CY1703A - Substituted a-amino acids their preparation and pharmaceutical compositions containing them - Google Patents

Substituted a-amino acids their preparation and pharmaceutical compositions containing them

Info

Publication number
CY1703A
CY1703A CY170394A CY170394A CY1703A CY 1703 A CY1703 A CY 1703A CY 170394 A CY170394 A CY 170394A CY 170394 A CY170394 A CY 170394A CY 1703 A CY1703 A CY 1703A
Authority
CY
Cyprus
Prior art keywords
substituted
preparation
amino acids
pharmaceutical compositions
compositions containing
Prior art date
Application number
CY170394A
Other languages
English (en)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of CY1703A publication Critical patent/CY1703A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882Arylalkanephosphonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CY170394A 1986-10-30 1994-01-14 Substituted a-amino acids their preparation and pharmaceutical compositions containing them CY1703A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868625941A GB8625941D0 (en) 1986-10-30 1986-10-30 Substituted alpha-amino acids

Publications (1)

Publication Number Publication Date
CY1703A true CY1703A (en) 1994-01-14

Family

ID=10606531

Family Applications (1)

Application Number Title Priority Date Filing Date
CY170394A CY1703A (en) 1986-10-30 1994-01-14 Substituted a-amino acids their preparation and pharmaceutical compositions containing them

Country Status (27)

Country Link
US (1) US5162311A (pt)
JP (2) JPH0641475B2 (pt)
KR (1) KR950004960B1 (pt)
AT (1) AT393384B (pt)
AU (1) AU614726B2 (pt)
BE (1) BE1002421A4 (pt)
CA (1) CA1310331C (pt)
CH (1) CH677794A5 (pt)
CY (1) CY1703A (pt)
DE (1) DE3736016C2 (pt)
DK (1) DK565987A (pt)
ES (1) ES2012521A6 (pt)
FI (1) FI87222C (pt)
FR (1) FR2606018B1 (pt)
GB (2) GB8625941D0 (pt)
GR (1) GR871659B (pt)
HK (1) HK110393A (pt)
HU (1) HU200465B (pt)
IE (1) IE59310B1 (pt)
IL (1) IL84302A (pt)
IT (1) IT1212033B (pt)
LU (1) LU87031A1 (pt)
NL (1) NL8702485A (pt)
NZ (1) NZ222333A (pt)
PT (1) PT86018B (pt)
SE (1) SE466311B (pt)
ZA (1) ZA878176B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395827A (en) * 1986-04-09 1995-03-07 Guilford Pharmaceuticals Inc. ω-[2-(phosphonoalkyl)phenyl]-2-aminoalkanoic acids as antagonists of excitatory amino acid receptors
US4918064A (en) * 1987-10-21 1990-04-17 G. D. Searle & Co. Phenyl glycines for use in reducing neurotoxic injury
US5175153A (en) * 1987-11-30 1992-12-29 Warner-Lambert Company Substituted alpha-amino acids having pharmaceutical activity
FR2634763B1 (fr) * 1988-08-01 1991-07-12 Inst Nat Sante Rech Med Amino-acides et peptides presentant un residu tyrosine modifiee, leur preparation et leur application comme medicaments
US5177240A (en) * 1988-10-21 1993-01-05 G. D. Searle & Co. O-phosphono(alkyl)-n-sulfonyl-phenyl-alanine derivatives useful as intermediates for preparation of phosphono-hydroisoquinolines
US4997821A (en) * 1988-10-21 1991-03-05 Cordi Alexis A Phosphono-hydroisoquinoline compounds useful in reducing neurotoxic injury
US5100654A (en) * 1989-04-07 1992-03-31 Yale University Phosphorylated derivatives of l-dopa and compositions and methods for increasing the melanin content in mammalian skin and hair
DE3940410A1 (de) * 1989-12-04 1991-06-06 Schering Ag Neue verwendung von nmda-rezeptor-antagonisten
US5238958A (en) * 1990-02-26 1993-08-24 Warner-Lambert Company Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
US5264607A (en) * 1991-09-30 1993-11-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates
US5475129A (en) * 1991-09-30 1995-12-12 The United States Of America As Represented By The Department Of Health And Human Services Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis
US5200546A (en) * 1991-09-30 1993-04-06 The United States Of America As Represented By The Department Of Health And Human Services Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis
GB9325360D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds
US5489717A (en) * 1994-07-08 1996-02-06 Warner-Lambert Company Glutamate (NMDA) receptor antagonists
GB9423019D0 (en) * 1994-11-15 1995-01-04 Sandoz Ltd Improvements in or relating to organic compounds
US5922697A (en) * 1996-10-02 1999-07-13 Warner-Lambert Company Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins
US6133281A (en) * 1996-10-24 2000-10-17 Harbor-Ucla Research And Education Institute NMDA receptor blockers in the therapy of urogenital disease
ATE265213T1 (de) * 1997-09-04 2004-05-15 Novoneuron Inc Noribogain zur behandlung von schmerzen und drogenabhängigkeit
MY153569A (en) * 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
SE9804064D0 (sv) 1998-11-25 1998-11-25 A & Science Invest Ab Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells
MY140707A (en) * 2002-02-28 2010-01-15 Mitsubishi Tanabe Pharma Corp Process for preparing a phenylalanine derivative and intermediates thereof
DE10328260A1 (de) * 2003-06-23 2005-01-27 Schmidt, K.-G., Dr. med. Flupirtine-Präparat
EP1754483A1 (en) * 2005-08-18 2007-02-21 Merck Sante Use of thienopyridone derivatives as AMPK activators and pharmaceutical compositions containing them
BR112012031107A2 (pt) 2010-06-09 2017-07-25 Queen Mary & Westfield College molécula de ligação específica cultivada contra a proteína anx-a1 humana, linha de células de hibridoma, composição farmacêutica , uso da molécula de ligação específica e método para o tratamento de uma doença mediada por linfócitos t em um indivíduo com necessidade do mesmo
GB201121564D0 (en) * 2011-12-14 2012-01-25 Queen Mary & Westfield College Use of antibody
GB201702091D0 (en) 2017-02-08 2017-03-22 Medannex Ltd Specific binding molecules
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE550634A (pt) * 1955-08-30
BE626546A (pt) * 1961-12-30
DE2459491A1 (de) * 1974-12-17 1976-06-24 Bayer Ag Gegenueber isocyanaten reaktive phosphorhaltige flammschutzmittel
US4657899A (en) * 1986-04-09 1987-04-14 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors
US4761405A (en) * 1987-03-04 1988-08-02 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency
US4918064A (en) * 1987-10-21 1990-04-17 G. D. Searle & Co. Phenyl glycines for use in reducing neurotoxic injury

Also Published As

Publication number Publication date
SE8704204L (sv) 1988-05-01
FR2606018A1 (fr) 1988-05-06
HUT47949A (en) 1989-04-28
IL84302A (en) 1993-06-10
DE3736016C2 (de) 1995-04-20
PT86018B (pt) 1990-07-31
IT1212033B (it) 1989-11-08
FI874761A (fi) 1988-05-01
IL84302A0 (en) 1988-03-31
SE466311B (sv) 1992-01-27
NZ222333A (en) 1990-09-26
AU614726B2 (en) 1991-09-12
HU200465B (en) 1990-06-28
GB8625941D0 (en) 1986-12-03
US5162311A (en) 1992-11-10
BE1002421A4 (fr) 1991-02-05
KR950004960B1 (ko) 1995-05-16
SE8704204D0 (sv) 1987-10-28
ES2012521A6 (es) 1990-04-01
LU87031A1 (fr) 1988-05-03
IE59310B1 (en) 1994-02-09
NL8702485A (nl) 1988-05-16
KR890006661A (ko) 1989-06-15
CA1310331C (en) 1992-11-17
FI87222B (fi) 1992-08-31
DK565987A (da) 1988-05-01
AU8040487A (en) 1988-05-05
DK565987D0 (da) 1987-10-28
DE3736016A1 (de) 1988-05-05
ZA878176B (en) 1989-06-28
ATA285187A (de) 1991-03-15
AT393384B (de) 1991-10-10
PT86018A (en) 1987-11-01
GB2198134A (en) 1988-06-08
FR2606018B1 (fr) 1990-11-16
GB8724186D0 (en) 1987-11-18
GR871659B (en) 1988-03-03
GB2198134B (en) 1990-07-04
IE872908L (en) 1988-04-30
JPH0641475B2 (ja) 1994-06-01
FI874761A0 (fi) 1987-10-29
CH677794A5 (pt) 1991-06-28
JPH03101685A (ja) 1991-04-26
FI87222C (fi) 1992-12-10
HK110393A (en) 1993-10-29
IT8748544A0 (it) 1987-10-28
JPS63122693A (ja) 1988-05-26

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