CL2019003228A1 - Composiciones farmacéuticas de atropina. - Google Patents
Composiciones farmacéuticas de atropina.Info
- Publication number
- CL2019003228A1 CL2019003228A1 CL2019003228A CL2019003228A CL2019003228A1 CL 2019003228 A1 CL2019003228 A1 CL 2019003228A1 CL 2019003228 A CL2019003228 A CL 2019003228A CL 2019003228 A CL2019003228 A CL 2019003228A CL 2019003228 A1 CL2019003228 A1 CL 2019003228A1
- Authority
- CL
- Chile
- Prior art keywords
- atropine
- pharmaceutical compositions
- compositions
- formulations
- free
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/08—Mydriatics or cycloplegics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
Abstract
EL TEMA DE LA INVENCIÓN SE DIRIGE A COMPOSICIONES Y MÉTODOS PARA FORMULACIONES DE ATROPINA EN DOSIS BAJA, ESTÉRILES Y ESTABLES EN ALMACENAMIENTO, CON ESTABILIDAD MEJORADA. PREFERENTEMENTE, LAS COMPOSICIONES PRESENTADAS EN EL PRESENTE DOCUMENTO ESTÁN SUSTANCIALMENTE LIBRES DE PRESERVANTES Y EXHIBEN MENOS DEL 0,35% DE ÁCIDO TRÓPICO POR DEGRADACIÓN DE ATROPINA. VENTAJOSAMENTE, LAS FORMULACIONES CONTEMPLADAS TAMBIÉN ESTÁN SUSTANCIALMENTE LIBRES DE PRESERVANTES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762505027P | 2017-05-11 | 2017-05-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2019003228A1 true CL2019003228A1 (es) | 2020-01-31 |
Family
ID=64096170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019003228A CL2019003228A1 (es) | 2017-05-11 | 2019-11-11 | Composiciones farmacéuticas de atropina. |
Country Status (24)
Country | Link |
---|---|
US (12) | US10251875B2 (es) |
EP (2) | EP3548000B1 (es) |
JP (5) | JP6557379B2 (es) |
KR (1) | KR102281667B1 (es) |
CN (1) | CN110621298B (es) |
AU (1) | AU2018265257B2 (es) |
BR (1) | BR112019023515A2 (es) |
CA (1) | CA3063228C (es) |
CL (1) | CL2019003228A1 (es) |
CO (1) | CO2019012893A2 (es) |
CY (1) | CY1124880T1 (es) |
ES (1) | ES2901140T3 (es) |
HR (1) | HRP20212019T1 (es) |
HU (1) | HUE056595T2 (es) |
LT (1) | LT3548000T (es) |
MX (1) | MX2019013218A (es) |
PH (1) | PH12019502701A1 (es) |
PL (1) | PL3548000T3 (es) |
PT (1) | PT3548000T (es) |
RS (1) | RS62817B1 (es) |
RU (1) | RU2745603C1 (es) |
SG (1) | SG11201910085UA (es) |
SI (1) | SI3548000T1 (es) |
WO (1) | WO2018209051A1 (es) |
Families Citing this family (29)
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US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
US11382909B2 (en) | 2014-09-05 | 2022-07-12 | Sydnexis, Inc. | Ophthalmic composition |
WO2016196367A1 (en) | 2015-05-29 | 2016-12-08 | Sydnexis, Inc. | D2o stabilized pharmaceutical formulations |
CA3023149A1 (en) * | 2016-05-25 | 2017-11-30 | Singapore Health Services Pte Ltd | Atropine-containing aqueous composition |
CA3063228C (en) | 2017-05-11 | 2022-06-28 | Nevakar Inc. | Atropine pharmaceutical compositions |
JP7227163B2 (ja) | 2017-06-10 | 2023-02-21 | アイノビア,インコーポレイティド | 流体を取扱い、目に流体を送出するための方法および装置 |
CN111757737B (zh) * | 2018-03-14 | 2022-07-08 | 正大天晴药业集团股份有限公司 | 用于治疗三阴性乳腺癌的喹啉衍生物 |
WO2019216395A1 (ja) * | 2018-05-11 | 2019-11-14 | 千寿製薬株式会社 | 眼科用組成物 |
WO2020219707A1 (en) * | 2019-04-24 | 2020-10-29 | Allergan, Inc. | Compositions and methods for treatment of ocular conditions |
WO2021001806A1 (en) * | 2019-07-04 | 2021-01-07 | Ocular Discovery Ltd. | Stable dipyridamole formulations with reduced impurities |
US20230041788A1 (en) * | 2019-12-16 | 2023-02-09 | Sydnexis, Inc. | Ophthalmic compositions comprising d2o |
CN110917133A (zh) * | 2019-12-23 | 2020-03-27 | 河北科技大学 | 一种治疗近视的滴眼剂及其制备方法 |
CN115515553A (zh) * | 2020-05-05 | 2022-12-23 | 宝洁公司 | 包含二羧酸的口腔护理组合物 |
CN111821259A (zh) * | 2020-07-14 | 2020-10-27 | 艾尔健康眼药(辽宁)有限公司 | 一种眼用药物组合物 |
CN111840221A (zh) * | 2020-08-25 | 2020-10-30 | 安徽博诺美科生物医药有限公司 | 一种硫酸阿托品滴眼液 |
WO2022130033A1 (en) * | 2020-12-17 | 2022-06-23 | Sun Pharmaceutical Industries Limited | An aqueous sterile solution of atropine for ophthalmic use |
EP4308080A1 (en) * | 2021-03-16 | 2024-01-24 | Vyluma Inc. | Multi-dose container for ophthalmic compositions |
EP4088714A1 (en) * | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic pharmaceutical composition comprising atropine |
EP4088713A1 (en) * | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic pharmaceutical composition comprising atropine |
CN113440486B (zh) * | 2021-06-02 | 2022-12-20 | 苏州欧康维视生物科技有限公司 | 一种用于预防或治疗眼科疾病的滴眼剂组合物及其制备方法 |
WO2023086878A1 (en) * | 2021-11-10 | 2023-05-19 | Visus Therapeutics, Inc. | Carbachol formulations to enhance anti-presbyopia effects |
CN114129511A (zh) * | 2021-12-07 | 2022-03-04 | 河南润弘制药股份有限公司 | 一种具有改进稳定性的硫酸阿托品注射液 |
WO2023152642A1 (en) * | 2022-02-08 | 2023-08-17 | Avaca Pharma Private Limited | Ophthalmic compositions and methods thereof |
US20230277521A1 (en) * | 2022-03-07 | 2023-09-07 | Harrow Ip, Llc | Extended-release pharmaceutical compositions for treating eye conditions |
CN114569551A (zh) * | 2022-03-21 | 2022-06-03 | 杭州赫尔斯科技有限公司 | 阿托品滴眼液及其制备方法 |
WO2023201315A2 (en) * | 2022-04-14 | 2023-10-19 | TearClear Corp. | Ophthalmic agent in preservative removal device |
CN115177584A (zh) * | 2022-07-14 | 2022-10-14 | 成都市海通药业有限公司 | 一种硫酸阿托品注射液的制备方法 |
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LU86521A1 (fr) | 1986-07-18 | 1988-02-02 | Oreal | Procede de teinture des cheveux avec des colorants hydroxyquinoniques et des sels metalliques |
IL85312A (en) | 1988-02-03 | 1991-08-16 | Israel State | Injectable pharmaceutical compositions having improved stability |
JP2617508B2 (ja) * | 1988-02-05 | 1997-06-04 | エーザイ株式会社 | 安定なジフェンヒドラミン含有水溶液 |
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US5716952A (en) * | 1992-03-18 | 1998-02-10 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of muscarinic antagonists |
SE9401108D0 (sv) * | 1994-03-31 | 1994-03-31 | Leiras Oy | Ophthalmic composition I |
US20030129083A1 (en) | 1997-11-26 | 2003-07-10 | Advanced Medical Optics, Inc. | Multi purpose contact lens care compositions including propylene glycol or glycerin |
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KR20150110775A (ko) * | 2013-01-31 | 2015-10-02 | 센주 세이야꾸 가부시키가이샤 | 안정한 수성액제 |
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WO2015055301A1 (en) * | 2013-10-15 | 2015-04-23 | Pharmathen S.A. | Preservative free pharmaceutical compositions for ophthalmic administration |
US9421199B2 (en) * | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
US20160009705A1 (en) | 2014-06-24 | 2016-01-14 | Sydnexis, Inc. | Ophthalmic composition |
WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
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WO2016187426A1 (en) | 2015-05-19 | 2016-11-24 | Amorphex Therapeutics Llc | A device that delivers a sustained low-dose of a myopia-suppressing drug |
KR20180014825A (ko) * | 2015-06-18 | 2018-02-09 | 프레스바이오피아 세라피스, 엘엘씨 | 눈의 굴절 이상 치료 및 원거리 시력 개선용 조성물 및 방법 |
CA3023149A1 (en) | 2016-05-25 | 2017-11-30 | Singapore Health Services Pte Ltd | Atropine-containing aqueous composition |
CA3063228C (en) | 2017-05-11 | 2022-06-28 | Nevakar Inc. | Atropine pharmaceutical compositions |
US11191751B1 (en) | 2020-10-08 | 2021-12-07 | Ads Therapeutics Llc | Topical ophthalmological atropine free base compositions |
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2018
- 2018-05-10 CA CA3063228A patent/CA3063228C/en active Active
- 2018-05-10 ES ES18798073T patent/ES2901140T3/es active Active
- 2018-05-10 KR KR1020197036249A patent/KR102281667B1/ko active IP Right Review Request
- 2018-05-10 BR BR112019023515A patent/BR112019023515A2/pt active Search and Examination
- 2018-05-10 MX MX2019013218A patent/MX2019013218A/es unknown
- 2018-05-10 HU HUE18798073A patent/HUE056595T2/hu unknown
- 2018-05-10 JP JP2018091739A patent/JP6557379B2/ja active Active
- 2018-05-10 US US15/976,279 patent/US10251875B2/en active Active
- 2018-05-10 WO PCT/US2018/032017 patent/WO2018209051A1/en unknown
- 2018-05-10 SI SI201830521T patent/SI3548000T1/sl unknown
- 2018-05-10 RU RU2019139290A patent/RU2745603C1/ru active
- 2018-05-10 PL PL18798073T patent/PL3548000T3/pl unknown
- 2018-05-10 HR HRP20212019TT patent/HRP20212019T1/hr unknown
- 2018-05-10 PT PT187980735T patent/PT3548000T/pt unknown
- 2018-05-10 LT LTEPPCT/US2018/032017T patent/LT3548000T/lt unknown
- 2018-05-10 AU AU2018265257A patent/AU2018265257B2/en active Active
- 2018-05-10 EP EP18798073.5A patent/EP3548000B1/en active Active
- 2018-05-10 RS RS20211580A patent/RS62817B1/sr unknown
- 2018-05-10 EP EP21205568.5A patent/EP3970694A1/en active Pending
- 2018-05-10 SG SG11201910085U patent/SG11201910085UA/en unknown
- 2018-05-10 CN CN201880031247.6A patent/CN110621298B/zh active Active
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2019
- 2019-02-20 US US16/280,585 patent/US10610525B2/en active Active
- 2019-02-20 US US16/280,669 patent/US10576074B2/en active Active
- 2019-02-20 US US16/280,405 patent/US10583132B2/en active Active
- 2019-02-20 US US16/280,552 patent/US11071732B2/en active Active
- 2019-02-20 US US16/280,384 patent/US10568875B2/en active Active
- 2019-07-11 JP JP2019129403A patent/JP6681502B2/ja active Active
- 2019-07-11 JP JP2019129396A patent/JP6865476B2/ja active Active
- 2019-07-11 JP JP2019129405A patent/JP6681503B2/ja active Active
- 2019-11-11 CL CL2019003228A patent/CL2019003228A1/es unknown
- 2019-11-18 CO CONC2019/0012893A patent/CO2019012893A2/es unknown
- 2019-11-28 PH PH12019502701A patent/PH12019502701A1/en unknown
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2020
- 2020-07-20 US US16/933,642 patent/US11464769B2/en active Active
- 2020-08-31 US US17/007,816 patent/US11730727B2/en active Active
- 2020-08-31 US US17/007,900 patent/US11730728B2/en active Active
- 2020-09-09 US US17/016,186 patent/US11707458B2/en active Active
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2021
- 2021-01-11 US US17/145,589 patent/US11642338B2/en active Active
- 2021-03-30 JP JP2021056894A patent/JP7332179B2/ja active Active
- 2021-12-23 CY CY20211101132T patent/CY1124880T1/el unknown
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2023
- 2023-06-28 US US18/343,636 patent/US20230355604A1/en active Pending
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