PT68934A - Process for preparing 4a-aryl-octahydro-1h-2-pyrindines - Google Patents

Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

Info

Publication number
PT68934A
PT68934A PT68934A PT6893478A PT68934A PT 68934 A PT68934 A PT 68934A PT 68934 A PT68934 A PT 68934A PT 6893478 A PT6893478 A PT 6893478A PT 68934 A PT68934 A PT 68934A
Authority
PT
Portugal
Prior art keywords
pyrindines
octahydro
aryl
preparing
Prior art date
Application number
PT68934A
Other languages
English (en)
Inventor
Dennis Michael Zimmernan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT68934A publication Critical patent/PT68934A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT68934A 1977-12-27 1978-12-19 Process for preparing 4a-aryl-octahydro-1h-2-pyrindines PT68934A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86489977A 1977-12-27 1977-12-27

Publications (1)

Publication Number Publication Date
PT68934A true PT68934A (en) 1979-01-01

Family

ID=25344312

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68934A PT68934A (en) 1977-12-27 1978-12-19 Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

Country Status (24)

Country Link
EP (1) EP0002937A1 (pt)
JP (1) JPS5498770A (pt)
AR (1) AR221352A1 (pt)
AU (1) AU4286678A (pt)
BE (1) BE872990A (pt)
BG (1) BG30927A3 (pt)
CA (1) CA1105026A (pt)
CS (1) CS203940B2 (pt)
DD (1) DD141156A5 (pt)
DK (1) DK577078A (pt)
ES (1) ES476385A1 (pt)
FI (1) FI783992A (pt)
FR (1) FR2413370A1 (pt)
GB (1) GB2010806A (pt)
GR (1) GR70349B (pt)
IL (1) IL56268A0 (pt)
IT (1) IT1101682B (pt)
LU (1) LU80719A1 (pt)
NZ (1) NZ189230A (pt)
PL (1) PL117572B1 (pt)
PT (1) PT68934A (pt)
RO (1) RO75805A (pt)
SU (1) SU841586A3 (pt)
ZA (1) ZA787156B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415736A (en) * 1981-12-28 1983-11-15 E. I. Du Pont De Nemours & Co. Certain tetrahydropyridine intermediates
US4537963A (en) * 1981-12-28 1985-08-27 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-E]isoquinolines
US4579952A (en) * 1981-12-28 1986-04-01 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
WO2011140425A1 (en) 2010-05-06 2011-11-10 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
AU2012212196B2 (en) 2011-02-02 2016-10-13 Vertex Pharmaceuticals Incorporated Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels
CA2827311A1 (en) 2011-02-18 2012-08-23 Vertex Pharmaceuticals Incorporated Chroman-spirocyclic piperidine amides as modulators of ion channels
CA2829803A1 (en) 2011-03-14 2012-09-20 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels
ES2780699T3 (es) * 2013-07-10 2020-08-26 Vertex Pharma Amidas de piperidina fusionadas útiles como moduladores de canales iónicos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2336559A1 (de) * 1972-07-20 1974-01-31 Du Pont 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung
AT330179B (de) * 1972-07-20 1976-06-25 Du Pont Verfahren zur herstellung von neuen 4a-aryl- transdecahydroisochinolinderivaten sowie deren optischen isomeren
PT67194B (en) * 1976-11-02 1979-03-23 Lilly Co Eli Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

Also Published As

Publication number Publication date
RO75805A (ro) 1981-02-28
GR70349B (pt) 1982-09-23
BG30927A3 (en) 1981-09-15
DD141156A5 (de) 1980-04-16
SU841586A3 (ru) 1981-06-23
LU80719A1 (fr) 1979-04-13
FI783992A (fi) 1979-06-28
IL56268A0 (en) 1979-03-12
ZA787156B (en) 1980-08-27
BE872990A (fr) 1979-06-22
PL117572B1 (en) 1981-08-31
JPS5498770A (en) 1979-08-03
FR2413370A1 (fr) 1979-07-27
EP0002937A1 (en) 1979-07-11
GB2010806A (en) 1979-07-04
CA1105026A (en) 1981-07-14
PL211919A1 (pl) 1979-09-10
AR221352A1 (es) 1981-01-30
IT7831268A0 (it) 1978-12-22
DK577078A (da) 1979-06-28
CS203940B2 (en) 1981-03-31
IT1101682B (it) 1985-10-07
ES476385A1 (es) 1979-11-16
NZ189230A (en) 1981-05-15
AU4286678A (en) 1979-07-05

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