ATE291918T1 - Kombinationstherapie zur behandlung von tumoren - Google Patents
Kombinationstherapie zur behandlung von tumorenInfo
- Publication number
- ATE291918T1 ATE291918T1 AT99921972T AT99921972T ATE291918T1 AT E291918 T1 ATE291918 T1 AT E291918T1 AT 99921972 T AT99921972 T AT 99921972T AT 99921972 T AT99921972 T AT 99921972T AT E291918 T1 ATE291918 T1 AT E291918T1
- Authority
- AT
- Austria
- Prior art keywords
- combination therapy
- tumors
- treatment
- gastrin
- combination
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title abstract 2
- FOQYDURHXZVLFT-UHFFFAOYSA-N 2-phenyl-2-pyridin-2-ylethanethioamide Chemical compound C=1C=CC=NC=1C(C(=S)N)C1=CC=CC=C1 FOQYDURHXZVLFT-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- VVIAGPKUTFNRDU-UHFFFAOYSA-N 6S-folinic acid Natural products C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-UHFFFAOYSA-N 0.000 abstract 1
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 abstract 1
- 102100021022 Gastrin Human genes 0.000 abstract 1
- 108010052343 Gastrins Proteins 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 229960002949 fluorouracil Drugs 0.000 abstract 1
- VVIAGPKUTFNRDU-ABLWVSNPSA-N folinic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-ABLWVSNPSA-N 0.000 abstract 1
- 235000008191 folinic acid Nutrition 0.000 abstract 1
- 239000011672 folinic acid Substances 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229960001691 leucovorin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2207—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8568798P | 1998-05-15 | 1998-05-15 | |
| PCT/US1999/010750 WO1999059628A2 (en) | 1998-05-15 | 1999-05-14 | Combination therapy for the treatment of tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE291918T1 true ATE291918T1 (de) | 2005-04-15 |
Family
ID=22193286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99921972T ATE291918T1 (de) | 1998-05-15 | 1999-05-14 | Kombinationstherapie zur behandlung von tumoren |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1076561B1 (de) |
| JP (1) | JP2002515457A (de) |
| KR (1) | KR100699574B1 (de) |
| CN (1) | CN1216605C (de) |
| AT (1) | ATE291918T1 (de) |
| AU (1) | AU745749B2 (de) |
| CA (1) | CA2327439C (de) |
| DE (1) | DE69924483T2 (de) |
| DK (1) | DK1076561T3 (de) |
| ES (1) | ES2237103T3 (de) |
| HU (1) | HUP0101947A3 (de) |
| PL (1) | PL193109B1 (de) |
| PT (1) | PT1076561E (de) |
| WO (1) | WO1999059628A2 (de) |
| ZA (1) | ZA200005962B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2441228A1 (en) * | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
| KR20040049830A (ko) * | 2001-07-09 | 2004-06-12 | 애프톤 코포레이션 | 간, 폐 및 식도의 암 및 전암 상태의 치료 및 예방 |
| EP1528915A2 (de) * | 2002-07-03 | 2005-05-11 | Aphton Corporation | Liposomaler impfstoff |
| CN1781023A (zh) | 2003-03-28 | 2006-05-31 | 埃弗顿有限公司 | 胃泌素激素免疫测定 |
| US20050053664A1 (en) * | 2003-09-08 | 2005-03-10 | Eliezer Zomer | Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer |
| US8674064B2 (en) | 2010-03-03 | 2014-03-18 | Onkologix Ltd | Immunogenic compositions against human progastrin peptides |
| CN101797382B (zh) * | 2010-03-03 | 2013-11-20 | 戚胜美 | 抗人前胃液素多肽免疫组合物 |
| EA201100464A1 (ru) * | 2011-04-06 | 2012-10-30 | Ооо "Метамакс" (Ооо "Метамах") | Фармацевтическая композиция для лечения гиперпролиферативных заболеваний и её применение |
| KR102254957B1 (ko) | 2013-11-22 | 2021-05-25 | 씨엘 바이오사이언시즈 엘엘씨 | 골다공증 치료 및 예방을 위한 가스트린 길항제(ｅｇ ｙｆ476, 네타제피드) |
| JP7469225B2 (ja) | 2017-06-15 | 2024-04-16 | キャンサー アドヴァンシーズ インク． | 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法 |
| US12150978B2 (en) | 2017-06-15 | 2024-11-26 | Cancer Advances Inc. | Compositions and methods for preventing tumors and cancer |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341281C (en) * | 1986-07-09 | 2001-08-07 | Hubert J.P. Schoemaker | Immunotherapy of tumor with monoclonal antibody against the 17-1a antigen |
| EP0380230B1 (de) * | 1989-01-24 | 1994-11-17 | Aphton Corporation | Immunogenische Zusammensetzungen gegen Gastrin-Peptide |
| US5468494A (en) * | 1993-11-12 | 1995-11-21 | Aphton Corp. | Immunogenic compositions against human gastrin 17 |
-
1999
- 1999-05-14 JP JP2000549292A patent/JP2002515457A/ja active Pending
- 1999-05-14 ES ES99921972T patent/ES2237103T3/es not_active Expired - Lifetime
- 1999-05-14 PT PT99921972T patent/PT1076561E/pt unknown
- 1999-05-14 AT AT99921972T patent/ATE291918T1/de not_active IP Right Cessation
- 1999-05-14 CN CN998060119A patent/CN1216605C/zh not_active Expired - Lifetime
- 1999-05-14 WO PCT/US1999/010750 patent/WO1999059628A2/en not_active Ceased
- 1999-05-14 KR KR1020007012783A patent/KR100699574B1/ko not_active Expired - Fee Related
- 1999-05-14 CA CA002327439A patent/CA2327439C/en not_active Expired - Lifetime
- 1999-05-14 PL PL344414A patent/PL193109B1/pl not_active IP Right Cessation
- 1999-05-14 EP EP99921972A patent/EP1076561B1/de not_active Expired - Lifetime
- 1999-05-14 AU AU39045/99A patent/AU745749B2/en not_active Expired
- 1999-05-14 HU HU0101947A patent/HUP0101947A3/hu unknown
- 1999-05-14 DK DK99921972T patent/DK1076561T3/da active
- 1999-05-14 DE DE69924483T patent/DE69924483T2/de not_active Expired - Lifetime
-
2000
- 2000-10-24 ZA ZA200005962A patent/ZA200005962B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69924483T2 (de) | 2006-02-09 |
| CA2327439C (en) | 2005-07-05 |
| PL344414A1 (en) | 2001-11-05 |
| EP1076561A2 (de) | 2001-02-21 |
| ZA200005962B (en) | 2002-01-24 |
| HUP0101947A2 (hu) | 2001-11-28 |
| WO1999059628A3 (en) | 2000-01-13 |
| CN1216605C (zh) | 2005-08-31 |
| DE69924483D1 (de) | 2005-05-04 |
| PL193109B1 (pl) | 2007-01-31 |
| DK1076561T3 (da) | 2005-06-06 |
| CA2327439A1 (en) | 1999-11-25 |
| AU3904599A (en) | 1999-12-06 |
| JP2002515457A (ja) | 2002-05-28 |
| ES2237103T3 (es) | 2005-07-16 |
| PT1076561E (pt) | 2005-08-31 |
| KR20010052355A (ko) | 2001-06-25 |
| EP1076561B1 (de) | 2005-03-30 |
| WO1999059628A2 (en) | 1999-11-25 |
| KR100699574B1 (ko) | 2007-03-23 |
| HUP0101947A3 (en) | 2001-12-28 |
| HK1032360A1 (en) | 2001-07-20 |
| AU745749B2 (en) | 2002-03-28 |
| CN1303288A (zh) | 2001-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1076561 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |