BG44537A3 - Method for preparing of 2- amino- 3- ethoxycarbonylamino- 6- (p- fluor- benzylamino)- piridine gluconate - Google Patents

Method for preparing of 2- amino- 3- ethoxycarbonylamino- 6- (p- fluor- benzylamino)- piridine gluconate

Info

Publication number
BG44537A3
BG44537A3 BG8570073A BG7007385A BG44537A3 BG 44537 A3 BG44537 A3 BG 44537A3 BG 8570073 A BG8570073 A BG 8570073A BG 7007385 A BG7007385 A BG 7007385A BG 44537 A3 BG44537 A3 BG 44537A3
Authority
BG
Bulgaria
Prior art keywords
ethoxycarbonylamino
benzylamino
amino
gluconate
piridine
Prior art date
Application number
BG8570073A
Other languages
English (en)
Inventor
Helmut Hettche
Peter Emig
Juergen Engel
Original Assignee
Degussa Ag,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa Ag,De filed Critical Degussa Ag,De
Publication of BG44537A3 publication Critical patent/BG44537A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10Polyhydroxy carboxylic acids
    • C07C59/105Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG8570073A 1984-05-05 1985-05-03 Method for preparing of 2- amino- 3- ethoxycarbonylamino- 6- (p- fluor- benzylamino)- piridine gluconate BG44537A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843416609 DE3416609A1 (de) 1984-05-05 1984-05-05 2-amino-3-ethoxycarbonylamino-6-(p-fluor-benzylamino)- pyridin-gluconat und pharmazeutische zubereitungen, die diese substanz enthalten

Publications (1)

Publication Number Publication Date
BG44537A3 true BG44537A3 (en) 1988-12-15

Family

ID=6235001

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8570073A BG44537A3 (en) 1984-05-05 1985-05-03 Method for preparing of 2- amino- 3- ethoxycarbonylamino- 6- (p- fluor- benzylamino)- piridine gluconate

Country Status (25)

Country Link
US (1) US4673666A (xx)
EP (1) EP0160865B1 (xx)
JP (1) JPS60239469A (xx)
KR (1) KR850008678A (xx)
AT (1) ATE33638T1 (xx)
AU (1) AU4194385A (xx)
BG (1) BG44537A3 (xx)
CA (1) CA1263398A (xx)
CS (1) CS248743B2 (xx)
DD (1) DD236927A5 (xx)
DE (2) DE3416609A1 (xx)
DK (1) DK157016C (xx)
ES (1) ES542817A0 (xx)
FI (1) FI80443C (xx)
GR (1) GR851065B (xx)
HU (1) HU193753B (xx)
IE (1) IE57766B1 (xx)
IL (1) IL75086A (xx)
MC (1) MC1651A1 (xx)
NO (1) NO851772L (xx)
PL (1) PL253202A1 (xx)
PT (1) PT80386B (xx)
SU (1) SU1398772A3 (xx)
YU (1) YU71785A (xx)
ZA (1) ZA853351B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2733151B1 (fr) * 1995-04-20 1997-05-23 Seppic Sa Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines
US6689370B1 (en) 1995-04-20 2004-02-10 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US6117432A (en) * 1995-04-20 2000-09-12 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
DE10327674A1 (de) * 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
EP2346826A2 (en) 2008-06-09 2011-07-27 AWD.pharma GmbH & Co.KG Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine
WO2009152142A1 (en) * 2008-06-09 2009-12-17 Awd. Pharma Gmbh & Co. Kg Sulfonate salts of flupirtine
DE102010030053A1 (de) * 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
WO2012004391A1 (en) 2010-07-09 2012-01-12 K.H.S. Pharma Holding Gmbh Process for the preparation of flupirtine maleate
CN102850265B (zh) * 2011-06-29 2015-11-25 陈小花 一种氟吡汀偶联物及其制备方法和用途
CN102351786A (zh) * 2011-11-01 2012-02-15 东南大学 一种氟吡汀丙二酸盐及其制备方法
CN103910674B (zh) * 2013-12-19 2015-12-02 天津红日药业股份有限公司 用于马来酸氟吡汀分析中的参比化合物
CN104974087A (zh) * 2015-01-30 2015-10-14 吉林修正药业新药开发有限公司 一种氟吡汀二聚体的合成方法
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481205A (en) * 1980-09-13 1984-11-06 Degussa Aktiengesellschaft 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate
DE3133519A1 (de) * 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat"

Also Published As

Publication number Publication date
HU193753B (en) 1987-11-30
PT80386B (de) 1987-04-16
ES8603423A1 (es) 1985-12-16
FI80443B (fi) 1990-02-28
DK157016B (da) 1989-10-30
ES542817A0 (es) 1985-12-16
NO851772L (no) 1985-11-06
AU4194385A (en) 1985-11-07
MC1651A1 (fr) 1986-04-07
JPH0144185B2 (xx) 1989-09-26
IL75086A (en) 1988-03-31
FI80443C (fi) 1990-06-11
PL253202A1 (en) 1986-07-15
ZA853351B (en) 1985-12-24
US4673666A (en) 1987-06-16
HUT37758A (en) 1986-02-28
DD236927A5 (de) 1986-06-25
CA1263398A (en) 1989-11-28
YU71785A (en) 1988-02-29
IE851117L (en) 1985-11-05
DK157016C (da) 1990-03-26
ATE33638T1 (de) 1988-05-15
DE3416609A1 (de) 1985-11-07
IL75086A0 (en) 1985-09-29
CS248743B2 (en) 1987-02-12
SU1398772A3 (ru) 1988-05-23
EP0160865B1 (de) 1988-04-20
PT80386A (de) 1985-06-01
EP0160865A3 (en) 1986-03-12
JPS60239469A (ja) 1985-11-28
DK198785A (da) 1985-11-06
FI851752L (fi) 1985-11-06
DK198785D0 (da) 1985-05-02
KR850008678A (ko) 1985-12-21
EP0160865A2 (de) 1985-11-13
GR851065B (xx) 1985-11-25
DE3562242D1 (en) 1988-05-26
IE57766B1 (en) 1993-03-24
FI851752A0 (fi) 1985-05-03

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