CY1124880T1 - Φαρμακευτικες συνθεσεις ατροπινης - Google Patents
Φαρμακευτικες συνθεσεις ατροπινηςInfo
- Publication number
- CY1124880T1 CY1124880T1 CY20211101132T CY211101132T CY1124880T1 CY 1124880 T1 CY1124880 T1 CY 1124880T1 CY 20211101132 T CY20211101132 T CY 20211101132T CY 211101132 T CY211101132 T CY 211101132T CY 1124880 T1 CY1124880 T1 CY 1124880T1
- Authority
- CY
- Cyprus
- Prior art keywords
- atropine
- pharmaceutical compositions
- free
- compositions
- substantially preservative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/08—Mydriatics or cycloplegics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
Abstract
Το εφευρετικό αντικείμενο προσανατολίζεται σε συνθέσεις και μεθόδους για αποστειρωμένες και σταθερές στην αποθήκευση, χαμηλής δόσης μορφοποιήσεις ατροπίνης με βελτιωμένη σταθερότητα. Κατά μέγιστη προτίμηση, οι συνθέσεις που παρουσιάζονται στο παρόν είναι ουσιαστικά χωρίς συντηρητικά και παρουσιάζουν λιγότερο από 0,35% τροπικό οξύ από την αποσύνθεση της ατροπίνης. Πλεονεκτικά, οι μορφοποιήσεις που εξετάζονται είναι επίσης ουσιαστικά χωρίς συντηρητικά.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762505027P | 2017-05-11 | 2017-05-11 | |
PCT/US2018/032017 WO2018209051A1 (en) | 2017-05-11 | 2018-05-10 | Atropine pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1124880T1 true CY1124880T1 (el) | 2022-11-25 |
Family
ID=64096170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20211101132T CY1124880T1 (el) | 2017-05-11 | 2021-12-23 | Φαρμακευτικες συνθεσεις ατροπινης |
Country Status (24)
Country | Link |
---|---|
US (12) | US10251875B2 (el) |
EP (2) | EP3548000B1 (el) |
JP (5) | JP6557379B2 (el) |
KR (1) | KR102281667B1 (el) |
CN (1) | CN110621298B (el) |
AU (1) | AU2018265257B2 (el) |
BR (1) | BR112019023515A2 (el) |
CA (1) | CA3063228C (el) |
CL (1) | CL2019003228A1 (el) |
CO (1) | CO2019012893A2 (el) |
CY (1) | CY1124880T1 (el) |
ES (1) | ES2901140T3 (el) |
HR (1) | HRP20212019T1 (el) |
HU (1) | HUE056595T2 (el) |
LT (1) | LT3548000T (el) |
MX (1) | MX2019013218A (el) |
PH (1) | PH12019502701A1 (el) |
PL (1) | PL3548000T3 (el) |
PT (1) | PT3548000T (el) |
RS (1) | RS62817B1 (el) |
RU (1) | RU2745603C1 (el) |
SG (1) | SG11201910085UA (el) |
SI (1) | SI3548000T1 (el) |
WO (1) | WO2018209051A1 (el) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
US11382909B2 (en) | 2014-09-05 | 2022-07-12 | Sydnexis, Inc. | Ophthalmic composition |
WO2016196367A1 (en) | 2015-05-29 | 2016-12-08 | Sydnexis, Inc. | D2o stabilized pharmaceutical formulations |
UA126195C2 (uk) * | 2016-05-25 | 2022-08-31 | Сінгапур Хелт Сервісіз Пте Лтд | Водна композиція, яка містить атропін |
EP3548000B1 (en) | 2017-05-11 | 2021-11-10 | Vyluma Inc. | Atropine pharmaceutical compositions |
CN115300226A (zh) | 2017-06-10 | 2022-11-08 | 艾诺维亚股份有限公司 | 用于将一体积的流体输送到眼睛的设备 |
US11554115B2 (en) * | 2018-03-14 | 2023-01-17 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative for treatment of triple-negative breast cancer |
JP7378959B2 (ja) * | 2018-05-11 | 2023-11-14 | 千寿製薬株式会社 | 眼科用組成物 |
WO2020219707A1 (en) * | 2019-04-24 | 2020-10-29 | Allergan, Inc. | Compositions and methods for treatment of ocular conditions |
WO2021001806A1 (en) * | 2019-07-04 | 2021-01-07 | Ocular Discovery Ltd. | Stable dipyridamole formulations with reduced impurities |
US20230041788A1 (en) * | 2019-12-16 | 2023-02-09 | Sydnexis, Inc. | Ophthalmic compositions comprising d2o |
CN110917133A (zh) * | 2019-12-23 | 2020-03-27 | 河北科技大学 | 一种治疗近视的滴眼剂及其制备方法 |
CA3181212A1 (en) * | 2020-05-05 | 2021-11-11 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
CN111821259A (zh) * | 2020-07-14 | 2020-10-27 | 艾尔健康眼药(辽宁)有限公司 | 一种眼用药物组合物 |
CN111840221A (zh) * | 2020-08-25 | 2020-10-30 | 安徽博诺美科生物医药有限公司 | 一种硫酸阿托品滴眼液 |
WO2022130033A1 (en) * | 2020-12-17 | 2022-06-23 | Sun Pharmaceutical Industries Limited | An aqueous sterile solution of atropine for ophthalmic use |
WO2022197633A1 (en) * | 2021-03-16 | 2022-09-22 | Vyluma Inc. | Multi-dose container for ophthalmic compositions |
EP4088714A1 (en) | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic pharmaceutical composition comprising atropine |
EP4088713A1 (en) | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic pharmaceutical composition comprising atropine |
CN113440486B (zh) * | 2021-06-02 | 2022-12-20 | 苏州欧康维视生物科技有限公司 | 一种用于预防或治疗眼科疾病的滴眼剂组合物及其制备方法 |
TW202333662A (zh) * | 2021-11-10 | 2023-09-01 | 美商偉視醫療股份有限公司 | 增強抗老花眼效果之卡巴可(carbachol)調配物 |
CN114129511A (zh) * | 2021-12-07 | 2022-03-04 | 河南润弘制药股份有限公司 | 一种具有改进稳定性的硫酸阿托品注射液 |
WO2023152642A1 (en) * | 2022-02-08 | 2023-08-17 | Avaca Pharma Private Limited | Ophthalmic compositions and methods thereof |
US20230277521A1 (en) * | 2022-03-07 | 2023-09-07 | Harrow Ip, Llc | Extended-release pharmaceutical compositions for treating eye conditions |
CN114569551A (zh) * | 2022-03-21 | 2022-06-03 | 杭州赫尔斯科技有限公司 | 阿托品滴眼液及其制备方法 |
WO2023201315A2 (en) * | 2022-04-14 | 2023-10-19 | TearClear Corp. | Ophthalmic agent in preservative removal device |
CN115177584A (zh) * | 2022-07-14 | 2022-10-14 | 成都市海通药业有限公司 | 一种硫酸阿托品注射液的制备方法 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU86521A1 (fr) | 1986-07-18 | 1988-02-02 | Oreal | Procede de teinture des cheveux avec des colorants hydroxyquinoniques et des sels metalliques |
IL85312A (en) | 1988-02-03 | 1991-08-16 | Israel State | Injectable pharmaceutical compositions having improved stability |
JP2617508B2 (ja) * | 1988-02-05 | 1997-06-04 | エーザイ株式会社 | 安定なジフェンヒドラミン含有水溶液 |
US5460834A (en) * | 1991-12-13 | 1995-10-24 | Alcon Laboratories, Inc. | Combinations of polymers for use in physiological tear compositions |
US5716952A (en) * | 1992-03-18 | 1998-02-10 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of muscarinic antagonists |
SE9401108D0 (sv) * | 1994-03-31 | 1994-03-31 | Leiras Oy | Ophthalmic composition I |
US20030129083A1 (en) | 1997-11-26 | 2003-07-10 | Advanced Medical Optics, Inc. | Multi purpose contact lens care compositions including propylene glycol or glycerin |
US6164282A (en) | 1999-01-27 | 2000-12-26 | Allergan Sales, Inc. | Methods for restoring and/or enhancing accommodation in pseudo phakia |
WO2002005822A2 (en) * | 2000-07-14 | 2002-01-24 | Allergan, Inc. | Compositions containing therapeutically active components having enhanced solubility |
US20020198209A1 (en) | 2001-05-03 | 2002-12-26 | Allergan Sales Inc. | Compositions having enhanced pharmacokinetic characteristics |
US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
US7851504B2 (en) | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
CN101049287A (zh) | 2006-04-07 | 2007-10-10 | 财团法人长庚纪念医院 | 抑制近视度数增加的低浓度阿托平眼药剂及其制造方法 |
US20070254914A1 (en) * | 2006-05-01 | 2007-11-01 | Non-Profit Organization Chang Gung Memorial Hospital | Low-concentration atropine solution for preventing myopia progression and preparing method thereof |
JP2007308398A (ja) * | 2006-05-17 | 2007-11-29 | Chang Gung Memorial Hospital | 目薬、及びその製造方法 |
CA2702082A1 (en) * | 2007-10-08 | 2009-04-16 | Fovea Pharmaceuticals Sa | Aqueous ophthalmic formulations |
US8883214B2 (en) | 2009-01-13 | 2014-11-11 | The Regents Of The University Of California | Implantable delivery vehicle for ocular delivery of muscarinic antagonists |
US20120203161A1 (en) | 2009-08-12 | 2012-08-09 | Seros Medical, Llc | Deuterated water and riboflavin solution for extending singlet oxygen lifetimes in treatment of ocular tissue and method of use |
WO2012161655A1 (en) | 2011-05-23 | 2012-11-29 | Singapore Health Services Pte Ltd | Composition and/or method for reducing and/or preventing myopia progression comprising atropine |
JP5753957B2 (ja) * | 2013-01-31 | 2015-07-22 | 千寿製薬株式会社 | 安定な水性液剤 |
SG11201508453YA (en) | 2013-05-06 | 2015-11-27 | Kaohsiung Chang Gung Memorial Hospital | Pharmaceutical composition and uses thereof |
EP3973954A1 (en) * | 2013-10-15 | 2022-03-30 | Pharmathen S.A. | Preservative free pharmaceutical compositions for ophthalmic administration |
US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
US20160009705A1 (en) | 2014-06-24 | 2016-01-14 | Sydnexis, Inc. | Ophthalmic composition |
WO2016013993A1 (en) | 2014-07-25 | 2016-01-28 | Imuneks Farma Llac Sanayi Ve Ticaret A.Ş. | Stable preservative free ophthalmic formulations of opioid antagonists |
US10010502B2 (en) | 2015-05-19 | 2018-07-03 | Amorphex Therapeutics Llc | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation |
MX2017016517A (es) | 2015-06-18 | 2018-05-28 | Presbyopia Therapies Llc | Composiciones estables al almacenamiento y metodos para el tratamiento de errores de refraccion del ojo. |
UA126195C2 (uk) | 2016-05-25 | 2022-08-31 | Сінгапур Хелт Сервісіз Пте Лтд | Водна композиція, яка містить атропін |
EP3548000B1 (en) * | 2017-05-11 | 2021-11-10 | Vyluma Inc. | Atropine pharmaceutical compositions |
US11191751B1 (en) | 2020-10-08 | 2021-12-07 | Ads Therapeutics Llc | Topical ophthalmological atropine free base compositions |
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2018
- 2018-05-10 EP EP18798073.5A patent/EP3548000B1/en active Active
- 2018-05-10 SG SG11201910085U patent/SG11201910085UA/en unknown
- 2018-05-10 RS RS20211580A patent/RS62817B1/sr unknown
- 2018-05-10 RU RU2019139290A patent/RU2745603C1/ru active
- 2018-05-10 KR KR1020197036249A patent/KR102281667B1/ko active IP Right Review Request
- 2018-05-10 PT PT187980735T patent/PT3548000T/pt unknown
- 2018-05-10 AU AU2018265257A patent/AU2018265257B2/en active Active
- 2018-05-10 ES ES18798073T patent/ES2901140T3/es active Active
- 2018-05-10 PL PL18798073T patent/PL3548000T3/pl unknown
- 2018-05-10 BR BR112019023515A patent/BR112019023515A2/pt active Search and Examination
- 2018-05-10 US US15/976,279 patent/US10251875B2/en active Active
- 2018-05-10 WO PCT/US2018/032017 patent/WO2018209051A1/en unknown
- 2018-05-10 HR HRP20212019TT patent/HRP20212019T1/hr unknown
- 2018-05-10 HU HUE18798073A patent/HUE056595T2/hu unknown
- 2018-05-10 EP EP21205568.5A patent/EP3970694A1/en active Pending
- 2018-05-10 LT LTEPPCT/US2018/032017T patent/LT3548000T/lt unknown
- 2018-05-10 CN CN201880031247.6A patent/CN110621298B/zh active Active
- 2018-05-10 JP JP2018091739A patent/JP6557379B2/ja active Active
- 2018-05-10 SI SI201830521T patent/SI3548000T1/sl unknown
- 2018-05-10 MX MX2019013218A patent/MX2019013218A/es unknown
- 2018-05-10 CA CA3063228A patent/CA3063228C/en active Active
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2019
- 2019-02-20 US US16/280,669 patent/US10576074B2/en active Active
- 2019-02-20 US US16/280,585 patent/US10610525B2/en active Active
- 2019-02-20 US US16/280,552 patent/US11071732B2/en active Active
- 2019-02-20 US US16/280,405 patent/US10583132B2/en active Active
- 2019-02-20 US US16/280,384 patent/US10568875B2/en active Active
- 2019-07-11 JP JP2019129403A patent/JP6681502B2/ja active Active
- 2019-07-11 JP JP2019129405A patent/JP6681503B2/ja active Active
- 2019-07-11 JP JP2019129396A patent/JP6865476B2/ja active Active
- 2019-11-11 CL CL2019003228A patent/CL2019003228A1/es unknown
- 2019-11-18 CO CONC2019/0012893A patent/CO2019012893A2/es unknown
- 2019-11-28 PH PH12019502701A patent/PH12019502701A1/en unknown
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2020
- 2020-07-20 US US16/933,642 patent/US11464769B2/en active Active
- 2020-08-31 US US17/007,816 patent/US11730727B2/en active Active
- 2020-08-31 US US17/007,900 patent/US11730728B2/en active Active
- 2020-09-09 US US17/016,186 patent/US11707458B2/en active Active
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2021
- 2021-01-11 US US17/145,589 patent/US11642338B2/en active Active
- 2021-03-30 JP JP2021056894A patent/JP7332179B2/ja active Active
- 2021-12-23 CY CY20211101132T patent/CY1124880T1/el unknown
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2023
- 2023-06-28 US US18/343,636 patent/US20230355604A1/en active Pending
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