ZA897883B - Process for the preparation of penems - Google Patents

Process for the preparation of penems

Info

Publication number
ZA897883B
ZA897883B ZA897883A ZA897883A ZA897883B ZA 897883 B ZA897883 B ZA 897883B ZA 897883 A ZA897883 A ZA 897883A ZA 897883 A ZA897883 A ZA 897883A ZA 897883 B ZA897883 B ZA 897883B
Authority
ZA
South Africa
Prior art keywords
penems
preparation
Prior art date
Application number
ZA897883A
Other languages
English (en)
Inventor
Brain Thomas O'neill
Thomas O'neill Brain
Douglas Phillips
Phillips Douglas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA897883B publication Critical patent/ZA897883B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA897883A 1988-10-19 1989-10-18 Process for the preparation of penems ZA897883B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/260,141 US4895940A (en) 1988-10-19 1988-10-19 Process for the preparation of penems

Publications (1)

Publication Number Publication Date
ZA897883B true ZA897883B (en) 1991-06-26

Family

ID=22987936

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897883A ZA897883B (en) 1988-10-19 1989-10-18 Process for the preparation of penems

Country Status (6)

Country Link
US (1) US4895940A (xx)
CS (1) CS274448B2 (xx)
DD (1) DD284880A5 (xx)
MX (1) MX18036A (xx)
RU (1) RU2024528C1 (xx)
ZA (1) ZA897883B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191075A (en) * 1988-10-19 1993-03-02 Pfizer Inc Process for the preparation of penems
US5258509A (en) * 1989-11-21 1993-11-02 Banyu Pharmaceutical Co., Ltd. Process for producing 2-carbon-substituted carbapenem derivatives

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5466695A (en) * 1977-11-08 1979-05-29 Sankyo Co Ltd Azetidinone derivative and its preparation
US4314942A (en) * 1979-01-10 1982-02-09 Schering Corporation Deprotection of allylic esters, carbonates and carbamates catalyzed by palladium compounds
US4443463A (en) * 1979-11-05 1984-04-17 Schering Corporation (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(hydroxyalkylthio)-penem-3-carboxylates
US4443373A (en) * 1982-03-30 1984-04-17 Schering Corporation Process for the production of antibiotic penems
US4530793A (en) * 1982-11-29 1985-07-23 Schering Corporation Processes for the production of penems
US4610823A (en) * 1983-01-25 1986-09-09 Merck & Co., Inc. Process for preparing substituted 2-thioxopenams and 2-substituted thiopenems
US4675317A (en) * 1983-01-25 1987-06-23 Merck & Co., Inc. 2-unsaturated alkylthio-pen-2-em-3-carboxylic acids
ZA841781B (en) * 1983-03-14 1985-07-31 Schering Corp Penim compounds,methods for their preparation and pharmaceutical compositions containing them
US4614738A (en) * 1983-03-25 1986-09-30 Schering Corporation 2-(N-heterocycloaliphaticthio)penems
US4619924A (en) * 1984-05-18 1986-10-28 Pfizer Inc. 2-alkylthiopenem derivatives
US4614737A (en) * 1983-10-14 1986-09-30 Pfizer Inc. 2-dioxacycloalkylthiopenem derivatives
US4584133A (en) * 1983-11-07 1986-04-22 Schering Corporation Process for the production of penems
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
US4769451A (en) * 1985-08-15 1988-09-06 Bristol-Myers Company Synthesis of carbapenems using n-substituted azetidinones
US4739047A (en) * 1985-10-17 1988-04-19 Pfizer Inc. Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
US4782145A (en) * 1986-06-02 1988-11-01 Pfizer Inc. Process for penem derivatives
GB2195627A (en) * 1986-08-12 1988-04-13 Hoechst Uk Ltd Penem derivatives
US4751297A (en) * 1987-03-20 1988-06-14 Pfizer Inc. Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate

Also Published As

Publication number Publication date
DD284880A5 (de) 1990-11-28
MX18036A (es) 1993-05-01
CS590789A2 (en) 1990-08-14
US4895940A (en) 1990-01-23
CS274448B2 (en) 1991-04-11
RU2024528C1 (ru) 1994-12-15

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