DD129645A5 - Verfahren zur herstellung von neuen acetohydroxamsaeuren - Google Patents

Verfahren zur herstellung von neuen acetohydroxamsaeuren

Info

Publication number
DD129645A5
DD129645A5 DD7700198023A DD19802377A DD129645A5 DD 129645 A5 DD129645 A5 DD 129645A5 DD 7700198023 A DD7700198023 A DD 7700198023A DD 19802377 A DD19802377 A DD 19802377A DD 129645 A5 DD129645 A5 DD 129645A5
Authority
DD
German Democratic Republic
Prior art keywords
preparation
new
acetohydroxamic acids
acids
new acetohydroxamic
Prior art date
Application number
DD7700198023A
Other languages
German (de)
English (en)
Inventor
Louis Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of DD129645A5 publication Critical patent/DD129645A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/72—Acyl halides containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/56—Radicals substituted by sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
DD7700198023A 1976-03-23 1977-03-23 Verfahren zur herstellung von neuen acetohydroxamsaeuren DD129645A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB11710/76A GB1574822A (en) 1976-03-23 1976-03-23 Acetohydroxamic acid derivatives and pharmaceutical compositions thereof
GB629877 1977-02-15

Publications (1)

Publication Number Publication Date
DD129645A5 true DD129645A5 (de) 1978-02-01

Family

ID=26240593

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700198023A DD129645A5 (de) 1976-03-23 1977-03-23 Verfahren zur herstellung von neuen acetohydroxamsaeuren

Country Status (25)

Country Link
US (7) US4122186A (el)
JP (1) JPS52144601A (el)
AT (5) AT356078B (el)
AU (1) AU516473B2 (el)
BE (1) BE852738A (el)
CA (2) CA1120928A (el)
CH (1) CH620894A5 (el)
CS (1) CS200511B2 (el)
DD (1) DD129645A5 (el)
DE (1) DE2711451A1 (el)
DK (1) DK171197B1 (el)
ES (1) ES457105A1 (el)
FI (1) FI62821C (el)
FR (4) FR2345430A1 (el)
GB (1) GB1574822A (el)
IE (1) IE44721B1 (el)
IL (1) IL51705A (el)
LU (1) LU76989A1 (el)
NL (1) NL188801C (el)
NO (4) NO144420C (el)
NZ (1) NZ183616A (el)
PH (1) PH16271A (el)
PT (1) PT66300B (el)
SE (4) SE432420B (el)
SU (1) SU689617A3 (el)

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US4405357A (en) 1980-06-02 1983-09-20 Fmc Corporation Herbicidal 3-isoxazolidinones and hydroxamic acids
FR2502617B1 (el) * 1981-03-25 1984-04-27 Lafon Labor
FR2528041A1 (fr) * 1982-06-04 1983-12-09 Lafon Labor Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique
JPS59222454A (ja) * 1983-05-31 1984-12-14 Ajinomoto Co Inc アミノ酸の製造方法
US4604407A (en) * 1985-04-04 1986-08-05 E. R. Squibb & Sons, Inc. Hydroxamates
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FR2585699B1 (fr) * 1985-07-31 1988-03-11 Lafon Labor Derive d'acide acetohydroxamique, procede de preparation et utilisation en therapeutique
US5036157A (en) * 1986-03-11 1991-07-30 Burroughs Wellcome Co. Aryl derivatives
FR2601673B2 (fr) * 1986-07-21 1989-06-02 Lafon Labor Derives de l'acetamide et medicaments qui en contiennent
US4983567A (en) * 1987-03-16 1991-01-08 Biomeasure, Inc. Immunomodulators and methods of making same
ES2011588A6 (es) * 1989-05-29 1990-01-16 Vinas Lab Procedimiento para la preparacion de un nuevo derivado fenilacetico.
JPH0359402U (el) * 1989-10-13 1991-06-12
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US7842835B2 (en) * 2003-07-07 2010-11-30 Georgetown University Histone deacetylase inhibitors and methods of use thereof
WO2005007091A2 (en) * 2003-07-07 2005-01-27 Georgetown University Histone deacetylase inhibitors and methods of use thereof
US7417040B2 (en) * 2004-03-01 2008-08-26 Bristol-Myers Squibb Company Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US7378426B2 (en) * 2004-03-01 2008-05-27 Bristol-Myers Squibb Company Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US20090264384A1 (en) * 2004-11-01 2009-10-22 Nuada, Inc. Indole, benzimidazole, and benzolactam boronic acid compounds, analogs thereof and methods of use thereof
WO2007134169A2 (en) * 2006-05-10 2007-11-22 Nuada, Llc Indole, benzimidazole, and benzolactam boronic acid compounds, analogs thereof and methods of use thereof
WO2007113644A2 (en) * 2006-04-05 2007-10-11 Orchid Research Laboratories Limited New hdac inhibitors
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CN101528212A (zh) * 2006-09-28 2009-09-09 默克公司 Hdac抑制剂和可螯合的金属化合物的药物组合物以及金属-hdac抑制剂螯合物
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US8242174B2 (en) 2007-02-01 2012-08-14 Panthera Biopharma Llc Hydroxamic acid derivatives of aniline useful as therapeutic agents for treating anthrax poisoning
FR2957492B1 (fr) * 2010-03-18 2013-08-16 Rhodia Operations Nouvelles utilisations de composes de type esteramide
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DE1805548A1 (de) * 1968-10-26 1970-10-08 Agfa Gevaert Ag Benzimidazol-Derivate und ihre photographische Verwendung
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US4092430A (en) * 1970-09-09 1978-05-30 Ciba-Geigy Corporation Antiphlogistic phenylacetohydroxamic acid compositions
US3728380A (en) * 1971-05-17 1973-04-17 Morton Norwich Products Inc P-chlorobenzamidoacetohydroxamic acid
US3839580A (en) * 1972-08-14 1974-10-01 Morton Norwich Products Inc 2-p-(nitrobenzamido)acetohydroxamic for treating urinary tract infections
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Also Published As

Publication number Publication date
NO146431C (no) 1982-09-29
SE458605B (sv) 1989-04-17
LU76989A1 (el) 1977-07-18
US4225617A (en) 1980-09-30
CA1120928A (en) 1982-03-30
DK171197B1 (da) 1996-07-22
BE852738A (fr) 1977-09-22
NO152972C (no) 1985-12-27
NO803338L (no) 1977-09-26
FI62821B (fi) 1982-11-30
NO145881B (no) 1982-03-08
ATA839878A (de) 1980-09-15
FR2453133B1 (el) 1984-04-06
ES457105A1 (es) 1978-10-16
NO144420B (no) 1981-05-18
FR2453148A1 (fr) 1980-10-31
FR2453158B1 (el) 1982-08-06
DK126677A (da) 1977-09-24
NL188801C (nl) 1992-10-01
JPS628424B2 (el) 1987-02-23
ATA839978A (de) 1980-02-15
IL51705A0 (en) 1977-05-31
NO146431B (no) 1982-06-21
AT374191B (de) 1984-03-26
ATA193077A (de) 1979-09-15
ATA840078A (de) 1980-11-15
US4122186A (en) 1978-10-24
NO144420C (no) 1981-08-26
CH620894A5 (el) 1980-12-31
NO145881C (no) 1982-06-16
NL7703168A (nl) 1977-09-27
DE2711451A1 (de) 1977-10-06
PH16271A (en) 1983-08-25
ATA501480A (de) 1983-08-15
AT361932B (de) 1981-04-10
NZ183616A (en) 1979-03-28
AU516473B2 (en) 1981-06-04
NO803336L (no) 1977-09-26
NO803337L (no) 1977-09-26
FI770859A (el) 1977-09-24
FR2345430A1 (fr) 1977-10-21
NO771006L (no) 1977-09-26
SE8302171D0 (sv) 1983-04-19
PT66300A (fr) 1977-04-01
SE452155B (sv) 1987-11-16
IE44721B1 (en) 1982-03-10
AT362793B (de) 1981-06-10
AT356078B (de) 1980-04-10
AT358556B (de) 1980-09-25
SE8302173D0 (sv) 1983-04-19
PT66300B (pt) 1978-08-10
SE8302171L (sv) 1983-04-19
CA1130301A (en) 1982-08-24
US4152458A (en) 1979-05-01
SE432420B (sv) 1984-04-02
JPS52144601A (en) 1977-12-02
AU2334477A (en) 1978-09-21
DE2711451C2 (el) 1990-05-10
US4209524A (en) 1980-06-24
SE7703263L (sv) 1977-09-24
FI62821C (fi) 1983-03-10
SE8302173L (sv) 1983-04-19
SE8302172L (sv) 1983-04-19
SE8302172D0 (sv) 1983-04-19
FR2453133A1 (fr) 1980-10-31
SU689617A3 (ru) 1979-09-30
US4209523A (en) 1980-06-24
FR2453148B1 (el) 1983-12-02
CS200511B2 (en) 1980-09-15
US4151300A (en) 1979-04-24
US4183951A (en) 1980-01-15
FR2453158A1 (fr) 1980-10-31
IL51705A (en) 1982-09-30
GB1574822A (en) 1980-09-10
FR2345430B1 (el) 1982-07-23
NO152972B (no) 1985-09-16
IE44721L (en) 1977-09-23
SE456992B (sv) 1988-11-21

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