DD202085A5 - Verfahren zur herstellung von human-fibroblasten-interferon - Google Patents

Verfahren zur herstellung von human-fibroblasten-interferon Download PDF

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Publication number
DD202085A5
DD202085A5 DD81233598A DD23359881A DD202085A5 DD 202085 A5 DD202085 A5 DD 202085A5 DD 81233598 A DD81233598 A DD 81233598A DD 23359881 A DD23359881 A DD 23359881A DD 202085 A5 DD202085 A5 DD 202085A5
Authority
DD
German Democratic Republic
Prior art keywords
plasmid
dna
interferon
fragment
cdna
Prior art date
Application number
DD81233598A
Other languages
German (de)
English (en)
Inventor
Roberto Crea
David V N Goeddel
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26886463&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD202085(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DD202085A5 publication Critical patent/DD202085A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DD81233598A 1980-09-25 1981-09-25 Verfahren zur herstellung von human-fibroblasten-interferon DD202085A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19079980A 1980-09-25 1980-09-25
US29189281A 1981-08-11 1981-08-11

Publications (1)

Publication Number Publication Date
DD202085A5 true DD202085A5 (de) 1983-08-24

Family

ID=26886463

Family Applications (3)

Application Number Title Priority Date Filing Date
DD81249414A DD209652A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung eines replikablen vektors
DD81233598A DD202085A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung von human-fibroblasten-interferon
DD81249415A DD209477A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung von mikroorganismen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD81249414A DD209652A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung eines replikablen vektors

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD81249415A DD209477A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung von mikroorganismen

Country Status (33)

Country Link
US (1) US5460811A (en:Method)
EP (1) EP0048970A3 (en:Method)
AT (1) AT380694B (en:Method)
AU (1) AU582110B2 (en:Method)
BR (1) BR8106137A (en:Method)
CA (1) CA1341569C (en:Method)
CH (2) CH651309A5 (en:Method)
DD (3) DD209652A5 (en:Method)
DE (1) DE3138096A1 (en:Method)
DK (1) DK423381A (en:Method)
ES (3) ES8307297A1 (en:Method)
FI (1) FI812993L (en:Method)
FR (1) FR2490675B1 (en:Method)
GB (1) GB2098996B (en:Method)
GR (1) GR81946B (en:Method)
HK (1) HK43686A (en:Method)
IE (1) IE51679B1 (en:Method)
IL (1) IL63916A0 (en:Method)
IT (1) IT1139487B (en:Method)
KE (1) KE3630A (en:Method)
LU (1) LU83648A1 (en:Method)
MC (1) MC1423A1 (en:Method)
MT (1) MTP900B (en:Method)
MY (1) MY8600634A (en:Method)
NL (1) NL8104400A (en:Method)
NO (1) NO813248L (en:Method)
NZ (1) NZ198445A (en:Method)
OA (1) OA06908A (en:Method)
PL (1) PL233194A1 (en:Method)
PT (1) PT73728B (en:Method)
SE (1) SE8105657L (en:Method)
YU (1) YU44835B (en:Method)
ZW (1) ZW23981A1 (en:Method)

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DK33181A (da) * 1980-02-06 1981-08-07 Searle & Co Fremgangsmaade til fremstilling af et interferonlignende protein
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
CA1341604C (en) 1980-04-03 2010-05-04 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
ATE25985T1 (de) * 1980-06-12 1987-04-15 Japan Found Cancer Plasmid.
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
JPS58110600A (ja) * 1981-12-25 1983-07-01 Kyowa Hakko Kogyo Co Ltd ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
AU575301B2 (en) * 1982-10-08 1988-07-28 Juridical Foundation, Japanese Foundation For Cancer Research Novel vector
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
US4620948A (en) * 1982-12-22 1986-11-04 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4512922A (en) * 1982-12-22 1985-04-23 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4511502A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
GR79124B (en:Method) * 1982-12-22 1984-10-02 Genentech Inc
US4518526A (en) * 1982-12-22 1985-05-21 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4599197A (en) * 1982-12-22 1986-07-08 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US5683688A (en) * 1984-05-31 1997-11-04 Genentech, Inc. Unglycosylated recombinant human lymphotoxin polypeptides and compositions
GB8414354D0 (en) * 1984-06-05 1984-07-11 Biogen Nv Purifying protein
ATE47864T1 (de) * 1984-08-27 1989-11-15 Genentech Inc Verschiedenartige familie von menschlichen leukozyten-interferonen, zusammensetzungen, die diese enthalten, verfahren zu ihrer herstellung, sowie dna und transfektierte wirte hierfuer.
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
US4680262A (en) * 1984-10-05 1987-07-14 Genentech, Inc. Periplasmic protein recovery
US5618920A (en) 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
EP0237019A3 (en) * 1986-03-14 1988-03-09 Toray Industries, Inc. Interferon conjugate and production thereof using recombinant gene
GB9022543D0 (en) * 1990-10-17 1990-11-28 Wellcome Found Antibody production
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US20050002902A1 (en) * 1995-12-28 2005-01-06 Liming Yu Hybrid with interferon-alpha and an immunoglobulin Fc for treatment of tumors and viral infections
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
US20030026779A1 (en) * 1999-10-15 2003-02-06 Liming Yu Treatment of tumors and viral infections with a hybrid conjugate of interferon and an immunoglobulin Fc
US6713609B1 (en) * 1996-07-16 2004-03-30 Genentech, Inc. Monoclonal antibodies to type I interferon receptor
JP3576819B2 (ja) 1997-07-30 2004-10-13 キヤノン株式会社 情報処理装置及び印刷制御方法並びに記憶媒体
US20030018174A1 (en) * 1997-10-06 2003-01-23 Genentech, Inc. Monoclonal antibodies to IFNAR2
AU780836B2 (en) 1999-03-24 2005-04-21 Serono Genetics Institute S.A. Genomic sequence of the (purH) gene and (purH)-related biallelic markers
DK2236152T3 (da) 2000-04-12 2014-07-07 Novozymes Biopharma Dk As Albuminfusionsproteiner
JP4394350B2 (ja) * 2001-01-09 2010-01-06 ベイラー リサーチ インスティテュート 対象における自己免疫疾患の治療法及びｉｎｖｉｔｒｏ診断アッセイ
KR101271635B1 (ko) * 2001-12-21 2013-06-12 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질
EP1997829A1 (en) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin fusion proteins
MXPA05006945A (es) * 2002-12-26 2005-12-14 Mountain View Pharmaceuticals Conjugados polimericos de citoquinas, quimiocinas, factores de crecimiento, hormonas polipeptidicas y sus antagonistas con actividad conservada de union al receptor.
PT1667708E (pt) 2002-12-26 2012-09-14 Mountain View Pharmaceuticals Conjugados de interferão-beta-1b e polietileno glicol apresentando uma potência biológica in vitro aumentada
CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
US8906676B2 (en) 2004-02-02 2014-12-09 Ambrx, Inc. Modified human four helical bundle polypeptides and their uses
JP2008543335A (ja) * 2005-06-22 2008-12-04 ジェネンテック・インコーポレーテッド Ｉｆｎａｒ２を標的とするための方法と組成物
EP2247743B1 (en) 2008-02-08 2016-04-06 Ambrx, Inc. Modified leptin polypeptides and their uses

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT373279B (de) * 1977-11-08 1984-01-10 Genentech Inc Verfahren zur herstellung eines rekombinationsclonbildungstraegers
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
IN150740B (en:Method) * 1978-11-24 1982-12-04 Hoffmann La Roche
US4332892A (en) * 1979-01-15 1982-06-01 President And Fellows Of Harvard College Protein synthesis
US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4289689A (en) * 1980-03-14 1981-09-15 Hoffmann-La Roche Inc. Preparation of homogeneous human fibroblast interferon
CH648331A5 (de) * 1979-07-31 1985-03-15 Hoffmann La Roche Homogenes fibroblasten-interferon und dessen herstellung.
AU538665B2 (en) * 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
US4418149A (en) * 1980-01-10 1983-11-29 President And Fellows Of Harvard College Fused hybrid gene
GB2068970B (en) * 1980-02-06 1983-06-22 Searle & Co Recombinant dna technique for the preparation of a protein resembling human interferon
DK33181A (da) * 1980-02-06 1981-08-07 Searle & Co Fremgangsmaade til fremstilling af et interferonlignende protein
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
CA1341604C (en) * 1980-04-03 2010-05-04 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
ATE25985T1 (de) * 1980-06-12 1987-04-15 Japan Found Cancer Plasmid.
US4874702A (en) * 1980-09-08 1989-10-17 Biogen, Inc. Vectors and methods for making such vectors and for expressive cloned genes

Also Published As

Publication number Publication date
AU582110B2 (en) 1989-03-16
IE51679B1 (en) 1987-02-04
HK43686A (en) 1986-06-20
ES505742A0 (es) 1983-07-01
FR2490675B1 (fr) 1985-11-15
MY8600634A (en) 1986-12-31
EP0048970A3 (en) 1982-08-18
ES8306325A1 (es) 1983-06-01
PL233194A1 (en) 1983-07-18
ATA410381A (de) 1985-11-15
US5460811A (en) 1995-10-24
EP0048970A2 (en) 1982-04-07
IL63916A0 (en) 1981-12-31
FI812993A7 (fi) 1982-03-26
GR81946B (en:Method) 1984-12-12
GB2098996A (en) 1982-12-01
BR8106137A (pt) 1982-06-15
SE8105657L (sv) 1982-03-26
IT1139487B (it) 1986-09-24
NL8104400A (nl) 1982-04-16
AU7564981A (en) 1982-04-01
ES515032A0 (es) 1983-06-01
OA06908A (fr) 1983-05-31
CA1341569C (en) 2008-03-25
DD209477A5 (de) 1984-05-09
KE3630A (en) 1986-05-16
AT380694B (de) 1986-06-25
CH651309A5 (de) 1985-09-13
YU44835B (en) 1991-04-30
CH656388A5 (de) 1986-06-30
DD209652A5 (de) 1984-05-16
IT8124109A0 (it) 1981-09-23
ES8307297A1 (es) 1983-07-01
ES8306324A1 (es) 1983-06-01
NZ198445A (en) 1984-05-31
YU229781A (en) 1984-02-29
IE812224L (en) 1982-03-25
GB2098996B (en) 1985-02-06
PT73728A (en) 1981-10-01
ZW23981A1 (en) 1982-04-28
DK423381A (da) 1982-03-26
FI812993L (fi) 1982-03-26
PT73728B (en) 1984-05-08
ES515033A0 (es) 1983-06-01
NO813248L (no) 1982-03-26
MC1423A1 (fr) 1982-10-18
FR2490675A1 (fr) 1982-03-26
MTP900B (en) 1985-02-28
DE3138096A1 (de) 1982-06-09
LU83648A1 (de) 1983-06-08

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