FR2522659B1 - Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant - Google Patents

Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant

Info

Publication number
FR2522659B1
FR2522659B1 FR8303334A FR8303334A FR2522659B1 FR 2522659 B1 FR2522659 B1 FR 2522659B1 FR 8303334 A FR8303334 A FR 8303334A FR 8303334 A FR8303334 A FR 8303334A FR 2522659 B1 FR2522659 B1 FR 2522659B1
Authority
FR
France
Prior art keywords
preparation
composition containing
bacterial composition
cephalosporin derivatives
novel cephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8303334A
Other languages
English (en)
Other versions
FR2522659A1 (fr
Inventor
Shimpei Aburaki
Hajime Kamachi
Yukio Narita
Jun Okumura
Takayuki Naito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/354,851 external-priority patent/US4406899A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2522659A1 publication Critical patent/FR2522659A1/fr
Application granted granted Critical
Publication of FR2522659B1 publication Critical patent/FR2522659B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8303334A 1982-03-04 1983-03-01 Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant Expired FR2522659B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/354,851 US4406899A (en) 1982-03-04 1982-03-04 Cephalosporins
US35753482A 1982-03-12 1982-03-12

Publications (2)

Publication Number Publication Date
FR2522659A1 FR2522659A1 (fr) 1983-09-09
FR2522659B1 true FR2522659B1 (fr) 1986-10-24

Family

ID=26998584

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8303334A Expired FR2522659B1 (fr) 1982-03-04 1983-03-01 Nouveaux derives de cephalosporine, leur procede de preparation et composition anti-bacterienne les contenant

Country Status (29)

Country Link
KR (1) KR870001986B1 (fr)
AT (2) AT382155B (fr)
AU (1) AU562776B2 (fr)
BE (1) BE896086A (fr)
CA (1) CA1213882A (fr)
CH (1) CH654313A5 (fr)
CS (1) CS249512B2 (fr)
DD (1) DD210280A5 (fr)
DE (1) DE3307550A1 (fr)
DK (1) DK156900C (fr)
EG (1) EG15934A (fr)
ES (2) ES520224A0 (fr)
FI (1) FI74973C (fr)
FR (1) FR2522659B1 (fr)
GB (1) GB2116180B (fr)
GR (1) GR77916B (fr)
HU (1) HU193158B (fr)
IE (1) IE56647B1 (fr)
IL (1) IL68011A0 (fr)
IT (1) IT1170307B (fr)
LU (1) LU84674A1 (fr)
MY (1) MY8700943A (fr)
NL (2) NL193284C (fr)
NZ (1) NZ203312A (fr)
PH (1) PH18002A (fr)
PT (1) PT76330B (fr)
SE (1) SE453091B (fr)
SU (1) SU1250173A3 (fr)
YU (2) YU43822B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3404906A1 (de) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung
DE3419013A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
CA1284994C (fr) * 1985-08-05 1991-06-18 Murray Arthur Kaplan Sels de cephalosporine, et compositions injectables
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
DE3789466T2 (de) * 1986-03-17 1994-07-28 Fujisawa Pharmaceutical Co 3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung.
CA2011116C (fr) * 1989-03-06 1999-11-16 Murray A. Kaplan Dihydrochlorure de bmy-28142 lyophilise pour usage parenteral
DE69231815T2 (de) 1991-03-08 2001-09-27 Biochemie Ges.M.B.H., Kundl Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
MY108872A (en) * 1991-09-10 1996-11-30 Bristol Myers Squibb Co Preparation of a cephalosporin antibiotic using the syn-isomer of a thiazolyl intermediate.
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
JP4616844B2 (ja) * 2003-12-23 2011-01-19 サンド・ゲーエムベーハー セファロスポリン合成に使用するための中間体の生成プロセス

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2760484C2 (fr) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
CA1131618A (fr) * 1978-10-27 1982-09-14 Cynthia H. O'callaghan Composes de cephalosporine
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
ATA76183A (de) 1986-06-15
GB8305940D0 (en) 1983-04-07
AT384612B (de) 1987-12-10
MY8700943A (en) 1987-12-31
KR840004118A (ko) 1984-10-06
PT76330B (en) 1986-02-04
HU193158B (en) 1987-08-28
DK156900C (da) 1990-03-12
CS249512B2 (en) 1987-03-12
YU43822B (en) 1989-12-31
KR870001986B1 (ko) 1987-10-24
FR2522659A1 (fr) 1983-09-09
IE56647B1 (en) 1991-10-23
NL8300755A (nl) 1983-10-03
SE8301178D0 (sv) 1983-03-03
AU562776B2 (en) 1987-06-18
FI74973B (fi) 1987-12-31
YU52383A (en) 1986-02-28
BE896086A (fr) 1983-09-05
EG15934A (en) 1987-10-30
DK86283A (da) 1983-09-05
GB2116180B (en) 1985-09-18
SU1250173A3 (ru) 1986-08-07
DK156900B (da) 1989-10-16
CH654313A5 (de) 1986-02-14
CA1213882A (fr) 1986-11-12
ATA228285A (de) 1987-05-15
AT382155B (de) 1987-01-26
IE830455L (en) 1983-09-04
IT1170307B (it) 1987-06-03
SE8301178L (sv) 1983-09-05
DK86283D0 (da) 1983-02-24
YU149685A (en) 1986-02-28
ES526397A0 (es) 1985-09-16
ES8507557A1 (es) 1985-09-16
LU84674A1 (fr) 1983-11-17
YU44777B (en) 1991-02-28
ES8403919A1 (es) 1984-04-01
NL193284B (nl) 1999-01-04
GB2116180A (en) 1983-09-21
NL990039I1 (nl) 2000-01-03
FI830689L (fi) 1983-09-05
IT8347826A0 (it) 1983-03-01
PH18002A (en) 1985-02-28
DE3307550C2 (fr) 1988-11-24
AU1130483A (en) 1983-09-08
SE453091B (sv) 1988-01-11
DD210280A5 (de) 1984-06-06
FI74973C (fi) 1988-04-11
NL193284C (nl) 1999-05-06
NL990039I2 (nl) 2000-04-03
ES520224A0 (es) 1984-04-01
FI830689A0 (fi) 1983-03-01
PT76330A (en) 1983-04-01
GR77916B (fr) 1984-09-25
IL68011A0 (en) 1983-06-15
NZ203312A (en) 1985-12-13
DE3307550A1 (de) 1983-09-15

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