MX2016016756A - Terapia con células madre en patologías endometriales. - Google Patents
Terapia con células madre en patologías endometriales.Info
- Publication number
- MX2016016756A MX2016016756A MX2016016756A MX2016016756A MX2016016756A MX 2016016756 A MX2016016756 A MX 2016016756A MX 2016016756 A MX2016016756 A MX 2016016756A MX 2016016756 A MX2016016756 A MX 2016016756A MX 2016016756 A MX2016016756 A MX 2016016756A
- Authority
- MX
- Mexico
- Prior art keywords
- endometrial
- stem cell
- cell therapy
- pathologies
- regeneration
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
Abstract
La presente invención se refiere generalmente a la habilidad de células madre derivadas de médula ósea de CD113+ autólogas (BMDSC) para inducir la regeneración del endometrio y tratar patologías endometriales tales como el síndrome de Asherman y atrofia endometrial; métodos para inducir la regeneración endometrial se proporcionan, los cuales comprenden la administración de una cantidad efectiva de células madre derivadas de médula ósea de CD133+ autólogas (BMDSC) en arterias uterinas de un sujeto en necesidad de las mismas para inducir la regeneración del endometrio.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462013121P | 2014-06-17 | 2014-06-17 | |
PCT/IB2015/001715 WO2015193737A1 (en) | 2014-06-17 | 2015-06-05 | Stem cell therapy in endometrial pathologies |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016016756A true MX2016016756A (es) | 2017-11-02 |
Family
ID=54329860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016016756A MX2016016756A (es) | 2014-06-17 | 2015-06-05 | Terapia con células madre en patologías endometriales. |
Country Status (21)
Country | Link |
---|---|
US (1) | US11129851B2 (es) |
EP (3) | EP4012023B1 (es) |
JP (2) | JP6920062B2 (es) |
CN (2) | CN107073040A (es) |
AU (1) | AU2015275798B2 (es) |
BR (1) | BR112016029558A2 (es) |
CA (1) | CA2952559C (es) |
CY (1) | CY1122615T1 (es) |
DK (2) | DK3158057T3 (es) |
ES (2) | ES2910306T3 (es) |
HR (2) | HRP20220419T1 (es) |
HU (2) | HUE044823T2 (es) |
LT (2) | LT3158057T (es) |
MX (1) | MX2016016756A (es) |
PL (2) | PL3569697T3 (es) |
PT (2) | PT3158057T (es) |
RS (2) | RS59210B1 (es) |
RU (1) | RU2725006C2 (es) |
SI (2) | SI3569697T1 (es) |
TR (1) | TR201910410T4 (es) |
WO (1) | WO2015193737A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
ES2705237T3 (es) | 2012-06-06 | 2019-03-22 | Fundacio Inst De Recerca Biomedica Irb Barcelona | Método para el diagnóstico y el pronóstico de metástasis del cáncer de pulmón |
BR112015008255B1 (pt) | 2012-10-12 | 2023-02-28 | Inbiomotion S.L | Métodos in vitro para diagnóstico ou prognóstico de metástase óssea em um indivíduo com câncer de próstata e método para classificar um indivíduo que sofre de câncer de próstata em uma coorte |
US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
US20160040247A1 (en) | 2013-03-15 | 2016-02-11 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Method for the diagnosis, prognosis, and tratment of cancer metastasis |
EP4012023B1 (en) | 2014-06-17 | 2024-05-15 | Asherman Therapy, S.L. | Stem cell therapy in endometrial pathologies |
RU2699029C1 (ru) * | 2018-12-10 | 2019-09-03 | Частное образовательное учреждение дополнительного профессионального образования "Академия медицинского образования имени Федора Ивановича Иноземцева" (ЧОУ ДПО "Академия медицинского образования им. Ф.И. Иноземцева") | Способ использования мезенхимальных стволовых клеток для улучшения состояния рубца на матке |
RU2741621C1 (ru) * | 2020-09-25 | 2021-01-28 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации | Способ лечения внутриматочных синехий |
KR20230015832A (ko) | 2021-07-23 | 2023-01-31 | 차의과학대학교 산학협력단 | 분리된 미토콘드리아를 유효성분으로 포함하는 아셔만 증후군 예방 또는 치료용 약학 조성물 |
Family Cites Families (35)
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EP0473612B1 (en) | 1989-05-05 | 1996-07-31 | Northern Sydney Area Health Service | Fertility enhancement |
US6979533B2 (en) | 1992-06-12 | 2005-12-27 | The Trustees Of The University Of Pennsylvania | Determination of endometrial receptivity toward embryo implantation |
CA2203718A1 (en) | 1997-04-25 | 1998-10-25 | University Of British Columbia | Cadherin-11 as an indicator of viable pregnancy |
IL127896A0 (en) | 1998-12-31 | 1999-10-28 | Gail Laster | A novel treatment for preeclampsia and related diseases |
US6733962B2 (en) | 2000-03-08 | 2004-05-11 | Harvey J. Kliman | Methods of diagnosing and monitoring endometrial glandular development |
JP2004504275A (ja) | 2000-05-24 | 2004-02-12 | シエーリング アクチエンゲゼルシャフト | フィブリン−1の医薬用途 |
US6780594B2 (en) | 2000-09-25 | 2004-08-24 | Schering Aktiengesellschaft | Method for in vitro diagnosis of endometriosis |
AUPR673001A0 (en) | 2001-07-31 | 2001-08-23 | Prince Henry's Institute Of Medical Research | Pregnancy-related enzyme activity |
DE10139874A1 (de) | 2001-08-10 | 2003-04-30 | Schering Ag | Humane Mater-Proteine |
GB0201284D0 (en) | 2002-01-21 | 2002-03-06 | Isis Innovation | Screening methods for contraceptive and fertility agents |
US20030186300A1 (en) | 2002-03-20 | 2003-10-02 | Ali Akoum | Methods and products for modulation of reproductive processes and for diagnosis, prognostication and treatment of related conditions |
WO2004061074A2 (en) | 2002-05-14 | 2004-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Endometrial genes in endometrial disorders |
DE10236405A1 (de) | 2002-08-02 | 2004-02-19 | Schering Ag | Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie |
ES2273061T3 (es) | 2002-08-02 | 2007-05-01 | Schering Aktiengesellschaft | Agentes moduladores de receptores de progesterona con actividad antigonadotropa elevada para el control de fertilidad femenina y para la terapia por reemplazo hormonal. |
AU2003303347A1 (en) | 2002-12-21 | 2004-07-22 | Universitat Leipzig | Method and means for determining specific conditions or changes in the uterine epithelium and in the epithelium of other organs |
EP1660228A1 (en) | 2003-08-21 | 2006-05-31 | PamGene B.V. | Microarray support for bioprobe synthesis |
JP2007504807A (ja) | 2003-09-08 | 2007-03-08 | ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 培養培地にプロスタグランジン又はプロスタグランジン類似物を補足することによってインビトロ胚発生を高めるための方法及び組成 |
EP1670902A4 (en) | 2003-09-08 | 2008-05-07 | Univ Texas | METHOD AND COMPOSITION FOR ENHANCING IN VITRO EMBRYONIC DEVELOPMENT BY ENRICHING A CULTURE MEDIUM COMPRISING PROSTAGLANDIN OR PROSTAGLANDIN ANALOGUE |
AU2004303448A1 (en) | 2003-12-23 | 2005-07-07 | Mount Sinai Hospital | Methods for detecting markers associated with endometrial disease or phase |
US20080014172A1 (en) | 2004-05-28 | 2008-01-17 | Applied Research Systems Ars Holding N.V. | Use of Il-17 in the Treatment of Fertility-Related Disorders |
US20090111140A1 (en) * | 2006-03-31 | 2009-04-30 | Koninklijke Philips Electronics N.V. | Systems and methods for cell measurement utilizing ultrashort t2* |
JP2007278750A (ja) | 2006-04-04 | 2007-10-25 | Ono Pharmaceut Co Ltd | プロスタグランジン類及びその類縁体の定量方法 |
US20120269774A1 (en) * | 2006-09-21 | 2012-10-25 | Medistem Laboratories, Inc | Allogeneic stem cell transplants in non-conditioned recipients |
GB0703683D0 (en) * | 2007-02-26 | 2007-04-04 | Ark Therapeutics Ltd | The treatment of complications in pregnancy |
US9259233B2 (en) * | 2007-04-06 | 2016-02-16 | Hologic, Inc. | Method and device for distending a gynecological cavity |
US8673850B2 (en) | 2008-05-30 | 2014-03-18 | Institut De Recherches Cliniques De Montreal | PCSK9 inhibitors and methods of use thereof |
WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
WO2013166281A1 (en) * | 2012-05-02 | 2013-11-07 | Cedars-Sinai Medical Center | Bi-functional compositions for targeting cells to diseased tissues and methods of using same |
EP2348318A1 (en) | 2010-01-21 | 2011-07-27 | Equipo Ivi Investigación, S.L. | Diagnostic method for endometrial receptivity |
US9453259B2 (en) | 2011-10-21 | 2016-09-27 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for assessing endometrial receptivity of a patient after controlled ovarian hyperstimulation |
SG11201402649QA (en) | 2011-11-30 | 2014-06-27 | Agency Science Tech & Res | Gm1 ganglioside to annexin v microparticle polypeptide ratio for biological monitoring |
KR101996123B1 (ko) | 2012-06-27 | 2019-07-03 | 에프. 호프만-라 로슈 아게 | 특정 시기 내에 임신중독증의 개시를 배제하기 위한 sFlt-1/PlGF 또는 엔도글린/PlGF 비의 적용 수단 및 방법 |
RU2515475C1 (ru) * | 2012-11-15 | 2014-05-10 | Федеральное государственное бюджетное учреждение науки ИНСТИТУТ ЦИТОЛОГИИ РОССИЙСКОЙ АКАДЕМИИ НАУК | Способ стимуляции образования децидуальной оболочки эндометрия в эксперименте |
CN106662589B (zh) | 2014-03-21 | 2019-07-30 | 艾基诺米公司 | 先兆子痫的早期检测 |
EP4012023B1 (en) | 2014-06-17 | 2024-05-15 | Asherman Therapy, S.L. | Stem cell therapy in endometrial pathologies |
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2015
- 2015-06-05 EP EP22150013.5A patent/EP4012023B1/en active Active
- 2015-06-05 HU HUE15781411 patent/HUE044823T2/hu unknown
- 2015-06-05 DK DK15781411.2T patent/DK3158057T3/da active
- 2015-06-05 PL PL19169309T patent/PL3569697T3/pl unknown
- 2015-06-05 RS RSP20190913 patent/RS59210B1/sr unknown
- 2015-06-05 EP EP15781411.2A patent/EP3158057B1/en active Active
- 2015-06-05 JP JP2016573587A patent/JP6920062B2/ja active Active
- 2015-06-05 RS RS20220339A patent/RS63093B1/sr unknown
- 2015-06-05 CN CN201580043147.1A patent/CN107073040A/zh active Pending
- 2015-06-05 MX MX2016016756A patent/MX2016016756A/es active IP Right Grant
- 2015-06-05 PL PL15781411T patent/PL3158057T3/pl unknown
- 2015-06-05 US US15/318,825 patent/US11129851B2/en active Active
- 2015-06-05 PT PT15781411T patent/PT3158057T/pt unknown
- 2015-06-05 CA CA2952559A patent/CA2952559C/en active Active
- 2015-06-05 BR BR112016029558A patent/BR112016029558A2/pt not_active Application Discontinuation
- 2015-06-05 SI SI201531822T patent/SI3569697T1/sl unknown
- 2015-06-05 ES ES19169309T patent/ES2910306T3/es active Active
- 2015-06-05 LT LTEP15781411.2T patent/LT3158057T/lt unknown
- 2015-06-05 HR HRP20220419TT patent/HRP20220419T1/hr unknown
- 2015-06-05 AU AU2015275798A patent/AU2015275798B2/en active Active
- 2015-06-05 DK DK19169309.2T patent/DK3569697T3/da active
- 2015-06-05 SI SI201530822T patent/SI3158057T1/sl unknown
- 2015-06-05 LT LTEP19169309.2T patent/LT3569697T/lt unknown
- 2015-06-05 CN CN202310575540.1A patent/CN116747241A/zh active Pending
- 2015-06-05 WO PCT/IB2015/001715 patent/WO2015193737A1/en active Application Filing
- 2015-06-05 EP EP19169309.2A patent/EP3569697B8/en active Active
- 2015-06-05 PT PT191693092T patent/PT3569697T/pt unknown
- 2015-06-05 RU RU2017101147A patent/RU2725006C2/ru active
- 2015-06-05 HU HUE19169309A patent/HUE058328T2/hu unknown
- 2015-06-05 TR TR2019/10410T patent/TR201910410T4/tr unknown
- 2015-06-05 ES ES15781411T patent/ES2736117T3/es active Active
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2019
- 2019-07-11 HR HRP20191240 patent/HRP20191240T1/hr unknown
- 2019-07-16 CY CY20191100753T patent/CY1122615T1/el unknown
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2020
- 2020-06-12 JP JP2020102340A patent/JP2020138984A/ja active Pending
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