UY26601A1 - Antagonistas de los receptores de il-8 - Google Patents

Antagonistas de los receptores de il-8

Info

Publication number
UY26601A1
UY26601A1 UY26601A UY26601A UY26601A1 UY 26601 A1 UY26601 A1 UY 26601A1 UY 26601 A UY26601 A UY 26601A UY 26601 A UY26601 A UY 26601A UY 26601 A1 UY26601 A1 UY 26601A1
Authority
UY
Uruguay
Prior art keywords
receptor antagonists
squarates
dianilino
treatment
relates
Prior art date
Application number
UY26601A
Other languages
English (en)
Inventor
Michael Robert Palovich
Katherine Widdowson
Joseph Weinstock
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of UY26601A1 publication Critical patent/UY26601A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)

Abstract

Esta invención se refiere al nuevo uso de dianilino escuaratos en el tratamiento de estados de enfermedades mediados por la quimioquina interleuquina-8 (IL-8).
UY26601A 2000-03-01 2001-03-01 Antagonistas de los receptores de il-8 UY26601A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18618300P 2000-03-01 2000-03-01

Publications (1)

Publication Number Publication Date
UY26601A1 true UY26601A1 (es) 2001-08-27

Family

ID=22683958

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26601A UY26601A1 (es) 2000-03-01 2001-03-01 Antagonistas de los receptores de il-8

Country Status (28)

Country Link
EP (1) EP1261328B1 (es)
JP (1) JP2003525242A (es)
KR (1) KR20020080460A (es)
CN (1) CN1416339A (es)
AP (1) AP2002002605A0 (es)
AR (1) AR033803A1 (es)
AT (1) ATE299698T1 (es)
AU (1) AU2001239970A1 (es)
BG (1) BG107014A (es)
BR (1) BR0108866A (es)
CA (1) CA2401659A1 (es)
CZ (1) CZ20022932A3 (es)
DE (1) DE60112051T2 (es)
DZ (1) DZ3309A1 (es)
EA (1) EA200200933A1 (es)
ES (1) ES2245976T3 (es)
HU (1) HUP0300599A3 (es)
IL (1) IL151429A0 (es)
MA (1) MA25657A1 (es)
MX (1) MXPA02008589A (es)
NO (1) NO20024133L (es)
OA (1) OA12184A (es)
PE (1) PE20011190A1 (es)
PL (1) PL358540A1 (es)
SK (1) SK12352002A3 (es)
UY (1) UY26601A1 (es)
WO (1) WO2001064208A1 (es)
ZA (1) ZA200206988B (es)

Families Citing this family (18)

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Publication number Priority date Publication date Assignee Title
HUP0302382A3 (en) * 2000-05-30 2004-09-28 Smithkline Beecham Corp Il-8 receptor antagonists and pharmaceutical compositions containing them
ATE419845T1 (de) * 2001-01-16 2009-01-15 Smithkline Beecham Corp Il-8-rezeptor-antagonisten
KR20030090629A (ko) * 2001-02-02 2003-11-28 쉐링 코포레이션 Ｃｘｃ 케모카인 수용체 길항제로서의 3,4-디-치환된사이클로부텐-1,2-디온
US7132445B2 (en) 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
EP1381590B1 (en) * 2001-04-16 2007-06-20 Schering Corporation 3,4-di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands
US20040106794A1 (en) 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
WO2003031440A1 (en) * 2001-10-12 2003-04-17 Schering Corporation 3,4-di-substituted maleimide compounds as cxc-chemokine receptor antagonists
US6878709B2 (en) 2002-01-04 2005-04-12 Schering Corporation 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists
BR0308739A (pt) * 2002-03-18 2005-01-11 Schering Corp Tratamentos em combinação para doenças mediadas por quimiocina
WO2004033440A1 (en) 2002-10-09 2004-04-22 Schering Corporation Thiadiazoledioxides and thiadiazoleoxides as cxc- and cc-chemokine receptor ligands
DE602004016211D1 (en) 2003-12-19 2008-10-09 Schering Corp Thiadiazole als cxc- und cc-chemokinrezeptorliganden
MXPA06007205A (es) * 2003-12-22 2006-08-31 Schering Corp Dioxidos de isotiazol como ligandos del receptor cxc y cc-quimiocina.
ES2353401T3 (es) 2005-06-29 2011-03-01 Schering Corporation Oxidiazolopirazinas y tiadiazolopirazinas 5,6-di-sustituidas como ligandos del receptor de cxc-quimiocina.
MX2008000366A (es) 2005-06-29 2008-03-07 Schering Corp Oxadiazoles di-sustituidos como ligandos del receptor cxc-quimiocina.
TWI724056B (zh) 2015-11-19 2021-04-11 美商卡默森屈有限公司 Ｃｘｃｒ２抑制劑
TWI734715B (zh) 2015-11-19 2021-08-01 美商卡默森屈有限公司 趨化因子受體調節劑
US11207294B2 (en) 2018-01-08 2021-12-28 Chemocentryx, Inc. Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2
CN112851635B (zh) * 2019-11-28 2022-09-16 中国医学科学院药物研究所 环状砜类化合物及其制备方法、用途和药物组合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780483A (en) * 1995-02-17 1998-07-14 Smithkline Beecham Corporation IL-8 receptor antagonists

Also Published As

Publication number Publication date
MXPA02008589A (es) 2003-02-24
WO2001064208A1 (en) 2001-09-07
DE60112051T2 (de) 2006-04-27
HUP0300599A3 (en) 2003-09-29
BG107014A (bg) 2003-05-30
EP1261328B1 (en) 2005-07-20
EA200200933A1 (ru) 2003-02-27
NO20024133L (no) 2002-10-31
DZ3309A1 (en) 2001-09-07
CZ20022932A3 (cs) 2003-05-14
OA12184A (en) 2006-05-09
HUP0300599A2 (hu) 2003-07-28
CA2401659A1 (en) 2001-09-07
AP2002002605A0 (en) 2002-09-30
JP2003525242A (ja) 2003-08-26
ZA200206988B (en) 2003-10-16
EP1261328A1 (en) 2002-12-04
AR033803A1 (es) 2004-01-07
ES2245976T3 (es) 2006-02-01
EP1261328A4 (en) 2003-05-28
NO20024133D0 (no) 2002-08-30
BR0108866A (pt) 2004-02-25
AU2001239970A1 (en) 2001-09-12
KR20020080460A (ko) 2002-10-23
IL151429A0 (en) 2003-04-10
PL358540A1 (en) 2004-08-09
ATE299698T1 (de) 2005-08-15
SK12352002A3 (sk) 2003-02-04
PE20011190A1 (es) 2002-01-06
DE60112051D1 (de) 2005-08-25
MA25657A1 (fr) 2002-12-31
CN1416339A (zh) 2003-05-07

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