologies, Llc | Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action |
| KR100450818B1 (ko) * | 2002-03-09 | 2004-10-01 | 삼성전자주식회사 | 다챔버 pcr 칩 |
| US6717365B2 (en) * | 2002-04-18 | 2004-04-06 | Lg Electronics Inc. | Magnetron |
| US6710442B1 (en) * | 2002-08-27 | 2004-03-23 | Micron Technology, Inc. | Microelectronic devices with improved heat dissipation and methods for cooling microelectronic devices |
| US6875602B2 (en) * | 2002-09-24 | 2005-04-05 | The United States Of America As Represented By The Secretary Of The Army | Portable thermocycler |
| AU2004243070B2 (en) * | 2003-05-23 | 2010-04-15 | Bio-Rad Laboratories, Inc. | Localized temperature control for spatial arrays of reaction media |
| US20060246573A1 (en) * | 2003-07-04 | 2006-11-02 | Kubota Corporation | Bio-chip |
-
2004
- 2004-05-20 AU AU2004243070A patent/AU2004243070B2/en not_active Ceased
- 2004-05-20 DE DE04752947T patent/DE04752947T1/de active Pending
- 2004-05-20 CA CA2523040A patent/CA2523040C/en not_active Expired - Fee Related
- 2004-05-20 JP JP2006533292A patent/JP4705035B2/ja not_active Expired - Lifetime
- 2004-05-20 EP EP04752947.4A patent/EP1641563B1/en not_active Expired - Lifetime
- 2004-05-20 WO PCT/US2004/016025 patent/WO2004105947A2/en not_active Ceased
- 2004-05-21 US US10/851,682 patent/US7771933B2/en active Active
-
2010
- 2010-01-05 US US12/652,611 patent/US8945881B2/en not_active Expired - Lifetime
-
2014
- 2014-12-11 US US14/567,121 patent/US9623414B2/en not_active Expired - Fee Related
-
2017
- 2017-03-09 US US15/454,910 patent/US20170239663A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050009070A1 (en) | 2005-01-13 |
| WO2004105947A2 (en) | 2004-12-09 |
| AU2004243070B2 (en) | 2010-04-15 |
| US8945881B2 (en) | 2015-02-03 |
| US7771933B2 (en) | 2010-08-10 |
| EP1641563A4 (en) | 2012-01-18 |
| US20100099581A1 (en) | 2010-04-22 |
| WO2004105947A3 (en) | 2005-12-22 |
| JP2007503217A (ja) | 2007-02-22 |
| US20150258547A1 (en) | 2015-09-17 |
| US20170239663A1 (en) | 2017-08-24 |
| EP1641563B1 (en) | 2018-08-29 |
| EP1641563A2 (en) | 2006-04-05 |
| US9623414B2 (en) | 2017-04-18 |
| CA2523040A1 (en) | 2004-12-09 |
| AU2004243070A1 (en) | 2004-12-09 |
| JP4705035B2 (ja) | 2011-06-22 |
| CA2523040C (en) | 2012-01-17 |
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