CY1123393T1 - Ενωσεις, συνθεσεις και μεθοδοι για τη θεραπεια ή την προληψη της ροδοχρωμης ακμης - Google Patents
Ενωσεις, συνθεσεις και μεθοδοι για τη θεραπεια ή την προληψη της ροδοχρωμης ακμηςInfo
- Publication number
- CY1123393T1 CY1123393T1 CY20201100775T CY201100775T CY1123393T1 CY 1123393 T1 CY1123393 T1 CY 1123393T1 CY 20201100775 T CY20201100775 T CY 20201100775T CY 201100775 T CY201100775 T CY 201100775T CY 1123393 T1 CY1123393 T1 CY 1123393T1
- Authority
- CY
- Cyprus
- Prior art keywords
- independently hydrogen
- treatment
- alkyl
- compounds
- alkoxy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 title 1
- 206010000496 acne Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 7
- 239000001257 hydrogen Substances 0.000 abstract 7
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 241001303601 Rosacea Species 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- -1 mists Substances 0.000 abstract 2
- 201000004700 rosacea Diseases 0.000 abstract 2
- 239000000443 aerosol Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000006072 paste Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Παρέχονται τοπικές συνθέσεις για τη θεραπεία της ροδόχρωμης ακμής που περιλαμβάνουν ενώσεις που συμβολίζονται με τους παρακάτω τύπους, συμπεριλαμβανομένων των φαρμακευτικώς αποδεκτών αλάτων αυτών: Όπου καθένα από τα R1 , R2 και R3 είναι ανεξάρτητα υδρογόνο, αλογόνο, αλκύλιο ή αλκοξύ· καθένα από τα R4 και R5 είναι ανεξάρτητα υδρογόνο, αλκύλιο ή αλκοξύ· και καθένα από τα R6 και R7 είναι ανεξάρτητα υδρογόνο, νίτρο, αλκύλιο ή αλκοξύ· Όπου καθένα από τα Α1, A3 και Α4 είναι ανεξάρτητα υδρογόνο ή αλκύλιο· και το Α2 είναι ανεξάρτητα υδρογόνο ή υδροξύ· και όπου καθένα από τα Β1, Β2 και Β3 είναι ανεξάρτητα υδρογόνο, υδροξύ ή αλκοξύ· και καθένα από τα Β4 και B5 είναι ανεξάρτητα υδρογόνο ή υποκατεστημένο αλκύλιο. Κατά τη χρήση τους για τη θεραπεία της ροδόχρωμης ακμής, οι ενώσεις πρόκειται να εφαρμοστούν τοπικά ως σπρέι, ομίχλες, αεροζόλ, διαλύματα, λοσιόν, ζελέδες, κρέμες, αλοιφές, πάστες, επαλείψεις, γαλακτώματα και αιωρήματα.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47361103P | 2003-05-27 | 2003-05-27 | |
US10/853,585 US7439241B2 (en) | 2003-05-27 | 2004-05-25 | Compounds, formulations, and methods for treating or preventing rosacea |
EP04753601.6A EP1631293B2 (en) | 2003-05-27 | 2004-05-26 | Compounds, formulations, and methods for treating or preventing rosacea |
PCT/US2004/016799 WO2004105703A2 (en) | 2003-05-27 | 2004-05-26 | Compounds, formulations, and methods for treating or preventing rosacea |
EP11175578.1A EP2388007B1 (en) | 2003-05-27 | 2004-05-26 | Topical composition for use in the treatment of rosacea-induced redness |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1123393T1 true CY1123393T1 (el) | 2021-12-31 |
Family
ID=33457481
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100049T CY1112242T1 (el) | 2003-05-27 | 2012-01-17 | Ενωσεις, φαρμακοτεχνικες μορφες και μεθοδοι θεραπειας ή αποτροπhς ροδοχρωμης ακμης |
CY2014028C CY2014028I2 (el) | 2003-05-27 | 2014-07-31 | Ενωσεις, φαρμακοτεχνικες μορφες και μεθοδοι θεραπειας ή αποτροπhς ροδοχρωμης ακμης |
CY20201100775T CY1123393T1 (el) | 2003-05-27 | 2020-08-18 | Ενωσεις, συνθεσεις και μεθοδοι για τη θεραπεια ή την προληψη της ροδοχρωμης ακμης |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100049T CY1112242T1 (el) | 2003-05-27 | 2012-01-17 | Ενωσεις, φαρμακοτεχνικες μορφες και μεθοδοι θεραπειας ή αποτροπhς ροδοχρωμης ακμης |
CY2014028C CY2014028I2 (el) | 2003-05-27 | 2014-07-31 | Ενωσεις, φαρμακοτεχνικες μορφες και μεθοδοι θεραπειας ή αποτροπhς ροδοχρωμης ακμης |
Country Status (22)
Country | Link |
---|---|
US (13) | US7439241B2 (el) |
EP (3) | EP2388007B1 (el) |
CN (4) | CN101816793B (el) |
AT (1) | ATE530185T1 (el) |
AU (1) | AU2004242967C1 (el) |
CA (1) | CA2530938C (el) |
CY (3) | CY1112242T1 (el) |
DK (3) | DK2388007T3 (el) |
ES (3) | ES2376172T5 (el) |
HK (3) | HK1084591A1 (el) |
HR (1) | HRP20150957T1 (el) |
HU (3) | HUE051833T2 (el) |
IL (1) | IL172612A (el) |
LT (1) | LT2815748T (el) |
LU (1) | LU92462I2 (el) |
MX (1) | MXPA05014107A (el) |
NO (1) | NO333468B1 (el) |
NZ (1) | NZ544300A (el) |
PL (3) | PL2815748T3 (el) |
PT (3) | PT1631293E (el) |
SI (3) | SI1631293T2 (el) |
WO (1) | WO2004105703A2 (el) |
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PL1761266T3 (pl) * | 2004-05-25 | 2013-09-30 | Galderma Pharma Sa | Związki, preparaty i sposoby leczenia lub zapobiegania procesom zapalnym skóry |
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