CZ200537A3 - Systémy pro difusní rízenou dodávku léciva obsahující fluorsiloxanovou matrici - Google Patents

Systémy pro difusní rízenou dodávku léciva obsahující fluorsiloxanovou matrici Download PDF

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Publication number
CZ200537A3
CZ200537A3 CZ20050037A CZ200537A CZ200537A3 CZ 200537 A3 CZ200537 A3 CZ 200537A3 CZ 20050037 A CZ20050037 A CZ 20050037A CZ 200537 A CZ200537 A CZ 200537A CZ 200537 A3 CZ200537 A3 CZ 200537A3
Authority
CZ
Czechia
Prior art keywords
methacrylate
agents
drug delivery
group
controlled diffusion
Prior art date
Application number
CZ20050037A
Other languages
Czech (cs)
English (en)
Inventor
C. Salamone@Joseph
F. Kunzler@Jay
M. Ammon@Daniel
Original Assignee
Bausch & Lomb Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb Incorporated filed Critical Bausch & Lomb Incorporated
Publication of CZ200537A3 publication Critical patent/CZ200537A3/cs

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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04Polysiloxanes
    • C08G77/22Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/24Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen halogen-containing groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/04Polysiloxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04Polysiloxanes
    • C08G77/14Polysiloxanes containing silicon bound to oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04Polysiloxanes
    • C08G77/20Polysiloxanes containing silicon bound to unsaturated aliphatic groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42Block-or graft-polymers containing polysiloxane sequences
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/70Siloxanes defined by use of the MDTQ nomenclature

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CZ20050037A 2002-06-19 2003-06-16 Systémy pro difusní rízenou dodávku léciva obsahující fluorsiloxanovou matrici CZ200537A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/175,716 US20040043067A1 (en) 2002-06-19 2002-06-19 Fluorosiloxane matrix controlled diffusion drug delivery systems

Publications (1)

Publication Number Publication Date
CZ200537A3 true CZ200537A3 (cs) 2006-04-12

Family

ID=29999052

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20050037A CZ200537A3 (cs) 2002-06-19 2003-06-16 Systémy pro difusní rízenou dodávku léciva obsahující fluorsiloxanovou matrici

Country Status (17)

Country Link
US (1) US20040043067A1 (enExample)
EP (1) EP1515705B1 (enExample)
JP (1) JP2005530842A (enExample)
CN (1) CN1662227A (enExample)
AU (1) AU2003238247A1 (enExample)
BR (1) BR0311963A (enExample)
CA (1) CA2489987A1 (enExample)
CZ (1) CZ200537A3 (enExample)
DE (1) DE60306379T2 (enExample)
ES (1) ES2261947T3 (enExample)
MX (1) MXPA04012897A (enExample)
PL (1) PL375000A1 (enExample)
RU (1) RU2307667C2 (enExample)
TW (1) TW200404569A (enExample)
UA (1) UA80433C2 (enExample)
WO (1) WO2004000288A1 (enExample)
ZA (1) ZA200409979B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008504938A (ja) 2004-07-02 2008-02-21 レイザー,エリオット 治療媒体送出装置およびその送出装置を用いて治療媒体を眼に送り出す方法
US7544371B2 (en) * 2005-12-20 2009-06-09 Bausch + Lomb Incorporated Drug delivery systems
US20070148244A1 (en) * 2005-12-22 2007-06-28 Kunzler Jay F Drug delivery systems
US20070218103A1 (en) * 2006-03-15 2007-09-20 Bausch & Lomb Incorporated Rate controlled release of a pharmaceutical agent in a biodegradable device
US20070218104A1 (en) * 2006-03-15 2007-09-20 Bausch & Lomb Incorporation Rate controlled release of a pharmaceutical agent in a biodegradable device
ES2717607T3 (es) 2006-03-31 2019-06-24 Mati Therapeutics Inc Estructuras de administración de fármacos y composiciones para el sistema nasolagrimal
US7579021B2 (en) * 2006-09-27 2009-08-25 Bausch & Lomb Incorporated Drug delivery systems based on degradable cationic siloxanyl macromonomers
UY30883A1 (es) * 2007-01-31 2008-05-31 Alcon Res Tapones punctales y metodos de liberacion de agentes terapeuticos
NZ583858A (en) 2007-09-07 2012-08-31 Quadra Logic Tech Inc Lacrimal implant detection with detection device
WO2009043174A1 (en) * 2007-10-05 2009-04-09 Interface Biologics Inc. Oligofluorinated cross-linked polymers and uses thereof
WO2010085696A2 (en) * 2009-01-23 2010-07-29 Qlt Plug Delivery Inc. Sustained released delivery of one or more agents
CN107669399B (zh) 2011-08-29 2019-11-19 麦提疗法有限公司 持续释放递送活性剂以治疗青光眼和高眼压
US9974685B2 (en) 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
CA1295941C (en) * 1985-08-16 1992-02-18 Rajan Bawa Sustained-release formulation comprising a hydrophobic polymer system
IL91398A (en) * 1988-08-30 1994-05-30 Pfizer Pharmaceutical delivery device comprising active substance surrounded by asymmetric membrane
US4882377A (en) * 1988-09-21 1989-11-21 Dow Corning Corporation Low-viscosity pressure-adherent silicone elastomer compositions
US5321108A (en) * 1993-02-12 1994-06-14 Bausch & Lomb Incorporated Fluorosilicone hydrogels
US5463010A (en) * 1993-11-12 1995-10-31 Surface Engineering Technologies, Division Of Innerdyne, Inc. Hydrocyclosiloxane membrane prepared by plasma polymerization process
US6322815B1 (en) * 1994-07-22 2001-11-27 W. Mark Saltzman Multipart drug delivery system
US5714557A (en) * 1995-12-07 1998-02-03 Bausch & Lomb Incorporated Monomeric units useful for reducing the modulus of low water polymeric silicone compositions
CN1084335C (zh) * 1995-12-07 2002-05-08 博士伦公司 用于降低硅氧烷水凝胶的模量的单体单元
US6296873B1 (en) * 1997-01-23 2001-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Zero-order sustained release delivery system for carbamazephine derivatives
NZ500649A (en) * 1997-04-03 2001-05-25 Guilford Pharm Inc Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, articles, and methods for making a biosorbable suture, an orthopedic appliance or bone cement for repairing injuries to bone or connective tissue
US5908996A (en) * 1997-10-24 1999-06-01 Timewarp Technologies Ltd Device for controlling a musical performance
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
TW200800298A (en) * 2000-01-27 2008-01-01 Zentaris Ag Compressed microparticles for dry injection

Also Published As

Publication number Publication date
ZA200409979B (en) 2006-07-26
MXPA04012897A (es) 2005-03-31
UA80433C2 (en) 2007-09-25
TW200404569A (en) 2004-04-01
HK1070826A1 (en) 2005-06-30
JP2005530842A (ja) 2005-10-13
BR0311963A (pt) 2005-03-29
US20040043067A1 (en) 2004-03-04
CA2489987A1 (en) 2003-12-31
PL375000A1 (en) 2005-11-14
EP1515705A1 (en) 2005-03-23
EP1515705B1 (en) 2006-06-21
CN1662227A (zh) 2005-08-31
ES2261947T3 (es) 2006-11-16
RU2307667C2 (ru) 2007-10-10
DE60306379T2 (de) 2007-06-14
WO2004000288A1 (en) 2003-12-31
AU2003238247A1 (en) 2004-01-06
DE60306379D1 (de) 2006-08-03
RU2005100840A (ru) 2005-07-10

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