CY1116699T1 - Παραγωγα αλφα-αμινοαμιδιου τα οποια ειναι χρησιμα στην αγωγη γνωστικων διαταραχων - Google Patents

Παραγωγα αλφα-αμινοαμιδιου τα οποια ειναι χρησιμα στην αγωγη γνωστικων διαταραχων

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Publication number
CY1116699T1
CY1116699T1 CY20151100827T CY151100827T CY1116699T1 CY 1116699 T1 CY1116699 T1 CY 1116699T1 CY 20151100827 T CY20151100827 T CY 20151100827T CY 151100827 T CY151100827 T CY 151100827T CY 1116699 T1 CY1116699 T1 CY 1116699T1
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CY
Cyprus
Prior art keywords
disease
disorders
cognitive
psychosis
hiv
Prior art date
Application number
CY20151100827T
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English (en)
Inventor
Patricia Salvati
Stefano Rossetti
Luca Benatti
Original Assignee
Newron Pharmaceuticals S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharmaceuticals S.P.A. filed Critical Newron Pharmaceuticals S.P.A.
Publication of CY1116699T1 publication Critical patent/CY1116699T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα εφεύρεση ανήκει στο πεδίο της φαρμακοθεραπείας των γνωστικών ελλειμμάτων στην εκμάθηση και τη μνήμη δια χορήγησης ενός α-αμινοαμιδίου, συγκεκριμένα σαφιναμίδης. Παραδείγματα διαταραχών στη νόηση τα οποία μπορούν να υποβληθούν σε αγωγή με ενώσεις της εφεύρεσης είναι αυτές οι οποίες συσχετίζονται με διαταραχές όπως αυτισμός, δυσλεξία, διαταραχή ελλειμματικής προσοχής-υπερκινητικότητας, σχιζοφρένεια, ιδεοψυχαναγκαστικές διαταραχές, ψύχωση, διπολικές διαταραχές, κατάθλιψη, σύνδρομο Tourette, Ήπια Γνωστική εξασθένηση (MCI) και μαθησιακές διαταραχές σε παιδιά, εφήβους και ενήλικες, Εξασθένηση Μνήμης η οποία Συσχετίζεται με την Ηλικία, Γνωστική Εξασθένηση η οποία Συσχετίζεται με την Ηλικία, Νόσος του Alzheimer, Νόσος του Parkinson, Σύνδρομο Down, Τραυματική Εγκεφαλική βλάβη, Νόσος του Huntington, Προοδευτική Υπερπυρηνική Παράλυση (ΠΥΠ), HIV, εγκεφαλικό επεισόδιο, αγγειακά νοσήματα, νοσήματα του Pick ή του Creutzfeldt-Jacob, σκλήρυνση κατά πλάκας (MS), άλλες διαταραχές λευκής ουσίας και γνωστική επιδείνωση η οποία οφείλεται σε δραστικές ουσίες.
CY20151100827T 2006-06-15 2015-09-22 Παραγωγα αλφα-αμινοαμιδιου τα οποια ειναι χρησιμα στην αγωγη γνωστικων διαταραχων CY1116699T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06012352A EP1870097A1 (en) 2006-06-15 2006-06-15 Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
EP07725989.3A EP2029130B1 (en) 2006-06-15 2007-06-13 Alpha-aminoamide derivatives useful in the treatment of cognitive disorders

Publications (1)

Publication Number Publication Date
CY1116699T1 true CY1116699T1 (el) 2017-03-15

Family

ID=37103353

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100827T CY1116699T1 (el) 2006-06-15 2015-09-22 Παραγωγα αλφα-αμινοαμιδιου τα οποια ειναι χρησιμα στην αγωγη γνωστικων διαταραχων

Country Status (26)

Country Link
US (1) US8741957B2 (el)
EP (4) EP1870097A1 (el)
JP (2) JP2009539908A (el)
KR (1) KR20090018817A (el)
CN (2) CN101466366A (el)
AR (1) AR061505A1 (el)
AU (1) AU2007260239B2 (el)
BR (1) BRPI0712994A2 (el)
CA (1) CA2655243C (el)
CY (1) CY1116699T1 (el)
DK (1) DK2029130T3 (el)
EA (1) EA018006B1 (el)
ES (1) ES2549113T3 (el)
HK (1) HK1170429A1 (el)
HR (1) HRP20151026T1 (el)
HU (1) HUE026484T2 (el)
IL (1) IL195906A (el)
ME (1) ME02343B (el)
MX (1) MX2008016017A (el)
NZ (1) NZ573565A (el)
PL (1) PL2029130T3 (el)
PT (1) PT2029130E (el)
RS (1) RS54324B1 (el)
SI (1) SI2029130T1 (el)
TW (1) TWI494293B (el)
WO (1) WO2007144153A2 (el)

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EP1870097A1 (en) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
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KR101420218B1 (ko) * 2012-06-13 2014-07-17 이우일 생리적안정도 측정 시스템 및 그 방법
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KR101970099B1 (ko) * 2018-02-07 2019-04-17 한국과학기술연구원 척수 손상의 예방 및 치료용 조성물
KR102005019B1 (ko) * 2018-04-04 2019-07-31 한국과학기술연구원 뇌졸중의 예방 및 치료용 조성물
US11090303B2 (en) * 2018-05-15 2021-08-17 Lloyd Hung Loi Tran Therapeutic agent composition and method of use, for treatment of mild congnitive impairment, depression, and psychological disorders
WO2020234275A1 (en) * 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases
US20240277282A1 (en) * 2023-02-17 2024-08-22 Rowan University Automated detection of cognitive conditions

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Also Published As

Publication number Publication date
TWI494293B (zh) 2015-08-01
EP2977046A1 (en) 2016-01-27
HK1170429A1 (en) 2013-03-01
JP2013155186A (ja) 2013-08-15
SI2029130T1 (sl) 2015-11-30
TW200808696A (en) 2008-02-16
RS54324B1 (en) 2016-02-29
WO2007144153A3 (en) 2008-03-13
NZ573565A (en) 2013-01-25
EP2343064A1 (en) 2011-07-13
HUE026484T2 (en) 2016-06-28
ME02343B (me) 2016-06-20
CN102512406B (zh) 2015-01-07
US20100016437A1 (en) 2010-01-21
AU2007260239B2 (en) 2012-08-30
AR061505A1 (es) 2008-09-03
WO2007144153A2 (en) 2007-12-21
AU2007260239A1 (en) 2007-12-21
PL2029130T3 (pl) 2016-01-29
EA200802306A1 (ru) 2009-06-30
HRP20151026T1 (hr) 2015-10-23
PT2029130E (pt) 2015-10-28
IL195906A0 (en) 2009-09-01
MX2008016017A (es) 2009-01-16
EP1870097A1 (en) 2007-12-26
CN101466366A (zh) 2009-06-24
BRPI0712994A2 (pt) 2012-03-27
CN102512406A (zh) 2012-06-27
EA018006B1 (ru) 2013-04-30
EP2029130B1 (en) 2015-08-19
JP2009539908A (ja) 2009-11-19
US8741957B2 (en) 2014-06-03
JP6119068B2 (ja) 2017-04-26
KR20090018817A (ko) 2009-02-23
CA2655243C (en) 2015-06-02
EP2029130A2 (en) 2009-03-04
IL195906A (en) 2016-02-29
DK2029130T3 (en) 2015-11-16
ES2549113T3 (es) 2015-10-23
CA2655243A1 (en) 2007-12-21

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