BE872990A - Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique - Google Patents
Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutiqueInfo
- Publication number
- BE872990A BE872990A BE1009211A BE1009211A BE872990A BE 872990 A BE872990 A BE 872990A BE 1009211 A BE1009211 A BE 1009211A BE 1009211 A BE1009211 A BE 1009211A BE 872990 A BE872990 A BE 872990A
- Authority
- BE
- Belgium
- Prior art keywords
- pyrindins
- octahydro
- trans
- aryl
- therapeutic use
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86489977A | 1977-12-27 | 1977-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE872990A true BE872990A (fr) | 1979-06-22 |
Family
ID=25344312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1009211A BE872990A (fr) | 1977-12-27 | 1978-12-22 | Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0002937A1 (fr) |
JP (1) | JPS5498770A (fr) |
AR (1) | AR221352A1 (fr) |
AU (1) | AU4286678A (fr) |
BE (1) | BE872990A (fr) |
BG (1) | BG30927A3 (fr) |
CA (1) | CA1105026A (fr) |
CS (1) | CS203940B2 (fr) |
DD (1) | DD141156A5 (fr) |
DK (1) | DK577078A (fr) |
ES (1) | ES476385A1 (fr) |
FI (1) | FI783992A (fr) |
FR (1) | FR2413370A1 (fr) |
GB (1) | GB2010806A (fr) |
GR (1) | GR70349B (fr) |
IL (1) | IL56268A0 (fr) |
IT (1) | IT1101682B (fr) |
LU (1) | LU80719A1 (fr) |
NZ (1) | NZ189230A (fr) |
PL (1) | PL117572B1 (fr) |
PT (1) | PT68934A (fr) |
RO (1) | RO75805A (fr) |
SU (1) | SU841586A3 (fr) |
ZA (1) | ZA787156B (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4537963A (en) * | 1981-12-28 | 1985-08-27 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-E]isoquinolines |
US4415736A (en) * | 1981-12-28 | 1983-11-15 | E. I. Du Pont De Nemours & Co. | Certain tetrahydropyridine intermediates |
US4579952A (en) * | 1981-12-28 | 1986-04-01 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-e]isoquinolines |
FR2617481B1 (fr) * | 1987-07-03 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
HUE028983T2 (en) | 2010-05-06 | 2017-01-30 | Vertex Pharma | Heterocyclic chromene-spirocyclic piperidine amides as ion channel modulators |
EP3056495A1 (fr) | 2011-02-02 | 2016-08-17 | Vertex Pharmaceuticals Inc. | Amides pipéridines pyrrolopyrazine-spirocycliques en tant que modulateurs de canaux ioniques |
US10385070B2 (en) | 2011-02-18 | 2019-08-20 | Vertex Pharmaceuticals Incorporated | Chroman-spirocyclic piperidine amides as modulators of ion channels |
WO2012125613A1 (fr) | 2011-03-14 | 2012-09-20 | Vertex Pharmaceuticals Incorporated | Amides de pipéridine spirocycliques morpholines utilisés en tant que modulateurs de canaux ioniques |
WO2015006280A1 (fr) * | 2013-07-10 | 2015-01-15 | Vertex Pharmaceuticals Incorporated | Amides de pipéridine fusionnés utiles en tant que modulateurs de canaux ioniques |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA734895B (en) * | 1972-07-20 | 1974-06-26 | Du Pont | Analgesigs and/or narcotic antagonists |
CA1024149A (fr) * | 1972-07-20 | 1978-01-10 | E.I. Du Pont De Nemours And Company | 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES |
PT67194B (en) * | 1976-11-02 | 1979-03-23 | Lilly Co Eli | Process for preparing 4a-aryl-octahydro-1h-2-pyrindines |
-
1978
- 1978-12-19 NZ NZ189230A patent/NZ189230A/xx unknown
- 1978-12-19 PL PL1978211919A patent/PL117572B1/pl unknown
- 1978-12-19 BG BG041785A patent/BG30927A3/xx unknown
- 1978-12-19 PT PT68934A patent/PT68934A/pt unknown
- 1978-12-20 RO RO7895989A patent/RO75805A/fr unknown
- 1978-12-20 ZA ZA787156A patent/ZA787156B/xx unknown
- 1978-12-20 GR GR57949A patent/GR70349B/el unknown
- 1978-12-20 AR AR274886A patent/AR221352A1/es active
- 1978-12-20 CA CA318,284A patent/CA1105026A/fr not_active Expired
- 1978-12-21 GB GB7849437A patent/GB2010806A/en not_active Withdrawn
- 1978-12-21 FR FR7835977A patent/FR2413370A1/fr not_active Withdrawn
- 1978-12-21 IL IL56268A patent/IL56268A0/xx unknown
- 1978-12-21 EP EP78300879A patent/EP0002937A1/fr not_active Withdrawn
- 1978-12-22 AU AU42866/78A patent/AU4286678A/en active Pending
- 1978-12-22 DK DK577078A patent/DK577078A/da not_active Application Discontinuation
- 1978-12-22 BE BE1009211A patent/BE872990A/fr unknown
- 1978-12-22 CS CS788854A patent/CS203940B2/cs unknown
- 1978-12-22 LU LU80719A patent/LU80719A1/fr unknown
- 1978-12-22 IT IT31268/78A patent/IT1101682B/it active
- 1978-12-25 JP JP16448778A patent/JPS5498770A/ja active Pending
- 1978-12-26 SU SU782701053A patent/SU841586A3/ru active
- 1978-12-27 DD DD78210204A patent/DD141156A5/de unknown
- 1978-12-27 FI FI783992A patent/FI783992A/fi unknown
- 1978-12-27 ES ES476385A patent/ES476385A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DD141156A5 (de) | 1980-04-16 |
AR221352A1 (es) | 1981-01-30 |
LU80719A1 (fr) | 1979-04-13 |
AU4286678A (en) | 1979-07-05 |
CS203940B2 (en) | 1981-03-31 |
ZA787156B (en) | 1980-08-27 |
PT68934A (en) | 1979-01-01 |
BG30927A3 (en) | 1981-09-15 |
EP0002937A1 (fr) | 1979-07-11 |
NZ189230A (en) | 1981-05-15 |
DK577078A (da) | 1979-06-28 |
PL117572B1 (en) | 1981-08-31 |
CA1105026A (fr) | 1981-07-14 |
JPS5498770A (en) | 1979-08-03 |
FR2413370A1 (fr) | 1979-07-27 |
IT1101682B (it) | 1985-10-07 |
IT7831268A0 (it) | 1978-12-22 |
ES476385A1 (es) | 1979-11-16 |
GR70349B (fr) | 1982-09-23 |
RO75805A (fr) | 1981-02-28 |
IL56268A0 (en) | 1979-03-12 |
GB2010806A (en) | 1979-07-04 |
SU841586A3 (ru) | 1981-06-23 |
FI783992A (fi) | 1979-06-28 |
PL211919A1 (pl) | 1979-09-10 |
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