EP2027251A4 - Thermal cycling system - Google Patents

Thermal cycling system

Info

Publication number
EP2027251A4
EP2027251A4 EP07783905A EP07783905A EP2027251A4 EP 2027251 A4 EP2027251 A4 EP 2027251A4 EP 07783905 A EP07783905 A EP 07783905A EP 07783905 A EP07783905 A EP 07783905A EP 2027251 A4 EP2027251 A4 EP 2027251A4
Authority
EP
European Patent Office
Prior art keywords
thermal cycling
cycling system
thermal
cycling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07783905A
Other languages
German (de)
French (fr)
Other versions
EP2027251A2 (en
Inventor
George Maltezos
Matthew Johnston
David Goodwin
Axel Scherer
Christopher I Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Priority to EP12178744.4A priority Critical patent/EP2535427A3/en
Publication of EP2027251A2 publication Critical patent/EP2027251A2/en
Publication of EP2027251A4 publication Critical patent/EP2027251A4/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/02—Water baths; Sand baths; Air baths
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP07783905A 2006-05-17 2007-05-17 Thermal cycling system Ceased EP2027251A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12178744.4A EP2535427A3 (en) 2006-05-17 2007-05-17 Thermal cycling system

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US80117806P 2006-05-17 2006-05-17
US83249206P 2006-07-21 2006-07-21
US87308406P 2006-12-06 2006-12-06
US87317206P 2006-12-06 2006-12-06
PCT/US2007/069197 WO2008070198A2 (en) 2006-05-17 2007-05-17 Thermal cycling system

Publications (2)

Publication Number Publication Date
EP2027251A2 EP2027251A2 (en) 2009-02-25
EP2027251A4 true EP2027251A4 (en) 2010-05-05

Family

ID=39492885

Family Applications (2)

Application Number Title Priority Date Filing Date
EP12178744.4A Withdrawn EP2535427A3 (en) 2006-05-17 2007-05-17 Thermal cycling system
EP07783905A Ceased EP2027251A4 (en) 2006-05-17 2007-05-17 Thermal cycling system

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP12178744.4A Withdrawn EP2535427A3 (en) 2006-05-17 2007-05-17 Thermal cycling system

Country Status (3)

Country Link
EP (2) EP2535427A3 (en)
JP (1) JP2009537152A (en)
WO (1) WO2008070198A2 (en)

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CN102471746B (en) * 2009-08-20 2013-07-10 宝生物工程有限公司 Temperature cycling device
WO2011031377A1 (en) * 2009-09-09 2011-03-17 Helixis, Inc. Optical system for multiple reactions
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ES2363697B1 (en) * 2009-10-26 2012-04-20 Ingenia Biosystems, S.L. APPARATUS FOR LOCKING NUCLEIC ACIDS BY PHOTOACTIVATION OF INTERCALANT AGENTS.
CN102791847B (en) * 2010-01-12 2015-01-21 阿赫姆生物系统公司 Three-stage thermal convection apparatus and uses thereof
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
CN103003448B (en) * 2010-04-09 2015-06-17 生命技术公司 Improved thermal uniformity for thermal cycler instrumentation using dynamic control
US9170028B1 (en) 2010-10-06 2015-10-27 Lawrence Livermore National Security, Llc Methods and compositions for rapid thermal cycling
WO2012075360A1 (en) 2010-12-03 2012-06-07 Idaho Technology, Inc. Thermal cycler apparatus and related methods
JP5687514B2 (en) * 2011-02-17 2015-03-18 株式会社日立ハイテクノロジーズ Nucleic acid sequence analyzer
JP2012187054A (en) * 2011-03-11 2012-10-04 Hitachi High-Technologies Corp Nucleic acid amplification reaction apparatus
ES2617599T3 (en) * 2011-04-15 2017-06-19 Becton, Dickinson And Company Real-time scanning microfluidic thermocycler and methods for synchronized thermocycling and optical scanning detection
JP5663541B2 (en) * 2012-09-19 2015-02-04 株式会社日立ハイテクノロジーズ Reaction vessel, parallel processing device, and sequencer
US20140112829A1 (en) * 2012-10-22 2014-04-24 Qiagen Gaithersburg, Inc. Tube strip handling and heating apparatus
EP3549674B1 (en) 2012-12-21 2020-08-12 PerkinElmer Health Sciences, Inc. Low elasticity films for microfluidic use
JP2016509206A (en) 2012-12-21 2016-03-24 マイクロニクス， インコーポレイテッド Portable fluorescence detection system and microassay cartridge
US10065186B2 (en) 2012-12-21 2018-09-04 Micronics, Inc. Fluidic circuits and related manufacturing methods
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
AU2014262710B2 (en) 2013-05-07 2019-09-12 Perkinelmer Health Sciences, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
JP6484222B2 (en) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド Devices for nucleic acid preparation and analysis
US9352502B2 (en) 2013-06-25 2016-05-31 Lawrence Livermore National Security, Llc Porous media heat transfer for injection molding
US20160214110A1 (en) 2013-09-16 2016-07-28 Life Technologies Corporation Apparatuses, Systems and Methods for Providing Thermocycler Thermal Uniformity
KR20160123356A (en) 2014-02-18 2016-10-25 라이프 테크놀로지스 코포레이션 Apparatuses, systems and methods for providing scalable thermal cyclers and isolating thermoelectric devices
KR20210006337A (en) * 2018-03-15 2021-01-18 크립토스 바이오테크놀로지스, 인코포레이티드 Methods and systems for performing heat assisted biochemical reactions
CN109030133B (en) * 2018-06-14 2021-04-30 华东交通大学 Method for manufacturing test piece by using T-shaped sample
US11440015B2 (en) 2018-08-08 2022-09-13 Lawrence Livermore National Security, Llc Integrated solid-state rapid thermo-cycling system
CN109168298A (en) * 2018-10-18 2019-01-08 中国科学院合肥物质科学研究院 A kind of radiator for PCR detector temperature control system
US10993830B2 (en) 2018-11-09 2021-05-04 Dignitana Ab Scalp cooling apparatus, method, and system
SG10201908290RA (en) * 2019-09-09 2021-04-29 Star Array Pte Ltd Apparatus for polymerase chain reaction of nucleic acid
DE102022109312A1 (en) 2021-05-05 2022-11-10 Frieder Weidhase Device for accelerated, miniaturized cooling and heating in medical technology
CN114854570B (en) * 2022-07-05 2022-09-02 鲲鹏基因（北京）科技有限责任公司 Temperature control device, liquid cooling temperature control system and PCR instrument
WO2024123340A1 (en) * 2022-12-08 2024-06-13 Becton, Dickinson And Company FULLY AUTOMATED dPCR SYSTEMS AND METHODS OF USE THEREOF

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EP0363143A2 (en) * 1988-10-06 1990-04-11 Coy Corporation Temperature control apparatus
JPH07185363A (en) * 1993-12-27 1995-07-25 Shuji Ueda Heating and cooling device
US20020086417A1 (en) * 2000-12-29 2002-07-04 Shuqi Chen Sample processing device and method
US20030157721A1 (en) * 1998-08-13 2003-08-21 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
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EP0363143A2 (en) * 1988-10-06 1990-04-11 Coy Corporation Temperature control apparatus
JPH07185363A (en) * 1993-12-27 1995-07-25 Shuji Ueda Heating and cooling device
US20030157721A1 (en) * 1998-08-13 2003-08-21 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
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WO2004105947A2 (en) * 2003-05-23 2004-12-09 Bio-Rad Laboratories, Inc. Localized temperature control for spatial arrays of reaction media

Also Published As

Publication number Publication date
EP2535427A3 (en) 2013-04-24
EP2535427A2 (en) 2012-12-19
EP2027251A2 (en) 2009-02-25
WO2008070198A3 (en) 2009-04-16
WO2008070198A8 (en) 2008-12-24
JP2009537152A (en) 2009-10-29
WO2008070198A2 (en) 2008-06-12

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