DK85786A - Biologisk aktive fragmenter af human antihaemofilisk faktor og fremgangsmaade til fremstilling deraf - Google Patents
Biologisk aktive fragmenter af human antihaemofilisk faktor og fremgangsmaade til fremstilling deraf Download PDFInfo
- Publication number
- DK85786A DK85786A DK85786A DK85786A DK85786A DK 85786 A DK85786 A DK 85786A DK 85786 A DK85786 A DK 85786A DK 85786 A DK85786 A DK 85786A DK 85786 A DK85786 A DK 85786A
- Authority
- DK
- Denmark
- Prior art keywords
- biologically active
- active fragments
- producing
- antihaemophilic factor
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- E—FIXED CONSTRUCTIONS
- E02—HYDRAULIC ENGINEERING; FOUNDATIONS; SOIL SHIFTING
- E02D—FOUNDATIONS; EXCAVATIONS; EMBANKMENTS; UNDERGROUND OR UNDERWATER STRUCTURES
- E02D31/00—Protective arrangements for foundations or foundation structures; Ground foundation measures for protecting the soil or the subsoil water, e.g. preventing or counteracting oil pollution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/10—Factor VIII, AHF; related peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8501050 | 1985-03-05 | ||
SE8501050A SE8501050D0 (sv) | 1985-03-05 | 1985-03-05 | Biologically active fragments of human antihemophilic factor and method for preparation thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
DK85786D0 DK85786D0 (da) | 1986-02-25 |
DK85786A true DK85786A (da) | 1986-09-06 |
DK164282B DK164282B (da) | 1992-06-01 |
Family
ID=20359353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK085786A DK164282B (da) | 1985-03-05 | 1986-02-25 | Biologisk aktive fragmenter af human antihaemofilisk faktor viii:c, anvendelse af fragmenterne og fremgangsmaade til fremstilling af dem |
Country Status (10)
Country | Link |
---|---|
US (2) | US4749780A (da) |
EP (1) | EP0197901B1 (da) |
JP (1) | JPS61205219A (da) |
AT (1) | ATE65505T1 (da) |
CA (1) | CA1341497C (da) |
DE (1) | DE3680368D1 (da) |
DK (1) | DK164282B (da) |
HK (1) | HK15293A (da) |
SE (1) | SE8501050D0 (da) |
SG (1) | SG1893G (da) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5362854A (en) * | 1983-03-31 | 1994-11-08 | Scripps Clinic & Research Foundation | Factor VIII coagulant polypeptides: method of making |
US7138505B1 (en) | 1984-01-12 | 2006-11-21 | Novartis Vaccines And Diagnostics, Inc. | Factor VIII:C nucleic acid molecules |
SE8501050D0 (sv) * | 1985-03-05 | 1985-03-05 | Kabivitrum Ab | Biologically active fragments of human antihemophilic factor and method for preparation thereof |
KR910006424B1 (ko) * | 1985-08-21 | 1991-08-24 | 인코텍스 비.브이 | 편성브리프(brief) 제조방법 |
US5198349A (en) * | 1986-01-03 | 1993-03-30 | Genetics Institute, Inc. | Method for producing factor VIII:C and analogs |
FI98829C (fi) * | 1986-01-27 | 1997-08-25 | Chiron Corp | Menetelmä rekombinoidun proteiinikompleksin valmistamiseksi, jolla on humaanitekijä VIII:C-aktiivisuutta |
US5422260A (en) * | 1986-05-29 | 1995-06-06 | Genetics Institute, Inc. -Legal Affairs | Human factor VIII:c muteins |
EP0251843A1 (fr) * | 1986-06-06 | 1988-01-07 | Transgene S.A. | Procédé de préparation de facteur VIII à partir de cellules de mammifères |
FR2613379B2 (fr) * | 1987-04-03 | 1990-04-06 | Transgene Sa | Procede de preparation de fragments du facteur viii a partir de cellules de mammiferes |
DE3788944T2 (de) * | 1986-06-24 | 1994-05-26 | Novo Nordisk As | Verfahren zur herstellung eines koagulationsaktiven komplexes vom faktor viii-fragment. |
US4980456A (en) * | 1987-04-06 | 1990-12-25 | Scripps Clinic And Research Foundation | Recombinant factor VIIIC derived fragments |
US6346513B1 (en) | 1987-06-12 | 2002-02-12 | Baxter Trading Gmbh | Proteins with factor VIII activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them |
IL86693A (en) | 1987-06-12 | 1994-06-24 | Stichting Centraal Lab | Proteins that have the activity IIIV of the blood, a process for their preparation that uses cells are produced through genetic engineering and pharmaceutical preparations that contain them |
EP0725708B1 (en) * | 1992-04-06 | 1998-07-08 | Pressmaster Tool Ab | A crimping tool |
EP1652534A3 (en) * | 1992-10-02 | 2007-05-02 | Genetics Institute, LLC | Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer |
US5576291A (en) * | 1993-09-13 | 1996-11-19 | Baxter International Inc. | Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency |
SE9303601D0 (sv) * | 1993-11-01 | 1993-11-01 | Kabi Pharmacia Ab | Improved cell cultivation method and medium |
US6288030B1 (en) | 1993-12-22 | 2001-09-11 | Amgen Inc. | Stem cell factor formulations and methods |
IL113010A0 (en) * | 1994-03-31 | 1995-10-31 | Pharmacia Ab | Pharmaceutical formulation comprising factor VIII or factor ix with an activity of at least 200 IU/ml and an enhancer for improved subcutaneous intramuscular or intradermal administration |
SE503424C2 (sv) * | 1994-11-14 | 1996-06-10 | Pharmacia Ab | Process för rening av rekombinant koagulationsfaktor VIII |
SE9403915D0 (sv) * | 1994-11-14 | 1994-11-14 | Annelie Almstedt | Process A |
SE9501189D0 (sv) * | 1995-03-31 | 1995-03-31 | Pharmacia Ab | Protein formulation |
SE9503380D0 (sv) * | 1995-09-29 | 1995-09-29 | Pharmacia Ab | Protein derivatives |
AU3202797A (en) | 1996-04-24 | 1997-11-12 | Regents Of The University Of Michigan, The | Inactivation resistant factor viii |
US8183344B2 (en) | 1996-04-24 | 2012-05-22 | University Of Michigan | Inactivation resistant factor VIII |
US5851800A (en) * | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
EP0910581B1 (de) * | 1996-06-24 | 2000-04-05 | Max-Planck-Institut für Physiologische und Klinische Forschung Kerckhoff-Klink GmbH | Verfahren zur affinitätschromatographischen aufreinigung von faktor viii |
US6197526B1 (en) | 1999-01-04 | 2001-03-06 | Dyax Corp. | Polypeptides for binding human factor VIII and fragments of human factor VIII |
US7112438B2 (en) * | 1999-01-04 | 2006-09-26 | Dyax Corp. | Binding molecules for human factor VIII and factor VIII-like proteins |
EP1038959A1 (en) | 1999-03-17 | 2000-09-27 | Aventis Behring Gesellschaft mit beschränkter Haftung | Factor VIII without B-domain, comprising one or more insertions of a truncated intron I of factor IX |
SE9901379D0 (sv) | 1999-04-19 | 1999-04-19 | Pharmacia & Upjohn Ab | Receptor structures |
EP1233064A1 (en) | 2001-02-09 | 2002-08-21 | Aventis Behring Gesellschaft mit beschränkter Haftung | Modified factor VIII cDNA and its use for the production of factor VIII |
ES2331909T3 (es) * | 2001-06-14 | 2010-01-20 | The Scripps Research Institute | Factor viii estabilizado con enlaces disulfuro modificados geneticamente. |
US7220718B2 (en) | 2001-08-03 | 2007-05-22 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Oral treatment of hemophilia |
SG10201503304RA (en) * | 2007-12-27 | 2015-06-29 | Baxter Int | Cell culture processes |
EP2704688B1 (en) * | 2011-05-05 | 2019-07-10 | Matinas BioPharma Nanotechnologies, Inc. | Cochleate compositions and methods of making and using same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4361509A (en) * | 1981-12-14 | 1982-11-30 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
US4495175A (en) * | 1982-08-05 | 1985-01-22 | University Of Rochester | Preparation of highly purified human antihemophilic factor |
ZA842418B (en) * | 1983-03-31 | 1984-11-28 | Scripps Clinic Res | Factor viii coagulant polypeptides and monoclonal antibodies to them |
DE3481109D1 (de) * | 1983-05-09 | 1990-03-01 | Novo Nordisk As | Antihaemophilie-faktor-viii-konzentrat und dessen herstellungsverfahren. |
DE10399009I1 (de) * | 1984-01-12 | 2003-10-23 | Chiron Corp | F}r Faktor-VIIIc kodierende DNA-Sequenzen und verwandte DNA-Konstruktionen |
US4710381A (en) * | 1984-05-22 | 1987-12-01 | The Blood Center Of Southeastern Wisconsin | Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing |
US4543210A (en) * | 1984-10-04 | 1985-09-24 | Miles Laboratories, Inc. | Process for producing a high purity antihemophilic factor concentrate |
SE8501050D0 (sv) * | 1985-03-05 | 1985-03-05 | Kabivitrum Ab | Biologically active fragments of human antihemophilic factor and method for preparation thereof |
-
1985
- 1985-03-05 SE SE8501050A patent/SE8501050D0/xx unknown
-
1986
- 1986-02-24 AT AT86850067T patent/ATE65505T1/de not_active IP Right Cessation
- 1986-02-24 DE DE8686850067T patent/DE3680368D1/de not_active Revoked
- 1986-02-24 EP EP86850067A patent/EP0197901B1/en not_active Revoked
- 1986-02-25 DK DK085786A patent/DK164282B/da unknown
- 1986-03-04 JP JP61045506A patent/JPS61205219A/ja active Granted
- 1986-03-04 CA CA000503239A patent/CA1341497C/en not_active Expired - Lifetime
- 1986-03-04 US US06/835,914 patent/US4749780A/en not_active Expired - Lifetime
-
1988
- 1988-04-25 US US07/185,629 patent/US4877614A/en not_active Expired - Lifetime
-
1993
- 1993-01-05 SG SG18/93A patent/SG1893G/en unknown
- 1993-02-25 HK HK152/93A patent/HK15293A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4749780A (en) | 1988-06-07 |
DK85786D0 (da) | 1986-02-25 |
US4877614A (en) | 1989-10-31 |
JPS61205219A (ja) | 1986-09-11 |
EP0197901B1 (en) | 1991-07-24 |
CA1341497C (en) | 2006-02-14 |
ATE65505T1 (de) | 1991-08-15 |
SG1893G (en) | 1993-06-11 |
HK15293A (en) | 1993-03-05 |
EP0197901A1 (en) | 1986-10-15 |
DE3680368D1 (de) | 1991-08-29 |
JPH0547524B2 (da) | 1993-07-19 |
DK164282B (da) | 1992-06-01 |
SE8501050D0 (sv) | 1985-03-05 |
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