CZ20022932A3 - Antagonisté IL-8 receptoru - Google Patents

Antagonisté IL-8 receptoru Download PDF

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Publication number
CZ20022932A3
CZ20022932A3 CZ20022932A CZ20022932A CZ20022932A3 CZ 20022932 A3 CZ20022932 A3 CZ 20022932A3 CZ 20022932 A CZ20022932 A CZ 20022932A CZ 20022932 A CZ20022932 A CZ 20022932A CZ 20022932 A3 CZ20022932 A3 CZ 20022932A3
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CZ
Czechia
Prior art keywords
alkyl
arylc
heteroaryl
optionally substituted
alkenyl
Prior art date
Application number
CZ20022932A
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Czech (cs)
English (en)
Inventor
Michael Robert Palovich
Joseph Weinstock
Katherine Lousia Widdowson
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of CZ20022932A3 publication Critical patent/CZ20022932A3/cs

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    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
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  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
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CZ20022932A 2000-03-01 2001-03-01 Antagonisté IL-8 receptoru CZ20022932A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18618300P 2000-03-01 2000-03-01

Publications (1)

Publication Number Publication Date
CZ20022932A3 true CZ20022932A3 (cs) 2003-05-14

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ID=22683958

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20022932A CZ20022932A3 (cs) 2000-03-01 2001-03-01 Antagonisté IL-8 receptoru

Country Status (28)

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EP (1) EP1261328B1 (es)
JP (1) JP2003525242A (es)
KR (1) KR20020080460A (es)
CN (1) CN1416339A (es)
AP (1) AP2002002605A0 (es)
AR (1) AR033803A1 (es)
AT (1) ATE299698T1 (es)
AU (1) AU2001239970A1 (es)
BG (1) BG107014A (es)
BR (1) BR0108866A (es)
CA (1) CA2401659A1 (es)
CZ (1) CZ20022932A3 (es)
DE (1) DE60112051T2 (es)
DZ (1) DZ3309A1 (es)
EA (1) EA200200933A1 (es)
ES (1) ES2245976T3 (es)
HU (1) HUP0300599A3 (es)
IL (1) IL151429A0 (es)
MA (1) MA25657A1 (es)
MX (1) MXPA02008589A (es)
NO (1) NO20024133L (es)
OA (1) OA12184A (es)
PE (1) PE20011190A1 (es)
PL (1) PL358540A1 (es)
SK (1) SK12352002A3 (es)
UY (1) UY26601A1 (es)
WO (1) WO2001064208A1 (es)
ZA (1) ZA200206988B (es)

Families Citing this family (18)

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Publication number Priority date Publication date Assignee Title
EP1284956A4 (en) * 2000-05-30 2005-08-24 Smithkline Beecham Corp ANTAGONISTS OF THE IL-8 RECEPTOR
US20040132694A1 (en) * 2001-01-16 2004-07-08 Palovich Michael R. Il-8 receptor antagonists
IL156793A0 (en) * 2001-02-02 2004-02-08 Schering Corp 3,4-di-substituted cyclobutene-1,2-diones as cxc chemokine receptor antagonists
US7132445B2 (en) 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
MY149050A (en) * 2001-04-16 2013-07-15 Merck Sharp & Dohme 3,4 di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands
US20040106794A1 (en) 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
EP1434775A1 (en) 2001-10-12 2004-07-07 Schering Corporation 3,4-di-substituted maleimide compounds as cxc-chemokine receptor antagonists
US6878709B2 (en) 2002-01-04 2005-04-12 Schering Corporation 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists
WO2003080053A1 (en) 2002-03-18 2003-10-02 Schering Corporation Combination treatments for chemokine-mediated diseases
PE20040570A1 (es) * 2002-10-09 2004-08-30 Pharmacopeia Drug Discovery Tiadiazoldioxidos y tiadiazoloxidos como ligandos del receptor de cxc- y cc-quimiocina
ATE406356T1 (de) * 2003-12-19 2008-09-15 Schering Corp Thiadiazole als cxc- und cc- chemokinrezeptorliganden
WO2005068460A1 (en) * 2003-12-22 2005-07-28 Schering Corporation Isothiazole dioxides as cxc- and cc- chemokine receptor ligands
ES2353401T3 (es) 2005-06-29 2011-03-01 Schering Corporation Oxidiazolopirazinas y tiadiazolopirazinas 5,6-di-sustituidas como ligandos del receptor de cxc-quimiocina.
MX2008000366A (es) 2005-06-29 2008-03-07 Schering Corp Oxadiazoles di-sustituidos como ligandos del receptor cxc-quimiocina.
TWI724056B (zh) 2015-11-19 2021-04-11 美商卡默森屈有限公司 Ｃｘｃｒ２抑制劑
TWI734715B (zh) 2015-11-19 2021-08-01 美商卡默森屈有限公司 趨化因子受體調節劑
EP3737366A4 (en) 2018-01-08 2022-07-27 ChemoCentryx, Inc. METHOD OF TREATMENT OF GENERALIZED PUSTULOUS PSORIASIS WITH AN ANTAGONIST OF CCR6 OR CXCR2
CN112851635B (zh) * 2019-11-28 2022-09-16 中国医学科学院药物研究所 环状砜类化合物及其制备方法、用途和药物组合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780483A (en) * 1995-02-17 1998-07-14 Smithkline Beecham Corporation IL-8 receptor antagonists

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DZ3309A1 (en) 2001-09-07
CN1416339A (zh) 2003-05-07
DE60112051D1 (de) 2005-08-25
AP2002002605A0 (en) 2002-09-30
NO20024133L (no) 2002-10-31
PL358540A1 (en) 2004-08-09
MXPA02008589A (es) 2003-02-24
JP2003525242A (ja) 2003-08-26
ES2245976T3 (es) 2006-02-01
EP1261328A1 (en) 2002-12-04
BR0108866A (pt) 2004-02-25
HUP0300599A2 (hu) 2003-07-28
EP1261328A4 (en) 2003-05-28
EP1261328B1 (en) 2005-07-20
AU2001239970A1 (en) 2001-09-12
DE60112051T2 (de) 2006-04-27
UY26601A1 (es) 2001-08-27
EA200200933A1 (ru) 2003-02-27
SK12352002A3 (sk) 2003-02-04
WO2001064208A1 (en) 2001-09-07
ATE299698T1 (de) 2005-08-15
OA12184A (en) 2006-05-09
BG107014A (bg) 2003-05-30
IL151429A0 (en) 2003-04-10
MA25657A1 (fr) 2002-12-31
AR033803A1 (es) 2004-01-07
CA2401659A1 (en) 2001-09-07
KR20020080460A (ko) 2002-10-23
HUP0300599A3 (en) 2003-09-29
NO20024133D0 (no) 2002-08-30
ZA200206988B (en) 2003-10-16
PE20011190A1 (es) 2002-01-06

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