DD274033A5 - Verfahren zur herstellung von peptiden und peptidamiden - Google Patents

Verfahren zur herstellung von peptiden und peptidamiden Download PDF

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Publication number
DD274033A5
DD274033A5 DD88314098A DD31409888A DD274033A5 DD 274033 A5 DD274033 A5 DD 274033A5 DD 88314098 A DD88314098 A DD 88314098A DD 31409888 A DD31409888 A DD 31409888A DD 274033 A5 DD274033 A5 DD 274033A5
Authority
DD
German Democratic Republic
Prior art keywords
group
resin
groups
formula
amino
Prior art date
Application number
DD88314098A
Other languages
German (de)
English (en)
Inventor
Hans Rink
Original Assignee
����`��@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD274033A5 publication Critical patent/DD274033A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/50—Partial depolymerisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dental Preparations (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glass Compositions (AREA)
  • Polyamides (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Working-Up Tar And Pitch (AREA)
  • Paper (AREA)
DD88314098A 1987-03-30 1988-03-28 Verfahren zur herstellung von peptiden und peptidamiden DD274033A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH121487 1987-03-30

Publications (1)

Publication Number Publication Date
DD274033A5 true DD274033A5 (de) 1989-12-06

Family

ID=4205167

Family Applications (3)

Application Number Title Priority Date Filing Date
DD88314098A DD274033A5 (de) 1987-03-30 1988-03-28 Verfahren zur herstellung von peptiden und peptidamiden
DD88331994A DD284031A5 (de) 1987-03-30 1988-03-28 Verfahren zur herstellung eines kunstharzes
DD88331996A DD296087A5 (de) 1987-03-30 1988-03-28 Verfahren zur herstellung eines kunstharzes

Family Applications After (2)

Application Number Title Priority Date Filing Date
DD88331994A DD284031A5 (de) 1987-03-30 1988-03-28 Verfahren zur herstellung eines kunstharzes
DD88331996A DD296087A5 (de) 1987-03-30 1988-03-28 Verfahren zur herstellung eines kunstharzes

Country Status (19)

Country Link
US (3) US4859736A (es)
EP (1) EP0285562B1 (es)
JP (1) JP2513775B2 (es)
KR (1) KR950013679B1 (es)
AT (1) ATE88726T1 (es)
AU (1) AU615181B2 (es)
CA (1) CA1318462C (es)
DD (3) DD274033A5 (es)
DE (1) DE3880541D1 (es)
DK (1) DK175042B1 (es)
ES (1) ES2054863T3 (es)
FI (1) FI90780C (es)
GR (1) GR3007996T3 (es)
HU (1) HU208155B (es)
IE (1) IE61485B1 (es)
IL (1) IL85884A (es)
MX (1) MX10917A (es)
PT (1) PT87105B (es)
YU (1) YU62588A (es)

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GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis
US5242974A (en) * 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5212288A (en) * 1990-02-20 1993-05-18 Syntex (U.S.A.) Inc. Temporary minimal protection synthesis of serine-containing polypeptides
US5155166A (en) * 1990-06-18 1992-10-13 Eastman Kodak Company Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to carboxylated particles and a kit containing same
US5071565A (en) * 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
US5550215A (en) * 1991-11-22 1996-08-27 Holmes; Christopher P. Polymer reversal on solid surfaces
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
US5516891A (en) * 1992-06-16 1996-05-14 Kinerton, Ltd. Liquid phase synthesis of peptides and peptide derivatives
IE921942A1 (en) * 1992-06-16 1993-12-29 Gary A Siwruk John S Eynon Liquid phase synthesis of peptides and peptide derivatives
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
IL129728A0 (en) * 1996-11-04 2000-02-29 Dimensional Pharm Inc System method and computer program product for the visualization and interactive processing and analysis of chemical data
US6453246B1 (en) 1996-11-04 2002-09-17 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for representing proximity data in a multi-dimensional space
US6571227B1 (en) * 1996-11-04 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Method, system and computer program product for non-linear mapping of multi-dimensional data
US6392010B1 (en) 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
GB9717173D0 (en) 1997-08-13 1997-10-22 Akzo Nobel Nv Solid phase supports
US6114468A (en) * 1998-06-01 2000-09-05 Novartis Ag Synthetic resins for use in solid phase synthesis
US7416524B1 (en) 2000-02-18 2008-08-26 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. System, method and computer program product for fast and efficient searching of large chemical libraries
US6671627B2 (en) 2000-02-29 2003-12-30 3-D Pharmaceuticals, Inc. Method and computer program product for designing combinatorial arrays
US7039621B2 (en) 2000-03-22 2006-05-02 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. System, method, and computer program product for representing object relationships in a multidimensional space
AU2001249805A1 (en) 2000-04-03 2001-10-15 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for representing object relationships in a multidimensional space
CA2419600A1 (en) * 2000-08-22 2002-02-28 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for determining properties of combinatorial library products from features of library building blocks
AU2001292740A1 (en) * 2000-09-20 2002-04-02 Dimitris K. Agrafiotis Method, system, and computer program product for encoding and building products of a virtual combinatorial library
WO2002061419A1 (en) * 2001-01-29 2002-08-08 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for analyzing combinatorial libraries
WO2002083606A1 (en) * 2001-04-17 2002-10-24 University Of Alberta A linker system for the synthesis and screening of combinatorial libraries of polyamine derivatives on water compatible supports
US7119145B2 (en) * 2002-01-25 2006-10-10 Phenomenex, Inc. Surface graft modified resins and formation thereof
US6926823B2 (en) * 2002-06-03 2005-08-09 Varian, Inc. Polymer with superior polar retention for sample pretreatment
ATE501164T1 (de) * 2003-07-04 2011-03-15 Lonza Ag Verbessertes verfahren für festphasensynthese
EP1630600A3 (en) * 2004-07-29 2006-03-22 Rohm and Haas Electronic Materials, L.L.C. Hot melt composition and method involving forming a masking pattern
WO2006060803A2 (en) * 2004-12-03 2006-06-08 Polnox Corporation One pot process for making polymeric antioxidants
CA2761265C (en) * 2009-05-06 2017-12-19 Mallinckrodt Llc Solid support for fmoc-solid phase synthesis of peptide acids
TWI640541B (zh) 2011-12-28 2018-11-11 中外製藥股份有限公司 Peptide compound having an annular portion and pharmaceutical composition thereof
EP3071544B1 (en) 2013-11-22 2022-07-06 Polnox Corporation Macromolecular antioxidants based on dual type moiety per molecule: structures methods of making and using the same
US20180251695A1 (en) 2017-03-01 2018-09-06 Polnox Corporation Macromolecular Corrosion (McIn) Inhibitors: Structures, Methods Of Making And Using The Same
EP3636656A4 (en) 2017-06-09 2021-04-14 Chugai Seiyaku Kabushiki Kaisha PROCESS FOR SYNTHESIS OF A PEPTIDE CONTAINING AN N-SUBSTITUTED AMINO ACID
JP7411414B2 (ja) 2017-12-15 2024-01-11 中外製薬株式会社 ペプチドの製造方法、及び塩基の処理方法
WO2020111238A1 (ja) 2018-11-30 2020-06-04 中外製薬株式会社 ペプチド化合物、またはアミド化合物の脱保護法および固相反応における脱樹脂方法、並びにペプチド化合物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE141977C (es) *
GB1406611A (en) * 1971-08-17 1975-09-17 Leo Ab Pharmaceutically active secondary phosphoric acid esters
DD141977A3 (de) * 1975-07-11 1980-06-04 Jens Fischer Verfahren zur herstellung wasserunloeslicher enzym-polystyrol-komplexe
US4301045A (en) * 1977-05-02 1981-11-17 Armour Pharmaceutical Company Synthesis of peptides
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US4569967A (en) * 1983-10-24 1986-02-11 The Salk Institute For Biological Studies Synthesis of N-substituted peptide amides
US4623484A (en) * 1984-05-24 1986-11-18 Research Corporation Process for peptide synthesis
GB2169901A (en) * 1984-12-11 1986-07-23 Lkb Biochrom Ltd method for a solid phase synthesis of a linear combination of amino acid residues.
US4731412A (en) * 1984-12-28 1988-03-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptide esters
US4716147A (en) * 1986-03-27 1987-12-29 Monsanto Company Synthetic airial peptides
CA1329124C (en) * 1987-02-02 1994-05-03 Jerald C. Sadoff Conjugate malaria vaccine
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis

Also Published As

Publication number Publication date
EP0285562A2 (de) 1988-10-05
YU62588A (en) 1990-10-31
US5004781A (en) 1991-04-02
FI90780B (fi) 1993-12-15
KR950013679B1 (ko) 1995-11-13
DK175042B1 (da) 2004-05-10
CA1318462C (en) 1993-05-25
DD284031A5 (de) 1990-10-31
JPS63260946A (ja) 1988-10-27
KR880011210A (ko) 1988-10-27
MX10917A (es) 1993-12-01
US5093530A (en) 1992-03-03
US4859736A (en) 1989-08-22
ATE88726T1 (de) 1993-05-15
DD296087A5 (de) 1991-11-21
DE3880541D1 (de) 1993-06-03
HU208155B (en) 1993-08-30
IE61485B1 (en) 1994-11-02
DK173088D0 (da) 1988-03-29
IE880940L (en) 1988-09-30
IL85884A (en) 1992-01-15
HUT46713A (en) 1988-11-28
FI881451A (fi) 1988-10-01
DK173088A (da) 1988-10-01
PT87105B (pt) 1992-07-31
AU615181B2 (en) 1991-09-26
AU1381488A (en) 1988-09-29
FI881451A0 (fi) 1988-03-28
GR3007996T3 (es) 1993-08-31
FI90780C (fi) 1994-03-25
JP2513775B2 (ja) 1996-07-03
EP0285562B1 (de) 1993-04-28
ES2054863T3 (es) 1994-08-16
PT87105A (pt) 1988-04-01
EP0285562A3 (en) 1990-01-10

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