HUT70187A - Process for preparing oxadiazepine derivatives condensed with indole and pharmaceutical compositions of anti-tumor and anti-psoriatic activity containing said compounds - Google Patents
Process for preparing oxadiazepine derivatives condensed with indole and pharmaceutical compositions of anti-tumor and anti-psoriatic activity containing said compounds Download PDFInfo
- Publication number
- HUT70187A HUT70187A HU9302869A HU9302869A HUT70187A HU T70187 A HUT70187 A HU T70187A HU 9302869 A HU9302869 A HU 9302869A HU 9302869 A HU9302869 A HU 9302869A HU T70187 A HUT70187 A HU T70187A
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- compound
- compounds
- water
- alkyl
- Prior art date
Links
- 0 CC(*)(C=C1)C=Cc2c1c1c3[n]2[C@@](C(*)(*)C2(*)*)O[C@@]2[n](c2c4C=C*(*)C=C2)c3c4c(*)c1* Chemical compound CC(*)(C=C1)C=Cc2c1c1c3[n]2[C@@](C(*)(*)C2(*)*)O[C@@]2[n](c2c4C=C*(*)C=C2)c3c4c(*)c1* 0.000 description 8
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68377091A | 1991-04-11 | 1991-04-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9302869D0 HU9302869D0 (en) | 1993-12-28 |
| HUT70187A true HUT70187A (en) | 1995-09-28 |
Family
ID=24745378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9302869A HUT70187A (en) | 1991-04-11 | 1992-04-09 | Process for preparing oxadiazepine derivatives condensed with indole and pharmaceutical compositions of anti-tumor and anti-psoriatic activity containing said compounds |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP0580812A1 (enExample) |
| JP (1) | JPH06503837A (enExample) |
| CA (1) | CA2108146A1 (enExample) |
| CZ (1) | CZ213693A3 (enExample) |
| FI (1) | FI934461L (enExample) |
| HU (1) | HUT70187A (enExample) |
| IE (1) | IE921148A1 (enExample) |
| IL (1) | IL101554A0 (enExample) |
| MX (1) | MX9201643A (enExample) |
| NO (1) | NO933611L (enExample) |
| NZ (1) | NZ242294A (enExample) |
| SK (1) | SK108293A3 (enExample) |
| TW (1) | TW214553B (enExample) |
| WO (1) | WO1992018507A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ245203A (en) * | 1991-11-29 | 1997-07-27 | Banyu Pharma Co Ltd | 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates |
| ES2136103T3 (es) * | 1992-06-22 | 1999-11-16 | Kyowa Hakko Kogyo Kk | Procedimiento para la preparacion de derivados de estaurosporina. |
| US5589472A (en) * | 1992-09-25 | 1996-12-31 | Vice; Susan F. | Diindolo compounds and pharmaceutical compositions containing them |
| US5624949A (en) * | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
| US5723456A (en) * | 1993-12-07 | 1998-03-03 | Eli Lilly & Company | Therapeutic treatment for cardiovascular diseases |
| PL182124B1 (pl) * | 1993-12-07 | 2001-11-30 | Lilly Co Eli | Nowe zwiazki oraz srodek farmaceutyczny przeznaczony do leczenia powiklan cukrzycowych lub do leczenia nowotworów PL PL PL PL PL PL PL PL |
| US5843935A (en) * | 1993-12-07 | 1998-12-01 | Eli Lilly And Company | Protein kinase C inhibitors |
| AU1911095A (en) * | 1994-02-18 | 1995-09-04 | Cephalon, Inc. | Aqueous indolocarbazole solutions |
| AU6657596A (en) * | 1995-07-31 | 1997-02-26 | Ciba-Geigy Ag | Trindene compounds |
| US20040037828A1 (en) * | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| FR2826653B1 (fr) * | 2001-06-29 | 2005-10-14 | Servier Lab | Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TWI335221B (en) | 2001-09-27 | 2011-01-01 | Alcon Inc | Inhibtors of glycogen synthase kinase-3 (gsk-3) for treating glaucoma |
| DK1651161T3 (da) | 2003-08-07 | 2012-01-30 | Healor Ltd | Farmaceutiske præparater og fremgangsmåder til at fremme sårheling |
| EP2452686A3 (en) | 2005-08-29 | 2012-09-05 | HealOr Ltd. | Methods and compositions for prevention and treatment of diabetic and aged skin |
| EP2181999A1 (en) | 2008-11-03 | 2010-05-05 | Zentiva, A.S. | Method of manufacturing ruboxistarin |
| EP2523677A2 (en) | 2010-01-11 | 2012-11-21 | Healor Ltd. | Method for treatment of inflammatory disease and disorder |
| EP3741375A1 (en) | 2014-07-17 | 2020-11-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for treating neuromuscular junction-related diseases |
| WO2016207366A1 (en) | 2015-06-26 | 2016-12-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of viral infections |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923986A (en) * | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
| DE3924538A1 (de) * | 1989-07-25 | 1991-01-31 | Goedecke Ag | Indolocarbazol und dessen verwendung |
-
1992
- 1992-04-09 SK SK1082-93A patent/SK108293A3/sk unknown
- 1992-04-09 JP JP4510240A patent/JPH06503837A/ja active Pending
- 1992-04-09 EP EP92917468A patent/EP0580812A1/en active Pending
- 1992-04-09 HU HU9302869A patent/HUT70187A/hu unknown
- 1992-04-09 CZ CS932136A patent/CZ213693A3/cs unknown
- 1992-04-09 FI FI934461A patent/FI934461L/fi not_active Application Discontinuation
- 1992-04-09 MX MX9201643A patent/MX9201643A/es unknown
- 1992-04-09 IL IL101554A patent/IL101554A0/xx unknown
- 1992-04-09 EP EP92303187A patent/EP0508792A1/en not_active Withdrawn
- 1992-04-09 WO PCT/US1992/002661 patent/WO1992018507A1/en not_active Ceased
- 1992-04-09 CA CA002108146A patent/CA2108146A1/en not_active Abandoned
- 1992-04-09 NZ NZ242294A patent/NZ242294A/en unknown
- 1992-04-09 TW TW081102729A patent/TW214553B/zh active
- 1992-04-10 IE IE114892A patent/IE921148A1/en unknown
-
1993
- 1993-10-08 NO NO93933611A patent/NO933611L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06503837A (ja) | 1994-04-28 |
| NZ242294A (en) | 1993-07-27 |
| NO933611D0 (no) | 1993-10-08 |
| CZ213693A3 (en) | 1994-05-18 |
| EP0580812A1 (en) | 1994-02-02 |
| AU1798292A (en) | 1992-11-17 |
| FI934461A0 (fi) | 1993-10-11 |
| WO1992018507A1 (en) | 1992-10-29 |
| IL101554A0 (en) | 1992-12-30 |
| EP0508792A1 (en) | 1992-10-14 |
| SK108293A3 (en) | 1994-09-07 |
| FI934461A7 (fi) | 1993-10-11 |
| NO933611L (no) | 1993-10-08 |
| IE921148A1 (en) | 1992-10-21 |
| CA2108146A1 (en) | 1992-10-12 |
| MX9201643A (es) | 1992-10-01 |
| HU9302869D0 (en) | 1993-12-28 |
| AU646163B2 (en) | 1994-02-10 |
| TW214553B (enExample) | 1993-10-11 |
| FI934461L (fi) | 1993-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP4198037A1 (en) | Macrocycles as modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions thereof and their use in the treatment of cycstic fibrosis | |
| AU721037B2 (en) | Condensed N-acylindoles as antitumor agents | |
| BR112016011851B1 (pt) | Derivados de imidazol e pirazol fundidos como moduladores de atividade de tnf | |
| EP3362454B1 (en) | Ep4 antagonists | |
| EP3068785A1 (en) | Substituted 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine derivatives as casein kinase 1 d/e inhibitors | |
| TW202024037A (zh) | 用於治療特定白血病之化合物 | |
| WO2011009898A1 (en) | Fused aminodihydro-oxazine derivatives | |
| SK108293A3 (en) | Anti-tumor and anti-psoriatic agents | |
| EP4364804A2 (en) | Inhibitors of keap1-nrf2 protein-protein interaction | |
| EP4137484A1 (en) | Tricyclic compounds as egfr inhibitors | |
| JP2021501184A (ja) | Ｐ２ｘ３及び／又はｐ２ｘ２／３受容体アンタゴニスト、それを含む医薬組成物及びその使用 | |
| EP4628486A1 (en) | Amide or urea compound | |
| US5786486A (en) | Acrylamide derivatives and process for production thereof | |
| US5589472A (en) | Diindolo compounds and pharmaceutical compositions containing them | |
| JP5662940B2 (ja) | 新規な抗微生物薬 | |
| EP0424802A2 (en) | Tricyclic quinoline antineoplastic agents | |
| AU2003217373B2 (en) | Novel tyloindicines and related processes, pharmaceutical compositions and methods | |
| EP1979352A2 (fr) | Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique. | |
| WO2019108943A1 (en) | Benzene fused heterocyclic compound and use thereof | |
| EP4144741B1 (en) | Pyrimidine-based tricyclic compound and use thereof | |
| HU223948B1 (hu) | Metotrexát-származékok, ilyeneket tartalmazó gyógyszerkészítmények és eljárás előállításukra | |
| HUP0200376A2 (en) | Thiaoloindolinone compounds, process for their preparation and pharmaceutical composions containing them and their use | |
| JP2022524294A (ja) | デュオカルマイシン類似体 | |
| EP2066677B1 (en) | Pyridooxazepine progesteron receptor modulators | |
| EP3915977A1 (en) | 1,2,3,4-tetrahydroquinoxaline derivative, preparation method therefor and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFD9 | Temporary protection cancelled due to non-payment of fee |