ATE265213T1 - Noribogain zur behandlung von schmerzen und drogenabhängigkeit - Google Patents
Noribogain zur behandlung von schmerzen und drogenabhängigkeitInfo
- Publication number
- ATE265213T1 ATE265213T1 AT98944698T AT98944698T ATE265213T1 AT E265213 T1 ATE265213 T1 AT E265213T1 AT 98944698 T AT98944698 T AT 98944698T AT 98944698 T AT98944698 T AT 98944698T AT E265213 T1 ATE265213 T1 AT E265213T1
- Authority
- AT
- Austria
- Prior art keywords
- noribogain
- drug dependence
- treat pain
- noribogaine
- pain
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5792197P | 1997-09-04 | 1997-09-04 | |
PCT/US1998/018284 WO1999011250A2 (en) | 1997-09-04 | 1998-09-03 | Noribogaine in the treatment of pain and drug addiction |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE265213T1 true ATE265213T1 (de) | 2004-05-15 |
Family
ID=22013572
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98944698T ATE265213T1 (de) | 1997-09-04 | 1998-09-03 | Noribogain zur behandlung von schmerzen und drogenabhängigkeit |
AT03075683T ATE510542T1 (de) | 1997-09-04 | 1998-09-03 | Noribogain zur behandlung von schmerzen und drogenabhängigkeit |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03075683T ATE510542T1 (de) | 1997-09-04 | 1998-09-03 | Noribogain zur behandlung von schmerzen und drogenabhängigkeit |
Country Status (9)
Country | Link |
---|---|
US (6) | US7754710B2 (de) |
EP (4) | EP2246058A1 (de) |
AT (2) | ATE265213T1 (de) |
AU (1) | AU754088B2 (de) |
CA (1) | CA2302754C (de) |
DE (1) | DE69823520T2 (de) |
ES (3) | ES2395268T3 (de) |
IL (2) | IL134796A0 (de) |
WO (1) | WO1999011250A2 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001052851A1 (en) * | 2000-01-22 | 2001-07-26 | Albert Shulman | Methods for the treatment of substance abuse |
WO2002092059A1 (en) * | 2001-05-11 | 2002-11-21 | Endo Pharmaceuticals, Inc. | Abuse-resistant opioid dosage form |
WO2002092060A1 (en) | 2001-05-11 | 2002-11-21 | Endo Pharmaceuticals, Inc. | Abuse-resistant controlled-release opioid dosage form |
ES2546010T3 (es) | 2002-04-05 | 2015-09-17 | Euro-Celtique S.A. | Preparación farmacéutica que contiene oxicodona y naloxona |
EP1702558A1 (de) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Verfahren und Vorrichtung zur Darmtätigkeitserfassung |
KR20110133602A (ko) | 2009-03-10 | 2011-12-13 | 유로-셀티큐 에스.에이. | 옥시코돈 및 날록손을 포함하는 즉시 방출 제약 조성물 |
US8362007B1 (en) * | 2010-05-11 | 2013-01-29 | Demerx, Inc. | Substituted noribogaine |
US8765737B1 (en) | 2010-05-11 | 2014-07-01 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
US9394294B2 (en) | 2010-05-11 | 2016-07-19 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
US9586954B2 (en) | 2010-06-22 | 2017-03-07 | Demerx, Inc. | N-substituted noribogaine prodrugs |
US8802832B2 (en) | 2010-06-22 | 2014-08-12 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
US8741891B1 (en) | 2010-06-22 | 2014-06-03 | Demerx, Inc. | N-substituted noribogaine prodrugs |
US8637648B1 (en) | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
MX2013000733A (es) | 2010-07-23 | 2013-05-30 | Demerx Inc | Composiciones de noribogaina. |
EP2481740B1 (de) * | 2011-01-26 | 2015-11-04 | DemeRx, Inc. | Verfahren und Zusammensetzungen zur Herstellung von Noribogain aus Voacangin |
US8742096B2 (en) * | 2011-03-28 | 2014-06-03 | Demerx, Inc. | Methods and compositions for preparing noribogaine from voacangine |
US9617274B1 (en) | 2011-08-26 | 2017-04-11 | Demerx, Inc. | Synthetic noribogaine |
BR112014005064A2 (pt) * | 2011-09-15 | 2017-04-04 | Demerx Inc | não solvatos de sal de norigobaína |
EP2788355A4 (de) * | 2011-12-08 | 2015-10-21 | Demerx Inc | Stereoselektive totalsynthese von noribogain |
CA2855990A1 (en) * | 2011-12-09 | 2013-06-13 | Demerx, Inc. | Sulfate esters of noribogaine |
CA2855994A1 (en) | 2011-12-09 | 2013-06-13 | Demerx, Inc. | Phosphate esters of noribogaine |
US9150584B2 (en) | 2012-01-25 | 2015-10-06 | Demerx, Inc. | Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them |
WO2013112673A1 (en) | 2012-01-25 | 2013-08-01 | Demerx, Inc. | Synthetic voacangine |
US8940728B2 (en) | 2012-12-20 | 2015-01-27 | Demerx, Inc. | Substituted noribogaine |
US9783535B2 (en) | 2012-12-20 | 2017-10-10 | Demerx, Inc. | Substituted noribogaine |
US9045481B2 (en) | 2012-12-20 | 2015-06-02 | Demerx, Inc. | Substituted noribogaine |
CA2942638A1 (en) * | 2013-03-15 | 2014-09-18 | Demerx, Inc. | Method for noribogaine treatment of addiction in patients on methadone |
MX2016000810A (es) | 2013-07-23 | 2016-08-05 | Euro Celtique Sa | Combinacion de oxicodona y naloxona para su uso en el tratamiento de dolor en pacientes que sufren de dolor y una enfermedad que resulta la disbiosis intestinal y/o aumento del riesgo de la translocacion bacteriana intestinal. |
WO2015095644A1 (en) | 2013-12-20 | 2015-06-25 | AntiOP, Inc. | Intranasal naloxone compositions and methods of making and using same |
US9345711B2 (en) * | 2014-02-18 | 2016-05-24 | Demerx, Inc. | Methods for acute and long-term treatment of drug addiction |
US9561232B2 (en) | 2014-02-18 | 2017-02-07 | Demerx, Inc. | Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use |
JP2017509612A (ja) * | 2014-02-18 | 2017-04-06 | デメルクス,インコーポレイテッド | 薬物中毒の急性および長期間での治療方法。 |
EP3107546A4 (de) * | 2014-02-18 | 2017-10-25 | DemeRx, Inc. | Therapeutische verfahren mit noribogain und verwandten verbindungen |
US20150246055A1 (en) * | 2014-03-03 | 2015-09-03 | Demerx, Inc. | Methods for acute and long-term treatment of opioid and opioid-like drug addiction |
US20150258111A1 (en) * | 2014-03-13 | 2015-09-17 | Demerx, Inc. | Methods and compositions for reducing tolerance to opioid analgesics using ibogaine and derivatives thereof |
US9591978B2 (en) | 2014-03-13 | 2017-03-14 | Demerx, Inc. | Methods and compositions for pre-screening patients for treatment with noribogaine |
WO2015142346A1 (en) * | 2014-03-20 | 2015-09-24 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
WO2015195673A2 (en) | 2014-06-18 | 2015-12-23 | Demerx, Inc. | Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them |
US9549935B2 (en) | 2014-07-14 | 2017-01-24 | Demerx, Inc. | Methods and compositions for treating migraines using noribogaine |
US9592239B2 (en) | 2014-09-12 | 2017-03-14 | Demerx, Inc. | Methods and compositions for ibogaine treatment of impulse control disorder, anxiety-related disorders, violence and/or anger, or regulating food intake |
EP3223906B1 (de) | 2014-11-26 | 2021-01-06 | DemeRx, Inc. | Verfahren und zusammensetzungen zur potenzierung der wirkung von opioidanalgetika mithilfe von iboga-alkaloiden |
EP3340984A4 (de) * | 2015-05-11 | 2019-06-19 | DemeRx, Inc. | Verfahren zur behandlung von opioidabhängigkeit und entzug mittels noribogain |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
KR20220009954A (ko) | 2019-04-17 | 2022-01-25 | 컴퍼스 패쓰파인더 리미티드 | 신경인지 장애, 만성 통증을 치료하고 염증을 감소시키는 방법 |
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-
1998
- 1998-09-03 CA CA2302754A patent/CA2302754C/en not_active Expired - Fee Related
- 1998-09-03 WO PCT/US1998/018284 patent/WO1999011250A2/en active IP Right Grant
- 1998-09-03 AT AT98944698T patent/ATE265213T1/de active
- 1998-09-03 IL IL13479698A patent/IL134796A0/xx active IP Right Grant
- 1998-09-03 ES ES03075683T patent/ES2395268T3/es not_active Expired - Lifetime
- 1998-09-03 AU AU92174/98A patent/AU754088B2/en not_active Ceased
- 1998-09-03 EP EP10170898A patent/EP2246058A1/de not_active Withdrawn
- 1998-09-03 EP EP98944698A patent/EP1009407B1/de not_active Expired - Lifetime
- 1998-09-03 EP EP03075683A patent/EP1327447B1/de not_active Expired - Lifetime
- 1998-09-03 ES ES98944698T patent/ES2224430T3/es not_active Expired - Lifetime
- 1998-09-03 DE DE69823520T patent/DE69823520T2/de not_active Expired - Lifetime
- 1998-09-03 ES ES10180121T patent/ES2435722T3/es not_active Expired - Lifetime
- 1998-09-03 EP EP10180121.5A patent/EP2338494B1/de not_active Expired - Lifetime
- 1998-09-03 AT AT03075683T patent/ATE510542T1/de active
-
2000
- 2000-02-29 IL IL134796A patent/IL134796A/en not_active IP Right Cessation
-
2007
- 2007-04-06 US US11/784,343 patent/US7754710B2/en not_active Expired - Fee Related
-
2010
- 2010-06-08 US US12/796,241 patent/US20100311722A1/en not_active Abandoned
- 2010-06-08 US US12/796,249 patent/US8178524B2/en not_active Expired - Lifetime
- 2010-06-08 US US12/796,247 patent/US20100311723A1/en not_active Abandoned
- 2010-06-15 US US12/815,908 patent/US20100311725A1/en not_active Abandoned
-
2011
- 2011-12-08 US US13/315,127 patent/US20120083485A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20070185085A1 (en) | 2007-08-09 |
EP2338494A1 (de) | 2011-06-29 |
US20100311722A1 (en) | 2010-12-09 |
IL134796A (en) | 2008-11-26 |
EP2246058A1 (de) | 2010-11-03 |
ES2395268T3 (es) | 2013-02-11 |
EP1327447B1 (de) | 2011-05-25 |
US8178524B2 (en) | 2012-05-15 |
CA2302754A1 (en) | 1999-03-11 |
ES2224430T3 (es) | 2005-03-01 |
US20100311723A1 (en) | 2010-12-09 |
AU754088B2 (en) | 2002-11-07 |
EP1009407B1 (de) | 2004-04-28 |
EP1327447A1 (de) | 2003-07-16 |
US7754710B2 (en) | 2010-07-13 |
DE69823520D1 (de) | 2004-06-03 |
DE69823520T2 (de) | 2005-05-12 |
WO1999011250A2 (en) | 1999-03-11 |
AU9217498A (en) | 1999-03-22 |
IL134796A0 (en) | 2001-04-30 |
EP2338494B1 (de) | 2013-07-10 |
CA2302754C (en) | 2011-11-08 |
US20120083485A1 (en) | 2012-04-05 |
ATE510542T1 (de) | 2011-06-15 |
US20100311724A1 (en) | 2010-12-09 |
EP1009407A2 (de) | 2000-06-21 |
ES2435722T3 (es) | 2013-12-23 |
US20100311725A1 (en) | 2010-12-09 |
WO1999011250A3 (en) | 1999-08-05 |
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