CY1218A - Pyridopyrimidines - Google Patents

Pyridopyrimidines

Info

Publication number
CY1218A
CY1218A CY1218A CY121878A CY1218A CY 1218 A CY1218 A CY 1218A CY 1218 A CY1218 A CY 1218A CY 121878 A CY121878 A CY 121878A CY 1218 A CY1218 A CY 1218A
Authority
CY
Cyprus
Prior art keywords
pyridopyrimidines
Prior art date
Application number
CY1218A
Other languages
English (en)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CY1218A publication Critical patent/CY1218A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CY1218A 1977-05-25 1978-05-24 Pyridopyrimidines CY1218A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/800,264 US4122274A (en) 1977-05-25 1977-05-25 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones

Publications (1)

Publication Number Publication Date
CY1218A true CY1218A (en) 1984-04-06

Family

ID=25177928

Family Applications (1)

Application Number Title Priority Date Filing Date
CY1218A CY1218A (en) 1977-05-25 1978-05-24 Pyridopyrimidines

Country Status (26)

Country Link
US (1) US4122274A (fr)
JP (1) JPS6050197B2 (fr)
AT (1) AT365187B (fr)
AU (1) AU521211B2 (fr)
BE (1) BE867295A (fr)
CA (1) CA1098520A (fr)
CH (1) CH642656A5 (fr)
CY (1) CY1218A (fr)
DE (1) DE2822544A1 (fr)
DK (1) DK160279C (fr)
FI (1) FI64594C (fr)
FR (1) FR2401159A1 (fr)
GB (1) GB1596476A (fr)
GR (1) GR71887B (fr)
HK (1) HK25884A (fr)
IE (1) IE46849B1 (fr)
IT (1) IT1105040B (fr)
KE (1) KE3357A (fr)
LU (1) LU79694A1 (fr)
MY (1) MY8500305A (fr)
NL (1) NL190702C (fr)
NO (1) NO150361C (fr)
SE (1) SE437830B (fr)
SG (1) SG73383G (fr)
YU (2) YU42163B (fr)
ZA (1) ZA782816B (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495189A (en) * 1975-11-27 1985-01-22 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. Condensed pyrimidines
HU173438B (hu) * 1975-11-27 1979-05-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
HU180439B (en) * 1977-12-29 1983-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-amino-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones
US4491587A (en) * 1978-05-05 1985-01-01 Mead Johnson & Company Tetrazole derivatives
US4282360A (en) * 1979-10-12 1981-08-04 Hoffmann-La Roche Inc. 7-Methylthio or methylsulfinyl-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid
US4419357A (en) * 1982-01-18 1983-12-06 The Dow Chemical Company 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones
US4507477A (en) * 1982-09-09 1985-03-26 Riker Laboratories, Inc. Process for tetrazolyl-pyrimidinone derivatives
US4476130A (en) * 1982-09-09 1984-10-09 Riker Laboratories, Inc. 3-(1H-Tetrazol-5-yl)-4H-pyrimido[2,1-b]benzoxazol-4-one compounds exhibiting anti-allergic activity
US4474953A (en) * 1982-09-09 1984-10-02 Riker Laboratories, Inc. Process and intermediates for the preparation of 3(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-ones
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents
DK169580B1 (da) * 1985-09-25 1994-12-12 Shionogi & Co 9-(substitueret thio)-4H-pyrido[1,2-a]pyrimidin-4-on-derivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende sådanne derivater
JPS63183581A (ja) * 1985-10-03 1988-07-28 Tokyo Tanabe Co Ltd ピリド〔１，２−ａ〕ピリミジン誘導体、その製造法及びそれを有効成分とするアレルギ−疾患治療薬
JPS62242682A (ja) * 1986-04-16 1987-10-23 Tokyo Tanabe Co Ltd 新規なピリド［１，２―ａ］ピリミジン誘導体及びその製造法
JP2504788B2 (ja) * 1987-11-10 1996-06-05 東京田辺製薬株式会社 ９−メチル−３−（１Ｈ−テトラゾ―ル−５−イル）−４Ｈ−ピリド［１，２−ａ］ピリミジン−４−オンカリウム塩の水性製剤
EP0348527B1 (fr) * 1987-12-25 1993-06-23 Santen Pharmaceutical Co., Ltd. Collyre antiallergique
CA2010336C (fr) * 1989-02-27 1996-11-19 Atsunori Sano Procede de production d'un derive de pyrido [1,2-a] pyrimidine
HU209793B (en) * 1990-09-25 1994-11-28 Chinoin Gyogyszer Es Vegyeszet Process for the production of pyrido[1,2-a]pyrimidine-derivatives and pharmaceutical compositions containing the same
WO1994003172A1 (fr) 1992-07-30 1994-02-17 Tokyo Tanabe Company Limited Remede destine aux troubles inflammatoires de l'intestin
US5527802A (en) * 1992-10-01 1996-06-18 Bristol-Myers Squibb Company New uses of 3-tetrazolo -5,6,7,8- substituted-pyrido (1,2-a) pyrimidin-4-ones
JPH0892093A (ja) * 1994-11-10 1996-04-09 Tokyo Tanabe Co Ltd ９−メチル−３−（１Ｈ−テトラゾール−５−イル）−４Ｈ−ピリド［１，２−ａ］ピリミジン−４−オンの水性製剤
JP4171303B2 (ja) * 2001-02-26 2008-10-22 田辺三菱製薬株式会社 腎疾患・腎不全の予防剤及び／又は治療剤
ITMI20011764A1 (it) * 2001-08-10 2003-02-10 Dinamite Dipharma Spa Metodo per l'ottenimento del pemirolast ad elevata purezza
GB0316546D0 (en) 2003-07-15 2003-08-20 Novartis Ag Process for the manufacture of organic compounds
BRPI0720358A2 (pt) * 2006-12-18 2013-12-24 Cardoz Ab Produto combinado, kit de partes, uso de um produto combinado e métodos de produzir um kit de partes e de tratar um distúrbio inflamatório.
ATE543501T1 (de) * 2006-12-20 2012-02-15 Cardoz Ab Kombination von pemirolast und ramatroban zur verwendung bei der behandlung von entzündlichen erkrankungen
WO2009007673A2 (fr) * 2007-07-11 2009-01-15 Cardoz Ab Nouvelle combinaison pour une utilisation dans le traitement de troubles inflammatoires
WO2009007679A2 (fr) * 2007-07-11 2009-01-15 Cardoz Ab Nouvelle association pour une utilisation dans le traitement de troubles inflammatoires
WO2009007675A2 (fr) * 2007-07-11 2009-01-15 Cardoz Ab Nouvelle association pour une utilisation dans le traitement de troubles inflammatoires
US20110092463A1 (en) * 2008-04-07 2011-04-21 Johan Raud Combination for use in the treatment of inflammatory disorders
PL2443120T3 (pl) * 2009-06-16 2017-04-28 Rspr Pharma Ab Krystaliczna postać pemirolastu
USD661900S1 (en) 2010-02-22 2012-06-19 Bajer Design & Marketing, Inc. Collapsible structure
EA029542B1 (ru) * 2012-02-10 2018-04-30 ПиТиСи ТЕРАПЬЮТИКС, ИНК. ПРОИЗВОДНЫЕ 4Н-ПИРИДО[1,2-а]ПИРИМИДИН-4-ОНА ДЛЯ ЛЕЧЕНИЯ СПИНАЛЬНОЙ МЫШЕЧНОЙ АТРОФИИ
US9371336B2 (en) 2012-03-01 2016-06-21 Ptc Therapeutics, Inc. Compounds for treating spinal muscular atrophy
BR112014023483B1 (pt) 2012-03-23 2022-05-10 Ptc Therapeutics, Inc Composto e seu uso, composição farmacêutica e seu uso
WO2015105657A1 (fr) 2013-12-19 2015-07-16 Ptc Therapeutics, Inc. Procédés pour moduler la quantité de transcrits d'arn
WO2016063085A1 (fr) 2014-10-23 2016-04-28 Rspr Pharma Ab Utilisation de pemirolast dans le traitement de l'asthme aigu
WO2016102941A1 (fr) 2014-12-22 2016-06-30 Rspr Pharma Ab Nouvelle association pémirolast et montélukast
EP3298017B1 (fr) * 2015-05-20 2019-08-14 H. Hoffnabb-La Roche Ag Composés pour le traitement d'une amyotrophie spinale
US10668171B2 (en) 2015-05-30 2020-06-02 Ptc Therapeutics, Inc. Methods for modulating RNA splicing
GB201518831D0 (en) 2015-10-23 2015-12-09 Rspr Pharma Ab New use
JP2019500352A (ja) 2015-12-10 2019-01-10 ピーティーシー セラピューティクス， インコーポレイテッド ハンチントン病の治療方法
GB201601138D0 (en) * 2016-01-21 2016-03-09 Rspr Pharma Ab New use
WO2018098446A1 (fr) 2016-11-28 2018-05-31 Ptc Therapeutics, Inc Procédés de modulation de l'épissage de l'arn
SG11201911615WA (en) 2017-06-05 2020-01-30 Ptc Therapeutics Inc Compounds for treating huntington's disease
CN111372611A (zh) 2017-06-14 2020-07-03 Ptc医疗公司 修饰rna剪接的方法
WO2019005980A1 (fr) 2017-06-28 2019-01-03 Ptc Therapeutics, Inc. Procédés de traitement de la maladie de huntington
CN111163838B (zh) 2017-06-28 2023-03-28 Ptc医疗公司 用于治疗亨廷顿氏病的方法
CN112135815A (zh) 2018-03-27 2020-12-25 Ptc医疗公司 用于治疗亨廷顿氏病的化合物
EP3814360A1 (fr) 2018-06-27 2021-05-05 PTC Therapeutics, Inc. Composés hétéroaryles pour le traitement de la maladie de huntington
CN112654625B (zh) 2018-06-27 2024-08-06 Ptc医疗公司 用于治疗亨廷顿氏病的杂环和杂芳基化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072485A (en) * 1960-08-24 1963-01-08 Eastman Kodak Co Optically sensitized azido polymers for photomechanical resist compositions
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
US3960847A (en) * 1972-04-17 1976-06-01 E. R. Squibb & Sons, Inc. 9-Substituted-4-oxopyrido(1,2-α)pyrimidine-3-carboxylic acids and derivatives thereof
US3929787A (en) * 1974-04-22 1975-12-30 Squibb & Sons Inc 6,7,8,9-Tetrahydro-pyrido(1,2-a)pyrimidin-4-ones
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
US4017625A (en) * 1975-08-01 1977-04-12 Pfizer Inc. Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones

Also Published As

Publication number Publication date
DE2822544A1 (de) 1978-12-07
IE781036L (en) 1978-11-25
JPS5436294A (en) 1979-03-16
FR2401159A1 (fr) 1979-03-23
HK25884A (en) 1984-03-30
FI781614A (fi) 1978-11-26
IT7849523A0 (it) 1978-05-24
CA1098520A (fr) 1981-03-31
DK228878A (da) 1978-11-26
FI64594B (fi) 1983-08-31
JPS6050197B2 (ja) 1985-11-07
US4122274A (en) 1978-10-24
CH642656A5 (de) 1984-04-30
SE437830B (sv) 1985-03-18
SE7805954L (sv) 1978-11-26
DK160279C (da) 1991-07-22
GB1596476A (en) 1981-08-26
FI64594C (fi) 1983-12-12
KE3357A (en) 1984-02-03
AU3631978A (en) 1979-11-29
DK160279B (da) 1991-02-18
DE2822544C2 (fr) 1988-10-27
NO150361C (no) 1984-10-03
YU123678A (en) 1983-02-28
NL190702B (nl) 1994-02-01
LU79694A1 (fr) 1979-02-02
AU521211B2 (en) 1982-03-25
MY8500305A (en) 1985-12-31
ATA373278A (de) 1981-05-15
BE867295A (fr) 1978-11-20
NL190702C (nl) 1994-07-01
NO781786L (no) 1978-11-28
IT1105040B (it) 1985-10-28
NL7805534A (nl) 1978-11-28
NO150361B (no) 1984-06-25
SG73383G (en) 1984-08-03
AT365187B (de) 1981-12-28
YU42163B (en) 1988-06-30
IE46849B1 (en) 1983-10-05
FR2401159B1 (fr) 1983-05-20
YU233082A (en) 1988-08-31
YU44212B (en) 1990-04-30
ZA782816B (en) 1979-05-30
GR71887B (fr) 1983-08-04

Similar Documents

Publication Publication Date Title
KE3357A (en) Pyridopyrimidines
DE2862306D1 (en) X-ray-apparatus
AU4201478A (en) Step-stools
GB2002639A (en) Playballs
MY8500438A (en) Pyranoquinolinones
NZ187543A (en) 1-acetylenealkylamines
AU3728978A (en) Sulfamoyl-aryl-ketones
AU3526278A (en) L-sucrose
SG82584G (en) 3-indolyl-tertiary butylaminopropanols
AU4022878A (en) Thiopropionamides
HK13681A (en) Pyridobenzodiazepines
JPS543584A (en) Ceilometer
AU3677378A (en) N-acylmethyl-chloroacetanilides
GB2012308A (en) Electroplatingl
CS541878A1 (en) Zpusob vyroby tricyklickych derivatu pyrimidinu
JPS5452099A (en) Dibenzocycloocteneimine
JPS546386A (en) Hemodynamometer
AU4255778A (en) 3-di-n-propyl-acetoxy-benzodiazepin-2-ones
GB2009186A (en) Stailizer
AU3355078A (en) Aryl-hexafuranosides
AU3533578A (en) Micro-mill-mixer
GB2007228B (en) Tertiaryalcohols
JPS5491841A (en) Superrleak
GB2004871A (en) Benzodifuranes
IL55609A0 (en) N-substututed bentothiazolines