IT7831268A0 - 4a-aril-ottaidro-piridine ad azione analgesica. - Google Patents
4a-aril-ottaidro-piridine ad azione analgesica.Info
- Publication number
- IT7831268A0 IT7831268A0 IT7831268A IT3126878A IT7831268A0 IT 7831268 A0 IT7831268 A0 IT 7831268A0 IT 7831268 A IT7831268 A IT 7831268A IT 3126878 A IT3126878 A IT 3126878A IT 7831268 A0 IT7831268 A0 IT 7831268A0
- Authority
- IT
- Italy
- Prior art keywords
- octahydropyridine
- aril
- analgesic action
- analgesic
- action
- Prior art date
Links
- 230000000202 analgesic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86489977A | 1977-12-27 | 1977-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7831268A0 true IT7831268A0 (it) | 1978-12-22 |
| IT1101682B IT1101682B (it) | 1985-10-07 |
Family
ID=25344312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT31268/78A IT1101682B (it) | 1977-12-27 | 1978-12-22 | 4a-aril-ottaidro-piridine ad azione analgesica |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0002937A1 (it) |
| JP (1) | JPS5498770A (it) |
| AR (1) | AR221352A1 (it) |
| AU (1) | AU4286678A (it) |
| BE (1) | BE872990A (it) |
| BG (1) | BG30927A3 (it) |
| CA (1) | CA1105026A (it) |
| CS (1) | CS203940B2 (it) |
| DD (1) | DD141156A5 (it) |
| DK (1) | DK577078A (it) |
| ES (1) | ES476385A1 (it) |
| FI (1) | FI783992A (it) |
| FR (1) | FR2413370A1 (it) |
| GB (1) | GB2010806A (it) |
| GR (1) | GR70349B (it) |
| IL (1) | IL56268A0 (it) |
| IT (1) | IT1101682B (it) |
| LU (1) | LU80719A1 (it) |
| NZ (1) | NZ189230A (it) |
| PL (1) | PL117572B1 (it) |
| PT (1) | PT68934A (it) |
| RO (1) | RO75805A (it) |
| SU (1) | SU841586A3 (it) |
| ZA (1) | ZA787156B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537963A (en) * | 1981-12-28 | 1985-08-27 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-E]isoquinolines |
| US4415736A (en) * | 1981-12-28 | 1983-11-15 | E. I. Du Pont De Nemours & Co. | Certain tetrahydropyridine intermediates |
| US4579952A (en) * | 1981-12-28 | 1986-04-01 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-e]isoquinolines |
| FR2617481B1 (fr) * | 1987-07-03 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| HUE028983T2 (en) | 2010-05-06 | 2017-01-30 | Vertex Pharma | Heterocyclic chromene-spirocyclic piperidine amides as ion channel modulators |
| EP3056495A1 (en) | 2011-02-02 | 2016-08-17 | Vertex Pharmaceuticals Inc. | Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels |
| US10385070B2 (en) | 2011-02-18 | 2019-08-20 | Vertex Pharmaceuticals Incorporated | Chroman-spirocyclic piperidine amides as modulators of ion channels |
| WO2012125613A1 (en) | 2011-03-14 | 2012-09-20 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
| WO2015006280A1 (en) * | 2013-07-10 | 2015-01-15 | Vertex Pharmaceuticals Incorporated | Fused piperidine amides as modulators of ion channels |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA734895B (en) * | 1972-07-20 | 1974-06-26 | Du Pont | Analgesigs and/or narcotic antagonists |
| CA1024149A (en) * | 1972-07-20 | 1978-01-10 | E.I. Du Pont De Nemours And Company | 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES |
| PT67194B (en) * | 1976-11-02 | 1979-03-23 | Lilly Co Eli | Process for preparing 4a-aryl-octahydro-1h-2-pyrindines |
-
1978
- 1978-12-19 NZ NZ189230A patent/NZ189230A/xx unknown
- 1978-12-19 PL PL1978211919A patent/PL117572B1/pl unknown
- 1978-12-19 BG BG041785A patent/BG30927A3/xx unknown
- 1978-12-19 PT PT68934A patent/PT68934A/pt unknown
- 1978-12-20 RO RO7895989A patent/RO75805A/ro unknown
- 1978-12-20 ZA ZA787156A patent/ZA787156B/xx unknown
- 1978-12-20 GR GR57949A patent/GR70349B/el unknown
- 1978-12-20 AR AR274886A patent/AR221352A1/es active
- 1978-12-20 CA CA318,284A patent/CA1105026A/en not_active Expired
- 1978-12-21 GB GB7849437A patent/GB2010806A/en not_active Withdrawn
- 1978-12-21 FR FR7835977A patent/FR2413370A1/fr not_active Withdrawn
- 1978-12-21 IL IL56268A patent/IL56268A0/xx unknown
- 1978-12-21 EP EP78300879A patent/EP0002937A1/en not_active Withdrawn
- 1978-12-22 AU AU42866/78A patent/AU4286678A/en active Pending
- 1978-12-22 DK DK577078A patent/DK577078A/da not_active Application Discontinuation
- 1978-12-22 BE BE1009211A patent/BE872990A/xx unknown
- 1978-12-22 CS CS788854A patent/CS203940B2/cs unknown
- 1978-12-22 LU LU80719A patent/LU80719A1/xx unknown
- 1978-12-22 IT IT31268/78A patent/IT1101682B/it active
- 1978-12-25 JP JP16448778A patent/JPS5498770A/ja active Pending
- 1978-12-26 SU SU782701053A patent/SU841586A3/ru active
- 1978-12-27 DD DD78210204A patent/DD141156A5/de unknown
- 1978-12-27 FI FI783992A patent/FI783992A/fi unknown
- 1978-12-27 ES ES476385A patent/ES476385A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DD141156A5 (de) | 1980-04-16 |
| AR221352A1 (es) | 1981-01-30 |
| LU80719A1 (fr) | 1979-04-13 |
| AU4286678A (en) | 1979-07-05 |
| CS203940B2 (en) | 1981-03-31 |
| ZA787156B (en) | 1980-08-27 |
| PT68934A (en) | 1979-01-01 |
| BE872990A (fr) | 1979-06-22 |
| BG30927A3 (en) | 1981-09-15 |
| EP0002937A1 (en) | 1979-07-11 |
| NZ189230A (en) | 1981-05-15 |
| DK577078A (da) | 1979-06-28 |
| PL117572B1 (en) | 1981-08-31 |
| CA1105026A (en) | 1981-07-14 |
| JPS5498770A (en) | 1979-08-03 |
| FR2413370A1 (fr) | 1979-07-27 |
| IT1101682B (it) | 1985-10-07 |
| ES476385A1 (es) | 1979-11-16 |
| GR70349B (it) | 1982-09-23 |
| RO75805A (ro) | 1981-02-28 |
| IL56268A0 (en) | 1979-03-12 |
| GB2010806A (en) | 1979-07-04 |
| SU841586A3 (ru) | 1981-06-23 |
| FI783992A (fi) | 1979-06-28 |
| PL211919A1 (pl) | 1979-09-10 |
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