DD150749A5 - Verfahren zur herstellung von 11 beta-hydroxysteroiden der pregnanreihe - Google Patents

Verfahren zur herstellung von 11 beta-hydroxysteroiden der pregnanreihe Download PDF

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Publication number
DD150749A5
DD150749A5 DD79220600A DD22060079A DD150749A5 DD 150749 A5 DD150749 A5 DD 150749A5 DD 79220600 A DD79220600 A DD 79220600A DD 22060079 A DD22060079 A DD 22060079A DD 150749 A5 DD150749 A5 DD 150749A5
Authority
DD
German Democratic Republic
Prior art keywords
dione
hydroxy
pregnene
acetoxy
methoxymethoxy
Prior art date
Application number
DD79220600A
Other languages
German (de)
English (en)
Inventor
Ernst Schoettle
Alfred Weber
Mario Kennecke
Helmut Dahl
Joachim-Friedrich Kapp
Hans Wendt
Klaus Annen
Henry Laurent
Rudolf Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782803661 external-priority patent/DE2803661A1/de
Priority claimed from DE19782855465 external-priority patent/DE2855465A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DD150749A5 publication Critical patent/DD150749A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DD79220600A 1978-01-25 1979-01-23 Verfahren zur herstellung von 11 beta-hydroxysteroiden der pregnanreihe DD150749A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782803661 DE2803661A1 (de) 1978-01-25 1978-01-25 Neue in 17-position substituierte 11beta-hydroxysteroide der pregnanreihe, ihre herstellung und verwendung
DE19782855465 DE2855465A1 (de) 1978-12-19 1978-12-19 Neue kortikoide, verfahren zu ihrer herstellung, ihre verwendung und diese kortikoide enthaltende pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
DD150749A5 true DD150749A5 (de) 1981-09-16

Family

ID=25773724

Family Applications (2)

Application Number Title Priority Date Filing Date
DD79210595A DD141523A5 (de) 1978-01-25 1979-01-23 Verfahren zur herstellung von kortikoiden
DD79220600A DD150749A5 (de) 1978-01-25 1979-01-23 Verfahren zur herstellung von 11 beta-hydroxysteroiden der pregnanreihe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD79210595A DD141523A5 (de) 1978-01-25 1979-01-23 Verfahren zur herstellung von kortikoiden

Country Status (21)

Country Link
US (1) US4207316A (cs)
EP (1) EP0003341B1 (cs)
AU (1) AU529292B2 (cs)
BG (4) BG33736A3 (cs)
CS (1) CS207753B2 (cs)
DD (2) DD141523A5 (cs)
DE (1) DE2967070D1 (cs)
DK (1) DK28779A (cs)
EG (1) EG14273A (cs)
ES (1) ES477162A1 (cs)
FI (1) FI66023C (cs)
FR (1) FR2422689A1 (cs)
GB (1) GB2014150B (cs)
IE (1) IE47729B1 (cs)
IL (1) IL56494A (cs)
NO (1) NO154583C (cs)
NZ (1) NZ189460A (cs)
PH (1) PH18164A (cs)
PT (1) PT69126A (cs)
RO (2) RO81116A (cs)
SU (6) SU876059A3 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952003A1 (de) * 1979-12-21 1981-07-02 Schering Ag Berlin Und Bergkamen, 1000 Berlin Neue kortikoid-17-thioacetale, ihre herstellung und verwendung
DE3038855A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue d-homo-kortikoide, ihre herstellung und verwendung
CA2152374A1 (en) * 1993-01-08 1994-07-21 Ralph Lennart Brattsand Novel colon- or ileum-specific steroid derivatives
US5502222A (en) * 1994-06-01 1996-03-26 Schering Corporation Process for preparing delta 9,11 and 21-chloro corticosteroids
US8729108B2 (en) * 2008-06-17 2014-05-20 Christopher J Dannaker Waterborne topical compositions for the delivery of active ingredients such as azelaic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6682287D0 (pt) * 1965-08-30 1973-12-04 Merck & Co Inc Processo para preparar 17-alcoxi-progesteronas
NL6605514A (cs) * 1966-04-25 1967-10-26
US3453297A (en) * 1968-07-24 1969-07-01 Merck & Co Inc 17alpha-lower alkoxy-pregna-4,6-diene-3,20-dione steroids

Also Published As

Publication number Publication date
RO81116A (ro) 1983-06-01
US4207316A (en) 1980-06-10
FR2422689A1 (fr) 1979-11-09
AU4365779A (en) 1979-08-02
RO81116B (ro) 1983-05-30
NO154583C (no) 1986-11-05
NZ189460A (en) 1981-11-19
IL56494A (en) 1983-02-23
DK28779A (da) 1979-07-26
GB2014150B (en) 1982-11-24
PT69126A (de) 1979-02-01
PH18164A (en) 1985-04-09
SU876059A3 (ru) 1981-10-23
DD141523A5 (de) 1980-05-07
EP0003341A3 (en) 1979-08-22
BG33735A3 (bg) 1983-04-15
BG33738A3 (bg) 1983-04-15
FI790240A7 (fi) 1979-07-26
IE790134L (en) 1979-07-25
EG14273A (en) 1984-06-30
GB2014150A (en) 1979-08-22
IL56494A0 (en) 1979-03-12
RO76163A (ro) 1981-08-17
DE2967070D1 (en) 1984-08-02
SU876060A3 (ru) 1981-10-23
EP0003341A2 (de) 1979-08-08
SU890979A3 (ru) 1981-12-15
BG33736A3 (bg) 1983-04-15
IE47729B1 (en) 1984-05-30
EP0003341B1 (de) 1984-06-27
NO154583B (no) 1986-07-28
BG33737A3 (bg) 1983-04-15
NO790229L (no) 1979-07-26
FI66023C (fi) 1984-08-10
SU1103797A3 (ru) 1984-07-15
AU529292B2 (en) 1983-06-02
SU927123A3 (ru) 1982-05-07
SU880253A3 (ru) 1981-11-07
FI66023B (fi) 1984-04-30
ES477162A1 (es) 1979-07-01
CS207753B2 (en) 1981-08-31

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