HK1040715A1 - 製備吡唑並[4，3-d]嘧啶-7-酮化合物的方法及其中間體 - Google Patents

製備吡唑並[4，3-d]嘧啶-7-酮化合物的方法及其中間體

Info

Publication number
HK1040715A1
HK1040715A1 HK02102460.5A HK02102460A HK1040715A1 HK 1040715 A1 HK1040715 A1 HK 1040715A1 HK 02102460 A HK02102460 A HK 02102460A HK 1040715 A1 HK1040715 A1 HK 1040715A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolo
pyrimidin
intermediates
compounds
preparation
Prior art date
Application number
HK02102460.5A
Other languages
English (en)
Inventor
C‧M‧N‧艾爾勒頓
C‧G‧巴伯
K‧M‧迪福利斯
L‧J‧哈裡斯
P‧C‧勒維特
J‧T‧奈格裡
D‧J‧勞森
A‧S‧伍德
Original Assignee
輝瑞大藥廠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0018660A external-priority patent/GB0018660D0/en
Priority claimed from GB0107526A external-priority patent/GB0107526D0/en
Priority claimed from GB0110251A external-priority patent/GB0110251D0/en
Application filed by 輝瑞大藥廠 filed Critical 輝瑞大藥廠
Publication of HK1040715A1 publication Critical patent/HK1040715A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK02102460.5A 2000-07-28 2002-04-03 製備吡唑並[4，3-d]嘧啶-7-酮化合物的方法及其中間體 HK1040715A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0018660A GB0018660D0 (en) 2000-07-28 2000-07-28 Pharmaceutically active compounds
GB0107526A GB0107526D0 (en) 2001-03-26 2001-03-26 Process for the preparation of pyrazolo [4,3-d] pyrimidin-7-one compounds and intermediates thereof
GB0110251A GB0110251D0 (en) 2001-04-26 2001-04-26 Process for the preparation of pyrazolo[4,4-d]Pyrimidin-7-one compounds and intermediates thereof

Publications (1)

Publication Number Publication Date
HK1040715A1 true HK1040715A1 (zh) 2002-06-21

Family

ID=27255823

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102460.5A HK1040715A1 (zh) 2000-07-28 2002-04-03 製備吡唑並[4，3-d]嘧啶-7-酮化合物的方法及其中間體

Country Status (17)

Country Link
EP (1) EP1176147A1 (zh)
JP (1) JP2002105076A (zh)
KR (1) KR20020010102A (zh)
CN (1) CN1335317A (zh)
AR (1) AR035650A1 (zh)
AU (1) AU754962B2 (zh)
BR (1) BR0103072A (zh)
CA (1) CA2354175A1 (zh)
CZ (1) CZ20012713A3 (zh)
HK (1) HK1040715A1 (zh)
HU (1) HUP0103075A3 (zh)
IL (1) IL144516A0 (zh)
IN (1) IN191315B (zh)
MX (1) MXPA01007676A (zh)
PL (1) PL348935A1 (zh)
RU (1) RU2224759C2 (zh)
YU (1) YU51701A (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6831074B2 (en) 2001-03-16 2004-12-14 Pfizer Inc Pharmaceutically active compounds
GB0106631D0 (en) * 2001-03-16 2001-05-09 Pfizer Ltd Pharmaceutically active compounds
OA13050A (en) 2003-04-29 2006-11-10 Pfizer Ltd 5,7-diaminopyrazolo [4,3-D] pyrimidines useful in the treatment of hypertension.
JP2006219373A (ja) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
ATE417849T1 (de) 2004-04-07 2009-01-15 Pfizer Pyrazoloä4,3-düpyrimidine
DE602006013688D1 (de) * 2005-11-16 2010-05-27 Hoffmann La Roche Neues verfahren zur herstellung von thoc
JP2009530256A (ja) * 2006-03-17 2009-08-27 シプラ・リミテッド ４−［１−（４−シアノフェニル）−１−（１，２，４−トリアゾール−１−イル）メチル］ベンゾニトリルおよび４−［１−（１ｈ−１，２，４−トリアゾール−１−イル）メチレンベンゾニトリル中間体
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
JP5489997B2 (ja) 2007-07-19 2014-05-14 シマベイ セラピューティクス， インコーポレーテッド 糖尿病および代謝疾患の治療のためのＲＵＰ３またはＧＰＲｌ１９受容体のアゴニストとしてのＮ−アザ環状置換ピロール、ピラゾール、イミダゾール、トリアゾールおよびテトラゾール誘導体
WO2011041154A1 (en) 2009-10-01 2011-04-07 Metabolex, Inc. Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
CA2802541A1 (en) 2010-06-23 2011-12-29 Metabolex, Inc. Compositions of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
WO2018026890A1 (en) 2016-08-03 2018-02-08 Cymabay Therapeutics Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2089971A (en) * 1937-08-17 Condensation products of
GB9612514D0 (en) * 1996-06-14 1996-08-14 Pfizer Ltd Novel process
GB9822238D0 (en) * 1998-10-12 1998-12-09 Pfizer Ltd Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds

Also Published As

Publication number Publication date
AU754962B2 (en) 2002-11-28
IL144516A0 (en) 2002-05-23
CA2354175A1 (en) 2002-01-28
IN191315B (zh) 2003-11-22
HU0103075D0 (en) 2001-10-28
JP2002105076A (ja) 2002-04-10
HUP0103075A2 (hu) 2002-07-29
PL348935A1 (en) 2002-02-11
RU2224759C2 (ru) 2004-02-27
MXPA01007676A (es) 2002-10-23
KR20020010102A (ko) 2002-02-02
HUP0103075A3 (en) 2003-04-28
YU51701A (sh) 2003-12-31
AU5767201A (en) 2002-01-31
AR035650A1 (es) 2004-06-23
CZ20012713A3 (cs) 2002-04-17
EP1176147A1 (en) 2002-01-30
CN1335317A (zh) 2002-02-13
BR0103072A (pt) 2002-04-09

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