CZ20012713A3 - Způsob přípravy pyrazol[4,3-d]pyrimidin-7-onových sloučenin a jejich meziprodukty - Google Patents

Způsob přípravy pyrazol[4,3-d]pyrimidin-7-onových sloučenin a jejich meziprodukty Download PDF

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Publication number
CZ20012713A3
CZ20012713A3 CZ20012713A CZ20012713A CZ20012713A3 CZ 20012713 A3 CZ20012713 A3 CZ 20012713A3 CZ 20012713 A CZ20012713 A CZ 20012713A CZ 20012713 A CZ20012713 A CZ 20012713A CZ 20012713 A3 CZ20012713 A3 CZ 20012713A3
Authority
CZ
Czechia
Prior art keywords
lower alkyl
group
formula
compound
halogen
Prior art date
Application number
CZ20012713A
Other languages
Czech (cs)
English (en)
Inventor
Charlotte Moira Norfor Allerton
Christopher Gordon Barber
Keith Michael Devries
Laurence James Harris
Philip Charles Levett
Graham MAW
Joanna Teresa Negri
David James Rawson
Albert Shaw Wood
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0018660A external-priority patent/GB0018660D0/en
Priority claimed from GB0107526A external-priority patent/GB0107526D0/en
Priority claimed from GB0110251A external-priority patent/GB0110251D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of CZ20012713A3 publication Critical patent/CZ20012713A3/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CZ20012713A 2000-07-28 2001-07-25 Způsob přípravy pyrazol[4,3-d]pyrimidin-7-onových sloučenin a jejich meziprodukty CZ20012713A3 (cs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0018660A GB0018660D0 (en) 2000-07-28 2000-07-28 Pharmaceutically active compounds
GB0107526A GB0107526D0 (en) 2001-03-26 2001-03-26 Process for the preparation of pyrazolo [4,3-d] pyrimidin-7-one compounds and intermediates thereof
GB0110251A GB0110251D0 (en) 2001-04-26 2001-04-26 Process for the preparation of pyrazolo[4,4-d]Pyrimidin-7-one compounds and intermediates thereof

Publications (1)

Publication Number Publication Date
CZ20012713A3 true CZ20012713A3 (cs) 2002-04-17

Family

ID=27255823

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20012713A CZ20012713A3 (cs) 2000-07-28 2001-07-25 Způsob přípravy pyrazol[4,3-d]pyrimidin-7-onových sloučenin a jejich meziprodukty

Country Status (17)

Country Link
EP (1) EP1176147A1 (cg-RX-API-DMAC7.html)
JP (1) JP2002105076A (cg-RX-API-DMAC7.html)
KR (1) KR20020010102A (cg-RX-API-DMAC7.html)
CN (1) CN1335317A (cg-RX-API-DMAC7.html)
AR (1) AR035650A1 (cg-RX-API-DMAC7.html)
AU (1) AU754962B2 (cg-RX-API-DMAC7.html)
BR (1) BR0103072A (cg-RX-API-DMAC7.html)
CA (1) CA2354175A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20012713A3 (cg-RX-API-DMAC7.html)
HK (1) HK1040715A1 (cg-RX-API-DMAC7.html)
HU (1) HUP0103075A3 (cg-RX-API-DMAC7.html)
IL (1) IL144516A0 (cg-RX-API-DMAC7.html)
IN (1) IN191315B (cg-RX-API-DMAC7.html)
MX (1) MXPA01007676A (cg-RX-API-DMAC7.html)
PL (1) PL348935A1 (cg-RX-API-DMAC7.html)
RU (1) RU2224759C2 (cg-RX-API-DMAC7.html)
YU (1) YU51701A (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0106631D0 (en) * 2001-03-16 2001-05-09 Pfizer Ltd Pharmaceutically active compounds
US6831074B2 (en) 2001-03-16 2004-12-14 Pfizer Inc Pharmaceutically active compounds
KR100824193B1 (ko) 2003-04-29 2008-04-21 화이자 인코포레이티드 고혈압 치료에 유용한5,7-디아미노피라졸로[4,3-ｄ]피리미딘
JP2006219373A (ja) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
BRPI0509731A (pt) 2004-04-07 2007-09-25 Pfizer pirazol[4,3-d]pirimidinas
JP5254029B2 (ja) * 2005-11-16 2013-08-07 エフ．ホフマン−ラ ロシュ アーゲー Ｔｈｏｃの新規製造方法
CA2645893A1 (en) * 2006-03-17 2007-09-27 Cipla Limited Synthesis of 4-[1-(4-cyano phenyl)-(1,2,4-tr1azol-1-yl)methyl] benzonitrile and 4-[1-(1h-1,2,4-triazol-1-yl)methylene benzonitrile intermediate
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
KR20100033419A (ko) 2007-07-19 2010-03-29 메타볼렉스, 인코포레이티드 당뇨병 및 대사 장애의 치료를 위한 ｒｕｐ3 또는 ｇｐｒ119 수용체의 작용제로서 ｎ-아자시클릭 치환된 피롤, 피라졸, 이미다졸, 트리아졸 및 테트라졸 유도체
CN102666553B (zh) 2009-10-01 2015-05-06 赛马拜制药公司 取代的四唑-1-基-苯氧基甲基-噻唑-2-基-哌啶基-嘧啶盐
ES2676209T3 (es) 2010-06-23 2018-07-17 Metabolex Inc. Composiciones de 5-etil-2-{4-[4-(4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina
CN109862896A (zh) 2016-08-03 2019-06-07 西玛贝医药公司 用于治疗炎症性胃肠疾病或胃肠病症的氧亚甲基芳基化合物
CN119677737A (zh) 2022-04-22 2025-03-21 沃泰克斯药物股份有限公司 用于治疗疼痛的杂芳基化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2089971A (en) * 1937-08-17 Condensation products of
GB9013750D0 (en) * 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9114760D0 (en) * 1991-07-09 1991-08-28 Pfizer Ltd Therapeutic agents
GB9612514D0 (en) * 1996-06-14 1996-08-14 Pfizer Ltd Novel process
GB9822238D0 (en) * 1998-10-12 1998-12-09 Pfizer Ltd Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
CZ20021151A3 (cs) * 1999-10-11 2003-03-12 Pfizer Inc. 5-(2-substituovaný-5-heterocyklylsulfonylpyrid-3-yl)-dihydropyrazolo[4,3-d]-pyrimidin-7-ony jako inhibitory fosfodiesterasy

Also Published As

Publication number Publication date
YU51701A (sh) 2003-12-31
MXPA01007676A (es) 2002-10-23
EP1176147A1 (en) 2002-01-30
RU2224759C2 (ru) 2004-02-27
CA2354175A1 (en) 2002-01-28
HK1040715A1 (zh) 2002-06-21
HUP0103075A2 (hu) 2002-07-29
CN1335317A (zh) 2002-02-13
AR035650A1 (es) 2004-06-23
PL348935A1 (en) 2002-02-11
HU0103075D0 (en) 2001-10-28
JP2002105076A (ja) 2002-04-10
KR20020010102A (ko) 2002-02-02
IN191315B (cg-RX-API-DMAC7.html) 2003-11-22
AU754962B2 (en) 2002-11-28
HUP0103075A3 (en) 2003-04-28
AU5767201A (en) 2002-01-31
IL144516A0 (en) 2002-05-23
BR0103072A (pt) 2002-04-09

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