IT7849523A0 - 3-1h-tetrazol-5-il-4h-pirido 1,2-a pirimidin-4-oni sostituiti utili in particolare come agenti terapeutici per inibire le reazioni allergiche e procedimento per la produzione dei detti derivati - Google Patents

3-1h-tetrazol-5-il-4h-pirido 1,2-a pirimidin-4-oni sostituiti utili in particolare come agenti terapeutici per inibire le reazioni allergiche e procedimento per la produzione dei detti derivati

Info

Publication number
IT7849523A0
IT7849523A0 IT7849523A IT4952378A IT7849523A0 IT 7849523 A0 IT7849523 A0 IT 7849523A0 IT 7849523 A IT7849523 A IT 7849523A IT 4952378 A IT4952378 A IT 4952378A IT 7849523 A0 IT7849523 A0 IT 7849523A0
Authority
IT
Italy
Prior art keywords
oni
tetrazol
pyrido
pyrimidin
derivatives
Prior art date
Application number
IT7849523A
Other languages
English (en)
Other versions
IT1105040B (it
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT7849523A0 publication Critical patent/IT7849523A0/it
Application granted granted Critical
Publication of IT1105040B publication Critical patent/IT1105040B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
IT49523/78A 1977-05-25 1978-05-24 3-1h-tetrazol-5-il-4h-pirido 1,2-a pirimidin-4-oni sostituiti utili in particolare come agenti terapeutici per inibire le reazioni allergiche e procedimento per la produzione dei detti derivati IT1105040B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/800,264 US4122274A (en) 1977-05-25 1977-05-25 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones

Publications (2)

Publication Number Publication Date
IT7849523A0 true IT7849523A0 (it) 1978-05-24
IT1105040B IT1105040B (it) 1985-10-28

Family

ID=25177928

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49523/78A IT1105040B (it) 1977-05-25 1978-05-24 3-1h-tetrazol-5-il-4h-pirido 1,2-a pirimidin-4-oni sostituiti utili in particolare come agenti terapeutici per inibire le reazioni allergiche e procedimento per la produzione dei detti derivati

Country Status (26)

Country Link
US (1) US4122274A (it)
JP (1) JPS6050197B2 (it)
AT (1) AT365187B (it)
AU (1) AU521211B2 (it)
BE (1) BE867295A (it)
CA (1) CA1098520A (it)
CH (1) CH642656A5 (it)
CY (1) CY1218A (it)
DE (1) DE2822544A1 (it)
DK (1) DK160279C (it)
FI (1) FI64594C (it)
FR (1) FR2401159A1 (it)
GB (1) GB1596476A (it)
GR (1) GR71887B (it)
HK (1) HK25884A (it)
IE (1) IE46849B1 (it)
IT (1) IT1105040B (it)
KE (1) KE3357A (it)
LU (1) LU79694A1 (it)
MY (1) MY8500305A (it)
NL (1) NL190702C (it)
NO (1) NO150361C (it)
SE (1) SE437830B (it)
SG (1) SG73383G (it)
YU (2) YU42163B (it)
ZA (1) ZA782816B (it)

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HU180439B (en) * 1977-12-29 1983-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-amino-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones
US4491587A (en) * 1978-05-05 1985-01-01 Mead Johnson & Company Tetrazole derivatives
US4282360A (en) * 1979-10-12 1981-08-04 Hoffmann-La Roche Inc. 7-Methylthio or methylsulfinyl-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid
US4419357A (en) * 1982-01-18 1983-12-06 The Dow Chemical Company 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones
US4507477A (en) * 1982-09-09 1985-03-26 Riker Laboratories, Inc. Process for tetrazolyl-pyrimidinone derivatives
US4474953A (en) * 1982-09-09 1984-10-02 Riker Laboratories, Inc. Process and intermediates for the preparation of 3(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-ones
US4476130A (en) * 1982-09-09 1984-10-09 Riker Laboratories, Inc. 3-(1H-Tetrazol-5-yl)-4H-pyrimido[2,1-b]benzoxazol-4-one compounds exhibiting anti-allergic activity
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents
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JPS62242682A (ja) * 1986-04-16 1987-10-23 Tokyo Tanabe Co Ltd 新規なピリド［１，２―ａ］ピリミジン誘導体及びその製造法
JP2504788B2 (ja) * 1987-11-10 1996-06-05 東京田辺製薬株式会社 ９−メチル−３−（１Ｈ−テトラゾ―ル−５−イル）−４Ｈ−ピリド［１，２−ａ］ピリミジン−４−オンカリウム塩の水性製剤
US5034230A (en) * 1987-12-25 1991-07-23 Santen Pharmaceutical Co., Ltd. Anti-allergic ophthalmics
CA2010336C (en) * 1989-02-27 1996-11-19 Atsunori Sano Process for producing pyrido[1,2-a]pyrimidine derivative
HU209793B (en) * 1990-09-25 1994-11-28 Chinoin Gyogyszer Es Vegyeszet Process for the production of pyrido[1,2-a]pyrimidine-derivatives and pharmaceutical compositions containing the same
US5525605A (en) 1992-07-30 1996-06-11 Tokyo Tanabe Company Limited Remedy for inflammatory intestinal diseases
US5527802A (en) * 1992-10-01 1996-06-18 Bristol-Myers Squibb Company New uses of 3-tetrazolo -5,6,7,8- substituted-pyrido (1,2-a) pyrimidin-4-ones
JPH0892093A (ja) * 1994-11-10 1996-04-09 Tokyo Tanabe Co Ltd ９−メチル−３−（１Ｈ−テトラゾール−５−イル）−４Ｈ−ピリド［１，２−ａ］ピリミジン−４−オンの水性製剤
KR100885007B1 (ko) * 2001-02-26 2009-02-20 미쓰비시 타나베 파마 코퍼레이션 신질환·신부전의 예방 또는 치료를 위한 약학 조성물
ITMI20011764A1 (it) * 2001-08-10 2003-02-10 Dinamite Dipharma Spa Metodo per l'ottenimento del pemirolast ad elevata purezza
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CA2720547A1 (en) * 2008-04-07 2009-10-15 Cardoz Ab New combination for use in the treatment of inflammatory disorders
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US9914722B2 (en) 2012-03-23 2018-03-13 Ptc Therapeutics, Inc. Compounds for treating spinal muscular atrophy
EP3082820B1 (en) 2013-12-19 2022-07-20 PTC Therapeutics, Inc. Methods for modulating the amount of rna transcripts
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WO2016102941A1 (en) 2014-12-22 2016-06-30 Rspr Pharma Ab New combination of pemirolast and montelukast
WO2016184832A1 (en) * 2015-05-20 2016-11-24 F. Hoffmann-La Roche Ag Compounds for treating spinal muscular atrophy
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Also Published As

Publication number Publication date
BE867295A (fr) 1978-11-20
FI781614A (fi) 1978-11-26
CY1218A (en) 1984-04-06
FI64594B (fi) 1983-08-31
SG73383G (en) 1984-08-03
NL190702C (nl) 1994-07-01
YU44212B (en) 1990-04-30
DK160279C (da) 1991-07-22
MY8500305A (en) 1985-12-31
YU123678A (en) 1983-02-28
NO781786L (no) 1978-11-28
JPS5436294A (en) 1979-03-16
LU79694A1 (fr) 1979-02-02
AU521211B2 (en) 1982-03-25
AT365187B (de) 1981-12-28
FR2401159A1 (fr) 1979-03-23
DE2822544C2 (it) 1988-10-27
NO150361B (no) 1984-06-25
CH642656A5 (de) 1984-04-30
FI64594C (fi) 1983-12-12
YU233082A (en) 1988-08-31
DK160279B (da) 1991-02-18
IE781036L (en) 1978-11-25
NL190702B (nl) 1994-02-01
AU3631978A (en) 1979-11-29
SE7805954L (sv) 1978-11-26
ATA373278A (de) 1981-05-15
ZA782816B (en) 1979-05-30
JPS6050197B2 (ja) 1985-11-07
IE46849B1 (en) 1983-10-05
GR71887B (it) 1983-08-04
NO150361C (no) 1984-10-03
US4122274A (en) 1978-10-24
DE2822544A1 (de) 1978-12-07
CA1098520A (en) 1981-03-31
DK228878A (da) 1978-11-26
HK25884A (en) 1984-03-30
GB1596476A (en) 1981-08-26
SE437830B (sv) 1985-03-18
FR2401159B1 (it) 1983-05-20
IT1105040B (it) 1985-10-28
KE3357A (en) 1984-02-03
NL7805534A (nl) 1978-11-28
YU42163B (en) 1988-06-30

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