CY1122615T1 - Θεραπεια με βλαστοκυτταρα σε παθολογιες τουενδομητριου - Google Patents
Θεραπεια με βλαστοκυτταρα σε παθολογιες τουενδομητριουInfo
- Publication number
- CY1122615T1 CY1122615T1 CY20191100753T CY191100753T CY1122615T1 CY 1122615 T1 CY1122615 T1 CY 1122615T1 CY 20191100753 T CY20191100753 T CY 20191100753T CY 191100753 T CY191100753 T CY 191100753T CY 1122615 T1 CY1122615 T1 CY 1122615T1
- Authority
- CY
- Cyprus
- Prior art keywords
- stem cells
- endometrial
- endometrium
- therapy
- diseases
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 210000004696 endometrium Anatomy 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 230000002357 endometrial effect Effects 0.000 abstract 4
- 230000008929 regeneration Effects 0.000 abstract 3
- 238000011069 regeneration method Methods 0.000 abstract 3
- 210000001185 bone marrow Anatomy 0.000 abstract 2
- 206010051909 Endometrial atrophy Diseases 0.000 abstract 1
- 208000002777 Gynatresia Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 210000000685 uterine artery Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462013121P | 2014-06-17 | 2014-06-17 | |
| PCT/IB2015/001715 WO2015193737A1 (en) | 2014-06-17 | 2015-06-05 | Stem cell therapy in endometrial pathologies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1122615T1 true CY1122615T1 (el) | 2021-03-12 |
Family
ID=54329860
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20191100753T CY1122615T1 (el) | 2014-06-17 | 2019-07-16 | Θεραπεια με βλαστοκυτταρα σε παθολογιες τουενδομητριου |
| CY20221100258T CY1125938T1 (el) | 2014-06-17 | 2022-04-05 | Θεραπεια με βλαστοκυτταρα σε παθολογιες του ενδομητριου |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20221100258T CY1125938T1 (el) | 2014-06-17 | 2022-04-05 | Θεραπεια με βλαστοκυτταρα σε παθολογιες του ενδομητριου |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US11129851B2 (enExample) |
| EP (3) | EP3158057B1 (enExample) |
| JP (2) | JP6920062B2 (enExample) |
| CN (2) | CN116747241A (enExample) |
| AU (1) | AU2015275798B2 (enExample) |
| BR (1) | BR112016029558A2 (enExample) |
| CA (1) | CA2952559C (enExample) |
| CY (2) | CY1122615T1 (enExample) |
| DK (2) | DK3569697T3 (enExample) |
| ES (3) | ES2736117T3 (enExample) |
| HR (3) | HRP20191240T1 (enExample) |
| HU (3) | HUE067463T2 (enExample) |
| LT (2) | LT3569697T (enExample) |
| MX (1) | MX377300B (enExample) |
| PL (3) | PL4012023T3 (enExample) |
| PT (2) | PT3158057T (enExample) |
| RS (3) | RS59210B1 (enExample) |
| RU (1) | RU2725006C2 (enExample) |
| SI (2) | SI3158057T1 (enExample) |
| SM (3) | SMT201900400T1 (enExample) |
| TR (1) | TR201910410T4 (enExample) |
| WO (1) | WO2015193737A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
| ES2705237T3 (es) | 2012-06-06 | 2019-03-22 | Fundacio Inst De Recerca Biomedica Irb Barcelona | Método para el diagnóstico y el pronóstico de metástasis del cáncer de pulmón |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| DK2906718T3 (da) | 2012-10-12 | 2019-07-01 | Inbiomotion Sl | Fremgangsmåde til diagnose, prognose og behandling af prostatakræftmetastase under anvendelse af c-maf |
| BR112015023510A2 (pt) | 2013-03-15 | 2017-10-10 | Fundacio Inst De Recerca Biomedica Irb Barcelona | método para o diagnóstico, prognóstico e tratamento de câncer metastático |
| ES2736117T3 (es) | 2014-06-17 | 2019-12-26 | Igenomix S L | Tratamiento de células madre en patologías endometriales |
| WO2017223233A1 (en) * | 2016-06-23 | 2017-12-28 | Tithon Biotech, Inc. | Cells expressing parathyroid hormone 1 receptor and uses thereof |
| RU2699029C1 (ru) * | 2018-12-10 | 2019-09-03 | Частное образовательное учреждение дополнительного профессионального образования "Академия медицинского образования имени Федора Ивановича Иноземцева" (ЧОУ ДПО "Академия медицинского образования им. Ф.И. Иноземцева") | Способ использования мезенхимальных стволовых клеток для улучшения состояния рубца на матке |
| RU2741621C1 (ru) * | 2020-09-25 | 2021-01-28 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации | Способ лечения внутриматочных синехий |
| CN117979980A (zh) | 2021-07-23 | 2024-05-03 | 车医科学大学校产学协力团 | 用于预防或治疗阿谢曼综合征的包含分离的线粒体作为活性成分的药物组合物 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69027992D1 (de) | 1989-05-05 | 1996-09-05 | North Sydney Area Health Serv | Steigerung der fruchtbarkeit |
| US6979533B2 (en) | 1992-06-12 | 2005-12-27 | The Trustees Of The University Of Pennsylvania | Determination of endometrial receptivity toward embryo implantation |
| CA2203718A1 (en) | 1997-04-25 | 1998-10-25 | University Of British Columbia | Cadherin-11 as an indicator of viable pregnancy |
| IL127896A0 (en) | 1998-12-31 | 1999-10-28 | Gail Laster | A novel treatment for preeclampsia and related diseases |
| EP1255851A4 (en) | 2000-03-08 | 2004-03-31 | Harvey J Kliman | METHODS FOR DIAGNOSING AND MONITORING ENDOMETRIAL GLANDULAR DEVELOPMENT |
| EP1301195A2 (en) | 2000-05-24 | 2003-04-16 | Schering Aktiengesellschaft | Pharmaceutical use of fibulin-1 |
| US6780594B2 (en) | 2000-09-25 | 2004-08-24 | Schering Aktiengesellschaft | Method for in vitro diagnosis of endometriosis |
| AUPR673001A0 (en) | 2001-07-31 | 2001-08-23 | Prince Henry's Institute Of Medical Research | Pregnancy-related enzyme activity |
| DE10139874A1 (de) | 2001-08-10 | 2003-04-30 | Schering Ag | Humane Mater-Proteine |
| GB0201284D0 (en) | 2002-01-21 | 2002-03-06 | Isis Innovation | Screening methods for contraceptive and fertility agents |
| US20030186300A1 (en) | 2002-03-20 | 2003-10-02 | Ali Akoum | Methods and products for modulation of reproductive processes and for diagnosis, prognostication and treatment of related conditions |
| US20040005612A1 (en) | 2002-05-14 | 2004-01-08 | Giudice Linda C. | Endometrial genes in endometrial disorders |
| ES2273061T3 (es) | 2002-08-02 | 2007-05-01 | Schering Aktiengesellschaft | Agentes moduladores de receptores de progesterona con actividad antigonadotropa elevada para el control de fertilidad femenina y para la terapia por reemplazo hormonal. |
| DE10236405A1 (de) | 2002-08-02 | 2004-02-19 | Schering Ag | Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie |
| EP1579007B1 (de) | 2002-12-21 | 2015-05-27 | Universität Leipzig | Verfahren und mittel zur bestimmung von bestimmten zuständen bzw. veränderungen im uterusepithel und im epithel anderer organe |
| EP1660228A1 (en) | 2003-08-21 | 2006-05-31 | PamGene B.V. | Microarray support for bioprobe synthesis |
| WO2005026324A2 (en) | 2003-09-08 | 2005-03-24 | The Board Of Regents Of The University Of Texas System | Method and composition for enhancing in vitro embryo development by supplementing culture medium with prostaglandin or a prostaglandin analog |
| CN1863905A (zh) | 2003-09-08 | 2006-11-15 | 得克萨斯系统大学董事会 | 通过用前列腺素或前列腺素类似物补充培养基加强体外胚发育的方法以及组合物 |
| WO2005061725A1 (en) | 2003-12-23 | 2005-07-07 | Mount Sinai Hospital | Methods for detecting markers associated with endometrial disease or phase |
| AU2005249504A1 (en) | 2004-05-28 | 2005-12-15 | Laboratoires Serono Sa | Use of IL-17 in the treatment of fertility-related disorders |
| CN101460199B (zh) * | 2006-03-31 | 2011-06-08 | 皇家飞利浦电子股份有限公司 | 利用超短t2*弛豫进行细胞测量的系统和方法 |
| JP2007278750A (ja) | 2006-04-04 | 2007-10-25 | Ono Pharmaceut Co Ltd | プロスタグランジン類及びその類縁体の定量方法 |
| US20120269774A1 (en) * | 2006-09-21 | 2012-10-25 | Medistem Laboratories, Inc | Allogeneic stem cell transplants in non-conditioned recipients |
| GB0703683D0 (en) * | 2007-02-26 | 2007-04-04 | Ark Therapeutics Ltd | The treatment of complications in pregnancy |
| US9259233B2 (en) * | 2007-04-06 | 2016-02-16 | Hologic, Inc. | Method and device for distending a gynecological cavity |
| WO2009143633A1 (en) | 2008-05-30 | 2009-12-03 | Institut De Recherches Cliniques De Montreal | Pcsk9 inhibitors and methods of use thereof |
| WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
| WO2013166281A1 (en) * | 2012-05-02 | 2013-11-07 | Cedars-Sinai Medical Center | Bi-functional compositions for targeting cells to diseased tissues and methods of using same |
| EP2348318A1 (en) | 2010-01-21 | 2011-07-27 | Equipo Ivi Investigación, S.L. | Diagnostic method for endometrial receptivity |
| ES2662571T3 (es) | 2011-10-21 | 2018-04-09 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Métodos de evaluación de la receptividad endometrial de una paciente tras una hiperestimulación ovárica controlada |
| AU2012346594B2 (en) | 2011-11-30 | 2017-12-21 | Agency For Science, Technology And Research | GM1 ganglioside to Annexin V microparticle polypeptide ratio for biological monitoring |
| CN104412107B (zh) | 2012-06-27 | 2018-06-08 | 弗·哈夫曼-拉罗切有限公司 | 用sFlt-1/PlGF或内皮糖蛋白/PlGF比值来排除先兆子痫在某时期内发病的手段和方法 |
| RU2515475C1 (ru) * | 2012-11-15 | 2014-05-10 | Федеральное государственное бюджетное учреждение науки ИНСТИТУТ ЦИТОЛОГИИ РОССИЙСКОЙ АКАДЕМИИ НАУК | Способ стимуляции образования децидуальной оболочки эндометрия в эксперименте |
| CA2943284A1 (en) | 2014-03-21 | 2015-11-05 | Igenomix S.L. | Early detection of preeclampsia |
| ES2736117T3 (es) | 2014-06-17 | 2019-12-26 | Igenomix S L | Tratamiento de células madre en patologías endometriales |
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2015
- 2015-06-05 ES ES15781411T patent/ES2736117T3/es active Active
- 2015-06-05 ES ES22150013T patent/ES2983444T3/es active Active
- 2015-06-05 HR HRP20191240 patent/HRP20191240T1/hr unknown
- 2015-06-05 RS RSP20190913 patent/RS59210B1/sr unknown
- 2015-06-05 PL PL22150013.5T patent/PL4012023T3/pl unknown
- 2015-06-05 SI SI201530822T patent/SI3158057T1/sl unknown
- 2015-06-05 CN CN202310575540.1A patent/CN116747241A/zh active Pending
- 2015-06-05 RU RU2017101147A patent/RU2725006C2/ru active
- 2015-06-05 CA CA2952559A patent/CA2952559C/en active Active
- 2015-06-05 EP EP15781411.2A patent/EP3158057B1/en active Active
- 2015-06-05 HR HRP20240798TT patent/HRP20240798T1/hr unknown
- 2015-06-05 SM SM20190400T patent/SMT201900400T1/it unknown
- 2015-06-05 AU AU2015275798A patent/AU2015275798B2/en active Active
- 2015-06-05 CN CN201580043147.1A patent/CN107073040A/zh active Pending
- 2015-06-05 PT PT15781411T patent/PT3158057T/pt unknown
- 2015-06-05 TR TR2019/10410T patent/TR201910410T4/tr unknown
- 2015-06-05 HR HRP20220419TT patent/HRP20220419T1/hr unknown
- 2015-06-05 SM SM20220155T patent/SMT202200155T1/it unknown
- 2015-06-05 EP EP22150013.5A patent/EP4012023B1/en active Active
- 2015-06-05 SM SM20240270T patent/SMT202400270T1/it unknown
- 2015-06-05 HU HUE22150013A patent/HUE067463T2/hu unknown
- 2015-06-05 PT PT191693092T patent/PT3569697T/pt unknown
- 2015-06-05 PL PL15781411T patent/PL3158057T3/pl unknown
- 2015-06-05 JP JP2016573587A patent/JP6920062B2/ja active Active
- 2015-06-05 PL PL19169309T patent/PL3569697T3/pl unknown
- 2015-06-05 HU HUE15781411 patent/HUE044823T2/hu unknown
- 2015-06-05 DK DK19169309.2T patent/DK3569697T3/da active
- 2015-06-05 WO PCT/IB2015/001715 patent/WO2015193737A1/en not_active Ceased
- 2015-06-05 LT LTEP19169309.2T patent/LT3569697T/lt unknown
- 2015-06-05 RS RS20240690A patent/RS65719B1/sr unknown
- 2015-06-05 DK DK15781411.2T patent/DK3158057T3/da active
- 2015-06-05 MX MX2016016756A patent/MX377300B/es active IP Right Grant
- 2015-06-05 RS RS20220339A patent/RS63093B1/sr unknown
- 2015-06-05 HU HUE19169309A patent/HUE058328T2/hu unknown
- 2015-06-05 LT LTEP15781411.2T patent/LT3158057T/lt unknown
- 2015-06-05 EP EP19169309.2A patent/EP3569697B8/en active Active
- 2015-06-05 BR BR112016029558A patent/BR112016029558A2/pt not_active Application Discontinuation
- 2015-06-05 SI SI201531822T patent/SI3569697T1/sl unknown
- 2015-06-05 ES ES19169309T patent/ES2910306T3/es active Active
- 2015-06-05 US US15/318,825 patent/US11129851B2/en active Active
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2019
- 2019-07-16 CY CY20191100753T patent/CY1122615T1/el unknown
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2020
- 2020-06-12 JP JP2020102340A patent/JP2020138984A/ja active Pending
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2022
- 2022-04-05 CY CY20221100258T patent/CY1125938T1/el unknown
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