BG51041A3 - Process for the preparation of (s)- alpha- ethyl- 2- oxo- 1- pyrrolidineacetamide - Google Patents
Process for the preparation of (s)- alpha- ethyl- 2- oxo- 1- pyrrolidineacetamideInfo
- Publication number
- BG51041A3 BG51041A3 BG90398A BG9039889A BG51041A3 BG 51041 A3 BG51041 A3 BG 51041A3 BG 90398 A BG90398 A BG 90398A BG 9039889 A BG9039889 A BG 9039889A BG 51041 A3 BG51041 A3 BG 51041A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- pyrrolidineacetamide
- oxo
- alpha
- ethyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888827389A GB8827389D0 (en) | 1988-11-23 | 1988-11-23 | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
Publications (1)
Publication Number | Publication Date |
---|---|
BG51041A3 true BG51041A3 (en) | 1993-01-15 |
Family
ID=10647345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG90398A BG51041A3 (en) | 1988-11-23 | 1989-11-20 | Process for the preparation of (s)- alpha- ethyl- 2- oxo- 1- pyrrolidineacetamide |
Country Status (17)
Country | Link |
---|---|
KR (1) | KR0157610B1 (en) |
CN (1) | CN1020604C (en) |
AT (1) | AT392781B (en) |
BG (1) | BG51041A3 (en) |
CY (1) | CY1672A (en) |
ES (1) | ES2023532A6 (en) |
FI (1) | FI91961C (en) |
GB (2) | GB8827389D0 (en) |
GR (1) | GR1000719B (en) |
HK (1) | HK102492A (en) |
HU (1) | HU204508B (en) |
NO (1) | NO173823C (en) |
PH (1) | PH26332A (en) |
PL (1) | PL161781B1 (en) |
PT (1) | PT92365B (en) |
RU (1) | RU1797607C (en) |
SG (1) | SG89392G (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9319732D0 (en) | 1993-09-24 | 1993-11-10 | Ucb Sa | Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety |
US6107492A (en) * | 1998-05-08 | 2000-08-22 | Ucb, S.A. | Process for the preparation of levetiracetam |
CZ20021904A3 (en) | 1999-12-01 | 2002-11-13 | Ucb, S. A. | Pyrrolidine acetamide derivative per se or in combination used for treating central nervous system disorders |
GB0004297D0 (en) | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
WO2004069796A2 (en) * | 2003-02-03 | 2004-08-19 | Teva Pharmaceutical Industries Ltd. | Process for producing levetiracetam |
ES2214147B1 (en) * | 2003-02-28 | 2005-10-01 | Farma-Lepori S.A. | PROCEDURE FOR OBTAINING AN ANTIEPILEPTIC AGENT. |
KR101124098B1 (en) | 2003-09-24 | 2012-03-21 | 유씨비 파마, 에스.에이. | Process for preparing 2-oxo-1-pyrrolidine derivatives |
CA2488325C (en) | 2004-11-22 | 2010-08-24 | Apotex Pharmachem Inc. | Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
ES2441178T3 (en) | 2005-06-01 | 2014-02-03 | Ucb Pharma, S.A. | 2-Oxo-1-pyrrolidine derivatives, procedures to prepare them and their therapeutic use on the central nervous system |
US8338621B2 (en) | 2005-12-21 | 2012-12-25 | Ucb S.A. | Process for the preparation of 2-oxo-1-pyrrolidine derivatives |
WO2009050735A1 (en) * | 2007-10-15 | 2009-04-23 | Lupin Limited | A novel polymorph of levetiracetam and a process for its preparation |
EP2147911A1 (en) | 2008-07-24 | 2010-01-27 | ZaCh System S.p.A. | Process for the preparation of levetiracetam |
US7939676B2 (en) | 2009-09-17 | 2011-05-10 | Zach System S.P.A. | Process for the preparation of levetiracetam |
CN109999025A (en) | 2014-01-21 | 2019-07-12 | 詹森药业有限公司 | Positive allosteric modulator or the combination of normotopia agonist including metabotropic glutamate energy receptor subtype 2 and application thereof |
NZ722385A (en) | 2014-01-21 | 2019-11-29 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1309692A (en) * | 1970-02-13 | 1973-03-14 | Ucb Sa | N-substituted lactams |
GB8412358D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
GB8412357D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
-
1988
- 1988-11-23 GB GB888827389A patent/GB8827389D0/en active Pending
-
1989
- 1989-11-20 GR GR890100769A patent/GR1000719B/en not_active IP Right Cessation
- 1989-11-20 BG BG90398A patent/BG51041A3/en unknown
- 1989-11-21 PT PT92365A patent/PT92365B/en not_active IP Right Cessation
- 1989-11-21 GB GB8926244A patent/GB2225322B/en not_active Expired - Lifetime
- 1989-11-22 PL PL89282413A patent/PL161781B1/en unknown
- 1989-11-22 AT AT2666/89A patent/AT392781B/en not_active IP Right Cessation
- 1989-11-22 CN CN89108764A patent/CN1020604C/en not_active Expired - Fee Related
- 1989-11-22 ES ES8903978A patent/ES2023532A6/en not_active Expired - Lifetime
- 1989-11-22 FI FI895562A patent/FI91961C/en active IP Right Grant
- 1989-11-22 RU SU4742434A patent/RU1797607C/en active
- 1989-11-22 HU HU896132A patent/HU204508B/en not_active IP Right Cessation
- 1989-11-22 NO NO894649A patent/NO173823C/en unknown
- 1989-11-23 KR KR1019890017038A patent/KR0157610B1/en not_active IP Right Cessation
- 1989-11-23 PH PH39568A patent/PH26332A/en unknown
-
1992
- 1992-09-05 SG SG893/92A patent/SG89392G/en unknown
- 1992-12-17 HK HK1024/92A patent/HK102492A/en not_active IP Right Cessation
-
1993
- 1993-05-14 CY CY1672A patent/CY1672A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2023532A6 (en) | 1992-01-16 |
HK102492A (en) | 1992-12-24 |
FI91961C (en) | 1994-09-12 |
HU204508B (en) | 1992-01-28 |
SG89392G (en) | 1992-12-04 |
GB2225322B (en) | 1992-03-25 |
HU896132D0 (en) | 1990-02-28 |
RU1797607C (en) | 1993-02-23 |
PH26332A (en) | 1992-04-29 |
NO894649L (en) | 1990-05-25 |
FI91961B (en) | 1994-05-31 |
PT92365B (en) | 1995-07-18 |
CN1042904A (en) | 1990-06-13 |
HUT53072A (en) | 1990-09-28 |
CN1020604C (en) | 1993-05-12 |
GB8827389D0 (en) | 1988-12-29 |
GB8926244D0 (en) | 1990-01-10 |
KR0157610B1 (en) | 1998-11-16 |
NO894649D0 (en) | 1989-11-22 |
FI895562A0 (en) | 1989-11-22 |
NO173823B (en) | 1993-11-01 |
GR890100769A (en) | 1990-12-31 |
PL161781B1 (en) | 1993-07-30 |
GB2225322A (en) | 1990-05-30 |
GR1000719B (en) | 1992-11-23 |
AT392781B (en) | 1991-06-10 |
ATA266689A (en) | 1990-11-15 |
KR900007797A (en) | 1990-06-02 |
CY1672A (en) | 1993-05-14 |
PT92365A (en) | 1990-05-31 |
NO173823C (en) | 1994-02-09 |
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