CY1123841T1 - Μεθοδοι και συσκευες για μεταμοσχευση κυτταρων - Google Patents

Μεθοδοι και συσκευες για μεταμοσχευση κυτταρων

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Publication number
CY1123841T1
CY1123841T1 CY20201100596T CY201100596T CY1123841T1 CY 1123841 T1 CY1123841 T1 CY 1123841T1 CY 20201100596 T CY20201100596 T CY 20201100596T CY 201100596 T CY201100596 T CY 201100596T CY 1123841 T1 CY1123841 T1 CY 1123841T1
Authority
CY
Cyprus
Prior art keywords
chamber
porous scaffold
cells
vascular
pores
Prior art date
Application number
CY20201100596T
Other languages
English (en)
Inventor
Craig Hasilo
Justin Leushner
Daniel Nicholas Haworth
Simon Shohet
Philip Michael Toleikis
Delfina Maria Mazzuca Siroen
Original Assignee
Sernova Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sernova Corporation filed Critical Sernova Corporation
Publication of CY1123841T1 publication Critical patent/CY1123841T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/0676—Pancreatic cells
    • C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
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    • A61M2039/0282—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body with implanted tubes connected to the port
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Abstract

Περιγράφονται συσκευές για την εμφύτευση κυττάρων σε ένα σώμα ξενιστή. Η συσκευή περιλαμβάνει ένα πορώδες ικρίωμα που περιλαμβάνει τουλάχιστον έναν θάλαμο που έχει ένα εγγύτερο και ένα απομακρυσμένο άκρο, πόρους τέτοιου μεγέθους που διευκολύνει την ανάπτυξη των αγγειακών και των συνδετικών ιστών σε τουλάχιστον έναν θάλαμο και ένα πλέγμα πολυπροπυλενίου. Ένα τμήμα του πορώδους ικριώματος επικαλύπτεται με ένα ή περισσότερα υλικά που διεγείρουν την ενσωμάτωση του ιστού και την αγγειογένεση. Μια άλλη συσκευή περιλαμβάνει ένα πορώδες ικρίωμα που περιλαμβάνει τουλάχιστον έναν θάλαμο που έχει ένα εγγύτερο και ένα απομακρυσμένο άκρο, πόρους τέτοιου μεγέθους που διευκολύνει την ανάπτυξη των αγγειακών και των συνδετικών ιστών σε τουλάχιστον έναν θάλαμο, τουλάχιστον ένα αφαιρούμενο βύσμα που είναι διαμορφωμένο, έτσι ώστε να τοποθετείται εντός τουλάχιστον ενός θαλάμου και ενός πλέγματος πολυπροπυλενίου. Τα βλαστοκύτταρα που συγκροτούν τον θάλαμο είναι ανώριμα, μερικώς διαφοροποιημένα ή πλήρως διαφοροποιημένα.
CY20201100596T 2009-08-28 2020-06-26 Μεθοδοι και συσκευες για μεταμοσχευση κυτταρων CY1123841T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23801109P 2009-08-28 2009-08-28
PCT/US2010/047028 WO2011025977A2 (en) 2009-08-28 2010-08-27 Methods and devices for cellular transplantation
EP10751750.0A EP2470228B1 (en) 2009-08-28 2010-08-27 Methods and devices for cellular transplantation

Publications (1)

Publication Number Publication Date
CY1123841T1 true CY1123841T1 (el) 2022-03-24

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CY20171101306T CY1119719T1 (el) 2009-08-28 2017-12-13 Μεθοδοι και συσκευες για μεταμοσχευση κυτταρων
CY20201100596T CY1123841T1 (el) 2009-08-28 2020-06-26 Μεθοδοι και συσκευες για μεταμοσχευση κυτταρων

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US (5) US9011899B2 (el)
EP (2) EP2470228B1 (el)
JP (7) JP5756108B2 (el)
KR (5) KR101785743B1 (el)
CN (1) CN102596273B (el)
AU (1) AU2010286531B2 (el)
BR (1) BR112012004385B1 (el)
CA (1) CA2772375C (el)
CY (2) CY1119719T1 (el)
DK (2) DK3290061T3 (el)
EA (3) EA201992021A1 (el)
ES (2) ES2653241T3 (el)
HK (1) HK1247860A1 (el)
HR (2) HRP20171926T1 (el)
HU (2) HUE051328T2 (el)
IL (1) IL218360A (el)
IN (1) IN2012DN02668A (el)
LT (2) LT2470228T (el)
MX (2) MX353390B (el)
NO (1) NO2470228T3 (el)
NZ (2) NZ598701A (el)
PL (2) PL3290061T3 (el)
PT (2) PT2470228T (el)
SG (3) SG10201405256VA (el)
SI (2) SI2470228T1 (el)
WO (1) WO2011025977A2 (el)

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