DD210280A5 - Verfahren zur herstellung von cephalosporinverbindungen - Google Patents

Verfahren zur herstellung von cephalosporinverbindungen Download PDF

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Publication number
DD210280A5
DD210280A5 DD83248457A DD24845783A DD210280A5 DD 210280 A5 DD210280 A5 DD 210280A5 DD 83248457 A DD83248457 A DD 83248457A DD 24845783 A DD24845783 A DD 24845783A DD 210280 A5 DD210280 A5 DD 210280A5
Authority
DD
German Democratic Republic
Prior art keywords
methyl
carboxylate
group
compound
cephem
Prior art date
Application number
DD83248457A
Other languages
German (de)
English (en)
Inventor
Shimpei Aburaki
Hajime Kamachi
Yukio Narita
Jun Okumura
Takayuki Naito
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/354,851 external-priority patent/US4406899A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DD210280A5 publication Critical patent/DD210280A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DD83248457A 1982-03-04 1983-03-03 Verfahren zur herstellung von cephalosporinverbindungen DD210280A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/354,851 US4406899A (en) 1982-03-04 1982-03-04 Cephalosporins
US35753482A 1982-03-12 1982-03-12

Publications (1)

Publication Number Publication Date
DD210280A5 true DD210280A5 (de) 1984-06-06

Family

ID=26998584

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83248457A DD210280A5 (de) 1982-03-04 1983-03-03 Verfahren zur herstellung von cephalosporinverbindungen

Country Status (29)

Country Link
KR (1) KR870001986B1 (el)
AT (2) AT382155B (el)
AU (1) AU562776B2 (el)
BE (1) BE896086A (el)
CA (1) CA1213882A (el)
CH (1) CH654313A5 (el)
CS (1) CS249512B2 (el)
DD (1) DD210280A5 (el)
DE (1) DE3307550A1 (el)
DK (1) DK156900C (el)
EG (1) EG15934A (el)
ES (2) ES520224A0 (el)
FI (1) FI74973C (el)
FR (1) FR2522659B1 (el)
GB (1) GB2116180B (el)
GR (1) GR77916B (el)
HU (1) HU193158B (el)
IE (1) IE56647B1 (el)
IL (1) IL68011A0 (el)
IT (1) IT1170307B (el)
LU (1) LU84674A1 (el)
MY (1) MY8700943A (el)
NL (2) NL193284C (el)
NZ (1) NZ203312A (el)
PH (1) PH18002A (el)
PT (1) PT76330B (el)
SE (1) SE453091B (el)
SU (1) SU1250173A3 (el)
YU (2) YU43822B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3404906A1 (de) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung
DE3419013A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
DE3789466T2 (de) * 1986-03-17 1994-07-28 Fujisawa Pharmaceutical Co 3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung.
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
ATE201025T1 (de) 1991-03-08 2001-05-15 Biochemie Gmbh Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren
MY108872A (en) * 1991-09-10 1996-11-30 Bristol Myers Squibb Co Preparation of a cephalosporin antibiotic using the syn-isomer of a thiazolyl intermediate.
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
EP1699804B1 (en) * 2003-12-23 2008-02-06 Sandoz Gmbh Process for production of intermediates for use in cefalosporin synthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
IE49099B1 (en) * 1978-10-27 1985-07-24 Glaxo Group Ltd Cephalosporin compounds
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
IT8347826A0 (it) 1983-03-01
PT76330A (en) 1983-04-01
GR77916B (el) 1984-09-25
PT76330B (en) 1986-02-04
FI830689A0 (fi) 1983-03-01
AU1130483A (en) 1983-09-08
SE8301178D0 (sv) 1983-03-03
ES526397A0 (es) 1985-09-16
ES8507557A1 (es) 1985-09-16
ES8403919A1 (es) 1984-04-01
BE896086A (fr) 1983-09-05
NL193284C (nl) 1999-05-06
AT384612B (de) 1987-12-10
AU562776B2 (en) 1987-06-18
GB2116180A (en) 1983-09-21
SU1250173A3 (ru) 1986-08-07
DK86283A (da) 1983-09-05
DK86283D0 (da) 1983-02-24
IL68011A0 (en) 1983-06-15
NL8300755A (nl) 1983-10-03
ATA228285A (de) 1987-05-15
FI74973B (fi) 1987-12-31
KR840004118A (ko) 1984-10-06
NL990039I2 (nl) 2000-04-03
FI74973C (fi) 1988-04-11
DK156900B (da) 1989-10-16
AT382155B (de) 1987-01-26
DE3307550A1 (de) 1983-09-15
NL193284B (nl) 1999-01-04
SE8301178L (sv) 1983-09-05
NL990039I1 (nl) 2000-01-03
YU52383A (en) 1986-02-28
EG15934A (en) 1987-10-30
NZ203312A (en) 1985-12-13
IE56647B1 (en) 1991-10-23
ATA76183A (de) 1986-06-15
YU44777B (en) 1991-02-28
CA1213882A (en) 1986-11-12
FR2522659A1 (fr) 1983-09-09
YU43822B (en) 1989-12-31
DE3307550C2 (el) 1988-11-24
KR870001986B1 (ko) 1987-10-24
IE830455L (en) 1983-09-04
GB2116180B (en) 1985-09-18
GB8305940D0 (en) 1983-04-07
FR2522659B1 (fr) 1986-10-24
LU84674A1 (fr) 1983-11-17
YU149685A (en) 1986-02-28
ES520224A0 (es) 1984-04-01
FI830689L (fi) 1983-09-05
HU193158B (en) 1987-08-28
CS249512B2 (en) 1987-03-12
DK156900C (da) 1990-03-12
MY8700943A (en) 1987-12-31
PH18002A (en) 1985-02-28
SE453091B (sv) 1988-01-11
CH654313A5 (de) 1986-02-14
IT1170307B (it) 1987-06-03

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