CZ213693A3 - Diindolepyrrolbenzodiazocines, process of their preparation and use, and a pharmaceutical mixture based thereon - Google Patents

Diindolepyrrolbenzodiazocines, process of their preparation and use, and a pharmaceutical mixture based thereon Download PDF

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Publication number
CZ213693A3
CZ213693A3 CS932136A CS213693A CZ213693A3 CZ 213693 A3 CZ213693 A3 CZ 213693A3 CS 932136 A CS932136 A CS 932136A CS 213693 A CS213693 A CS 213693A CZ 213693 A3 CZ213693 A3 CZ 213693A3
Authority
CZ
Czechia
Prior art keywords
compound
formula
give
water
mixture
Prior art date
Application number
CS932136A
Other languages
Czech (cs)
English (en)
Inventor
Stuart W Mccombie
Bandarpalle B Shankar
Michael P Kirkup
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CZ213693A3 publication Critical patent/CZ213693A3/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS932136A 1991-04-11 1992-04-09 Diindolepyrrolbenzodiazocines, process of their preparation and use, and a pharmaceutical mixture based thereon CZ213693A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68377091A 1991-04-11 1991-04-11
PCT/US1992/002661 WO1992018507A1 (en) 1991-04-11 1992-04-09 Anti-tumor and anti-psoriatic agents

Publications (1)

Publication Number Publication Date
CZ213693A3 true CZ213693A3 (en) 1994-05-18

Family

ID=24745378

Family Applications (1)

Application Number Title Priority Date Filing Date
CS932136A CZ213693A3 (en) 1991-04-11 1992-04-09 Diindolepyrrolbenzodiazocines, process of their preparation and use, and a pharmaceutical mixture based thereon

Country Status (14)

Country Link
EP (2) EP0508792A1 (enExample)
JP (1) JPH06503837A (enExample)
CA (1) CA2108146A1 (enExample)
CZ (1) CZ213693A3 (enExample)
FI (1) FI934461A7 (enExample)
HU (1) HUT70187A (enExample)
IE (1) IE921148A1 (enExample)
IL (1) IL101554A0 (enExample)
MX (1) MX9201643A (enExample)
NO (1) NO933611L (enExample)
NZ (1) NZ242294A (enExample)
SK (1) SK108293A3 (enExample)
TW (1) TW214553B (enExample)
WO (1) WO1992018507A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ245203A (en) * 1991-11-29 1997-07-27 Banyu Pharma Co Ltd 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates
EP0575955B1 (en) * 1992-06-22 1999-09-15 Kyowa Hakko Kogyo Co., Ltd. Process for producing staurosporine derivatives
WO1994007895A1 (en) * 1992-09-25 1994-04-14 Schering Corporation Diindolo compounds and pharmaceutical compositions containing them
US5843935A (en) * 1993-12-07 1998-12-01 Eli Lilly And Company Protein kinase C inhibitors
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
KR100340159B1 (ko) * 1993-12-07 2002-11-23 일라이 릴리 앤드 캄파니 단백질키나제c억제제
US5723456A (en) * 1993-12-07 1998-03-03 Eli Lilly & Company Therapeutic treatment for cardiovascular diseases
WO1995022331A1 (en) * 1994-02-18 1995-08-24 Cephalon, Inc. Aqueous indolocarbazole solutions
WO1997005140A1 (en) * 1995-07-31 1997-02-13 Novartis Ag Trindene compounds
US20040037828A1 (en) * 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
FR2826653B1 (fr) * 2001-06-29 2005-10-14 Servier Lab Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TW201041580A (en) 2001-09-27 2010-12-01 Alcon Inc Inhibitors of glycogen synthase kinase-3 (GSK-3) for treating glaucoma
ES2375565T3 (es) 2003-08-07 2012-03-02 Healor Ltd. Composiciones farmacéuticas y métodos para acelerar la cicatrización de heridas.
WO2007026356A2 (en) 2005-08-29 2007-03-08 Healor Ltd. Methods and compositions for prevention and treatment of diabetic and aged skin
EP2181999A1 (en) 2008-11-03 2010-05-05 Zentiva, A.S. Method of manufacturing ruboxistarin
EP2599494A1 (en) 2010-01-11 2013-06-05 Healor Ltd. PKC inhibitors for the treatment of inflammatory disease or disorder
JP2017524739A (ja) 2014-07-17 2017-08-31 アンセルムＩｎｓｅｒｍ 神経筋接合部関連疾患の処置方法
WO2016207366A1 (en) 2015-06-26 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of viral infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988007045A1 (fr) * 1987-03-09 1988-09-22 Kyowa Hakko Kogyo Co., Ltd. Derives de la substance physiologiquement active k-252
DE3924538A1 (de) * 1989-07-25 1991-01-31 Goedecke Ag Indolocarbazol und dessen verwendung

Also Published As

Publication number Publication date
JPH06503837A (ja) 1994-04-28
NO933611D0 (no) 1993-10-08
FI934461A0 (fi) 1993-10-11
SK108293A3 (en) 1994-09-07
FI934461L (fi) 1993-10-11
EP0508792A1 (en) 1992-10-14
HUT70187A (en) 1995-09-28
AU1798292A (en) 1992-11-17
TW214553B (enExample) 1993-10-11
NO933611L (no) 1993-10-08
IL101554A0 (en) 1992-12-30
MX9201643A (es) 1992-10-01
CA2108146A1 (en) 1992-10-12
NZ242294A (en) 1993-07-27
AU646163B2 (en) 1994-02-10
WO1992018507A1 (en) 1992-10-29
FI934461A7 (fi) 1993-10-11
HU9302869D0 (en) 1993-12-28
EP0580812A1 (en) 1994-02-02
IE921148A1 (en) 1992-10-21

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