DD217807A5 - Verfahren zur herstellung neuer substituierter tetrapeptide - Google Patents
Verfahren zur herstellung neuer substituierter tetrapeptide Download PDFInfo
- Publication number
- DD217807A5 DD217807A5 DD83257401A DD25740183A DD217807A5 DD 217807 A5 DD217807 A5 DD 217807A5 DD 83257401 A DD83257401 A DD 83257401A DD 25740183 A DD25740183 A DD 25740183A DD 217807 A5 DD217807 A5 DD 217807A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- compound
- salt
- pro
- sta
- phe
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/86—Renin inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH704782 | 1982-12-03 | ||
CH363583 | 1983-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
DD217807A5 true DD217807A5 (de) | 1985-01-23 |
Family
ID=25693492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD83257401A DD217807A5 (de) | 1982-12-03 | 1983-12-01 | Verfahren zur herstellung neuer substituierter tetrapeptide |
Country Status (11)
Country | Link |
---|---|
US (1) | US4595677A (fr) |
EP (1) | EP0111266A3 (fr) |
AU (1) | AU2193783A (fr) |
DD (1) | DD217807A5 (fr) |
DK (1) | DK555983A (fr) |
ES (2) | ES8606394A1 (fr) |
FI (1) | FI834345A (fr) |
GR (1) | GR79104B (fr) |
IL (1) | IL70365A0 (fr) |
NO (1) | NO834441L (fr) |
PT (1) | PT77761B (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4751299A (en) * | 1983-11-18 | 1988-06-14 | Takeda Chemical Industries, Ltd. | Optically active β-lactams and method of their production |
DK110285A (da) * | 1984-03-12 | 1985-09-13 | Pfizer | Polypeptider og polypeptidderivater indeholdende statin eller derivater deraf og farmaceutiske praeparater |
US4636491A (en) * | 1984-03-27 | 1987-01-13 | Merck & Co., Inc. | Renin inhibitory peptides having improved solubility |
EP0163237A3 (fr) * | 1984-05-29 | 1988-04-27 | Merck & Co. Inc. | Inhibiteurs di- et tri-peptidiques de la rénine |
US4880781A (en) * | 1984-08-06 | 1989-11-14 | The Upjohn Company | Renin inhibitory peptides containing an N-alkyl-histidine moiety |
EP0181110A3 (fr) * | 1984-10-22 | 1988-05-11 | Kissei Pharmaceutical Co. Ltd. | Dérivés d'histidine comme inhibiteurs de la rénine |
US4727060A (en) * | 1984-11-13 | 1988-02-23 | Ciba-Geigy Corporation | Novel 5-amino-4-hydroxyvaleryl derivatives |
EP0184855A3 (fr) * | 1984-12-14 | 1989-05-03 | Abbott Laboratories | Composés inhibiteurs de rénine |
PT82077B (fr) * | 1985-02-26 | 1987-09-25 | Sanofi Sa | Procede pour l'obtention des derives aminoalcools peptidiques inhibiteurs de la renine et des proteases acides |
FR2585708B1 (fr) * | 1985-07-31 | 1989-07-07 | Sanofi Sa | Derives aminoalcools peptidiques inhibiteurs de la resine et des proteases acides, leur procede de preparation et leur application en therapeutique |
DE3512128A1 (de) * | 1985-04-03 | 1986-10-09 | Merck Patent Gmbh, 6100 Darmstadt | Peptide |
WO1986006379A1 (fr) | 1985-04-19 | 1986-11-06 | The Upjohn Company | Inhibiteurs de renine a substitution dihalo-statine |
US4882420A (en) * | 1985-04-19 | 1989-11-21 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
DE3514695C2 (de) * | 1985-04-24 | 1994-05-11 | Merck Patent Gmbh | Mittel und Verfahren zur Bestimmung von Calcium |
EP0206807A3 (fr) * | 1985-06-28 | 1988-01-20 | Kissei Pharmaceutical Co. Ltd. | Dérivés d'amino-acides |
CA1290097C (fr) * | 1985-07-24 | 1991-10-01 | Merck & Co., Inc. | Inhibiteurs d'enzymes de type peptide |
US4853463A (en) * | 1985-09-04 | 1989-08-01 | Kissei Pharmaceutical Co., Ltd. | Amino acid derivatives |
JPS6256458A (ja) * | 1985-09-04 | 1987-03-12 | Kissei Pharmaceut Co Ltd | 新規なアミノ酸誘導体 |
DE3538749A1 (de) * | 1985-10-31 | 1987-05-07 | Merck Patent Gmbh | Peptide |
US4894437A (en) * | 1985-11-15 | 1990-01-16 | The Upjohn Company | Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties |
US4705846A (en) * | 1986-03-27 | 1987-11-10 | The Upjohn Company | Novel renin inhibiting peptides having a gamma lactam pseudo dipeptide insert |
JPS6322081A (ja) * | 1986-07-11 | 1988-01-29 | Kissei Pharmaceut Co Ltd | 新規なアミノ酸誘導体 |
EP0321497A1 (fr) * | 1986-09-30 | 1989-06-28 | The Upjohn Company | Peptides inhibiteurs de la rennine presentant des parties nouvelles a terminaison en c |
US4743585A (en) * | 1986-11-21 | 1988-05-10 | Warner-Lambert Company | Renin inhibitors |
US4804743A (en) * | 1987-01-29 | 1989-02-14 | Warner-Lambert Copmany | Proline-containing renin inhibitors |
ATE131066T1 (de) * | 1989-02-10 | 1995-12-15 | Wolfgang Schramm | Mittel zur hemmung von hiv-proteasen. |
CA2359030A1 (fr) * | 1999-01-28 | 2000-08-03 | Chugai Seiyaku Kabushiki Kaisha | Derives phenethylamine substitues |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH14681A (en) * | 1977-11-30 | 1981-11-10 | Pfizer | Phenylglycinamides useful in the treatment of ischaemic heart disease |
NO812612L (no) * | 1980-08-06 | 1982-02-08 | Ferring Pharma Ltd | Enzym-inhibitorer. |
US4478826A (en) * | 1981-10-08 | 1984-10-23 | Merck & Co., Inc. | Renin inhibitory peptides |
US4384994A (en) * | 1981-10-08 | 1983-05-24 | Merck & Co., Inc. | Renin inhibitory peptides |
CA1258748A (fr) * | 1981-10-08 | 1989-08-22 | Daniel F. Veber | Peptides inhibiteurs de la renine |
US4470971A (en) * | 1981-10-19 | 1984-09-11 | Merck & Co., Inc. | Renin inhibitory peptides having His13 |
US4479941A (en) * | 1981-12-10 | 1984-10-30 | Merck & Co., Inc. | Renin inhibitory peptides having PHE13 delection |
CA1245217A (fr) * | 1981-12-10 | 1988-11-22 | Joshua S. Boger | Peptides inhibiteurs de la renine |
FR2531951A1 (fr) * | 1982-08-17 | 1984-02-24 | Sanofi Sa | Derives peptidiques inhibiteurs de proteases acides, procede pour leur preparation et medicaments qui en contiennent |
EP0104041B1 (fr) * | 1982-09-15 | 1988-07-27 | Aktiebolaget Hässle | Inhibiteurs d'enzyme |
US4485099A (en) * | 1983-06-15 | 1984-11-27 | Merck & Co., Inc. | Renin inhibitors containing a C-terminal amide cycle |
-
1983
- 1983-11-23 US US06/554,735 patent/US4595677A/en not_active Expired - Fee Related
- 1983-11-28 FI FI834345A patent/FI834345A/fi not_active Application Discontinuation
- 1983-11-30 PT PT77761A patent/PT77761B/pt unknown
- 1983-12-01 DD DD83257401A patent/DD217807A5/de unknown
- 1983-12-01 ES ES527714A patent/ES8606394A1/es not_active Expired
- 1983-12-01 EP EP83112100A patent/EP0111266A3/fr not_active Withdrawn
- 1983-12-01 GR GR73130A patent/GR79104B/el unknown
- 1983-12-02 DK DK555983A patent/DK555983A/da not_active Application Discontinuation
- 1983-12-02 NO NO834441A patent/NO834441L/no unknown
- 1983-12-02 AU AU21937/83A patent/AU2193783A/en not_active Abandoned
- 1983-12-02 IL IL70365A patent/IL70365A0/xx unknown
-
1985
- 1985-05-24 ES ES543488A patent/ES8702437A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DK555983A (da) | 1984-06-04 |
ES527714A0 (es) | 1986-04-01 |
IL70365A0 (en) | 1984-03-30 |
FI834345A (fi) | 1984-06-04 |
PT77761B (en) | 1986-05-30 |
GR79104B (fr) | 1984-10-02 |
EP0111266A2 (fr) | 1984-06-20 |
EP0111266A3 (fr) | 1987-05-27 |
ES543488A0 (es) | 1987-01-01 |
DK555983D0 (da) | 1983-12-02 |
US4595677A (en) | 1986-06-17 |
ES8606394A1 (es) | 1986-04-01 |
FI834345A0 (fi) | 1983-11-28 |
ES8702437A1 (es) | 1987-01-01 |
NO834441L (no) | 1984-06-04 |
AU2193783A (en) | 1984-06-07 |
PT77761A (en) | 1983-12-01 |
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