CY1119349T1 - Ομοιοπολικα συζευγματα παραγωγων 1,4-δις-φαινυλαζο-βενζολιου και φαινυλαζο-φαιναζινης ως σκουροχρωμων αποσβεστων μεταφορας ενεργειας δοτη-δεκτη για φθοριζουσα ανιχνευση βιομοριων και φαρμακων - Google Patents

Ομοιοπολικα συζευγματα παραγωγων 1,4-δις-φαινυλαζο-βενζολιου και φαινυλαζο-φαιναζινης ως σκουροχρωμων αποσβεστων μεταφορας ενεργειας δοτη-δεκτη για φθοριζουσα ανιχνευση βιομοριων και φαρμακων

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Publication number
CY1119349T1
CY1119349T1 CY20171100942T CY171100942T CY1119349T1 CY 1119349 T1 CY1119349 T1 CY 1119349T1 CY 20171100942 T CY20171100942 T CY 20171100942T CY 171100942 T CY171100942 T CY 171100942T CY 1119349 T1 CY1119349 T1 CY 1119349T1
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CY
Cyprus
Prior art keywords
finished
fuzzle
cognitive
producer
coffee
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CY20171100942T
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English (en)
Inventor
Ronald M. Cook
Matt Lyttle
Darren Dick
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Biosearch Technologies, Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24268941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1119349(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biosearch Technologies, Inc filed Critical Biosearch Technologies, Inc
Publication of CY1119349T1 publication Critical patent/CY1119349T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • C07C245/08—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with the two nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings, e.g. azobenzene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/46—Phenazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B31/00—Disazo and polyazo dyes of the type A->B->C, A->B->C->D, or the like, prepared by diazotising and coupling
    • C09B31/02—Disazo dyes
    • C09B31/04—Disazo dyes from a coupling component "C" containing a directive amino group
    • C09B31/043—Amino-benzenes
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B56/00—Azo dyes containing other chromophoric systems
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09B56/00—Azo dyes containing other chromophoric systems
    • C09B56/12—Anthraquinone-azo dyes
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Abstract

Η παρούσα εφεύρεση παρέχει μία οικογένεια σκουρόχρωμων αποσβεστών, που ονομάζονται αποσβέστες μαύρης τρύπας (BHQ), οι οποίοι είναι αποτελεσματικοί αποσβέστες της ενέργειας διεγερμένης κατάστασης, αλλά οι ίδιοι είναι ουσιαστικά μη φθορίζοντες. Παρέχονται επίσης μέθοδοι για τη χρήση των BHQ, ιχνηθέτες που ενσωματώνουν τους BHQ και μέθοδοι χρήσης των ιχνηθετών.
CY20171100942T 2000-05-09 2017-09-06 Ομοιοπολικα συζευγματα παραγωγων 1,4-δις-φαινυλαζο-βενζολιου και φαινυλαζο-φαιναζινης ως σκουροχρωμων αποσβεστων μεταφορας ενεργειας δοτη-δεκτη για φθοριζουσα ανιχνευση βιομοριων και φαρμακων CY1119349T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/567,863 US7019129B1 (en) 2000-05-09 2000-05-09 Dark quenchers for donor-acceptor energy transfer
PCT/US2001/015082 WO2001086001A1 (en) 2000-05-09 2001-05-08 Dark quenchers for donor-acceptor energy transfer

Publications (1)

Publication Number Publication Date
CY1119349T1 true CY1119349T1 (el) 2018-03-07

Family

ID=24268941

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20171100942T CY1119349T1 (el) 2000-05-09 2017-09-06 Ομοιοπολικα συζευγματα παραγωγων 1,4-δις-φαινυλαζο-βενζολιου και φαινυλαζο-φαιναζινης ως σκουροχρωμων αποσβεστων μεταφορας ενεργειας δοτη-δεκτη για φθοριζουσα ανιχνευση βιομοριων και φαρμακων
CY20171100957T CY1119330T1 (el) 2000-05-09 2017-09-11 Ομοιοπολικα συζευγματα νουκλεϊκων οξεων με παραγωγα 1,4-δις-φαινυλαζο-βενζολιου και φαινυλαζο-φαιναζινης ως σκουροχρωμους αποσβεστες μεταφορας ενεργειας δεκτη-δοτη για χρηση π.χ. σε αυτοματοποιημενη συνθεση νουκλεϊκων οξεων

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20171100957T CY1119330T1 (el) 2000-05-09 2017-09-11 Ομοιοπολικα συζευγματα νουκλεϊκων οξεων με παραγωγα 1,4-δις-φαινυλαζο-βενζολιου και φαινυλαζο-φαιναζινης ως σκουροχρωμους αποσβεστες μεταφορας ενεργειας δεκτη-δοτη για χρηση π.χ. σε αυτοματοποιημενη συνθεση νουκλεϊκων οξεων

Country Status (8)

Country Link
US (11) US7019129B1 (el)
EP (3) EP1305445B9 (el)
AU (1) AU2001261364A1 (el)
CY (2) CY1119349T1 (el)
DK (3) DK2333113T3 (el)
ES (3) ES2639836T3 (el)
PT (2) PT2333113T (el)
WO (1) WO2001086001A1 (el)

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