DD209455A5 - Verfahren zur herstellung von ascorbinsaeureethern - Google Patents
Verfahren zur herstellung von ascorbinsaeureethern Download PDFInfo
- Publication number
- DD209455A5 DD209455A5 DD83247195A DD24719583A DD209455A5 DD 209455 A5 DD209455 A5 DD 209455A5 DD 83247195 A DD83247195 A DD 83247195A DD 24719583 A DD24719583 A DD 24719583A DD 209455 A5 DD209455 A5 DD 209455A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- ascorbic acid
- alkyl
- compound
- formula
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33934482A | 1982-01-15 | 1982-01-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD209455A5 true DD209455A5 (de) | 1984-05-09 |
Family
ID=23328588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD83247195A DD209455A5 (de) | 1982-01-15 | 1983-01-12 | Verfahren zur herstellung von ascorbinsaeureethern |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0086554A1 (el) |
| JP (1) | JPS58131978A (el) |
| KR (1) | KR840003247A (el) |
| AU (1) | AU1035183A (el) |
| CA (1) | CA1181078A (el) |
| DD (1) | DD209455A5 (el) |
| DK (1) | DK14283A (el) |
| ES (2) | ES8403118A1 (el) |
| FI (1) | FI830078L (el) |
| GB (1) | GB2114571A (el) |
| GR (1) | GR77897B (el) |
| IL (1) | IL67646A0 (el) |
| PL (1) | PL240125A1 (el) |
| PT (1) | PT76083B (el) |
| RO (1) | RO86439B (el) |
| ZA (1) | ZA83173B (el) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552895A (en) * | 1983-03-14 | 1985-11-12 | Eli Lilly And Company | Furo[3,2-b]furan-2-(3H)-ones |
| JPS6058973A (ja) * | 1983-09-13 | 1985-04-05 | Mitsubishi Yuka Yakuhin Kk | γ−プチロラクトン誘導体及びそれを有効成分とする免疫調節剤 |
| JPS60130582A (ja) * | 1983-12-19 | 1985-07-12 | Takeda Chem Ind Ltd | 食品用酸化防止剤，アスコルビン酸誘導体およびその製造法 |
| WO1986006720A1 (en) * | 1985-05-17 | 1986-11-20 | Takeda Chemical Industries, Ltd. | Ascorbic acid derivatives, production thereof, and pharmaceutical preparation therefrom |
| WO1986007592A1 (en) * | 1985-06-18 | 1986-12-31 | Takeda Chemical Industries, Ltd. | Ascorbic acid derivatives, process for their preparation, and preparations containing same |
| JPS60139619A (ja) * | 1983-12-27 | 1985-07-24 | Mutsuyuki Kochi | Ｏ−ベンジリデン−アスコルビン酸又はその塩よりなる抗腫瘍剤 |
| JP2515556B2 (ja) * | 1986-08-29 | 1996-07-10 | 武田薬品工業株式会社 | ヒドロキシブテノライド誘導体およびその製造法 |
| JPH0730066B2 (ja) * | 1988-03-09 | 1995-04-05 | 株式会社日本ハイポックス | アスコルビン酸誘導体及びアスコルビン酸誘導体からなる抗酸化剤 |
| JP2752080B2 (ja) * | 1988-03-09 | 1998-05-18 | 株式会社日本ハイポックス | アスコルビン酸誘導体及びその製造方法並びにアスコルビン酸誘導体からなる抗酸化剤 |
| ATE150750T1 (de) | 1988-09-01 | 1997-04-15 | Takeda Chemical Industries Ltd | Fumagillol-derivate |
| KR970002470B1 (ko) * | 1989-09-11 | 1997-03-05 | 가부시끼가이샤 닛뽕하이폭스 | 아스코르빈산 유도체 |
| US5095126A (en) * | 1990-01-12 | 1992-03-10 | Ohio State University Research Foundation | Efficient synthesis for optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids |
| US5210220A (en) * | 1990-03-07 | 1993-05-11 | Hoffmann-La Roche Inc. | Method for preparing derivatives of ascorbic acid |
| EP0446539A1 (en) * | 1990-03-16 | 1991-09-18 | Merrell Dow Pharmaceuticals Inc. | Novel ascorbic acid derivatives |
| US5270336A (en) * | 1990-03-16 | 1993-12-14 | Merrell Dow Pharmaceuticals Inc. | Ascorbic acid derivatives |
| JPH0429989A (ja) * | 1990-05-24 | 1992-01-31 | Nisshin Flour Milling Co Ltd | Ｌ―アスコルビン酸誘導体の製造法 |
| GB9026114D0 (en) * | 1990-11-30 | 1991-01-16 | Norsk Hydro As | New compounds |
| GB9201274D0 (en) * | 1992-01-21 | 1992-03-11 | Norsk Hydro As | New compounds |
| GB9201275D0 (en) * | 1992-01-21 | 1992-03-11 | Norsk Hydro As | New compounds |
| TW325997B (en) * | 1993-02-02 | 1998-02-01 | Senju Pharma Co | Pharmaceutical composition for preventing and treating retinal diseases |
| US6114355A (en) * | 1993-03-01 | 2000-09-05 | D'amato; Robert | Methods and compositions for inhibition of angiogenesis |
| US6228879B1 (en) | 1997-10-16 | 2001-05-08 | The Children's Medical Center | Methods and compositions for inhibition of angiogenesis |
| US5629327A (en) * | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
| US6908910B2 (en) | 1993-08-06 | 2005-06-21 | The Children's Medical Center Corporation | Estrogenic compounds as anti-mitotic agents |
| US5504074A (en) | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
| DK1586322T3 (da) | 1996-11-05 | 2008-12-01 | Childrens Medical Center | Sammensætninger indeholdende thalidomid og dextamethason til behandling af cancer |
| EP0875246A1 (en) * | 1997-04-04 | 1998-11-04 | Showa Denko Kabushiki Kaisha | Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer |
| AU741933B2 (en) * | 1998-03-27 | 2001-12-13 | Lg Chemical Ltd. | Polyethoxylated ascorbic acid derivatives as a novel antioxidant and process for preparing thereof |
| US6673828B1 (en) | 1998-05-11 | 2004-01-06 | Children's Medical Center Corporation | Analogs of 2-Phthalimidinoglutaric acid |
| US7087592B1 (en) | 1999-08-23 | 2006-08-08 | Entre Med, Inc. | Compositions comprising purified 2-methoxyestradiol and methods of producing same |
| WO2001056566A1 (fr) * | 2000-02-01 | 2001-08-09 | Mutsuyuki Kochi | Compositions inhibitrices de neovascularisation et procede correspondant |
| CN1422157A (zh) * | 2000-03-31 | 2003-06-04 | 安吉奥金尼药品有限公司 | 利用血管破坏活性的分割剂量疗法 |
| DE60118625T2 (de) * | 2001-07-26 | 2007-02-22 | Tagra Biotechnologies Ltd. | Stabilisierte ascorbinsäure -3- phosphat- derivate |
| TWI330533B (en) | 2002-05-15 | 2010-09-21 | Bhn Co Ltd | Composition for angiogenesis inhibition, neoplasm inhibition,or immunostimulation |
| EP1939192A1 (en) * | 2006-12-28 | 2008-07-02 | Neuropharma S.A. | Cyclopentanone derivatives, method of synthesis and uses thereof |
| FR2955493B1 (fr) * | 2010-01-28 | 2012-02-24 | Oreal | Utilisation de derives d'acide ascorbique en coloration des fibres keratiniques humaines, composition les comprenant, procede de coloration et dispositif |
| JP5602456B2 (ja) * | 2010-02-24 | 2014-10-08 | 日本精化株式会社 | アスコルビン酸誘導体 |
| US9550744B2 (en) * | 2013-09-25 | 2017-01-24 | University Of Florida Research Foundation, Inc. | Vitamin C prodrugs and uses thereof |
| US10105407B2 (en) * | 2015-06-09 | 2018-10-23 | John P. Crow, JR. | Methods of extraction of nitrosylated or nitrated derivatives of ascorbic acid from myriciaria dubia and methods of synthesis thereof |
| WO2017093354A1 (en) | 2015-11-30 | 2017-06-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Nmdar antagonists for the treatment of diseases associated with angiogenesis |
-
1983
- 1983-01-10 RO RO109663A patent/RO86439B/ro unknown
- 1983-01-10 IL IL67646A patent/IL67646A0/xx unknown
- 1983-01-10 FI FI830078A patent/FI830078L/fi not_active Application Discontinuation
- 1983-01-11 CA CA000419220A patent/CA1181078A/en not_active Expired
- 1983-01-11 PT PT76083A patent/PT76083B/pt unknown
- 1983-01-11 ZA ZA83173A patent/ZA83173B/xx unknown
- 1983-01-12 DD DD83247195A patent/DD209455A5/de unknown
- 1983-01-12 PL PL24012583A patent/PL240125A1/xx unknown
- 1983-01-13 GB GB08300907A patent/GB2114571A/en not_active Withdrawn
- 1983-01-13 ES ES518968A patent/ES8403118A1/es not_active Expired
- 1983-01-13 AU AU10351/83A patent/AU1035183A/en not_active Abandoned
- 1983-01-13 JP JP58005144A patent/JPS58131978A/ja active Pending
- 1983-01-13 GR GR70253A patent/GR77897B/el unknown
- 1983-01-13 EP EP83300174A patent/EP0086554A1/en not_active Ceased
- 1983-01-14 DK DK14283A patent/DK14283A/da not_active Application Discontinuation
- 1983-01-14 KR KR1019830000115A patent/KR840003247A/ko not_active Application Discontinuation
- 1983-08-30 ES ES525239A patent/ES8502698A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK14283A (da) | 1983-07-16 |
| RO86439A (ro) | 1985-03-15 |
| GB8300907D0 (en) | 1983-02-16 |
| ZA83173B (en) | 1984-08-29 |
| FI830078A0 (fi) | 1983-01-10 |
| GR77897B (el) | 1984-09-25 |
| FI830078L (fi) | 1983-07-16 |
| ES518968A0 (es) | 1984-03-01 |
| JPS58131978A (ja) | 1983-08-06 |
| IL67646A0 (en) | 1983-05-15 |
| PT76083A (en) | 1983-02-01 |
| KR840003247A (ko) | 1984-08-20 |
| PL240125A1 (en) | 1984-04-24 |
| CA1181078A (en) | 1985-01-15 |
| AU1035183A (en) | 1983-07-21 |
| RO86439B (ro) | 1985-03-31 |
| ES8403118A1 (es) | 1984-03-01 |
| ES525239A0 (es) | 1985-01-16 |
| ES8502698A1 (es) | 1985-01-16 |
| EP0086554A1 (en) | 1983-08-24 |
| DK14283D0 (da) | 1983-01-14 |
| PT76083B (en) | 1986-01-09 |
| GB2114571A (en) | 1983-08-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD209455A5 (de) | Verfahren zur herstellung von ascorbinsaeureethern | |
| DE2915037C3 (de) | Neue N-substituierte Moranolinderivate | |
| DE69627042T2 (de) | Isocumarinderivate und deren verwendung in medikamenten | |
| US4552888A (en) | Ascorbic acid ethers in angiogene | |
| EP0247320A2 (de) | 5-Arylalkyl-4-alkoxy-2(5H)-furanone, Zwischenprodukte und Verfahren zu ihrer Herstellung sowie ihre Anwendung als therapeutische Wirkstoffe | |
| DE3788982T2 (de) | Trans-6-[2-(N-heteroaryl)-3,5-disubstituiertes)pyrazol-4-yl)-ethyl] oder -ethenyl]tetrahydro-4-hydroxypyran-2-on-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung. | |
| DE2923368A1 (de) | Neue 5-fluor-( beta -uridin oder 2'-desoxy- beta -uridin)-derivate, verfahren zur herstellung derselben und carcinostatische mittel mit einem gehalt derselben | |
| DE69811500T2 (de) | Kristallmodifikation von 1-(2,6-difluorbenzyl)-1h-1,2,3-triazol-4-carbonsäureamid und seine verwendung als antiepileptikum | |
| DE2839388A1 (de) | Imidazolylvinylaether und deren verwendung | |
| DE60131416T2 (de) | Chirale fluochinolon-argininsalzformen | |
| DE69623760T2 (de) | Kaliumionen-kanal-blocker | |
| DE69102477T2 (de) | 3-Aminochroman-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen. | |
| DE3438244C2 (el) | ||
| CH643830A5 (de) | Bis-moranolin-derivate. | |
| DE68905361T2 (de) | Trienische Derivate mit chromenischer Struktur, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen. | |
| DE3121175A1 (de) | Erythro-1,2,3-triphenyl-1-pentanon-derivate sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
| DE3709699C2 (de) | 5-Fluoruracil-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung | |
| DE2723450A1 (de) | Uracilderivate und verfahren zu ihrer herstellung | |
| DE2909646B1 (de) | N-Alkenylmoranolinderivate | |
| DE2650231A1 (de) | Neue imidazolverbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel | |
| DE69809564T2 (de) | 2- 4-[4-(4,5-dichlor-2-methylimidazol-1-yl)butyl]piperazin-1-yl -5-fluorpyrimidin, seine herstellung und therapeutische verwendung | |
| DE2932357A1 (de) | Crotonamidderivate und sie enthaltende carcinostatische arzneimittel | |
| DE1545581A1 (de) | Neue Penicillinaldehyde und Verfahren zu deren Herstellung | |
| CH687001A5 (de) | Pharmazeutisches Praeparat zur Modulierung der Immunreaktion. | |
| DE1795125C (de) | Chinolinderivate, ein Verfahren zu ihrer Herstellung und Arzneimittel |