DD284880A5 - Verfahren zum herstellen von penem-verbindungen - Google Patents

Verfahren zum herstellen von penem-verbindungen Download PDF

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Publication number
DD284880A5
DD284880A5 DD89333701A DD33370189A DD284880A5 DD 284880 A5 DD284880 A5 DD 284880A5 DD 89333701 A DD89333701 A DD 89333701A DD 33370189 A DD33370189 A DD 33370189A DD 284880 A5 DD284880 A5 DD 284880A5
Authority
DD
German Democratic Republic
Prior art keywords
compound
formula
solution
ethyl
methyl
Prior art date
Application number
DD89333701A
Other languages
German (de)
English (en)
Inventor
Nell Brian Th O
Douglas Phillips
Original Assignee
Pfizer Inc.,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc.,Us filed Critical Pfizer Inc.,Us
Publication of DD284880A5 publication Critical patent/DD284880A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD89333701A 1988-10-19 1989-10-18 Verfahren zum herstellen von penem-verbindungen DD284880A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/260,141 US4895940A (en) 1988-10-19 1988-10-19 Process for the preparation of penems

Publications (1)

Publication Number Publication Date
DD284880A5 true DD284880A5 (de) 1990-11-28

Family

ID=22987936

Family Applications (1)

Application Number Title Priority Date Filing Date
DD89333701A DD284880A5 (de) 1988-10-19 1989-10-18 Verfahren zum herstellen von penem-verbindungen

Country Status (6)

Country Link
US (1) US4895940A (es)
CS (1) CS274448B2 (es)
DD (1) DD284880A5 (es)
MX (1) MX18036A (es)
RU (1) RU2024528C1 (es)
ZA (1) ZA897883B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191075A (en) * 1988-10-19 1993-03-02 Pfizer Inc Process for the preparation of penems
US5258509A (en) * 1989-11-21 1993-11-02 Banyu Pharmaceutical Co., Ltd. Process for producing 2-carbon-substituted carbapenem derivatives

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5466695A (en) * 1977-11-08 1979-05-29 Sankyo Co Ltd Azetidinone derivative and its preparation
US4314942A (en) * 1979-01-10 1982-02-09 Schering Corporation Deprotection of allylic esters, carbonates and carbamates catalyzed by palladium compounds
US4443463A (en) * 1979-11-05 1984-04-17 Schering Corporation (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(hydroxyalkylthio)-penem-3-carboxylates
US4443373A (en) * 1982-03-30 1984-04-17 Schering Corporation Process for the production of antibiotic penems
US4530793A (en) * 1982-11-29 1985-07-23 Schering Corporation Processes for the production of penems
US4675317A (en) * 1983-01-25 1987-06-23 Merck & Co., Inc. 2-unsaturated alkylthio-pen-2-em-3-carboxylic acids
US4610823A (en) * 1983-01-25 1986-09-09 Merck & Co., Inc. Process for preparing substituted 2-thioxopenams and 2-substituted thiopenems
ZA841781B (en) * 1983-03-14 1985-07-31 Schering Corp Penim compounds,methods for their preparation and pharmaceutical compositions containing them
US4614738A (en) * 1983-03-25 1986-09-30 Schering Corporation 2-(N-heterocycloaliphaticthio)penems
US4619924A (en) * 1984-05-18 1986-10-28 Pfizer Inc. 2-alkylthiopenem derivatives
US4614737A (en) * 1983-10-14 1986-09-30 Pfizer Inc. 2-dioxacycloalkylthiopenem derivatives
US4584133A (en) * 1983-11-07 1986-04-22 Schering Corporation Process for the production of penems
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
US4769451A (en) * 1985-08-15 1988-09-06 Bristol-Myers Company Synthesis of carbapenems using n-substituted azetidinones
US4739047A (en) * 1985-10-17 1988-04-19 Pfizer Inc. Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
US4782145A (en) * 1986-06-02 1988-11-01 Pfizer Inc. Process for penem derivatives
GB2195627A (en) * 1986-08-12 1988-04-13 Hoechst Uk Ltd Penem derivatives
US4751297A (en) * 1987-03-20 1988-06-14 Pfizer Inc. Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate

Also Published As

Publication number Publication date
CS274448B2 (en) 1991-04-11
US4895940A (en) 1990-01-23
MX18036A (es) 1993-05-01
CS590789A2 (en) 1990-08-14
ZA897883B (en) 1991-06-26
RU2024528C1 (ru) 1994-12-15

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Legal Events

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ENJ Ceased due to non-payment of renewal fee