DD141156A5 - Verfahren zur herstellung von 4a-aryl-octahydro-1h-2-pyrindinen - Google Patents

Verfahren zur herstellung von 4a-aryl-octahydro-1h-2-pyrindinen Download PDF

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Publication number
DD141156A5
DD141156A5 DD78210204A DD21020478A DD141156A5 DD 141156 A5 DD141156 A5 DD 141156A5 DD 78210204 A DD78210204 A DD 78210204A DD 21020478 A DD21020478 A DD 21020478A DD 141156 A5 DD141156 A5 DD 141156A5
Authority
DD
German Democratic Republic
Prior art keywords
group
carbon atoms
formula
hydrogen
compound
Prior art date
Application number
DD78210204A
Other languages
German (de)
English (en)
Inventor
Dennis M Zimmermann
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD141156A5 publication Critical patent/DD141156A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
DD78210204A 1977-12-27 1978-12-27 Verfahren zur herstellung von 4a-aryl-octahydro-1h-2-pyrindinen DD141156A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86489977A 1977-12-27 1977-12-27

Publications (1)

Publication Number Publication Date
DD141156A5 true DD141156A5 (de) 1980-04-16

Family

ID=25344312

Family Applications (1)

Application Number Title Priority Date Filing Date
DD78210204A DD141156A5 (de) 1977-12-27 1978-12-27 Verfahren zur herstellung von 4a-aryl-octahydro-1h-2-pyrindinen

Country Status (24)

Country Link
EP (1) EP0002937A1 (el)
JP (1) JPS5498770A (el)
AR (1) AR221352A1 (el)
AU (1) AU4286678A (el)
BE (1) BE872990A (el)
BG (1) BG30927A3 (el)
CA (1) CA1105026A (el)
CS (1) CS203940B2 (el)
DD (1) DD141156A5 (el)
DK (1) DK577078A (el)
ES (1) ES476385A1 (el)
FI (1) FI783992A (el)
FR (1) FR2413370A1 (el)
GB (1) GB2010806A (el)
GR (1) GR70349B (el)
IL (1) IL56268A0 (el)
IT (1) IT1101682B (el)
LU (1) LU80719A1 (el)
NZ (1) NZ189230A (el)
PL (1) PL117572B1 (el)
PT (1) PT68934A (el)
RO (1) RO75805A (el)
SU (1) SU841586A3 (el)
ZA (1) ZA787156B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415736A (en) * 1981-12-28 1983-11-15 E. I. Du Pont De Nemours & Co. Certain tetrahydropyridine intermediates
US4537963A (en) * 1981-12-28 1985-08-27 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-E]isoquinolines
US4579952A (en) * 1981-12-28 1986-04-01 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
CA2812526A1 (en) 2010-05-06 2011-11-10 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
AU2012212196B2 (en) 2011-02-02 2016-10-13 Vertex Pharmaceuticals Incorporated Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels
CA2827311A1 (en) 2011-02-18 2012-08-23 Vertex Pharmaceuticals Incorporated Chroman-spirocyclic piperidine amides as modulators of ion channels
CA2829803A1 (en) 2011-03-14 2012-09-20 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels
CA2917198C (en) * 2013-07-10 2022-06-07 Vertex Pharmaceuticals Incorporated Fused piperidine amides as modulators of ion channels

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2351599A1 (de) * 1972-07-20 1974-01-31 Du Pont 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung
AT330179B (de) * 1972-07-20 1976-06-25 Du Pont Verfahren zur herstellung von neuen 4a-aryl- transdecahydroisochinolinderivaten sowie deren optischen isomeren
PT67194B (en) * 1976-11-02 1979-03-23 Lilly Co Eli Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

Also Published As

Publication number Publication date
FI783992A (fi) 1979-06-28
PL117572B1 (en) 1981-08-31
CS203940B2 (en) 1981-03-31
PL211919A1 (pl) 1979-09-10
PT68934A (en) 1979-01-01
SU841586A3 (ru) 1981-06-23
GR70349B (el) 1982-09-23
NZ189230A (en) 1981-05-15
GB2010806A (en) 1979-07-04
JPS5498770A (en) 1979-08-03
AU4286678A (en) 1979-07-05
RO75805A (ro) 1981-02-28
ZA787156B (en) 1980-08-27
AR221352A1 (es) 1981-01-30
BE872990A (fr) 1979-06-22
LU80719A1 (fr) 1979-04-13
IL56268A0 (en) 1979-03-12
FR2413370A1 (fr) 1979-07-27
IT1101682B (it) 1985-10-07
CA1105026A (en) 1981-07-14
IT7831268A0 (it) 1978-12-22
EP0002937A1 (en) 1979-07-11
ES476385A1 (es) 1979-11-16
BG30927A3 (en) 1981-09-15
DK577078A (da) 1979-06-28

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