BR0103072A - Processo para a preparação de compostos de pirazolo[4,3-d] pirimidin-7-ona e seus intermediários - Google Patents
Processo para a preparação de compostos de pirazolo[4,3-d] pirimidin-7-ona e seus intermediáriosInfo
- Publication number
- BR0103072A BR0103072A BR0103072-8A BR0103072A BR0103072A BR 0103072 A BR0103072 A BR 0103072A BR 0103072 A BR0103072 A BR 0103072A BR 0103072 A BR0103072 A BR 0103072A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- preparation
- pyrazolo
- pyrimidin
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: "PROCESSO PARA A PREPARAçãO DE COMPOSTOS DE PIRAZOLO[4,3-d]PIRIMIDIN-7-ONA E SEUS INTERMEDIáRIOS". Revela-se um processo para a preparação de compostos de fórmula (I) neste documento, o qual inclui fazer-se reagir um composto de fórmula (II), (III), (IV) ou (V) na presença de ^ -^OR^ 3^ e de um sequestrante ao de hidróxido ou, no caso dos compostos de fórmula (IV), fazerem-se reagir na presença de uma base auxiliar e de um sequestrante ao de hidróxido (isto é ^ -^OR^ 3^ é substituído pela base auxiliar), em que X seja um grupo de partida e R^ 1^ a R^ 4^ sejam tal como definidos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0018660A GB0018660D0 (en) | 2000-07-28 | 2000-07-28 | Pharmaceutically active compounds |
| GB0107526A GB0107526D0 (en) | 2001-03-26 | 2001-03-26 | Process for the preparation of pyrazolo [4,3-d] pyrimidin-7-one compounds and intermediates thereof |
| GB0110251A GB0110251D0 (en) | 2001-04-26 | 2001-04-26 | Process for the preparation of pyrazolo[4,4-d]Pyrimidin-7-one compounds and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0103072A true BR0103072A (pt) | 2002-04-09 |
Family
ID=27255823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0103072-8A BR0103072A (pt) | 2000-07-28 | 2001-07-30 | Processo para a preparação de compostos de pirazolo[4,3-d] pirimidin-7-ona e seus intermediários |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1176147A1 (pt) |
| JP (1) | JP2002105076A (pt) |
| KR (1) | KR20020010102A (pt) |
| CN (1) | CN1335317A (pt) |
| AR (1) | AR035650A1 (pt) |
| AU (1) | AU754962B2 (pt) |
| BR (1) | BR0103072A (pt) |
| CA (1) | CA2354175A1 (pt) |
| CZ (1) | CZ20012713A3 (pt) |
| HK (1) | HK1040715A1 (pt) |
| HU (1) | HUP0103075A3 (pt) |
| IL (1) | IL144516A0 (pt) |
| IN (1) | IN191315B (pt) |
| MX (1) | MXPA01007676A (pt) |
| PL (1) | PL348935A1 (pt) |
| RU (1) | RU2224759C2 (pt) |
| YU (1) | YU51701A (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6831074B2 (en) | 2001-03-16 | 2004-12-14 | Pfizer Inc | Pharmaceutically active compounds |
| GB0106631D0 (en) * | 2001-03-16 | 2001-05-09 | Pfizer Ltd | Pharmaceutically active compounds |
| AU2004234158B2 (en) | 2003-04-29 | 2010-01-28 | Pfizer Inc. | 5,7-diaminopyrazolo[4,3-D]pyrimidines useful in the treatment of hypertension |
| JP2006219373A (ja) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体 |
| US7572799B2 (en) | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
| CA2562251C (en) | 2004-04-07 | 2009-04-28 | Pfizer Inc. | Pyrazolo'4,3-d pyrimidines |
| CA2629077C (en) * | 2005-11-16 | 2014-03-18 | F. Hoffmann-La Roche Ag | Novel process for the preparation of thoc |
| TR200806911T1 (tr) * | 2006-03-17 | 2009-01-21 | Cipla Limited | 4-[1-(4-siyano fenil)-1-(1,2,4-triazol-1-il)metil] benzonitril ile 4[1-(1h-1,2,4-triazol-1-il)metilen benzonitril ara maddesinin sentezi. |
| US7638541B2 (en) | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
| EP2185544B1 (en) | 2007-07-19 | 2014-11-26 | Cymabay Therapeutics, Inc. | N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the rup3 or gpr119 for the treatment of diabetes and metabolic disorders |
| US8410127B2 (en) | 2009-10-01 | 2013-04-02 | Metabolex, Inc. | Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts |
| CN103037843A (zh) | 2010-06-23 | 2013-04-10 | 麦它波莱克斯股份有限公司 | 5-乙基-2-{4-[4-(4-四唑-1-基-苯氧甲基)-噻唑-2-基]-哌啶-1-基}-嘧啶的组合物 |
| KR20190035752A (ko) | 2016-08-03 | 2019-04-03 | 사이머베이 쎄라퓨틱스, 인코퍼레이티드 | 염증성 위장 질환 또는 위장 상태를 치료하기 위한 옥시메틸렌 아릴 화합물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2089971A (en) * | 1937-08-17 | Condensation products of | ||
| GB9612514D0 (en) * | 1996-06-14 | 1996-08-14 | Pfizer Ltd | Novel process |
| GB9822238D0 (en) * | 1998-10-12 | 1998-12-09 | Pfizer Ltd | Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof |
| GB9823101D0 (en) * | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
-
2001
- 2001-07-17 EP EP01306123A patent/EP1176147A1/en not_active Withdrawn
- 2001-07-17 YU YU51701A patent/YU51701A/sh unknown
- 2001-07-20 IN IN698MU2001 patent/IN191315B/en unknown
- 2001-07-23 IL IL14451601A patent/IL144516A0/xx unknown
- 2001-07-25 CZ CZ20012713A patent/CZ20012713A3/cs unknown
- 2001-07-26 CA CA002354175A patent/CA2354175A1/en not_active Abandoned
- 2001-07-26 AU AU57672/01A patent/AU754962B2/en not_active Ceased
- 2001-07-26 AR ARP010103577A patent/AR035650A1/es not_active Application Discontinuation
- 2001-07-26 PL PL01348935A patent/PL348935A1/xx not_active Application Discontinuation
- 2001-07-27 KR KR1020010045414A patent/KR20020010102A/ko not_active Application Discontinuation
- 2001-07-27 RU RU2001121162/04A patent/RU2224759C2/ru not_active IP Right Cessation
- 2001-07-27 HU HU0103075A patent/HUP0103075A3/hu unknown
- 2001-07-27 MX MXPA01007676A patent/MXPA01007676A/es unknown
- 2001-07-27 CN CN01124351A patent/CN1335317A/zh active Pending
- 2001-07-30 BR BR0103072-8A patent/BR0103072A/pt not_active IP Right Cessation
- 2001-07-30 JP JP2001229348A patent/JP2002105076A/ja active Pending
-
2002
- 2002-04-03 HK HK02102460.5A patent/HK1040715A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU0103075D0 (en) | 2001-10-28 |
| RU2224759C2 (ru) | 2004-02-27 |
| AU5767201A (en) | 2002-01-31 |
| HUP0103075A2 (hu) | 2002-07-29 |
| AR035650A1 (es) | 2004-06-23 |
| CZ20012713A3 (cs) | 2002-04-17 |
| IN191315B (pt) | 2003-11-22 |
| KR20020010102A (ko) | 2002-02-02 |
| JP2002105076A (ja) | 2002-04-10 |
| MXPA01007676A (es) | 2002-10-23 |
| AU754962B2 (en) | 2002-11-28 |
| HUP0103075A3 (en) | 2003-04-28 |
| PL348935A1 (en) | 2002-02-11 |
| CA2354175A1 (en) | 2002-01-28 |
| CN1335317A (zh) | 2002-02-13 |
| HK1040715A1 (zh) | 2002-06-21 |
| EP1176147A1 (en) | 2002-01-30 |
| IL144516A0 (en) | 2002-05-23 |
| YU51701A (sh) | 2003-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008. |