DD299178A5 - 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel - Google Patents

24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel Download PDF

Info

Publication number
DD299178A5
DD299178A5 DD90344338A DD34433890A DD299178A5 DD 299178 A5 DD299178 A5 DD 299178A5 DD 90344338 A DD90344338 A DD 90344338A DD 34433890 A DD34433890 A DD 34433890A DD 299178 A5 DD299178 A5 DD 299178A5
Authority
DD
German Democratic Republic
Prior art keywords
homo
vitamin
compound
group
triol
Prior art date
Application number
DD90344338A
Other languages
German (de)
English (en)
Inventor
Gerald Dr Kirsch
Guenter Dr Neef
Katica Schwarz
Matthias Dr Braeutigam
Ruth Dr Thieroff-Eckerdt
Petra Rach
Original Assignee
�������@������������@��k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@������������@��k�� filed Critical �������@������������@��k��
Publication of DD299178A5 publication Critical patent/DD299178A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DD90344338A 1989-10-02 1990-10-01 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel DD299178A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3933034A DE3933034A1 (de) 1989-10-02 1989-10-02 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DD299178A5 true DD299178A5 (de) 1992-04-02

Family

ID=6390762

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90344338A DD299178A5 (de) 1989-10-02 1990-10-01 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel

Country Status (18)

Country Link
US (1) US5665716A (fr)
EP (1) EP0421561B1 (fr)
JP (1) JPH03246273A (fr)
CN (2) CN1031705C (fr)
AT (1) ATE103893T1 (fr)
AU (1) AU639717B2 (fr)
CA (1) CA2026671C (fr)
DD (1) DD299178A5 (fr)
DE (2) DE3933034A1 (fr)
DK (1) DK0421561T3 (fr)
ES (1) ES2052166T3 (fr)
FI (1) FI93643C (fr)
HU (1) HU210032B (fr)
IE (1) IE71227B1 (fr)
IL (1) IL95872A (fr)
NO (1) NO178923C (fr)
PT (1) PT95473B (fr)
ZA (1) ZA907876B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
DE4200783C2 (de) * 1992-01-10 1997-02-06 Schering Ag (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
DE19935771A1 (de) 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP2004504295A (ja) * 2000-07-18 2004-02-12 ボーン　ケア　インターナショナル　インコーポレイテッド 安定化１α−ヒドロキシビタミンＤ
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US8129173B2 (en) * 2002-01-10 2012-03-06 Teva Pharmaceutical Industries Ltd. Selective enzymatic esterification and solvolysis of epimeric vitamin D analog and separation of the epimers
EP1461314A1 (fr) * 2002-06-13 2004-09-29 Teva Pharmaceutical Industries Limited Epimerisation d'analogues de la vitamine d
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
MX2009002337A (es) * 2006-08-29 2009-03-20 Teva Pharma Composiciones farmacologicamente estables que incluyen compuestos que contienen vitamina d y corticosteroides con compatibilidad con bajo ph.
EP2299809B1 (fr) * 2008-06-17 2018-10-17 Ben Gurion University Of The Negev R&D Authority Composés de cyclohexylidène-éthylidène-octahydro-indène substitués
CN107019795A (zh) 2009-01-27 2017-08-08 博格有限责任公司 用于减轻与化疗有关的副作用的维生素d3化合物
MX366076B (es) 2009-08-14 2019-06-27 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
NZ714801A (en) 2013-05-29 2021-07-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
US10548908B2 (en) 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8520265A (nl) * 1984-10-04 1986-09-01 Wisconsin Alumni Res Found Derivaten van vitamine d en werkwijzen voor het bereiden daarvan.
EP0245524B1 (fr) * 1985-11-21 1991-04-17 Taisho Pharmaceutical Co. Ltd Derive de la vitamine d 3
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US4847012A (en) * 1988-04-29 1989-07-11 Wisconsin Alumni Research Foundation Vitamin D related compounds and processes for their preparation
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Also Published As

Publication number Publication date
IL95872A0 (en) 1991-07-18
FI93643B (fi) 1995-01-31
PT95473B (pt) 1997-07-31
ES2052166T3 (es) 1994-07-01
CN1106666A (zh) 1995-08-16
HUT55751A (en) 1991-06-28
DE3933034A1 (de) 1991-04-11
HU906284D0 (en) 1991-03-28
NO904269D0 (no) 1990-10-01
HU210032B (en) 1995-01-30
IE903520A1 (en) 1991-04-10
US5665716A (en) 1997-09-09
DE59005254D1 (de) 1994-05-11
CA2026671A1 (fr) 1991-04-03
AU639717B2 (en) 1993-08-05
ZA907876B (en) 1992-04-29
CN1031705C (zh) 1996-05-01
ATE103893T1 (de) 1994-04-15
NO904269L (no) 1991-04-03
CN1051907A (zh) 1991-06-05
EP0421561A3 (en) 1991-06-12
IL95872A (en) 1995-03-15
AU6371590A (en) 1991-04-11
EP0421561A2 (fr) 1991-04-10
EP0421561B1 (fr) 1994-04-06
CN1053103C (zh) 2000-06-07
PT95473A (pt) 1991-06-25
FI904850A0 (fi) 1990-10-02
DK0421561T3 (da) 1994-07-25
FI93643C (fi) 1995-05-10
IE71227B1 (en) 1997-02-12
NO178923B (no) 1996-03-25
JPH03246273A (ja) 1991-11-01
CA2026671C (fr) 1998-12-08
NO178923C (no) 1996-07-03

Similar Documents

Publication Publication Date Title
DD299178A5 (de) 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
DE68907483T2 (de) Vitamin d analoge.
EP0637299B1 (fr) Derives de vitamine d a substitution 20-methyle
CA1340614C (fr) Analogues de cyclopentano-vitamine d
EP0639179B1 (fr) Derives 23-oxa de vitamines de la serie d, procede de preparation desdits derives, preparation pharmaceutique contenant ces derives, et utilisation desdites preparations comme medicaments
DE69307871T2 (de) Neue vitamin-d analoge
EP0663902B1 (fr) Derives d'acide carboxylique 25 de la serie de la vitamine d, preparations pharmaceutiques contenant ces derives et leur utilisation pour preparer des medicaments
EP0832063B1 (fr) Derives de vitamine d comportant des substituants en c-25, leurs procedes de preparation, produits intermediaires et leur utilisation pour produire des medicaments
JPH04506965A (ja) 新規ビタミンｄ類似体
US5532228A (en) Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
WO1991015448A1 (fr) 24-oxa-derives de la serie de la vitamine d
EP0307786A2 (fr) Dérivés de cholécalciférol dentérés, leur préparation et leur utilisation en pharmacie
KR100202434B1 (ko) 26,27-디메틸렌-1알파,25-디히드록시비타민d₂및 26,27-디메틸렌-24-에피1알파,25-디히드록시비타민d₂, 및 이들의 제조방법
DE69307478T2 (de) Vitamin D3 Derivate
EP0441467B1 (fr) Homologues à chaîne latérale de vitamine D, procédé de leur préparation, compositions pharmaceutiques les contenant et leur utilisation comme médicament
EP0374219A1 (fr) HOMOLOGUES DE 1$g(a)-HYDROXYVITAMINE D INSATURES A CHAINE LATERALE
DE69732369T2 (de) Vitamin d3-derivate
EP1025082A1 (fr) Nouveaux derives de vitamine d comprenant des composes cycliques cyclopropyle dans les chaines laterales, procede et produits intermediaires permettant de les preparer, et leur utilisation pour preparer des medicaments
DE4003854A1 (de) Seitenketten-homologe vitamin d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
EP1219599B1 (fr) Derives de vitamine d ayant des substituants a la position 2 alpha
DE4234382A1 (de) 25-Carbonsäure-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
DE4034730A1 (de) Seitenketten-homologe vitamin-d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
DE4200783A1 (de) 24-benzyl-vitamin d-derivate

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee