BE869959A - 2-1-benzisothiazoles, leur preparation et leur utilisation therapeutique - Google Patents

2-1-benzisothiazoles, leur preparation et leur utilisation therapeutique

Info

Publication number
BE869959A
BE869959A BE1009028A BE1009028A BE869959A BE 869959 A BE869959 A BE 869959A BE 1009028 A BE1009028 A BE 1009028A BE 1009028 A BE1009028 A BE 1009028A BE 869959 A BE869959 A BE 869959A
Authority
BE
Belgium
Prior art keywords
benzisothiazoles
preparation
therapeutic use
therapeutic
Prior art date
Application number
BE1009028A
Other languages
English (en)
Inventor
J A Carlson
M R Bell
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of BE869959A publication Critical patent/BE869959A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
BE1009028A 1977-05-04 1978-08-25 2-1-benzisothiazoles, leur preparation et leur utilisation therapeutique BE869959A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/793,629 US4112105A (en) 1977-05-04 1977-05-04 Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles

Publications (1)

Publication Number Publication Date
BE869959A true BE869959A (fr) 1979-02-26

Family

ID=25160405

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1009028A BE869959A (fr) 1977-05-04 1978-08-25 2-1-benzisothiazoles, leur preparation et leur utilisation therapeutique

Country Status (7)

Country Link
US (2) US4112105A (fr)
BE (1) BE869959A (fr)
DE (1) DE2837531A1 (fr)
FR (1) FR2434159A1 (fr)
GB (1) GB2030977B (fr)
LU (1) LU80161A1 (fr)
NL (1) NL7808844A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3170955A (en) * 1958-04-25 1965-02-23 Abbott Lab Amino and halogen substituted-n-diloweralkylamino-alkyl-benzamides
US3187001A (en) * 1963-07-22 1965-06-01 Parke Davis & Co Certain 2, 1-benzisothiazole compounds
DE1670907B2 (de) * 1967-08-16 1976-07-22 Bayer Ag, 5090 Leverkusen N-disubstituierte 3-amino-1,2benzisothiazole und verfahren in ihrer herstellung

Also Published As

Publication number Publication date
FR2434159B1 (fr) 1981-03-06
GB2030977A (en) 1980-04-16
NL7808844A (nl) 1980-03-03
US4152518A (en) 1979-05-01
US4112105A (en) 1978-09-05
FR2434159A1 (fr) 1980-03-21
DE2837531A1 (de) 1980-03-20
GB2030977B (en) 1983-05-11
LU80161A1 (fr) 1979-05-15

Similar Documents

Publication Publication Date Title
LU81439A1 (fr) Octahydro-pyrazolo(3,4-g)quinoleines et leur utilisation therapeutique
LU80619A1 (fr) Derives heterosidiques de pleuromutiline et leur utilisation therapeutique
LU81458A1 (fr) Phenethanolamines et leur utilisation therapeutique
LU80922A1 (fr) 9-amino-et imino-dibenzopyrannes et leur utilisation therapeutique
BE872886A (fr) Steroides, leur preparation et leur utilisation therapeutique
BE882601A (fr) Mercaptoacyldipeptides, leur preparation et leur utilisation
BE882166A (fr) 9-aminoalkylfluorenes, leur preparation et leur utilisation therapeutique
BE871807A (fr) 4-quinolyl-guanidines, leur preparation et leur utilisation
BE840797A (fr) Derives de (1-( , , -triallyakyl)4-phenyl-4-piperidine)methanols, leurpreparation et leur utilisation therapeutique
BE872134A (fr) Nouvelles indolo (2,3,a) quinolizidines, leur preparation et leur utilisation therapeutique
BE870196A (fr) Colorants, leur preparation et leur utilisation
BE863702A (fr) Tetrazolylcarbamoylquinoleines et leur preparation
LU80719A1 (fr) Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique
BE885117A (fr) 3-amino-oxazolidin-2-ones, leur preparation et leur utilisation
BE868953A (fr) Peptides, leur preparation et leur utilisation
BE866728A (fr) 1,2,4-triazoles, leur preparation et leur utilisation
BE871724A (fr) 4-desacetoxy-4 alpha-hydroxyindole-dihydroindoles et leur utilisation therapeutique
BE877328A (fr) Octahydro-2h-pyrrolo (3,4-g) quinoleines et leur utilisation therapeutique
LU81350A1 (fr) Arylalkyl-et aryloxyalkyl-phosphonates,leur preparation et leur utilisation therapeutique
BE869959A (fr) 2-1-benzisothiazoles, leur preparation et leur utilisation therapeutique
BE884990A (fr) Thiadiazine-amines, leur preparation et leur utilisation
BE882167A (fr) (1,1-biphenyl-2-yl)-propyl- et butylamines, leur preparation et leur utilisation therapeutique
BE880288A (fr) Hexahydro-2,6-methano-3-benzazocines, leur preparation et leur utilisation therapeutique
BE855591A (fr) Neoviridogriseines, leur preparation et leur utilisation
LU80474A1 (fr) 4-desacetoxy-4alpha-hydroxyindole-dihydroindoles,leur procede de preparation et leur utilisation therapeutique