DD202452A5 - Verfahren zur herstellung von makroliden - Google Patents

Verfahren zur herstellung von makroliden Download PDF

Info

Publication number
DD202452A5
DD202452A5 DD81231807A DD23180781A DD202452A5 DD 202452 A5 DD202452 A5 DD 202452A5 DD 81231807 A DD81231807 A DD 81231807A DD 23180781 A DD23180781 A DD 23180781A DD 202452 A5 DD202452 A5 DD 202452A5
Authority
DD
German Democratic Republic
Prior art keywords
domm
dihydro
doml
acid
preparation
Prior art date
Application number
DD81231807A
Other languages
German (de)
English (en)
Inventor
Richard H Baltz
Gene M Wild
Eugene T Seno
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD202452A5 publication Critical patent/DD202452A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/08Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/54Streptomyces fradiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DD81231807A 1980-07-24 1981-07-15 Verfahren zur herstellung von makroliden DD202452A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8024211 1980-07-24

Publications (1)

Publication Number Publication Date
DD202452A5 true DD202452A5 (de) 1983-09-14

Family

ID=10514997

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81231807A DD202452A5 (de) 1980-07-24 1981-07-15 Verfahren zur herstellung von makroliden

Country Status (23)

Country Link
EP (1) EP0045157B1 (xx)
JP (1) JPS5750998A (xx)
KR (1) KR840001193B1 (xx)
AR (1) AR227325A1 (xx)
AU (1) AU7286281A (xx)
CA (1) CA1174994A (xx)
CS (1) CS228512B2 (xx)
DD (1) DD202452A5 (xx)
DE (1) DE3163204D1 (xx)
DK (1) DK313081A (xx)
ES (1) ES503957A0 (xx)
FI (1) FI812209L (xx)
GB (1) GB2080798B (xx)
GR (1) GR74509B (xx)
HU (1) HU189519B (xx)
IE (1) IE51619B1 (xx)
IL (1) IL63312A (xx)
PH (1) PH18089A (xx)
PL (1) PL232190A1 (xx)
PT (1) PT73370B (xx)
RO (1) RO81671B (xx)
YU (1) YU173981A (xx)
ZA (1) ZA814789B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411892A (en) * 1982-05-03 1983-10-25 Pfizer Inc. Tylosin macrolide antibiotics from streptomyces
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
US4820694A (en) * 1986-09-29 1989-04-11 Eli Lilly And Company Modifications of 3-O-demethylmycinose in macrocin and lactenocin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201843A (en) * 1975-08-01 1980-05-06 Sanraku Ocean Co., Ltd. Process for manufacturing tylosin derivatives

Also Published As

Publication number Publication date
CA1174994A (en) 1984-09-25
GB2080798B (en) 1984-07-25
EP0045157A1 (en) 1982-02-03
IE811581L (en) 1982-01-24
GR74509B (xx) 1984-06-29
HU189519B (en) 1986-07-28
RO81671B (ro) 1983-04-30
ES8206622A1 (es) 1982-05-16
RO81671A (ro) 1983-04-29
GB2080798A (en) 1982-02-10
AU7286281A (en) 1982-01-28
FI812209L (fi) 1982-01-25
IE51619B1 (en) 1987-01-21
PL232190A1 (xx) 1982-03-29
PT73370A (en) 1981-08-01
JPS5750998A (en) 1982-03-25
ES503957A0 (es) 1982-05-16
CS228512B2 (en) 1984-05-14
ZA814789B (en) 1983-02-23
IL63312A0 (en) 1981-10-30
DE3163204D1 (en) 1984-05-24
DK313081A (da) 1982-01-25
PT73370B (en) 1982-08-09
KR840001193B1 (ko) 1984-08-18
EP0045157B1 (en) 1984-04-18
PH18089A (en) 1985-03-20
IL63312A (en) 1985-04-30
YU173981A (en) 1983-09-30
AR227325A1 (es) 1982-10-15

Similar Documents

Publication Publication Date Title
DD159644A5 (de) Verfahren zur herstellung von makroliden
DE2813021A1 (de) Antibiotikum ka-6606
DD211565A5 (de) Verfahren zur herstellung von 4"-epi-erythromycin a und derivaten hiervon als brauchbare antibakterielle mittel
DD202032A5 (de) Verfahren zur herstellung von makroliden
DE2167325C2 (de) Antibiotikum A-201B und Verfahren zu seiner Herstellung
DE2804517B2 (de) Epimere 4"-substituierte Aminoderivate des Oleandomycins und deren Verwendung bei der Bekämpfung von Bakterien
DE2918711C2 (xx)
DE2336811C2 (de) Antibiotikum A-2315, Verfahren zu seiner Herstellung und seine Verwendung
DD202452A5 (de) Verfahren zur herstellung von makroliden
DD202047A5 (de) Verfahren zur herstellung des makrolids 20-dihydro-20,23-dideoxytylonolid
DE2804507C2 (de) 4"-Desoxy-4"-amino-erythromycin-A und dessen Derivate sowie diese Verbindungen enthaltende antibakterielle Mittel
DD159645A5 (de) Verfahren zur herstellung von makroliden
DE2014277C3 (de) Verfahren zur Herstellung von Acylderivaten des Antibiotikums T-2636 C
EP0236894B1 (de) Efomycin G, seine Herstellung und seine Verwendung als Leistungsförderer bei Tieren
DE2839668A1 (de) Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellung
DE2928373C2 (de) Antibiotika KA-7038I bis KA-7038VII, deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende antibiotische Mittel
DE2209018C2 (de) Glycopeptid-Antibioticum-A-4696-Hydrochlorid und dieses enthaltendes Tierfuttermittel
DE2654266C3 (de) Verfahren zur mikrobiologischen Herstellung von 5,10,11,1 la-Tetrahydro-9,1 ldihydroxy-e-methyl-Soxo-lH-pyrrolo [2,1-c] [1,4] benzodiazepin-2acrylamid
DD140477A5 (de) Verfahren zur herstellung von a-40104-antibiotika und derivaten davon
DD206563A5 (de) Verfahren zur herstellung von makroliden
DE1939045C (de) Verfahren zur Herstellung des Antibiotikums 289-F
DE941013C (de) Verfahren zur Herstellung von Erythromycin B
AT267057B (de) Verfahren zur Herstellung eines neuen Antibiotikums
CH642975A5 (de) 4''-deoxy-4''-glyoxamido- und -carbonylthioformamidoderivate von oleandomycin und dessen estern, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
DE920934C (de) Verfahren zur Erzeugung eines Antibiotikums und dessen Salzen