DD207732A5 - Verfahren zur herstellung eines polypeptids, das im wesentlichen aus der aminosaeuresequenz eines tierischen interferonsbesteht - Google Patents

Verfahren zur herstellung eines polypeptids, das im wesentlichen aus der aminosaeuresequenz eines tierischen interferonsbesteht Download PDF

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Publication number
DD207732A5
DD207732A5 DD83248612A DD24861283A DD207732A5 DD 207732 A5 DD207732 A5 DD 207732A5 DD 83248612 A DD83248612 A DD 83248612A DD 24861283 A DD24861283 A DD 24861283A DD 207732 A5 DD207732 A5 DD 207732A5
Authority
DD
German Democratic Republic
Prior art keywords
interferon
dna
bovine
gene
polypeptide
Prior art date
Application number
DD83248612A
Other languages
German (de)
English (en)
Inventor
Daniel J Capon
Goeddel David Van Norman
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DD207732A5 publication Critical patent/DD207732A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/71Expression systems using regulatory sequences derived from the trp-operon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DD83248612A 1982-03-08 1983-03-08 Verfahren zur herstellung eines polypeptids, das im wesentlichen aus der aminosaeuresequenz eines tierischen interferonsbesteht DD207732A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35529882A 1982-03-08 1982-03-08
US43812882A 1982-11-01 1982-11-01

Publications (1)

Publication Number Publication Date
DD207732A5 true DD207732A5 (de) 1984-03-14

Family

ID=26998783

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83248612A DD207732A5 (de) 1982-03-08 1983-03-08 Verfahren zur herstellung eines polypeptids, das im wesentlichen aus der aminosaeuresequenz eines tierischen interferonsbesteht

Country Status (17)

Country Link
EP (1) EP0088622B1 (es)
JP (4) JP2633227B2 (es)
AT (1) ATE123813T1 (es)
AU (1) AU572447B2 (es)
CA (1) CA1339936C (es)
DD (1) DD207732A5 (es)
DE (2) DE3382789T2 (es)
DK (1) DK171790B1 (es)
ES (2) ES520358A0 (es)
FR (1) FR2530662B1 (es)
GB (1) GB2116566B (es)
IE (1) IE54592B1 (es)
IL (1) IL68059A (es)
NZ (1) NZ203493A (es)
PL (1) PL153902B1 (es)
PT (1) PT76353B (es)
YU (1) YU46722B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58146281A (ja) * 1981-10-19 1983-08-31 Suntory Ltd 酵母細胞の形質転換法
JPS60500574A (ja) * 1983-02-24 1985-04-25 インステイチユト オルガニチエスコゴ シンテザ アカデミイ ナウク ラトビイスコイ エスエスア−ル ヒト白血球インタ−フェロンn及び細菌細胞におけるその製造方法
ZA843275B (en) * 1983-05-05 1984-12-24 Hoffmann La Roche Novel vectors for interferon expression
WO1985002200A1 (en) * 1983-11-14 1985-05-23 Chiron Corporation Interleukin-2 production using cloned genes for interleukin-2 and yeast alpha-factor
IL71555A (en) * 1984-04-15 1992-06-21 State Of Israel Israel Inst Fo Bovine interferon
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
DE3500961A1 (de) * 1985-01-14 1986-07-17 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Escherichia-coli-staemme, dna-teilsequenzen dieser staemme und herstellungsverfahren
US4882282A (en) * 1985-08-16 1989-11-21 Immunex Corporation DNA sequences encoding bovine interleukin-2
US4709324A (en) * 1985-11-27 1987-11-24 Motorola, Inc. Data processor control unit having an interrupt service using instruction prefetch redirection
ZA877924B (en) * 1985-12-04 1987-08-26 Immunex Corp Cloning,characterization,and expression of bovine gamma interferon
DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
EP0271447B1 (de) * 1986-12-12 1993-03-10 Ciba-Geigy Ag Vorbeugende Massnahmen zur Verhinderung der "Komplexen Respiratorischen Erkrankung bei Rindern" durch Verabreichung von Interferon
ES2071612T3 (es) * 1987-12-29 1995-07-01 Toray Industries Plasmido sintetico, transformante, gen del interferon felino y metodo para producir interferon felino.
WO1989009065A1 (en) * 1988-03-23 1989-10-05 University Of Georgia Research Foundation, Inc. Large-scale production of bovine leukocyte interferon
CA2019803C (en) * 1989-06-29 2000-04-25 Akira Yanai Feline interferon and process for production thereof
US5885567A (en) * 1993-10-22 1999-03-23 University Of Connecticut Treatment of infection in fowl by oral administration of avian interferon proteins
US5641656A (en) * 1993-10-22 1997-06-24 University Of Connecticut Nucleic acids encoding avian interferon (IFN) proteins and recombinant methods using them
FR2825716B1 (fr) 2001-06-11 2004-09-24 Genodyssee Nouveaux polynucleotides et polypeptides de l'ifn alpha 7
RU2335535C2 (ru) * 2002-10-08 2008-10-10 Дау Агросайенсиз Ллс Измененные рекомбинантные клетки (arc), предназначенные для продуцирования и доставки антивирусных агентов, адъювантов и акселераторов вакцин
NZ540043A (en) * 2002-11-18 2007-11-30 Maxygen Inc Isolated or recombinant Interferon-alpha polypeptides and conjugates
CN109206502B (zh) * 2018-09-26 2022-03-04 东北农业大学 一种猫干扰素ω及其制备方法和在抗病毒中的应用
CN112457391B (zh) * 2020-11-02 2022-10-04 天津大学 猪干扰素α、β、λ1在酿酒酵母中共分泌表达的方法及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980002375A1 (en) * 1977-09-23 1980-11-13 Hem Res Inc High purity animal interferons
JPS56131598A (en) * 1980-03-19 1981-10-15 Japan Found Cancer Novel recombinant plasmid having gene of human fibroblastic interferon messenger rna
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
EP0032134B2 (en) * 1980-01-08 1993-10-13 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing human interferon-alpha like polypeptides
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
ATE25985T1 (de) * 1980-06-12 1987-04-15 Japan Found Cancer Plasmid.
CH657141A5 (de) * 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
IT1139487B (it) * 1980-09-25 1986-09-24 Genentech Inc Produzione microbica di interferone di fibroblasti umani
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna

Also Published As

Publication number Publication date
PT76353B (en) 1986-02-27
PL240926A1 (en) 1983-10-24
EP0088622B1 (en) 1995-06-14
FR2530662B1 (fr) 1985-11-15
JP2721139B2 (ja) 1998-03-04
YU55583A (en) 1986-04-30
EP0088622A3 (en) 1984-08-01
AU1212283A (en) 1983-09-15
GB2116566B (en) 1985-11-27
NZ203493A (en) 1987-08-31
GB8306225D0 (en) 1983-04-13
ES8605534A1 (es) 1986-04-01
FR2530662A1 (fr) 1984-01-27
ES8500327A1 (es) 1984-11-01
DE3308030A1 (de) 1983-09-29
EP0088622A2 (en) 1983-09-14
JPS58224690A (ja) 1983-12-27
ES520358A0 (es) 1984-11-01
GB2116566A (en) 1983-09-28
ES533485A0 (es) 1986-04-01
JPH0948799A (ja) 1997-02-18
IE830471L (en) 1983-09-08
DK111183D0 (da) 1983-03-07
DE3308030C2 (de) 1996-03-28
IE54592B1 (en) 1989-12-06
DE3382789T2 (de) 1995-12-14
JPH06315385A (ja) 1994-11-15
ATE123813T1 (de) 1995-06-15
IL68059A (en) 1990-11-05
JP2633227B2 (ja) 1997-07-23
IL68059A0 (en) 1983-06-15
YU46722B (sh) 1994-04-05
DK111183A (da) 1983-09-09
JPH08187088A (ja) 1996-07-23
PL153902B1 (en) 1991-06-28
DK171790B1 (da) 1997-05-26
PT76353A (en) 1983-04-01
CA1339936C (en) 1998-06-30
JP2633510B2 (ja) 1997-07-23
DE3382789D1 (de) 1995-07-20
JP2677759B2 (ja) 1997-11-17
AU572447B2 (en) 1988-05-12

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