DD202452A5 - Verfahren zur herstellung von makroliden - Google Patents

Verfahren zur herstellung von makroliden Download PDF

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Publication number
DD202452A5
DD202452A5 DD81231807A DD23180781A DD202452A5 DD 202452 A5 DD202452 A5 DD 202452A5 DD 81231807 A DD81231807 A DD 81231807A DD 23180781 A DD23180781 A DD 23180781A DD 202452 A5 DD202452 A5 DD 202452A5
Authority
DD
German Democratic Republic
Prior art keywords
domm
dihydro
doml
acid
preparation
Prior art date
Application number
DD81231807A
Other languages
German (de)
English (en)
Inventor
Richard H Baltz
Gene M Wild
Eugene T Seno
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD202452A5 publication Critical patent/DD202452A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/08Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/54Streptomyces fradiae

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DD81231807A 1980-07-24 1981-07-15 Verfahren zur herstellung von makroliden DD202452A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8024211 1980-07-24

Publications (1)

Publication Number Publication Date
DD202452A5 true DD202452A5 (de) 1983-09-14

Family

ID=10514997

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81231807A DD202452A5 (de) 1980-07-24 1981-07-15 Verfahren zur herstellung von makroliden

Country Status (23)

Country Link
EP (1) EP0045157B1 (xx)
JP (1) JPS5750998A (xx)
KR (1) KR840001193B1 (xx)
AR (1) AR227325A1 (xx)
AU (1) AU7286281A (xx)
CA (1) CA1174994A (xx)
CS (1) CS228512B2 (xx)
DD (1) DD202452A5 (xx)
DE (1) DE3163204D1 (xx)
DK (1) DK313081A (xx)
ES (1) ES503957A0 (xx)
FI (1) FI812209L (xx)
GB (1) GB2080798B (xx)
GR (1) GR74509B (xx)
HU (1) HU189519B (xx)
IE (1) IE51619B1 (xx)
IL (1) IL63312A (xx)
PH (1) PH18089A (xx)
PL (1) PL232190A1 (xx)
PT (1) PT73370B (xx)
RO (1) RO81671B (xx)
YU (1) YU173981A (xx)
ZA (1) ZA814789B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411892A (en) * 1982-05-03 1983-10-25 Pfizer Inc. Tylosin macrolide antibiotics from streptomyces
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
US4820694A (en) * 1986-09-29 1989-04-11 Eli Lilly And Company Modifications of 3-O-demethylmycinose in macrocin and lactenocin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201843A (en) * 1975-08-01 1980-05-06 Sanraku Ocean Co., Ltd. Process for manufacturing tylosin derivatives

Also Published As

Publication number Publication date
ZA814789B (en) 1983-02-23
PH18089A (en) 1985-03-20
PT73370A (en) 1981-08-01
IE51619B1 (en) 1987-01-21
RO81671A (ro) 1983-04-29
YU173981A (en) 1983-09-30
CS228512B2 (en) 1984-05-14
DE3163204D1 (en) 1984-05-24
ES8206622A1 (es) 1982-05-16
EP0045157A1 (en) 1982-02-03
CA1174994A (en) 1984-09-25
PT73370B (en) 1982-08-09
KR840001193B1 (ko) 1984-08-18
IL63312A (en) 1985-04-30
GB2080798A (en) 1982-02-10
FI812209L (fi) 1982-01-25
AR227325A1 (es) 1982-10-15
DK313081A (da) 1982-01-25
IE811581L (en) 1982-01-24
ES503957A0 (es) 1982-05-16
EP0045157B1 (en) 1984-04-18
AU7286281A (en) 1982-01-28
IL63312A0 (en) 1981-10-30
GB2080798B (en) 1984-07-25
PL232190A1 (xx) 1982-03-29
HU189519B (en) 1986-07-28
GR74509B (xx) 1984-06-29
JPS5750998A (en) 1982-03-25
RO81671B (ro) 1983-04-30

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