BR112013029800A2 - tratamento de degeneração do disco intervertebral com o uso de células derivadas do tecido do tecido do cordão umbilical humano - Google Patents
tratamento de degeneração do disco intervertebral com o uso de células derivadas do tecido do tecido do cordão umbilical humanoInfo
- Publication number
- BR112013029800A2 BR112013029800A2 BR112013029800A BR112013029800A BR112013029800A2 BR 112013029800 A2 BR112013029800 A2 BR 112013029800A2 BR 112013029800 A BR112013029800 A BR 112013029800A BR 112013029800 A BR112013029800 A BR 112013029800A BR 112013029800 A2 BR112013029800 A2 BR 112013029800A2
- Authority
- BR
- Brazil
- Prior art keywords
- tissue
- treatment
- umbilical cord
- cells derived
- intervertebral disc
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/225—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
-
- A—HUMAN NECESSITIES
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- A61K2121/00—Preparations for use in therapy
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
Abstract
abstract not avaible
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/111,933 US20110280838A1 (en) | 2007-12-27 | 2011-05-19 | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
US13/111,933 | 2011-05-19 | ||
PCT/US2012/038407 WO2012158952A1 (en) | 2011-05-19 | 2012-05-17 | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013029800A2 true BR112013029800A2 (pt) | 2017-01-17 |
BR112013029800B1 BR112013029800B1 (pt) | 2021-11-16 |
Family
ID=46208792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013029800-6A BR112013029800B1 (pt) | 2011-05-19 | 2012-05-17 | Usos de uma população homogênea isolada de células derivadas do tecido do cordão umbilical e um hidrogel e do referido hidrogel |
Country Status (15)
Country | Link |
---|---|
US (2) | US20110280838A1 (pt) |
EP (1) | EP2709637B1 (pt) |
JP (1) | JP6100245B2 (pt) |
KR (1) | KR101914918B1 (pt) |
CN (2) | CN110841109A (pt) |
AU (1) | AU2012255270B2 (pt) |
BR (1) | BR112013029800B1 (pt) |
CA (1) | CA2836637C (pt) |
ES (1) | ES2625041T3 (pt) |
MX (1) | MX348245B (pt) |
PL (1) | PL2709637T3 (pt) |
RU (1) | RU2645079C2 (pt) |
SG (2) | SG10201603965VA (pt) |
WO (1) | WO2012158952A1 (pt) |
ZA (1) | ZA201309546B (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090169597A1 (en) * | 2007-12-27 | 2009-07-02 | Ethicon, Incorporated | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
EP2664337B1 (en) | 2005-09-27 | 2019-08-14 | TissueTech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
US8956829B2 (en) | 2013-01-25 | 2015-02-17 | Warsaw Orthopedic, Inc. | Human recombinant growth and differentiaton factor-5 (rhGDF-5) |
US9051389B2 (en) | 2013-01-25 | 2015-06-09 | Warsaw Orthopedic, Inc. | Expression conditions and methods of human recombinant growth and differentiation factor-5 (rhGDF-5) |
US9169308B2 (en) | 2013-01-25 | 2015-10-27 | Warsaw Orthopedic, Inc. | Methods and compositions of human recombinant growth and differentiation factor-5 (rhGDF-5) isolated from inclusion bodies |
US9359417B2 (en) | 2013-01-25 | 2016-06-07 | Warsaw Orthopedic, Inc. | Cell cultures and methods of human recombinant growth and differentiaton factor-5 (rhGDF-5) |
US8945872B2 (en) | 2013-01-25 | 2015-02-03 | Warsaw Orthopedic, Inc. | Methods of purifying human recombinant growth and differentiation factor-5 (rhGDF-5) protein |
US9993506B1 (en) * | 2013-03-16 | 2018-06-12 | BioDlogics, Inc. | Methods for the treatment of degenerative disc diseases by human birth tissue material composition |
WO2016138025A2 (en) | 2015-02-23 | 2016-09-01 | Tissuetech, Inc. | Apparatuses and methods for treating ophthalmic diseases and disorders |
TW201733600A (zh) | 2016-01-29 | 2017-10-01 | 帝聖工業公司 | 胎兒扶持組織物及使用方法 |
US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
US10426796B2 (en) | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
US10616914B2 (en) * | 2017-01-06 | 2020-04-07 | Qualcomm Incorporated | Unicast data transmission on a downlink common burst of a slot using mini-slots |
US11690834B2 (en) | 2017-06-23 | 2023-07-04 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Composition, uses, and methods of treating spinal disc degeneration through sonic hedgehog signaling pathway |
EP3720451A4 (en) * | 2017-12-07 | 2021-07-07 | Vericel Corporation | COMPOSITIONS AND PROCEDURES FOR REPAIRING CARTILAGE DEFECTS |
CN108653328A (zh) * | 2018-03-26 | 2018-10-16 | 杭州市萧山区中医院 | 间充质干细胞联合富血小板血浆在制备用于促进肩袖损伤腱骨复合体愈合的药物中的应用 |
KR102169924B1 (ko) * | 2019-03-26 | 2020-10-26 | 연세대학교 산학협력단 | 연골세포 분화 유도용 조성물 및 이의 용도 |
JP7474520B2 (ja) * | 2019-04-05 | 2024-04-25 | ザ・ユニバーシティ・オブ・ホンコン | 哺乳類の拡大ポテンシャル幹細胞のための培地、その組成物および方法 |
KR102216035B1 (ko) * | 2019-06-19 | 2021-02-16 | 박종철 | 추모를 위한 형상 제조용 골분이 함유된 3d 프린터용 필라멘트 조성물, 이를 이용한 3d 프린터용 필라멘트의 제조방법 및 이로부터 제조되는 3d 프린터용 필라멘트 |
CN110585243A (zh) * | 2019-08-12 | 2019-12-20 | 丰泽康生物医药(深圳)有限公司 | 用于治疗糖皮质激素依赖性皮炎的多潜能细胞活性物与富血小板血浆复合物及制法和应用 |
CN112641996B (zh) * | 2021-01-11 | 2023-08-01 | 常州市第二人民医院 | 髓核间充质干细胞联合壳聚糖纤维凝胶支架的制备方法 |
WO2023168080A1 (en) | 2022-03-04 | 2023-09-07 | Vericel Corporation | Methods and devices for repairing cartilage defects |
WO2023209458A1 (en) | 2022-04-28 | 2023-11-02 | Iceta - Instituto De Ciências, Tecnologias E Agroambiente Da Universidade Do Porto | Process for preparation of human umbilical cord blood plasma and culture media for tissue regeneration |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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US5047055A (en) * | 1990-12-21 | 1991-09-10 | Pfizer Hospital Products Group, Inc. | Hydrogel intervertebral disc nucleus |
US20090169597A1 (en) * | 2007-12-27 | 2009-07-02 | Ethicon, Incorporated | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
CA2515862A1 (en) * | 2003-02-14 | 2004-09-02 | Depuy Spine, Inc. | In-situ formed intervertebral fusion device |
US7875272B2 (en) * | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US11395865B2 (en) * | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
US20060275273A1 (en) * | 2004-02-20 | 2006-12-07 | Seyedin Mitchell S | Intervertebral Disc Repair, Methods and Devices Therefor |
WO2006071777A2 (en) * | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Soft tissue repair and regeneration using postpartum-derived cells and cell products |
RU2301677C1 (ru) * | 2005-12-09 | 2007-06-27 | ЗАО "РеМеТэкс" | Биотрансплантат для лечения дегенеративных и травматических заболеваний хрящевой ткани и способ его получения |
CN101980714A (zh) * | 2008-03-31 | 2011-02-23 | 奥古斯蒂努斯·巴德 | 借助干细胞或骨髓细胞进行组织再生的方法和组合物 |
US8858932B2 (en) * | 2008-06-25 | 2014-10-14 | Mesoblast, Inc. | Repair and/or reconstitution of invertebral discs |
EP2398394B1 (en) * | 2009-02-20 | 2021-08-04 | Omrix Biopharmaceuticals Ltd. | Device for administering an at least two-component substance |
US9198953B2 (en) | 2009-08-14 | 2015-12-01 | Eu Sol Biotech Co., Ltd. | Method for repairing neurodegeneration |
-
2011
- 2011-05-19 US US13/111,933 patent/US20110280838A1/en not_active Abandoned
-
2012
- 2012-05-17 ES ES12725939.8T patent/ES2625041T3/es active Active
- 2012-05-17 AU AU2012255270A patent/AU2012255270B2/en not_active Ceased
- 2012-05-17 BR BR112013029800-6A patent/BR112013029800B1/pt not_active IP Right Cessation
- 2012-05-17 EP EP12725939.8A patent/EP2709637B1/en not_active Not-in-force
- 2012-05-17 PL PL12725939T patent/PL2709637T3/pl unknown
- 2012-05-17 WO PCT/US2012/038407 patent/WO2012158952A1/en active Application Filing
- 2012-05-17 KR KR1020137033719A patent/KR101914918B1/ko active IP Right Grant
- 2012-05-17 JP JP2014511548A patent/JP6100245B2/ja not_active Expired - Fee Related
- 2012-05-17 CN CN201910903413.3A patent/CN110841109A/zh active Pending
- 2012-05-17 CN CN201280024401.XA patent/CN103717226A/zh active Pending
- 2012-05-17 SG SG10201603965VA patent/SG10201603965VA/en unknown
- 2012-05-17 SG SG2013082391A patent/SG194825A1/en unknown
- 2012-05-17 MX MX2013013560A patent/MX348245B/es active IP Right Grant
- 2012-05-17 RU RU2013156357A patent/RU2645079C2/ru active
- 2012-05-17 CA CA2836637A patent/CA2836637C/en not_active Expired - Fee Related
-
2013
- 2013-12-18 ZA ZA2013/09546A patent/ZA201309546B/en unknown
-
2016
- 2016-11-21 US US15/357,539 patent/US20180344900A9/en not_active Abandoned
Also Published As
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CN103717226A (zh) | 2014-04-09 |
CN110841109A (zh) | 2020-02-28 |
WO2012158952A8 (en) | 2014-01-03 |
US20180344900A9 (en) | 2018-12-06 |
AU2012255270A1 (en) | 2013-11-28 |
KR101914918B1 (ko) | 2018-11-05 |
MX348245B (es) | 2017-06-05 |
AU2012255270B2 (en) | 2017-03-23 |
BR112013029800B1 (pt) | 2021-11-16 |
ZA201309546B (en) | 2015-12-23 |
SG10201603965VA (en) | 2016-07-28 |
MX2013013560A (es) | 2013-12-16 |
US20170065745A1 (en) | 2017-03-09 |
EP2709637B1 (en) | 2017-03-22 |
JP2014516034A (ja) | 2014-07-07 |
KR20140043398A (ko) | 2014-04-09 |
US20110280838A1 (en) | 2011-11-17 |
CA2836637A1 (en) | 2012-11-22 |
PL2709637T3 (pl) | 2017-08-31 |
CA2836637C (en) | 2021-07-06 |
EP2709637A1 (en) | 2014-03-26 |
RU2645079C2 (ru) | 2018-02-15 |
RU2013156357A (ru) | 2015-06-27 |
ES2625041T3 (es) | 2017-07-18 |
WO2012158952A1 (en) | 2012-11-22 |
SG194825A1 (en) | 2013-12-30 |
JP6100245B2 (ja) | 2017-03-22 |
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