DD236927A5 - Verfahren zur herstellung von 2-amino-3-ethyoxy-carbonylamino-6-(p-fluor-benzylamino)-pyridin-gluconat - Google Patents
Verfahren zur herstellung von 2-amino-3-ethyoxy-carbonylamino-6-(p-fluor-benzylamino)-pyridin-gluconat Download PDFInfo
- Publication number
- DD236927A5 DD236927A5 DD85275890A DD27589085A DD236927A5 DD 236927 A5 DD236927 A5 DD 236927A5 DD 85275890 A DD85275890 A DD 85275890A DD 27589085 A DD27589085 A DD 27589085A DD 236927 A5 DD236927 A5 DD 236927A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- amino
- pyridine
- ethoxycarbonylamino
- benzylamino
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/10—Polyhydroxy carboxylic acids
- C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843416609 DE3416609A1 (de) | 1984-05-05 | 1984-05-05 | 2-amino-3-ethoxycarbonylamino-6-(p-fluor-benzylamino)- pyridin-gluconat und pharmazeutische zubereitungen, die diese substanz enthalten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD236927A5 true DD236927A5 (de) | 1986-06-25 |
Family
ID=6235001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD85275890A DD236927A5 (de) | 1984-05-05 | 1985-05-02 | Verfahren zur herstellung von 2-amino-3-ethyoxy-carbonylamino-6-(p-fluor-benzylamino)-pyridin-gluconat |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4673666A (ja) |
| EP (1) | EP0160865B1 (ja) |
| JP (1) | JPS60239469A (ja) |
| KR (1) | KR850008678A (ja) |
| AT (1) | ATE33638T1 (ja) |
| AU (1) | AU4194385A (ja) |
| BG (1) | BG44537A3 (ja) |
| CA (1) | CA1263398A (ja) |
| CS (1) | CS248743B2 (ja) |
| DD (1) | DD236927A5 (ja) |
| DE (2) | DE3416609A1 (ja) |
| DK (1) | DK157016C (ja) |
| ES (1) | ES8603423A1 (ja) |
| FI (1) | FI80443C (ja) |
| GR (1) | GR851065B (ja) |
| HU (1) | HU193753B (ja) |
| IE (1) | IE57766B1 (ja) |
| IL (1) | IL75086A (ja) |
| MC (1) | MC1651A1 (ja) |
| NO (1) | NO851772L (ja) |
| PL (1) | PL253202A1 (ja) |
| PT (1) | PT80386B (ja) |
| SU (1) | SU1398772A3 (ja) |
| YU (1) | YU71785A (ja) |
| ZA (1) | ZA853351B (ja) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6117432A (en) * | 1995-04-20 | 2000-09-12 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
| US6689370B1 (en) | 1995-04-20 | 2004-02-10 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
| FR2733151B1 (fr) * | 1995-04-20 | 1997-05-23 | Seppic Sa | Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines |
| US6821995B1 (en) | 1999-12-01 | 2004-11-23 | Duke University | Method of treating batten disease |
| DE10327674A1 (de) * | 2003-06-20 | 2005-01-05 | Awd.Pharma Gmbh & Co. Kg | Injizierbare Darreichungsform von Flupirtin |
| US20080279930A1 (en) * | 2007-05-07 | 2008-11-13 | Bernd Terhaag | Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof |
| EP2350009B1 (en) * | 2008-06-09 | 2016-03-16 | TEVA GmbH | Sulfonate salts of flupirtine |
| US8183267B2 (en) | 2008-06-09 | 2012-05-22 | Awd. Pharma Gmbh & Co. Kg | Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine |
| DE102010030053A1 (de) | 2010-06-14 | 2011-12-15 | Awd.Pharma Gmbh & Co.Kg | Injizierbare Darreichungsform von Flupirtin |
| WO2012004391A1 (en) | 2010-07-09 | 2012-01-12 | K.H.S. Pharma Holding Gmbh | Process for the preparation of flupirtine maleate |
| CN102850265B (zh) * | 2011-06-29 | 2015-11-25 | 陈小花 | 一种氟吡汀偶联物及其制备方法和用途 |
| CN102351786A (zh) * | 2011-11-01 | 2012-02-15 | 东南大学 | 一种氟吡汀丙二酸盐及其制备方法 |
| CN103910674B (zh) * | 2013-12-19 | 2015-12-02 | 天津红日药业股份有限公司 | 用于马来酸氟吡汀分析中的参比化合物 |
| CN104974087A (zh) * | 2015-01-30 | 2015-10-14 | 吉林修正药业新药开发有限公司 | 一种氟吡汀二聚体的合成方法 |
| DE102017007385A1 (de) | 2017-08-02 | 2019-02-07 | Christoph Hoock | Maleatfreie feste Arzneimittelformen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3133519A1 (de) * | 1980-09-13 | 1982-06-09 | Degussa Ag, 6000 Frankfurt | "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat" |
| US4481205A (en) * | 1980-09-13 | 1984-11-06 | Degussa Aktiengesellschaft | 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate |
-
1984
- 1984-05-05 DE DE19843416609 patent/DE3416609A1/de not_active Withdrawn
-
1985
- 1985-04-19 AT AT85104746T patent/ATE33638T1/de not_active IP Right Cessation
- 1985-04-19 EP EP85104746A patent/EP0160865B1/de not_active Expired
- 1985-04-19 DE DE8585104746T patent/DE3562242D1/de not_active Expired
- 1985-04-26 SU SU853884101A patent/SU1398772A3/ru active
- 1985-04-29 YU YU00717/85A patent/YU71785A/xx unknown
- 1985-04-30 CS CS853157A patent/CS248743B2/cs unknown
- 1985-05-01 US US06/729,413 patent/US4673666A/en not_active Expired - Lifetime
- 1985-05-02 GR GR851065A patent/GR851065B/el unknown
- 1985-05-02 DD DD85275890A patent/DD236927A5/de unknown
- 1985-05-02 DK DK198785A patent/DK157016C/da not_active IP Right Cessation
- 1985-05-03 AU AU41943/85A patent/AU4194385A/en not_active Abandoned
- 1985-05-03 HU HU851691A patent/HU193753B/hu unknown
- 1985-05-03 CA CA000480723A patent/CA1263398A/en not_active Expired
- 1985-05-03 NO NO851772A patent/NO851772L/no unknown
- 1985-05-03 BG BG070073A patent/BG44537A3/xx unknown
- 1985-05-03 ZA ZA853351A patent/ZA853351B/xx unknown
- 1985-05-03 PL PL25320285A patent/PL253202A1/xx unknown
- 1985-05-03 PT PT80386A patent/PT80386B/pt unknown
- 1985-05-03 IL IL75086A patent/IL75086A/xx unknown
- 1985-05-03 ES ES542817A patent/ES8603423A1/es not_active Expired
- 1985-05-03 IE IE1117/85A patent/IE57766B1/en not_active IP Right Cessation
- 1985-05-03 MC MC851765A patent/MC1651A1/xx unknown
- 1985-05-03 FI FI851752A patent/FI80443C/fi not_active IP Right Cessation
- 1985-05-04 KR KR1019850003047A patent/KR850008678A/ko not_active Application Discontinuation
- 1985-05-07 JP JP60095714A patent/JPS60239469A/ja active Granted
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